SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EMM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 119
TYR A 334
TRP A 432
ILE A 439
HIS A 440
 EMM  A1999 (-3.5A)
None
None
None
EMM  A1999 ( 3.8A)
 1.24A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 9 TRP A  84
GLU A 199
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 1.38A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 9 TRP A  84
GLY A 117
TRP A 432
ILE A 439
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 1.03A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 9 TRP A  84
GLY A 118
GLU A 199
TYR A 334
TRP A 432
ILE A 439
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
SAF  A1998 (-3.5A)
None
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.59A 1acjA-1gqrA:
67.0		 1acjA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACL_A_DMEA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 10 TYR A  70
TRP A  84
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.65A 1aclA-1gqrA:
66.6		 1aclA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 119
TYR A 121
SER A 200
PHE A 331
HIS A 440
 EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.38A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 TRP A  84
GLU A 199
SER A 200
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.16A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.79A 1ax9A-1gqrA:
71.1		 1ax9A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 ASP A  72
GLY A 118
TYR A 121
SER A 200
PHE A 330
PHE A 331
 None
SAF  A1998 ( 3.5A)
None
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 1.13A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
TRP A 233
PHE A 290
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.43A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.91A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 200
TRP A 233
PHE A 290
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.72A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 TRP A  84
GLY A 117
TRP A 233
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.0A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.35A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 TRP A  84
GLY A 118
SER A 200
TRP A 233
PHE A 330
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 3.8A)
 1.36A 1dx6A-1gqrA:
69.1		 1dx6A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 10 GLY A 118
TYR A 121
GLU A 199
TRP A 279
LEU A 282
PHE A 288
 SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
None
None
EMM  A1999 (-4.3A)
 0.99A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 10 GLY A 119
TYR A 121
TRP A 279
PHE A 331
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
None
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 1.35A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 10 TRP A  84
GLY A 118
TYR A 121
GLU A 199
TRP A 279
LEU A 282
PHE A 330
PHE A 331
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
None
None
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 0.61A 1eveA-1gqrA:
68.9		 1eveA-1gqrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 PHE A 331
PHE A 290
TYR A 421
GLY A 203
SER A 200
GLY A 118
 EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
None
None
EMM  A1999 ( 1.4A)
SAF  A1998 ( 3.5A)
 1.44A 1igxA-1gqrA:
0.0		 1igxA-1gqrA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 PHE A 331
PHE A 290
TYR A 421
GLY A 227
SER A 200
GLY A 118
 EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
None
None
EMM  A1999 ( 1.4A)
SAF  A1998 ( 3.5A)
 1.35A 1igxA-1gqrA:
0.0		 1igxA-1gqrA:
22.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.30A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 290
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
None
EMM  A1999 ( 3.8A)
 0.72A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 TYR A  70
ASP A  72
GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
 None
None
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
 1.16A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TYR A  70
ASP A  72
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
PHE A 290
TYR A 334
 None
None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
None
 0.56A 1maaA-1gqrA:
59.7		 1maaA-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 TRP A  84
GLY A 117
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.25A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 TYR A  70
GLY A 118
TYR A 121
TYR A 130
SER A 200
TRP A 279
PHE A 288
 None
SAF  A1998 ( 3.5A)
None
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.3A)
 1.02A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
PHE A 331
HIS A 440
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.48A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 TYR A  70
TRP A  84
GLY A 118
TYR A 121
TYR A 130
SER A 200
TRP A 279
PHE A 290
PHE A 331
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
None
EMM  A1999 ( 1.4A)
None
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
 0.86A 1maaC-1gqrA:
61.2		 1maaC-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 GLY A 119
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.30A 1maaD-1gqrA:
59.7		 1maaD-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 8 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 0.73A 1maaD-1gqrA:
59.7		 1maaD-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 ASP A  72
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 331
 None
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
 1.33A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		11 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.46A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.01A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.99A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 12 GLY A 202
GLU A 199
SER A 200
PHE A 288
PHE A 290
HIS A 440
 None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.43A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.71A 1qtiA-1gqrA:
71.6		 1qtiA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U65_A_CP0A1000_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 GLN A  74
TRP A  84
TYR A 121
GLU A 199
TRP A 279
LEU A 282
ASP A 285
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
None
None
None
EMM  A1999 ( 3.8A)
 0.94A 1u65A-1gqrA:
68.0		 1u65A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 288
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.42A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 ASP A  72
TRP A  84
GLY A 117
GLY A 118
SER A 200
PHE A 288
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.79A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.08A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.93A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.72A 1w6rA-1gqrA:
68.9		 1w6rA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 ASP A  72
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 330
PHE A 331
 None
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 1.09A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 ASP A  72
TRP A  84
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 330
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
 0.41A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 0.97A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 1.21A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 TRP A  84
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 330
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.65A 1w76A-1gqrA:
69.3		 1w76A-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 10 ASP A  72
TRP A  84
GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 331
 None
SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
 0.44A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 10 GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.3A)
 1.03A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 202
GLU A 199
SER A 200
PHE A 290
HIS A 440
 None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.30A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 10 TRP A  84
GLY A 117
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.69A 1w76B-1gqrA:
69.1		 1w76B-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ALA A 234
PHE A 300
GLY A 207
SER A 200
LEU A 224
 None
None
None
EMM  A1999 ( 1.4A)
None
 0.95A 1ya4A-1gqrA:
52.5		 1ya4A-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 GLY A 117
GLY A 118
GLY A 119
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 0.59A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 118
GLY A 119
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 1.06A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 202
GLY A 117
GLY A 118
SER A 200
ALA A 201
 None
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
 1.09A 1yajC-1gqrA:
49.9		 1yajC-1gqrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 117
GLY A 118
SER A 200
ALA A 201
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 ( 3.8A)
 0.95A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 9 GLY A 118
GLY A 119
SER A 200
ALA A 201
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.06A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 9 GLY A 118
GLY A 119
SER A 200
ALA A 201
TRP A 233
PHE A 288
PHE A 290
PHE A 330
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
EMM  A1999 ( 3.8A)
 0.73A 2aceA-1gqrA:
69.0		 2aceA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 7 GLY A 118
GLU A 199
SER A 200
PHE A 288
 SAF  A1998 ( 3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 1.06A 2ackA-1gqrA:
69.7		 2ackA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 7 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.81A 2ackA-1gqrA:
69.7		 2ackA-1gqrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 ASP A  72
TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 None
SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.76A 2ha2A-1gqrA:
60.6		 2ha2A-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TYR A  70
ASP A  72
TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 None
None
SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.70A 2ha2B-1gqrA:
61.5		 2ha2B-1gqrA:
58.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 TRP A  84
TYR A 121
TYR A 130
GLU A 199
PHE A 331
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
None
None
SAF  A1998 (-3.5A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.75A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 GLY A 118
GLY A 119
ALA A 201
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.12A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 8 GLY A 118
GLY A 119
ALA A 201
TRP A 233
PHE A 288
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 0.67A 2ha4A-1gqrA:
60.4		 2ha4A-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 7 TRP A  84
TYR A 121
TYR A 130
GLU A 199
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
None
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.62A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 7 GLY A 118
GLY A 119
ALA A 201
TRP A 233
PHE A 290
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 (-3.6A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 0.62A 2ha4B-1gqrA:
62.0		 2ha4B-1gqrA:
58.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 9 TYR A  70
TRP A  84
TYR A 121
TRP A 279
PHE A 331
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
None
EMM  A1999 (-4.7A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.82A 2ha6B-1gqrA:
61.5		 2ha6B-1gqrA:
58.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 ILE A 115
GLY A 227
GLY A 198
ASN A 399
PHE A 290
 None
None
None
None
EMM  A1999 (-4.1A)
 1.14A 2okcB-1gqrA:
2.2		 2okcB-1gqrA:
21.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XUD_A_DMEA1544_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 TRP A  84
TYR A 121
TRP A 279
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
None
None
None
EMM  A1999 ( 3.8A)
 0.75A 2xudA-1gqrA:
59.8		 2xudA-1gqrA:
58.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 384
ILE A 394
PHE A 331
PHE A 339
GLY A 338
 None
None
EMM  A1999 (-4.7A)
None
None
 1.45A 3ko0A-1gqrA:
1.4
3ko0C-1gqrA:
1.4		 3ko0A-1gqrA:
11.35
3ko0C-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 GLY A 437
PHE A 290
PHE A 330
GLY A 328
PHE A 331
 None
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
None
EMM  A1999 (-4.7A)
 1.47A 3ko0A-1gqrA:
1.4
3ko0C-1gqrA:
1.4		 3ko0A-1gqrA:
11.35
3ko0C-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 9 PHE A 339
GLY A 338
GLY A 384
ILE A 394
PHE A 331
 None
None
None
None
EMM  A1999 (-4.7A)
 1.41A 3ko0H-1gqrA:
1.4
3ko0I-1gqrA:
1.5		 3ko0H-1gqrA:
11.35
3ko0I-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 PHE A 339
GLY A 338
GLY A 384
ILE A 394
PHE A 331
 None
None
None
None
EMM  A1999 (-4.7A)
 1.42A 3ko0L-1gqrA:
1.3
3ko0N-1gqrA:
1.9		 3ko0L-1gqrA:
11.35
3ko0N-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 384
ILE A 394
PHE A 331
PHE A 339
GLY A 338
 None
None
EMM  A1999 (-4.7A)
None
None
 1.42A 3ko0R-1gqrA:
1.5
3ko0T-1gqrA:
1.3		 3ko0R-1gqrA:
11.35
3ko0T-1gqrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 10 GLY A 437
PHE A 290
PHE A 330
GLY A 328
PHE A 331
 None
EMM  A1999 (-4.1A)
SAF  A1998 (-3.1A)
None
EMM  A1999 (-4.7A)
 1.50A 3ko0R-1gqrA:
1.5
3ko0T-1gqrA:
1.3		 3ko0R-1gqrA:
11.35
3ko0T-1gqrA:
11.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 7 GLY A 118
GLY A 119
SER A 200
TRP A 233
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 ( 3.8A)
 0.56A 3o9mA-1gqrA:
61.5		 3o9mA-1gqrA:
53.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 6 GLY A 118
GLY A 119
SER A 200
TRP A 233
HIS A 440
 SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 ( 3.8A)
 0.62A 3o9mB-1gqrA:
61.5		 3o9mB-1gqrA:
53.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 12 LEU A 127
TYR A 130
SER A 200
SER A 226
PHE A 330
 None
None
EMM  A1999 ( 1.4A)
None
SAF  A1998 (-3.1A)
 1.49A 3ug8A-1gqrA:
undetectable		 3ug8A-1gqrA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 8 GLY A 117
GLY A 118
SER A 200
GLY A 227
VAL A 400
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
None
None
 1.42A 3v1nA-1gqrA:
12.5		 3v1nA-1gqrA:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BDS_A_THAA701_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 9 TRP A  84
GLU A 199
SER A 200
TYR A 334
TRP A 432
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.53A 4bdsA-1gqrA:
59.3		 4bdsA-1gqrA:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.12A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 122
SER A 200
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 0.85A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
SER A 122
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.75A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
SER A 122
SER A 200
PHE A 288
PHE A 290
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
None
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
 0.41A 4ey6A-1gqrA:
61.5		 4ey6A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		8 / 12 GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 331
PHE A 290
HIS A 440
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
EMM  A1999 (-4.1A)
EMM  A1999 ( 3.8A)
 1.11A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 12 GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
 SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
 0.85A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
GLU A 199
SER A 200
PHE A 288
PHE A 290
PHE A 331
HIS A 440
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
EMM  A1999 (-4.7A)
EMM  A1999 ( 3.8A)
 0.79A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 12 TRP A  84
GLY A 117
GLY A 118
GLY A 119
TYR A 121
GLU A 199
SER A 200
PHE A 288
PHE A 290
 SAF  A1998 (-3.8A)
SAF  A1998 (-3.1A)
SAF  A1998 ( 3.5A)
EMM  A1999 (-3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.3A)
EMM  A1999 (-4.1A)
 0.44A 4ey6B-1gqrA:
59.7		 4ey6B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		7 / 11 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
HIS A 440
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.33A 4ey7A-1gqrA:
61.2		 4ey7A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		10 / 11 TYR A  70
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.80A 4ey7A-1gqrA:
61.2		 4ey7A-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 11 GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
HIS A 440
 EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
 1.40A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
HIS A 440
GLY A 441
 SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.84A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 11 TYR A  70
GLY A 119
TYR A 121
SER A 200
TRP A 279
TYR A 334
 None
EMM  A1999 (-3.5A)
None
EMM  A1999 ( 1.4A)
None
None
 1.28A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 11 TYR A  70
TRP A  84
GLY A 118
TYR A 121
GLU A 199
SER A 200
TRP A 279
TYR A 334
GLY A 441
 None
SAF  A1998 (-3.8A)
SAF  A1998 ( 3.5A)
None
SAF  A1998 (-3.5A)
EMM  A1999 ( 1.4A)
None
None
SAF  A1998 ( 4.6A)
 0.69A 4ey7B-1gqrA:
61.1		 4ey7B-1gqrA:
57.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E4J_A_DMEA608_1
(ACETYLCHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		9 / 9 TYR A  70
TRP A  84
TYR A 121
GLU A 199
TRP A 279
PHE A 330
TYR A 334
HIS A 440
GLY A 441
 None
SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
SAF  A1998 (-3.1A)
None
EMM  A1999 ( 3.8A)
SAF  A1998 ( 4.6A)
 0.63A 5e4jA-1gqrA:
68.0		 5e4jA-1gqrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		3 / 3 GLU A 443
TRP A 114
HIS A 440
 None
None
EMM  A1999 ( 3.8A)
 0.96A 5xipA-1gqrA:
1.1		 5xipA-1gqrA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 5 TRP A  84
TYR A 130
GLU A 199
TYR A 334
HIS A 440
 SAF  A1998 (-3.8A)
None
SAF  A1998 (-3.5A)
None
EMM  A1999 ( 3.8A)
 0.57A 6ep4A-1gqrA:
61.9		 6ep4A-1gqrA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		4 / 8 GLY A 118
SER A 200
PHE A 331
TYR A 334
 SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
None
 0.66A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		6 / 8 TRP A  84
GLY A 119
SER A 200
TRP A 233
PHE A 331
TYR A 334
 SAF  A1998 (-3.8A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.7A)
None
 0.59A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 1gqr ACETYLCHOLINESTERASE
(Tetronarce
californica) 		5 / 11 HIS A 440
TYR A 121
GLY A 118
SER A 200
PHE A 331
 EMM  A1999 ( 3.8A)
None
SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
 1.16A 6ieyA-1gqrA:
18.0
6ieyB-1gqrA:
18.4		 6ieyA-1gqrA:
20.34
6ieyB-1gqrA:
20.34