SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EF2'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CI1_B_EF2B1429_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 10 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 4ci1B-4tzcC:
0.0		 4ci1B-4tzcC:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CI2_B_LVYB1429_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 9 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 4ci2B-4tzcC:
0.0		 4ci2B-4tzcC:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CI3_B_Y70B1429_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 10 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 4ci3B-4tzcC:
0.0		 4ci3B-4tzcC:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZ4_C_LVYC502_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 9 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.27A 4tz4C-4tzcC:
0.0		 4tz4C-4tzcC:
33.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_A_Y70A504_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.11A 4tzuA-4tzcC:
20.6		 4tzuA-4tzcC:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.22A 4tzuB-4tzcC:
20.1
4tzuC-4tzcC:
20.0		 4tzuB-4tzcC:
100.00
4tzuC-4tzcC:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.19A 4tzuB-4tzcC:
20.1
4tzuC-4tzcC:
20.0		 4tzuB-4tzcC:
100.00
4tzuC-4tzcC:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TZU_D_Y70D503_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.18A 4tzuD-4tzcC:
20.3		 4tzuD-4tzcC:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		4 / 7 TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.31A 4v32A-4tzcC:
15.9		 4v32A-4tzcC:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		4 / 7 TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.26A 4v32B-4tzcC:
15.9		 4v32B-4tzcC:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		4 / 7 TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.37A 4v32C-4tzcC:
15.3		 4v32C-4tzcC:
33.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		4 / 8 SER C 381
TRP C 382
TRP C 388
TRP C 402
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
 0.27A 5amiB-4tzcC:
15.9		 5amiB-4tzcC:
33.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FQD_E_LVYE1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 12 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5fqdE-4tzcC:
17.1
5fqdF-4tzcC:
2.2		 5fqdE-4tzcC:
33.02
5fqdF-4tzcC:
15.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_A_EF2A501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yizA-4tzcC:
19.9		 5yizA-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_B_EF2B501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yizb-4tzcC:
21.1		 5yizb-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_D_EF2D501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yizD-4tzcC:
19.8		 5yizD-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_E_EF2E501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 5yize-4tzcC:
20.4		 5yize-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yizG-4tzcC:
19.9
5yizY-4tzcC:
20.3		 5yizG-4tzcC:
97.50
5yizY-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_H_EF2H501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.12A 5yizh-4tzcC:
20.9		 5yizh-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_J_EF2J501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yizJ-4tzcC:
20.8		 5yizJ-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.22A 5yizk-4tzcC:
20.3
5yizt-4tzcC:
19.8		 5yizk-4tzcC:
97.50
5yizt-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_M_EF2M501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.24A 5yizM-4tzcC:
20.4		 5yizM-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_N_EF2N501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yizn-4tzcC:
20.8		 5yizn-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_P_EF2P501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.10A 5yizP-4tzcC:
21.1		 5yizP-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_Q_EF2Q501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.12A 5yizq-4tzcC:
21.0		 5yizq-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_S_EF2S501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.12A 5yizS-4tzcC:
21.1		 5yizS-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yizk-4tzcC:
20.3
5yizt-4tzcC:
19.8		 5yizk-4tzcC:
97.50
5yizt-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_V_EF2V501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yizV-4tzcC:
21.0		 5yizV-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yizG-4tzcC:
19.9
5yizY-4tzcC:
20.3		 5yizG-4tzcC:
97.50
5yizY-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_A_EF2A501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj0A-4tzcC:
19.9		 5yj0A-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_B_EF2B501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.12A 5yj0b-4tzcC:
21.1		 5yj0b-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_D_EF2D501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj0D-4tzcC:
19.8		 5yj0D-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_E_EF2E501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yj0e-4tzcC:
20.4		 5yj0e-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj0G-4tzcC:
19.9
5yj0Y-4tzcC:
20.3		 5yj0G-4tzcC:
97.50
5yj0Y-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_H_EF2H501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.12A 5yj0h-4tzcC:
20.8		 5yj0h-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_J_EF2J501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yj0J-4tzcC:
20.8		 5yj0J-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yj0k-4tzcC:
20.2
5yj0t-4tzcC:
19.7		 5yj0k-4tzcC:
97.50
5yj0t-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_M_EF2M501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yj0M-4tzcC:
20.3		 5yj0M-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_N_EF2N501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj0n-4tzcC:
20.7		 5yj0n-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_P_EF2P501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.10A 5yj0P-4tzcC:
21.1		 5yj0P-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_Q_EF2Q501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.10A 5yj0q-4tzcC:
21.0		 5yj0q-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_S_EF2S501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.11A 5yj0S-4tzcC:
21.0		 5yj0S-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yj0k-4tzcC:
20.2
5yj0t-4tzcC:
19.7		 5yj0k-4tzcC:
97.50
5yj0t-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_V_EF2V501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yj0V-4tzcC:
21.0		 5yj0V-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yj0G-4tzcC:
19.9
5yj0Y-4tzcC:
20.3		 5yj0G-4tzcC:
97.50
5yj0Y-4tzcC:
97.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_A_6ELA501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.18A 5yj1A-4tzcC:
19.8		 5yj1A-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_B_6ELB501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yj1b-4tzcC:
20.9		 5yj1b-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_D_6ELD501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.18A 5yj1D-4tzcC:
19.8		 5yj1D-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_E_6ELE501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 5yj1e-4tzcC:
20.5		 5yj1e-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 8 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yj1G-4tzcC:
19.6
5yj1Y-4tzcC:
20.5		 5yj1G-4tzcC:
98.17
5yj1Y-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_H_6ELH501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yj1h-4tzcC:
20.8		 5yj1h-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_J_6ELJ501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj1J-4tzcC:
20.7		 5yj1J-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.26A 5yj1k-4tzcC:
20.1
5yj1t-4tzcC:
19.7		 5yj1k-4tzcC:
98.17
5yj1t-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_M_6ELM501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.24A 5yj1M-4tzcC:
20.5		 5yj1M-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_N_6ELN501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj1n-4tzcC:
20.6		 5yj1n-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_P_6ELP501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.13A 5yj1P-4tzcC:
20.9		 5yj1P-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_Q_6ELQ501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.18A 5yj1q-4tzcC:
20.9		 5yj1q-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_S_6ELS501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.14A 5yj1S-4tzcC:
20.9		 5yj1S-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 8 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.21A 5yj1k-4tzcC:
20.1
5yj1t-4tzcC:
19.7		 5yj1k-4tzcC:
98.17
5yj1t-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_V_6ELV501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 5 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.15A 5yj1V-4tzcC:
20.8		 5yj1V-4tzcC:
98.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 7 HIS C 380
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.23A 5yj1G-4tzcC:
19.6
5yj1Y-4tzcC:
20.5		 5yj1G-4tzcC:
98.17
5yj1Y-4tzcC:
98.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 12 HIS C 380
SER C 381
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 ( 4.9A)
EF2  C 502 (-4.1A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.89A 6h0gE-4tzcC:
9.2
6h0gF-4tzcC:
undetectable		 6h0gE-4tzcC:
17.43
6h0gF-4tzcC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 4tzc PROTEIN CEREBLON
(Mus
musculus) 		5 / 12 SER C 381
TRP C 382
TRP C 388
TRP C 402
PHE C 404
 EF2  C 502 (-4.1A)
EF2  C 502 ( 3.2A)
EF2  C 502 (-3.5A)
EF2  C 502 (-3.8A)
EF2  C 502 (-4.5A)
 0.27A 6h0gE-4tzcC:
9.2
6h0gF-4tzcC:
undetectable		 6h0gE-4tzcC:
17.43
6h0gF-4tzcC:
20.73