SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EDJ'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MUO_A_ADNA1_1 (AURORA-RELATEDKINASE 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 9 | LEU A 22GLY A 23VAL A 30ALA A 43TYR A 95LEU A 146 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.8A)EDJ A 301 ( 4.5A) | 0.67A | 1muoA-6bx6A:20.7 | 1muoA-6bx6A:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_B_MIXB1539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 7 / 12 | LEU A 22GLY A 23VAL A 30ALA A 43MET A 93TYR A 95VAL A 96 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A) | 0.66A | 2fumB-6bx6A:22.4 | 2fumB-6bx6A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_C_MIXC2539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 12 | LEU A 22ALA A 43MET A 93TYR A 95VAL A 96ASN A 144 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A)None | 0.78A | 2fumC-6bx6A:22.4 | 2fumC-6bx6A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_C_MIXC2539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 12 | LEU A 22GLY A 23VAL A 30ALA A 43TYR A 95VAL A 96 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A) | 0.63A | 2fumC-6bx6A:22.4 | 2fumC-6bx6A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_C_MIXC2539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 12 | LEU A 22VAL A 30ALA A 43MET A 93TYR A 95VAL A 96 | EDJ A 301 (-3.9A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A) | 0.71A | 2fumC-6bx6A:22.4 | 2fumC-6bx6A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FUP_A_MI1A1_1 (TYROSINE-PROTEINKINASE JAK2) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 8 / 12 | LEU A 22GLY A 23GLY A 25GLY A 28VAL A 30ALA A 43MET A 93TYR A 95 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneNoneNoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A) | 0.64A | 3fupA-6bx6A:18.4 | 3fupA-6bx6A:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0F_A_B49A9001_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 11 | LEU A 22VAL A 30ALA A 43TYR A 95GLY A 99LEU A 146 | EDJ A 301 (-3.9A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.8A)EDJ A 301 ( 3.7A)EDJ A 301 ( 4.5A) | 0.53A | 3g0fA-6bx6A:18.8 | 3g0fA-6bx6A:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LXN_A_MI1A1_1 (NON-RECEPTORTYROSINE-PROTEINKINASE TYK2) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 7 / 12 | LEU A 22GLY A 23GLY A 25ALA A 43ILE A 77TYR A 95VAL A 96 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A) | 0.63A | 3lxnA-6bx6A:18.9 | 3lxnA-6bx6A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LXN_A_MI1A1_1 (NON-RECEPTORTYROSINE-PROTEINKINASE TYK2) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 7 / 12 | LEU A 22GLY A 23GLY A 25VAL A 30ALA A 43ILE A 77TYR A 95 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneNoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)EDJ A 301 ( 4.8A) | 0.61A | 3lxnA-6bx6A:18.9 | 3lxnA-6bx6A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_A_0LIA1000_2 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 5 / 9 | ILE A 76ILE A 77MET A 91TYR A 95ILE A 155 | NoneEDJ A 301 ( 4.7A)NoneEDJ A 301 ( 4.8A)None | 0.52A | 3zosA-6bx6A:18.8 | 3zosA-6bx6A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_B_0LIB1000_2 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 5 / 9 | LEU A 22ILE A 76MET A 91TYR A 95ILE A 155 | EDJ A 301 (-3.9A)NoneNoneEDJ A 301 ( 4.8A)None | 0.45A | 3zosB-6bx6A:18.8 | 3zosB-6bx6A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 7 / 12 | VAL A 30ALA A 43ILE A 77MET A 91TYR A 95LEU A 146ALA A 156 | NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)NoneEDJ A 301 ( 4.8A)EDJ A 301 ( 4.5A)EDJ A 301 (-3.2A) | 1.12A | 4bkjA-6bx6A:18.7 | 4bkjA-6bx6A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 12 | VAL A 30ALA A 43ILE A 77MET A 91LEU A 146ALA A 156 | NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)NoneEDJ A 301 ( 4.5A)EDJ A 301 (-3.2A) | 1.07A | 4bkjB-6bx6A:18.6 | 4bkjB-6bx6A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_A_0LIA1000_2 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 4 / 5 | VAL A 30ILE A 76TYR A 95ILE A 155 | NoneNoneEDJ A 301 ( 4.8A)None | 0.71A | 4c8bA-6bx6A:19.9 | 4c8bA-6bx6A:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMZ_A_B49A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 12 | GLY A 23VAL A 30ALA A 43MET A 93TYR A 95LEU A 146 | EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A)EDJ A 301 ( 4.5A) | 0.74A | 4qmzA-6bx6A:14.1 | 4qmzA-6bx6A:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TYJ_A_0LIA801_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 4 / 6 | LEU A 22VAL A 30ILE A 76ILE A 155 | EDJ A 301 (-3.9A)NoneNoneNone | 0.72A | 4tyjA-6bx6A:19.2 | 4tyjA-6bx6A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V04_B_0LIB1771_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 10 | LEU A 22VAL A 30ILE A 77TYR A 95LEU A 146ILE A 155 | EDJ A 301 (-3.9A)NoneEDJ A 301 ( 4.7A)EDJ A 301 ( 4.8A)EDJ A 301 ( 4.5A)None | 0.73A | 4v04B-6bx6A:19.4 | 4v04B-6bx6A:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_C_ANWC601_0 (RHODOPSIN KINASE) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 4 / 6 | LEU A 22ALA A 43MET A 93LEU A 146 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.5A) | 0.71A | 4wboC-6bx6A:21.2 | 4wboC-6bx6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_B_ADNB401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 5 / 9 | GLY A 23VAL A 30ALA A 43ILE A 77MET A 93 | EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)EDJ A 301 ( 4.2A) | 0.72A | 5lw1B-6bx6A:14.3 | 5lw1B-6bx6A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_E_ADNE401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 5 / 10 | GLY A 23VAL A 30ALA A 43ILE A 77MET A 93 | EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.7A)EDJ A 301 ( 4.2A) | 0.77A | 5lw1E-6bx6A:16.4 | 5lw1E-6bx6A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N3H_A_NCAA401_0 (CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 10 | LEU A 22VAL A 30ALA A 43MET A 93TYR A 95VAL A 96 | EDJ A 301 (-3.9A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.2A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A) | 0.46A | 5n3hA-6bx6A:23.8 | 5n3hA-6bx6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N3H_A_NCAA401_0 (CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 6 / 10 | LEU A 22VAL A 30ALA A 43TYR A 95VAL A 96LEU A 146 | EDJ A 301 (-3.9A)NoneEDJ A 301 (-3.4A)EDJ A 301 ( 4.8A)EDJ A 301 (-3.7A)EDJ A 301 ( 4.5A) | 0.68A | 5n3hA-6bx6A:23.8 | 5n3hA-6bx6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XV7_A_EMHA705_1 (SERINE-ARGININE (SR)PROTEIN KINASE 1) |
6bx6 | 5'-AMP-ACTIVATEDPROTEIN KINASECATALYTIC SUBUNITALPHA-2 (Homosapiens) | 5 / 12 | LEU A 22GLY A 23VAL A 30ALA A 43ALA A 156 | EDJ A 301 (-3.9A)EDJ A 301 (-3.4A)NoneEDJ A 301 (-3.4A)EDJ A 301 (-3.2A) | 0.55A | 5xv7A-6bx6A:18.6 | 5xv7A-6bx6A:26.67 |