SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EDG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 6f1j -
(-) 		5 / 10 PHE A 174
ALA A 103
PHE A 126
LEU A 146
THR A 105
 None
EDG  A 401 (-3.6A)
None
None
None
 1.21A 3a3yA-6f1jA:
undetectable		 3a3yA-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 6f1j -
(-) 		4 / 5 ARG A  51
ASP A 160
ASP A 177
ARG A 237
 EDG  A 401 (-4.4A)
EDG  A 401 (-2.9A)
None
PEG  A 403 (-4.6A)
 1.25A 3naiC-6f1jA:
undetectable		 3naiC-6f1jA:
undetectable