SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EJ4'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4ej4 DELTA-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Mus
musculus) 		5 / 12 ASP A 128
TYR A 129
ILE A 136
TRP A 274
TYR A 308
 EJ4  A 500 (-3.0A)
EJ4  A 500 (-4.4A)
None
EJ4  A 500 (-4.5A)
EJ4  A 500 (-3.8A)
 0.81A 3rzeA-4ej4A:
32.7		 3rzeA-4ej4A:
52.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ej4 DELTA-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA
(Mus
musculus;
Escherichia
virus
T4) 		4 / 5 ASP A 128
ILE A 136
PHE A 270
TYR A 308
 EJ4  A 500 (-3.0A)
None
None
EJ4  A 500 (-3.8A)
 0.63A 6a93B-4ej4A:
27.9		 6a93B-4ej4A:
25.53