SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ELA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		4 / 5 ILE A 119
ILE A 100
ILE A  93
LEU A  85
 None
None
ELA  A 301 (-4.1A)
None
 0.84A 1zgyA-3lupA:
undetectable		 1zgyA-3lupA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A 167
ALA A 236
GLY A 270
ILE A 198
THR A 120
 None
None
None
None
ELA  A 301 (-4.4A)
 0.96A 3c6gA-3lupA:
undetectable		 3c6gA-3lupA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A 167
ALA A 275
ALA A 236
ILE A 198
THR A 120
 None
ELA  A 301 ( 4.2A)
None
None
ELA  A 301 (-4.4A)
 1.07A 3c6gA-3lupA:
undetectable		 3c6gA-3lupA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A 167
ALA A 275
ALA A 236
ILE A 198
THR A 120
 None
ELA  A 301 ( 4.2A)
None
None
ELA  A 301 (-4.4A)
 1.09A 3czhB-3lupA:
undetectable		 3czhB-3lupA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 12 VAL A 161
ALA A 273
GLY A 272
TYR A  49
HIS A 268
 None
None
None
None
ELA  A 301 (-3.6A)
 1.11A 3qxyA-3lupA:
undetectable		 3qxyA-3lupA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 12 VAL A 161
ALA A 273
GLY A 272
TYR A  49
HIS A 268
 None
None
None
None
ELA  A 301 (-3.6A)
 1.12A 3rc0B-3lupA:
undetectable		 3rc0B-3lupA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3lup DEGV FAMILY PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ILE A  28
VAL A  25
THR A 117
ILE A 119
ILE A  89
 ELA  A 301 ( 4.5A)
None
None
None
None
 1.19A 3um5B-3lupA:
undetectable		 3um5B-3lupA:
21.32