SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ERC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
SER A 204
SER A 207
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
None
 1.31A 2y00A-3pdsA:
38.6		 2y00A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.51A 2y00A-3pdsA:
38.6		 2y00A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 117
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.34A 2y00A-3pdsA:
38.6		 2y00A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.56A 2y00B-3pdsA:
38.3		 2y00B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
None
 1.41A 2y00B-3pdsA:
38.3		 2y00B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 VAL A 114
ASN A 312
TRP A 313
 ERC  A1201 (-3.8A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 1.00A 2y00B-3pdsA:
38.3		 2y00B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 VAL A 117
ASN A 312
TRP A 313
 None
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 0.59A 2y00B-3pdsA:
38.3		 2y00B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
PHE A 193
SER A 203
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 0.52A 2y01A-3pdsA:
38.1		 2y01A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
SER A 204
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.25A 2y01A-3pdsA:
38.1		 2y01A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A 109
ASP A 113
SER A 207
PHE A 289
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.28A 2y01A-3pdsA:
38.1		 2y01A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
None
 1.43A 2y01B-3pdsA:
38.2		 2y01B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.54A 2y01B-3pdsA:
38.2		 2y01B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.32A 2y03A-3pdsA:
38.5		 2y03A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.38A 2y03A-3pdsA:
38.5		 2y03A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 VAL A 117
SER A 204
SER A 207
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.42A 2y03A-3pdsA:
38.5		 2y03A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 117
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.30A 2y03A-3pdsA:
38.5		 2y03A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.30A 2y03B-3pdsA:
38.4		 2y03B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.43A 2y03B-3pdsA:
38.4		 2y03B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 VAL A 117
SER A 204
SER A 207
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.40A 2y03B-3pdsA:
38.4		 2y03B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 117
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.32A 2y03B-3pdsA:
38.4		 2y03B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 11 TRP A 109
ASP A 113
VAL A 114
PHE A 193
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.66A 2y04A-3pdsA:
38.1		 2y04A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 11 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.25A 2y04A-3pdsA:
38.1		 2y04A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 11 VAL A 117
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.39A 2y04A-3pdsA:
38.1		 2y04A-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.26A 2y04B-3pdsA:
38.1		 2y04B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 0.69A 2y04B-3pdsA:
38.1		 2y04B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 VAL A 117
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.43A 2y04B-3pdsA:
38.1		 2y04B-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 204
TYR A 316
 None
ERC  A1201 (-3.7A)
None
ERC  A1201 ( 4.1A)
None
 1.30A 3d4sA-3pdsA:
47.2		 3d4sA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
TYR A 308
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
None
ERC  A1201 (-3.0A)
None
 1.20A 3d4sA-3pdsA:
47.2		 3d4sA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
TRP A 286
PHE A 290
ASN A 293
TYR A 308
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
None
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
ERC  A1201 (-3.0A)
None
 0.68A 3d4sA-3pdsA:
47.2		 3d4sA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 114
ASN A 293
TYR A 308
ASN A 312
TYR A 316
 ERC  A1201 (-3.8A)
ERC  A1201 (-3.5A)
None
ERC  A1201 (-3.0A)
None
 1.41A 3d4sA-3pdsA:
47.2		 3d4sA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.19A 3nyaA-3pdsA:
47.1		 3nyaA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 290
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.8A)
None
 1.40A 3nyaA-3pdsA:
47.1		 3nyaA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.67A 3nyaA-3pdsA:
47.1		 3nyaA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.56A 3nyaA-3pdsA:
47.1		 3nyaA-3pdsA:
99.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 113
THR A 118
ILE A 121
TRP A 286
PHE A 290
TYR A 316
 ERC  A1201 (-3.7A)
None
None
None
ERC  A1201 (-4.8A)
None
 0.58A 3rzeA-3pdsA:
36.2		 3rzeA-3pdsA:
55.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.16A 4amjA-3pdsA:
38.5		 4amjA-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
SER A 203
SER A 207
TRP A 286
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.71A 4amjA-3pdsA:
38.5		 4amjA-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
SER A 203
TRP A 286
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.68A 4amjA-3pdsA:
38.5		 4amjA-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 204
TYR A 316
 None
ERC  A1201 (-3.7A)
None
ERC  A1201 ( 4.1A)
None
 1.33A 4amjA-3pdsA:
38.5		 4amjA-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 114
PHE A 289
ASN A 293
ASN A 312
TYR A 316
 ERC  A1201 (-3.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.21A 4amjA-3pdsA:
38.5		 4amjA-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
SER A 203
PHE A 290
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.8A)
None
 1.49A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
SER A 207
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 0.93A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 203
SER A 207
TRP A 286
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 (-3.7A)
None
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.73A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 203
TRP A 286
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
None
ERC  A1201 (-2.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.69A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 204
TYR A 316
 None
ERC  A1201 (-3.7A)
None
ERC  A1201 ( 4.1A)
None
 1.36A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 114
PHE A 289
ASN A 293
ASN A 312
TYR A 316
 ERC  A1201 (-3.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.19A 4amjB-3pdsA:
38.5		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_2
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 4 VAL A 114
ASP A 192
TYR A 199
TRP A 313
 ERC  A1201 (-3.8A)
ERC  A1201 (-4.2A)
None
ERC  A1201 (-4.4A)
 0.47A 4amjB-3pdsA:
38.4		 4amjB-3pdsA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 TRP A 109
THR A 118
SER A 203
PHE A 290
 None
None
ERC  A1201 (-2.8A)
ERC  A1201 (-4.8A)
 0.57A 4iarA-3pdsA:
29.2		 4iarA-3pdsA:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 114
TRP A 286
PHE A 289
PHE A 290
VAL A 297
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
None
 0.83A 4ib4A-3pdsA:
27.3		 4ib4A-3pdsA:
30.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 10 ASP A 113
VAL A 114
SER A 207
PHE A 289
ASN A 312
TYR A 316
 ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.08A 4ldoA-3pdsA:
32.8		 4ldoA-3pdsA:
58.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 10 ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
PHE A 289
ASN A 312
TYR A 316
 ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 0.74A 4ldoA-3pdsA:
32.8		 4ldoA-3pdsA:
58.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 10 ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
SER A 207
PHE A 289
ASN A 293
ASN A 312
 ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 0.80A 4ldoA-3pdsA:
32.8		 4ldoA-3pdsA:
58.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 VAL A 117
SER A 204
PHE A 289
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.1A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.0A)
None
 1.04A 4ldoA-3pdsA:
32.8		 4ldoA-3pdsA:
58.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 10 VAL A 117
SER A 204
SER A 207
PHE A 289
ASN A 293
ASN A 312
 None
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 1.42A 4ldoA-3pdsA:
32.8		 4ldoA-3pdsA:
58.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 SER A 203
SER A 207
PHE A 193
 ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.4A)
 0.94A 5mugA-3pdsA:
undetectable		 5mugA-3pdsA:
19.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 TRP A 109
THR A 118
ILE A 121
PHE A 282
TRP A 286
PHE A 289
PHE A 290
TYR A 316
 None
None
None
None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
None
 0.69A 6a93A-3pdsA:
28.9		 6a93A-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A 109
VAL A 114
THR A 118
TRP A 286
PHE A 289
PHE A 290
 None
ERC  A1201 (-3.8A)
None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
 0.51A 6a93B-3pdsA:
30.8		 6a93B-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 5 ASP A 113
ILE A 121
PHE A 282
TYR A 316
 ERC  A1201 (-3.7A)
None
None
None
 0.64A 6a93B-3pdsA:
30.8		 6a93B-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 282
TRP A 286
PHE A 289
PHE A 290
ASN A 293
 None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
 0.51A 6a94A-3pdsA:
31.1		 6a94A-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A 109
PHE A 282
TRP A 286
PHE A 289
PHE A 290
 None
None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
 0.50A 6a94A-3pdsA:
31.1		 6a94A-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A 109
SER A 207
PHE A 282
TRP A 286
PHE A 289
 None
ERC  A1201 (-2.7A)
None
None
ERC  A1201 (-4.5A)
 0.74A 6a94A-3pdsA:
31.1		 6a94A-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 114
THR A 118
PHE A 282
TRP A 286
PHE A 289
PHE A 290
 ERC  A1201 (-3.8A)
None
None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
 0.38A 6a94B-3pdsA:
31.3		 6a94B-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 114
THR A 118
SER A 207
PHE A 282
TRP A 286
PHE A 289
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.7A)
None
None
ERC  A1201 (-4.5A)
 0.62A 6a94B-3pdsA:
31.3		 6a94B-3pdsA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 PHE A 282
TRP A 286
PHE A 290
TYR A 308
TYR A 316
 None
None
ERC  A1201 (-4.8A)
None
None
 0.84A 6cm4A-3pdsA:
35.8		 6cm4A-3pdsA:
57.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 203
PHE A 282
TRP A 286
PHE A 290
TYR A 308
 ERC  A1201 (-2.8A)
None
None
ERC  A1201 (-4.8A)
None
 1.06A 6cm4A-3pdsA:
35.8		 6cm4A-3pdsA:
57.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 114
THR A 118
PHE A 282
TRP A 286
PHE A 290
TYR A 316
 ERC  A1201 (-3.8A)
None
None
None
ERC  A1201 (-4.8A)
None
 0.73A 6cm4A-3pdsA:
35.8		 6cm4A-3pdsA:
57.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 114
THR A 118
SER A 203
PHE A 282
TRP A 286
PHE A 290
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-2.8A)
None
None
ERC  A1201 (-4.8A)
 0.92A 6cm4A-3pdsA:
35.8		 6cm4A-3pdsA:
57.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A 109
VAL A 114
THR A 118
TRP A 286
PHE A 289
ASN A 293
 None
ERC  A1201 (-3.8A)
None
None
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
 0.93A 6drxA-3pdsA:
28.5		 6drxA-3pdsA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A 109
VAL A 114
TRP A 286
PHE A 289
ASN A 293
TYR A 316
 None
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
None
 0.82A 6drxA-3pdsA:
28.5		 6drxA-3pdsA:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 114
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 ERC  A1201 (-3.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.60A 6drzA-3pdsA:
28.4		 6drzA-3pdsA:
30.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 114
THR A 118
PHE A 289
PHE A 290
ASN A 293
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
 0.75A 6drzA-3pdsA:
28.4		 6drzA-3pdsA:
30.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 204
SER A 207
PHE A 289
ASN A 293
ASN A 312
 ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 1.35A 6h7jA-3pdsA:
32.1		 6h7jA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A 109
THR A 110
ASP A 113
SER A 203
SER A 207
ASN A 312
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
 1.03A 6h7jA-3pdsA:
32.1		 6h7jA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 204
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 0.58A 6h7jA-3pdsA:
32.1		 6h7jA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 204
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 0.70A 6h7jA-3pdsA:
32.1		 6h7jA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.20A 6h7jA-3pdsA:
32.1		 6h7jA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A 109
THR A 110
ASP A 113
SER A 203
SER A 207
ASN A 312
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
 1.02A 6h7jB-3pdsA:
32.8		 6h7jB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 204
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 0.58A 6h7jB-3pdsA:
32.8		 6h7jB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 204
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 0.70A 6h7jB-3pdsA:
32.8		 6h7jB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.19A 6h7jB-3pdsA:
32.8		 6h7jB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 204
ASN A 293
ASN A 312
TRP A 313
TYR A 316
 ERC  A1201 ( 4.1A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.09A 6h7lA-3pdsA:
32.2		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 204
SER A 207
ASN A 293
ASN A 312
TRP A 313
 ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 1.44A 6h7lA-3pdsA:
32.2		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
ASN A 293
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 0.76A 6h7lA-3pdsA:
32.2		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
ASN A 293
ASN A 312
TRP A 313
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 0.79A 6h7lA-3pdsA:
32.2		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.12A 6h7lA-3pdsA:
32.2		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 GLY A  90
VAL A 117
PHE A 193
PHE A 290
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-4.8A)
 0.63A 6h7lA-3pdsA:
32.3		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 GLY A  90
VAL A 117
PHE A 289
PHE A 290
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
 0.49A 6h7lA-3pdsA:
32.3		 6h7lA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 204
ASN A 293
ASN A 312
TRP A 313
TYR A 316
 ERC  A1201 ( 4.1A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.11A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 SER A 204
SER A 207
ASN A 293
ASN A 312
TRP A 313
 ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 1.45A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
ASN A 293
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 0.77A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
ASN A 293
ASN A 312
TRP A 313
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
 0.79A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
ASN A 312
TRP A 313
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
ERC  A1201 (-4.4A)
None
 1.14A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 GLY A  90
VAL A 117
PHE A 193
PHE A 290
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-4.8A)
 0.65A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 GLY A  90
VAL A 117
PHE A 289
PHE A 290
 ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
 0.48A 6h7lB-3pdsA:
32.6		 6h7lB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 113
SER A 204
PHE A 289
ASN A 293
ASN A 312
TYR A 316
 ERC  A1201 (-3.7A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.04A 6h7mA-3pdsA:
32.3		 6h7mA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 113
SER A 204
SER A 207
PHE A 289
ASN A 293
ASN A 312
 ERC  A1201 (-3.7A)
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 1.45A 6h7mA-3pdsA:
32.3		 6h7mA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 193
SER A 203
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.54A 6h7mA-3pdsA:
32.3		 6h7mA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 193
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 0.58A 6h7mA-3pdsA:
32.3		 6h7mA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.21A 6h7mA-3pdsA:
32.3		 6h7mA-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 113
VAL A 117
SER A 204
ASN A 293
ASN A 312
TYR A 316
 ERC  A1201 (-3.7A)
None
ERC  A1201 ( 4.1A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 1.15A 6h7mB-3pdsA:
32.6		 6h7mB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 113
VAL A 117
SER A 204
SER A 207
ASN A 293
ASN A 312
 ERC  A1201 (-3.7A)
None
ERC  A1201 ( 4.1A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 1.48A 6h7mB-3pdsA:
32.6		 6h7mB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 289
PHE A 290
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.0A)
None
 1.21A 6h7mB-3pdsA:
32.6		 6h7mB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
PHE A 289
PHE A 290
ASN A 293
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
None
 0.60A 6h7mB-3pdsA:
32.6		 6h7mB-3pdsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
SER A 207
PHE A 289
PHE A 290
ASN A 293
ASN A 312
 None
ERC  A1201 (-3.7A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.4A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
ERC  A1201 (-3.0A)
 0.59A 6h7mB-3pdsA:
32.6		 6h7mB-3pdsA:
13.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
PHE A 193
TRP A 286
PHE A 289
PHE A 290
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.2A)
ERC  A1201 (-4.4A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
None
 0.84A 6iblA-3pdsA:
32.2		 6iblA-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
TRP A 286
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.2A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.77A 6iblA-3pdsA:
32.2		 6iblA-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A 113
SER A 203
SER A 207
ASN A 312
 ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
 0.65A 6iblA-3pdsA:
32.2		 6iblA-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
VAL A 114
ASP A 192
PHE A 193
TRP A 286
PHE A 289
PHE A 290
ASN A 293
TYR A 316
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.8A)
ERC  A1201 (-4.2A)
ERC  A1201 (-4.4A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
None
 0.80A 6iblB-3pdsA:
32.5		 6iblB-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
PHE A 193
TRP A 286
PHE A 289
PHE A 290
ASN A 293
 None
ERC  A1201 ( 4.6A)
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.2A)
ERC  A1201 (-4.4A)
None
ERC  A1201 (-4.5A)
ERC  A1201 (-4.8A)
ERC  A1201 (-3.5A)
 0.79A 6iblB-3pdsA:
32.5		 6iblB-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A 113
SER A 203
SER A 207
ASN A 312
 ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
ERC  A1201 (-3.0A)
 0.65A 6iblB-3pdsA:
32.4		 6iblB-3pdsA:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
VAL A 114
ASP A 192
PHE A 193
PHE A 289
ASN A 293
TYR A 308
ILE A 309
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.8A)
ERC  A1201 (-4.2A)
ERC  A1201 (-4.4A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
None
ERC  A1201 (-4.1A)
ERC  A1201 (-3.0A)
None
 0.67A 6mxtA-3pdsA:
33.8		 6mxtA-3pdsA:
57.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A 109
VAL A 114
PHE A 289
ASN A 293
TYR A 308
 None
ERC  A1201 (-3.8A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
None
 1.39A 6mxtA-3pdsA:
33.8		 6mxtA-3pdsA:
57.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A 109
VAL A 114
VAL A 117
ASP A 192
PHE A 193
PHE A 289
ASN A 293
TYR A 308
ASN A 312
TYR A 316
 None
ERC  A1201 (-3.8A)
None
ERC  A1201 (-4.2A)
ERC  A1201 (-4.4A)
ERC  A1201 (-4.5A)
ERC  A1201 (-3.5A)
None
ERC  A1201 (-3.0A)
None
 0.71A 6mxtA-3pdsA:
33.8		 6mxtA-3pdsA:
57.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A 113
SER A 203
SER A 207
 ERC  A1201 (-3.7A)
ERC  A1201 (-2.8A)
ERC  A1201 (-2.7A)
 0.48A 6mxtA-3pdsA:
34.0		 6mxtA-3pdsA:
57.00