SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EMU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 VAL A 148
TYR A  80
TYR A  82
ILE A  98
TYR A 120
 None
None
EMU  A 202 (-4.9A)
EMU  A 202 ( 4.9A)
None
 1.12A 1fm4A-4jhiA:
19.8		 1fm4A-4jhiA:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 TYR A  80
TYR A  82
VAL A  84
ILE A  98
TYR A 120
 None
EMU  A 202 (-4.9A)
None
EMU  A 202 ( 4.9A)
None
 0.74A 4a84A-4jhiA:
20.3		 4a84A-4jhiA:
42.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.94A 4eq4A-4jhiA:
undetectable		 4eq4A-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 8 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.94A 4eq4B-4jhiA:
undetectable		 4eq4B-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.91A 4eqlA-4jhiA:
undetectable		 4eqlA-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.93A 4eqlB-4jhiA:
undetectable		 4eqlB-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 6 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.90A 4l39A-4jhiA:
undetectable		 4l39A-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.82A 4l39B-4jhiA:
undetectable		 4l39B-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 10 ILE A  39
LEU A  57
TYR A  82
ARG A 140
GLY A 143
 None
None
EMU  A 202 (-4.9A)
None
None
 1.09A 5mxbA-4jhiA:
20.0		 5mxbA-4jhiA:
28.66