SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EFE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 ASN A 310
ASN A 275
ARG A  91
 None
None
EFE  A 701 (-4.0A)
 0.92A 2rlcA-3qlbA:
undetectable		 2rlcA-3qlbA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		4 / 7 ARG A 277
ASP A  93
PHE A 241
ARG A  91
 None
None
None
EFE  A 701 (-4.0A)
 1.35A 3kivA-3qlbA:
undetectable		 3kivA-3qlbA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 3qlb ENANTIO-PYOCHELIN
RECEPTOR
(Pseudomonas
fluorescens) 		3 / 3 PHE A  92
ASP A  93
LYS A 121
 EFE  A 701 (-4.7A)
None
None
 0.77A 6awtD-3qlbA:
2.4		 6awtD-3qlbA:
12.09