SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ERM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.62A 2y00A-4ib4A:
27.8		 2y00A-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.67A 2y00B-4ib4A:
27.9		 2y00B-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
PHE A 340
PHE A 341
ASN A 344
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.63A 2y01A-4ib4A:
27.7		 2y01A-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
ASP A 135
SER A 222
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
None
ERM  A2001 ( 4.8A)
 1.28A 2y01A-4ib4A:
27.7		 2y01A-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.63A 2y01B-4ib4A:
27.9		 2y01B-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.54A 2y03A-4ib4A:
27.6		 2y03A-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.55A 2y03B-4ib4A:
28.0		 2y03B-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 11 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.58A 2y04A-4ib4A:
27.6		 2y04A-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.59A 2y04B-4ib4A:
28.0		 2y04B-4ib4A:
28.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
TRP A 337
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
None
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.58A 3d4sA-4ib4A:
27.7		 3d4sA-4ib4A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.56A 3nyaA-4ib4A:
27.5		 3nyaA-4ib4A:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 ASP A 135
SER A 139
THR A 140
ILE A 143
PHE A 341
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
None
ERM  A2001 ( 4.8A)
 0.75A 3rzeA-4ib4A:
26.7		 3rzeA-4ib4A:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 ASP A 135
SER A 139
THR A 140
TRP A 337
PHE A 341
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
None
ERM  A2001 ( 4.8A)
 0.69A 3rzeA-4ib4A:
26.7		 3rzeA-4ib4A:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
ASP A 135
SER A 222
TRP A 337
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
None
ERM  A2001 ( 4.8A)
 1.37A 4amjA-4ib4A:
27.8		 4amjA-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
ASP A 135
VAL A 136
TRP A 337
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.61A 4amjA-4ib4A:
27.8		 4amjA-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
ASP A 135
SER A 222
TRP A 337
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
None
ERM  A2001 ( 4.8A)
 1.38A 4amjB-4ib4A:
28.1		 4amjB-4ib4A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
TRP A 337
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.65A 4amjB-4ib4A:
28.1		 4amjB-4ib4A:
28.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 LEU A 132
ASP A 135
ALA A 225
TRP A 337
PHE A 340
PHE A 341
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.4A)
None
ERM  A2001 (-4.3A)
None
 0.31A 4iaqA-4ib4A:
33.2		 4iaqA-4ib4A:
49.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 209
ALA A 225
TRP A 337
PHE A 340
PHE A 341
 ERM  A2001 (-3.7A)
ERM  A2001 (-3.4A)
None
ERM  A2001 (-4.3A)
None
 1.38A 4iaqA-4ib4A:
33.2		 4iaqA-4ib4A:
49.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 132
ASP A 135
ALA A 225
TRP A 337
PHE A 340
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.4A)
None
ERM  A2001 (-4.3A)
 0.30A 4iarA-4ib4A:
33.2		 4iarA-4ib4A:
49.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		4 / 7 TRP A 131
THR A 140
VAL A 208
PHE A 341
 None
ERM  A2001 (-3.9A)
ERM  A2001 (-4.0A)
None
 0.52A 4iarA-4ib4A:
33.2		 4iarA-4ib4A:
49.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 10 ASP A 135
VAL A 136
PHE A 340
ASN A 344
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.57A 4ldoA-4ib4A:
28.4		 4ldoA-4ib4A:
27.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		12 / 12 LEU A 132
ASP A 135
VAL A 136
SER A 139
VAL A 208
PHE A 217
MET A 218
ALA A 225
TRP A 337
PHE A 340
LEU A 347
VAL A 366
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-4.0A)
ERM  A2001 (-4.6A)
ERM  A2001 (-3.7A)
ERM  A2001 (-3.4A)
None
ERM  A2001 (-4.3A)
ERM  A2001 (-4.2A)
ERM  A2001 ( 4.2A)
 0.24A 4nc3A-4ib4A:
46.7		 4nc3A-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 6 LEU A 209
ASN A 344
GLN A 359
LEU A 362
GLU A 363
 ERM  A2001 (-3.7A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.5A)
 0.65A 4nc3A-4ib4A:
46.7		 4nc3A-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 6 THR A 140
LEU A 209
ASN A 344
GLN A 359
LEU A 362
 ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.1A)
 0.21A 4nc3A-4ib4A:
46.7		 4nc3A-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		12 / 12 LEU A 132
ASP A 135
VAL A 136
SER A 139
VAL A 208
MET A 218
ALA A 225
PHE A 340
PHE A 341
LEU A 347
LEU A 362
VAL A 366
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-4.0A)
ERM  A2001 (-3.7A)
ERM  A2001 (-3.4A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.2A)
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.2A)
 0.40A 5tudA-4ib4A:
38.9		 5tudA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 7 LEU A 209
LYS A 211
ASN A 344
VAL A 348
GLU A 363
 ERM  A2001 (-3.7A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.9A)
ERM  A2001 ( 4.5A)
 0.93A 5tudA-4ib4A:
38.9		 5tudA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 7 THR A 140
LEU A 209
LYS A 211
ASN A 344
VAL A 348
GLN A 359
 ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.9A)
None
 0.44A 5tudA-4ib4A:
38.9		 5tudA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		12 / 12 ASP A 135
SER A 139
VAL A 208
MET A 218
ALA A 225
PHE A 340
PHE A 341
ASN A 344
VAL A 348
GLN A 359
LEU A 362
VAL A 366
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-4.0A)
ERM  A2001 (-3.7A)
ERM  A2001 (-3.4A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.9A)
None
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.2A)
 0.47A 5tudD-4ib4A:
39.2		 5tudD-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 132
PHE A 333
TRP A 337
PHE A 341
TYR A 370
 None
None
None
None
ERM  A2001 ( 4.8A)
 1.41A 6a93A-4ib4A:
36.7		 6a93A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
SER A 139
THR A 140
ILE A 143
PHE A 340
PHE A 341
TYR A 370
 None
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.73A 6a93A-4ib4A:
36.7		 6a93A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
SER A 139
THR A 140
TRP A 337
PHE A 340
PHE A 341
LEU A 362
TYR A 370
 None
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.8A)
 0.76A 6a93A-4ib4A:
36.7		 6a93A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
THR A 140
ILE A 143
PHE A 333
PHE A 340
PHE A 341
TYR A 370
 None
ERM  A2001 (-3.9A)
None
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.90A 6a93A-4ib4A:
36.7		 6a93A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
THR A 140
PHE A 333
TRP A 337
PHE A 340
PHE A 341
LEU A 362
TYR A 370
 None
ERM  A2001 (-3.9A)
None
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.8A)
 0.86A 6a93A-4ib4A:
36.7		 6a93A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
VAL A 136
SER A 139
THR A 140
PHE A 340
PHE A 341
VAL A 366
 None
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.2A)
 0.73A 6a93B-4ib4A:
36.2		 6a93B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
VAL A 136
SER A 139
TRP A 337
PHE A 340
PHE A 341
LEU A 362
VAL A 366
 None
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.1A)
ERM  A2001 ( 4.2A)
 0.82A 6a93B-4ib4A:
36.2		 6a93B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 PHE A 333
TRP A 337
PHE A 340
PHE A 341
ASN A 344
VAL A 366
 None
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.72A 6a94A-4ib4A:
36.7		 6a94A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 SER A 139
GLY A 221
TRP A 337
PHE A 340
PHE A 341
ASN A 344
VAL A 366
 ERM  A2001 (-3.6A)
ERM  A2001 ( 4.3A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.78A 6a94A-4ib4A:
36.7		 6a94A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
SER A 139
GLY A 221
PHE A 340
PHE A 341
ASN A 344
VAL A 366
 None
ERM  A2001 (-3.6A)
ERM  A2001 ( 4.3A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.82A 6a94A-4ib4A:
36.7		 6a94A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
SER A 139
LEU A 209
PHE A 340
VAL A 366
 None
ERM  A2001 (-3.6A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 1.04A 6a94A-4ib4A:
36.7		 6a94A-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 333
TRP A 337
PHE A 340
PHE A 341
VAL A 366
 None
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.2A)
 0.67A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 THR A 140
PHE A 333
TRP A 337
PHE A 341
VAL A 366
 ERM  A2001 (-3.9A)
None
None
None
ERM  A2001 ( 4.2A)
 1.11A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 VAL A 136
SER A 139
GLY A 221
TRP A 337
PHE A 340
PHE A 341
VAL A 366
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 ( 4.3A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.2A)
 0.75A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 136
SER A 139
LEU A 209
PHE A 340
VAL A 366
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.98A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 VAL A 136
SER A 139
THR A 140
GLY A 221
TRP A 337
PHE A 341
VAL A 366
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 ( 4.3A)
None
None
ERM  A2001 ( 4.2A)
 0.88A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 136
SER A 139
THR A 140
LEU A 209
PHE A 340
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.3A)
 0.92A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 136
SER A 139
THR A 140
LEU A 209
VAL A 366
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
ERM  A2001 ( 4.2A)
 0.98A 6a94B-4ib4A:
36.3		 6a94B-4ib4A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 ASP A 135
SER A 139
GLY A 221
ALA A 225
PHE A 340
ASN A 344
VAL A 366
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 ( 4.3A)
ERM  A2001 (-3.4A)
ERM  A2001 (-4.3A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.44A 6bqgA-4ib4A:
36.4		 6bqgA-4ib4A:
62.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 ASP A 135
SER A 139
VAL A 208
GLY A 221
ALA A 225
PHE A 340
VAL A 366
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.6A)
ERM  A2001 (-4.0A)
ERM  A2001 ( 4.3A)
ERM  A2001 (-3.4A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
 0.48A 6bqgA-4ib4A:
36.4		 6bqgA-4ib4A:
62.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 5 VAL A 136
THR A 140
LEU A 209
VAL A 348
LEU A 362
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
ERM  A2001 ( 4.9A)
ERM  A2001 ( 4.1A)
 0.73A 6bqgA-4ib4A:
36.4		 6bqgA-4ib4A:
62.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 VAL A 136
THR A 140
PHE A 333
TRP A 337
PHE A 341
TYR A 370
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.9A)
None
None
None
ERM  A2001 ( 4.8A)
 1.03A 6cm4A-4ib4A:
26.9		 6cm4A-4ib4A:
30.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		12 / 12 TRP A 131
LEU A 132
VAL A 136
SER A 139
THR A 140
PHE A 217
ALA A 225
TRP A 337
PHE A 340
ASN A 344
VAL A 366
TYR A 370
 None
None
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-4.6A)
ERM  A2001 (-3.4A)
None
ERM  A2001 (-4.3A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
ERM  A2001 ( 4.8A)
 0.38A 6drxA-4ib4A:
46.2		 6drxA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 136
SER A 139
PHE A 217
TRP A 337
PHE A 341
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-4.6A)
None
None
 1.45A 6drxA-4ib4A:
46.2		 6drxA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		10 / 11 ASP A 135
VAL A 136
SER A 139
THR A 140
VAL A 208
LEU A 209
ALA A 225
PHE A 340
VAL A 366
TYR A 370
 ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-4.0A)
ERM  A2001 (-3.7A)
ERM  A2001 (-3.4A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
ERM  A2001 ( 4.8A)
 0.41A 6dryA-4ib4A:
44.5		 6dryA-4ib4A:
99.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 136
SER A 139
LEU A 209
PHE A 217
PHE A 340
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.6A)
ERM  A2001 (-4.3A)
 1.12A 6drzA-4ib4A:
43.7		 6drzA-4ib4A:
99.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		11 / 12 VAL A 136
SER A 139
THR A 140
VAL A 208
LEU A 209
PHE A 217
PHE A 340
PHE A 341
ASN A 344
VAL A 366
TYR A 370
 ERM  A2001 (-3.8A)
ERM  A2001 (-3.6A)
ERM  A2001 (-3.9A)
ERM  A2001 (-4.0A)
ERM  A2001 (-3.7A)
ERM  A2001 (-4.6A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.2A)
ERM  A2001 ( 4.8A)
 0.55A 6drzA-4ib4A:
43.7		 6drzA-4ib4A:
99.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
ASP A 135
SER A 222
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 1.26A 6h7jA-4ib4A:
27.8		 6h7jA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
ASP A 135
VAL A 136
SER A 222
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.53A 6h7jA-4ib4A:
27.8		 6h7jA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		8 / 12 TRP A 131
ASP A 135
VAL A 136
SER A 222
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.53A 6h7jB-4ib4A:
28.2		 6h7jB-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 TRP A 131
ASP A 135
SER A 222
ASN A 344
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 1.20A 6h7lA-4ib4A:
28.0		 6h7lA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 TRP A 131
ASP A 135
VAL A 136
ASN A 344
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.54A 6h7lA-4ib4A:
28.0		 6h7lA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 TRP A 131
ASP A 135
SER A 222
ASN A 344
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 1.23A 6h7lB-4ib4A:
28.1		 6h7lB-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		6 / 12 TRP A 131
ASP A 135
VAL A 136
ASN A 344
TRP A 367
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 ( 4.8A)
 0.55A 6h7lB-4ib4A:
28.1		 6h7lB-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
ASP A 135
SER A 222
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 ( 4.6A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 1.16A 6h7mA-4ib4A:
28.0		 6h7mA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.45A 6h7mA-4ib4A:
28.0		 6h7mA-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
ASP A 135
VAL A 136
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.2A)
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.44A 6h7mB-4ib4A:
28.2		 6h7mB-4ib4A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
VAL A 136
TRP A 337
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.8A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.47A 6iblA-4ib4A:
28.0		 6iblA-4ib4A:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		7 / 12 TRP A 131
VAL A 136
TRP A 337
PHE A 340
PHE A 341
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.8A)
None
ERM  A2001 (-4.3A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.48A 6iblB-4ib4A:
28.1		 6iblB-4ib4A:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TRP A 131
VAL A 136
PHE A 340
ASN A 344
TYR A 370
 None
ERM  A2001 (-3.8A)
ERM  A2001 (-4.3A)
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.8A)
 0.59A 6mxtA-4ib4A:
28.4		 6mxtA-4ib4A:
25.39