SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EP5'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y00_A_Y00A601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 1.09A | 2y00A-6g79S:28.3 | 2y00A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y00_A_Y00A601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.84A | 2y00A-6g79S:28.3 | 2y00A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y00_B_Y00B601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 1.12A | 2y00B-6g79S:28.3 | 2y00B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y00_B_Y00B601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.82A | 2y00B-6g79S:28.3 | 2y00B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y01_A_Y00A601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 7 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TRP S 356TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)NoneEP5 S 401 ( 4.9A) | 1.06A | 2y01A-6g79S:28.2 | 2y01A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y01_B_Y00B601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.80A | 2y01B-6g79S:28.2 | 2y01B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y01_B_Y00B601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.14A | 2y01B-6g79S:28.2 | 2y01B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y03_A_5FWA601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.79A | 2y03A-6g79S:28.3 | 2y03A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y03_A_5FWA601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125ASP S 129SER S 212PHE S 330TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 ( 4.9A) | 0.98A | 2y03A-6g79S:28.3 | 2y03A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y03_B_5FWB601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.76A | 2y03B-6g79S:28.2 | 2y03B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y03_B_5FWB601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125ASP S 129SER S 212PHE S 330TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 ( 4.9A) | 0.98A | 2y03B-6g79S:28.2 | 2y03B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y04_A_68HA601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 11 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.74A | 2y04A-6g79S:28.1 | 2y04A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y04_A_68HA601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 11 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.13A | 2y04A-6g79S:28.1 | 2y04A-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y04_B_68HB601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.65A | 2y04B-6g79S:28.2 | 2y04B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y04_B_68HB601_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.09A | 2y04B-6g79S:28.2 | 2y04B-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3D4S_A_TIMA401_1 (BETA-2 ADRENERGICRECEPTOR/T4-LYSOZYMECHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212TRP S 327PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)NoneEP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.58A | 3d4sA-6g79S:27.9 | 3d4sA-6g79S:9.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NYA_A_JTZA1203_1 (BETA-2 ADRENERGICRECEPTOR, LYSOZYME) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.64A | 3nyaA-6g79S:27.8 | 3nyaA-6g79S:9.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NYA_A_JTZA1203_1 (BETA-2 ADRENERGICRECEPTOR, LYSOZYME) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.00A | 3nyaA-6g79S:27.8 | 3nyaA-6g79S:9.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RZE_A_D7VA1201_1 (HISTAMINE H1RECEPTOR, LYSOZYMECHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | ASP S 129THR S 134TRP S 327PHE S 331TYR S 359 | EP5 S 401 (-3.3A)EP5 S 401 (-3.8A)NoneEP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.83A | 3rzeA-6g79S:28.0 | 3rzeA-6g79S:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AMJ_A_CVDA1359_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.17A | 4amjA-6g79S:28.2 | 4amjA-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AMJ_A_CVDA1359_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 7 / 12 | TRP S 125ASP S 129SER S 212TRP S 327PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.70A | 4amjA-6g79S:28.2 | 4amjA-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AMJ_B_CVDB1360_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 1.16A | 4amjB-6g79S:28.4 | 4amjB-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AMJ_B_CVDB1360_1 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 7 / 12 | TRP S 125ASP S 129SER S 212TRP S 327PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.68A | 4amjB-6g79S:28.4 | 4amjB-6g79S:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AWU_A_4CHA502_0 (OXIDOREDUCTASE,FMN-BINDING) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 4 / 7 | THR S 355TYR S 109LEU S 126PHE S 330 | NoneNoneNoneEP5 S 401 (-4.0A) | 1.35A | 4awuA-6g79S:undetectable | 4awuA-6g79S:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAQ_A_2GMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | ALA S 216TRP S 327PHE S 330PHE S 331PHE S 351 | EP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 (-4.5A) | 1.07A | 4iaqA-6g79S:34.2 | 4iaqA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAQ_A_2GMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 9 / 12 | LEU S 126ASP S 129CYH S 133VAL S 201ALA S 216TRP S 327PHE S 330PHE S 331THR S 355 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-4.2A)EP5 S 401 (-4.1A)EP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)None | 0.63A | 4iaqA-6g79S:34.2 | 4iaqA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAQ_A_2GMA2001_2 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 4 / 6 | TRP S 125ILE S 130THR S 134SER S 212 | NoneEP5 S 401 (-4.2A)EP5 S 401 (-3.8A)EP5 S 401 (-3.3A) | 0.72A | 4iaqA-6g79S:34.2 | 4iaqA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | CYH S 133TRP S 327PHE S 330MET S 337THR S 355 | EP5 S 401 (-4.2A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.0A)None | 1.50A | 4iarA-6g79S:34.6 | 4iarA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 8 / 12 | LEU S 126ASP S 129CYH S 133VAL S 201ALA S 216TRP S 327PHE S 330THR S 355 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-4.2A)EP5 S 401 (-4.1A)EP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A)None | 0.62A | 4iarA-6g79S:34.6 | 4iarA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAR_A_ERMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 7 / 12 | LEU S 126ASP S 129CYH S 133VAL S 201ALA S 216TRP S 327SER S 334 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-4.2A)EP5 S 401 (-4.1A)EP5 S 401 ( 4.0A)NoneEP5 S 401 (-3.6A) | 0.81A | 4iarA-6g79S:34.6 | 4iarA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAR_A_ERMA2001_2 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 4 / 7 | TRP S 125ILE S 130SER S 212PHE S 331 | NoneEP5 S 401 (-4.2A)EP5 S 401 (-3.3A)EP5 S 401 (-4.7A) | 0.74A | 4iarA-6g79S:34.6 | 4iarA-6g79S:95.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAR_A_ERMA2001_2 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 1B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 4 / 7 | TRP S 125ILE S 130THR S 134PHE S 331 | NoneEP5 S 401 (-4.2A)EP5 S 401 (-3.8A)EP5 S 401 (-4.7A) | 0.43A | 4iarA-6g79S:34.6 | 4iarA-6g79S:95.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4IB4_A_ERMA2001_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 2B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | LEU S 126ALA S 216TRP S 327PHE S 330PHE S 331 | NoneEP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 0.50A | 4ib4A-6g79S:28.1 | 4ib4A-6g79S:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4NC3_A_ERMA1202_1 (CHIMERA PROTEIN OFHUMAN5-HYDROXYTRYPTAMINERECEPTOR 2B AND E.COLI SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | LEU S 126ASP S 129ALA S 216TRP S 327PHE S 330 | NoneEP5 S 401 (-3.3A)EP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A) | 0.53A | 4nc3A-6g79S:28.8 | 4nc3A-6g79S:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5TUD_A_ERMA2001_1 (5-HYDROXYTRYPTAMINERECEPTOR 2B,SOLUBLECYTOCHROME B562CHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | LEU S 126ASP S 129ALA S 216PHE S 330PHE S 331 | NoneEP5 S 401 (-3.3A)EP5 S 401 ( 4.0A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 0.45A | 5tudA-6g79S:30.4 | 5tudA-6g79S:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A93_A_8NUA3001_0 (5-HYDROXYTRYPTAMINERECEPTOR 2A,SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 7 / 12 | SER S 106TRP S 125THR S 134TRP S 327PHE S 330PHE S 331TYR S 359 | NoneNoneEP5 S 401 (-3.8A)NoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.81A | 6a93A-6g79S:24.9 | 6a93A-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A93_A_8NUA3001_0 (5-HYDROXYTRYPTAMINERECEPTOR 2A,SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | THR S 134PHE S 323TRP S 327PHE S 330PHE S 331 | EP5 S 401 (-3.8A)NoneNoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 1.34A | 6a93A-6g79S:24.9 | 6a93A-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A93_B_8NUB3001_0 (5-HYDROXYTRYPTAMINERECEPTOR 2A,SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | SER S 106TRP S 125THR S 134PHE S 330PHE S 331 | NoneNoneEP5 S 401 (-3.8A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 0.79A | 6a93B-6g79S:26.4 | 6a93B-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6A93_B_8NUB3001_0 (5-HYDROXYTRYPTAMINERECEPTOR 2A,SOLUBLECYTOCHROME B562) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | SER S 106TRP S 125TRP S 327PHE S 330PHE S 331 | NoneNoneNoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A) | 0.72A | 6a93B-6g79S:26.4 | 6a93B-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6CM4_A_8NUA2001_0 (D(2) DOPAMINERECEPTOR, ENDOLYSINCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | CYH S 133THR S 134PHE S 331TYR S 109TYR S 359 | EP5 S 401 (-4.2A)EP5 S 401 (-3.8A)EP5 S 401 (-4.7A)NoneEP5 S 401 ( 4.9A) | 1.34A | 6cm4A-6g79S:25.8 | 6cm4A-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6CM4_A_8NUA2001_0 (D(2) DOPAMINERECEPTOR, ENDOLYSINCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | CYH S 133THR S 134TRP S 327THR S 355TYR S 359 | EP5 S 401 (-4.2A)EP5 S 401 (-3.8A)NoneNoneEP5 S 401 ( 4.9A) | 0.82A | 6cm4A-6g79S:25.8 | 6cm4A-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6CM4_A_8NUA2001_0 (D(2) DOPAMINERECEPTOR, ENDOLYSINCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | CYH S 133TRP S 327PHE S 331THR S 355TYR S 359 | EP5 S 401 (-4.2A)NoneEP5 S 401 (-4.7A)NoneEP5 S 401 ( 4.9A) | 0.90A | 6cm4A-6g79S:25.8 | 6cm4A-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRILCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | LEU S 126THR S 134ALA S 216TRP S 327PHE S 330TYR S 359 | NoneEP5 S 401 (-3.8A)EP5 S 401 ( 4.0A)NoneEP5 S 401 (-4.0A)EP5 S 401 ( 4.9A) | 0.60A | 6drxA-6g79S:28.9 | 6drxA-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6DRX_A_H8GA1201_0 (5HT2B RECEPTOR, BRILCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125LEU S 126THR S 134ALA S 216TRP S 327TYR S 359 | NoneNoneEP5 S 401 (-3.8A)EP5 S 401 ( 4.0A)NoneEP5 S 401 ( 4.9A) | 0.58A | 6drxA-6g79S:28.9 | 6drxA-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6DRY_A_H8DA2001_0 (5HT2B RECEPTOR, BRILCHIMERA) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 11 | ASP S 129THR S 134ALA S 216PHE S 330TYR S 359 | EP5 S 401 (-3.3A)EP5 S 401 (-3.8A)EP5 S 401 ( 4.0A)EP5 S 401 (-4.0A)EP5 S 401 ( 4.9A) | 0.45A | 6dryA-6g79S:26.5 | 6dryA-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6H7J_A_5FWA401_0 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.75A | 6h7jA-6g79S:32.5 | 6h7jA-6g79S:29.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6H7J_B_5FWB402_0 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.75A | 6h7jB-6g79S:33.1 | 6h7jB-6g79S:29.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6H7M_A_68HA504_0 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.76A | 6h7mA-6g79S:32.7 | 6h7mA-6g79S:29.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6H7M_B_68HB405_0 (BETA-1 ADRENERGICRECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 6 / 12 | TRP S 125ASP S 129SER S 212PHE S 330PHE S 331TYR S 359 | NoneEP5 S 401 (-3.3A)EP5 S 401 (-3.3A)EP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.76A | 6h7mB-6g79S:33.0 | 6h7mB-6g79S:29.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6IBL_A_H98A501_0 (THIOREDOXIN 1,BETA-1ADRENERGIC RECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125TRP S 327PHE S 330PHE S 331TYR S 359 | NoneNoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.51A | 6iblA-6g79S:23.9 | 6iblA-6g79S:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6IBL_B_H98B501_0 (THIOREDOXIN 1,BETA-1ADRENERGIC RECEPTOR) |
6g79 | 5-HYDROXYTRYPTAMINERECEPTOR 1B (Homosapiens) | 5 / 12 | TRP S 125TRP S 327PHE S 330PHE S 331TYR S 359 | NoneNoneEP5 S 401 (-4.0A)EP5 S 401 (-4.7A)EP5 S 401 ( 4.9A) | 0.55A | 6iblB-6g79S:32.6 | 6iblB-6g79S:undetectable |