SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ED9'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1D4F_B_ADNB602_1 (S-ADENOSYLHOMOCYSTEINE HYDROLASE) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 12 | LEU A 404HIS A 305GLU A 220HIS A 397LEU A 309 | NoneED9 A 501 (-3.9A)NoneED9 A 501 (-3.9A)ED9 A 501 (-4.9A) | 1.34A | 1d4fB-3wgpA:undetectable | 1d4fB-3wgpA:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DB1_A_VDXA428_1 (VITAMIN D NUCLEARRECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 12 | LEU A 233SER A 237SER A 278CYH A 288LEU A 393 | ED9 A 501 ( 4.3A)ED9 A 501 (-2.7A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)None | 1.27A | 1db1A-3wgpA:42.0 | 1db1A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DB1_A_VDXA428_1 (VITAMIN D NUCLEARRECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143LEU A 230LEU A 233VAL A 234SER A 237SER A 275SER A 278CYH A 288VAL A 300HIS A 305LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.6A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.19A | 1db1A-3wgpA:42.0 | 1db1A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DB1_A_VDXA428_2 (VITAMIN D NUCLEARRECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 6 / 6 | LEU A 227ILE A 271ARG A 274TRP A 286TYR A 295VAL A 418 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.5A)NoneNone | 0.14A | 1db1A-3wgpA:42.0 | 1db1A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143LEU A 230LEU A 233VAL A 234SER A 237SER A 275SER A 278CYH A 288VAL A 300HIS A 305LEU A 313HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.6A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)NoneED9 A 501 (-3.9A) | 0.17A | 1ie9A-3wgpA:42.6 | 1ie9A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IE9_A_VDXA500_2 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 4 / 4 | LEU A 227ILE A 271ARG A 274TRP A 286 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.5A) | 0.30A | 1ie9A-3wgpA:42.6 | 1ie9A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1RK3_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 6 / 12 | LEU A 233SER A 237SER A 278TRP A 286CYH A 288LEU A 393 | ED9 A 501 ( 4.3A)ED9 A 501 (-2.7A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)None | 1.38A | 1rk3A-3wgpA:38.8 | 1rk3A-3wgpA:89.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1RK3_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143LEU A 233VAL A 234SER A 237SER A 275SER A 278TRP A 286CYH A 288VAL A 300HIS A 305LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.21A | 1rk3A-3wgpA:38.8 | 1rk3A-3wgpA:89.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1RK3_A_VDXA500_2 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 4 / 4 | LEU A 227ILE A 271ARG A 274TYR A 401 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)None | 0.37A | 1rk3A-3wgpA:38.8 | 1rk3A-3wgpA:89.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S19_A_MC9A500_0 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | LEU A 227LEU A 233VAL A 234ILE A 271SER A 275SER A 278TRP A 286CYH A 288TYR A 295VAL A 300LEU A 309LEU A 313 | NoneED9 A 501 ( 4.3A)NoneED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)NoneED9 A 501 (-4.5A)ED9 A 501 (-4.9A)None | 0.16A | 1s19A-3wgpA:42.0 | 1s19A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1S19_A_MC9A500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 5 | TYR A 143SER A 237ARG A 274HIS A 305HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 (-2.7A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-3.9A) | 0.13A | 1s19A-3wgpA:42.0 | 1s19A-3wgpA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 12 | PHE A 150SER A 237SER A 278CYH A 288LEU A 393 | NoneED9 A 501 (-2.7A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)None | 1.28A | 2hc4A-3wgpA:37.7 | 2hc4A-3wgpA:64.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 7 / 12 | PHE A 153LEU A 233VAL A 234SER A 237HIS A 305LEU A 309HIS A 397 | NoneED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 1.43A | 2hc4A-3wgpA:37.7 | 2hc4A-3wgpA:64.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143PHE A 150LEU A 233VAL A 234SER A 237SER A 278CYH A 288VAL A 300HIS A 305LEU A 309HIS A 397LEU A 404 | ED9 A 501 (-3.7A)NoneED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A)None | 0.28A | 2hc4A-3wgpA:37.7 | 2hc4A-3wgpA:64.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 7 / 7 | LEU A 227LEU A 230ILE A 271ARG A 274SER A 275TRP A 286TYR A 401 | NoneED9 A 501 ( 4.6A)ED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-3.5A)None | 0.39A | 2hc4A-3wgpA:37.7 | 2hc4A-3wgpA:64.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 4 / 7 | LEU A 414ILE A 271ARG A 274SER A 275 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A) | 1.22A | 2hc4A-3wgpA:37.7 | 2hc4A-3wgpA:64.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ZLC_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143LEU A 233VAL A 234SER A 237SER A 275SER A 278CYH A 288VAL A 300HIS A 305LEU A 309HIS A 397LEU A 404 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A)None | 0.25A | 2zlcA-3wgpA:38.7 | 2zlcA-3wgpA:90.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ZLC_A_VDXA500_2 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 5 | LEU A 227ILE A 271ARG A 274TRP A 286TYR A 401 | NoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.5A)None | 0.36A | 2zlcA-3wgpA:38.7 | 2zlcA-3wgpA:90.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 5 / 12 | LEU A 230VAL A 234SER A 237VAL A 300LEU A 313 | ED9 A 501 ( 4.6A)NoneED9 A 501 (-2.7A)ED9 A 501 (-4.5A)None | 1.16A | 3m7rA-3wgpA:42.6 | 3m7rA-3wgpA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 10 / 12 | TYR A 143LEU A 230LEU A 233VAL A 234SER A 275SER A 278CYH A 288VAL A 300LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.6A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.20A | 3m7rA-3wgpA:42.6 | 3m7rA-3wgpA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 10 / 12 | TYR A 143LEU A 230VAL A 234SER A 237SER A 275SER A 278CYH A 288VAL A 300LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.6A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.56A | 3m7rA-3wgpA:42.6 | 3m7rA-3wgpA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3M7R_A_VDXA425_2 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 9 / 9 | PHE A 150LEU A 227ILE A 271ARG A 274TRP A 286TYR A 295LEU A 313TYR A 401VAL A 418 | NoneNoneED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.5A)NoneNoneNoneNone | 0.17A | 3m7rA-3wgpA:42.6 | 3m7rA-3wgpA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3VT3_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 6 / 12 | LEU A 233SER A 237SER A 278TRP A 286CYH A 288LEU A 393 | ED9 A 501 ( 4.3A)ED9 A 501 (-2.7A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)None | 1.39A | 3vt3A-3wgpA:38.3 | 3vt3A-3wgpA:90.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3VT3_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143LEU A 233VAL A 234SER A 237SER A 275SER A 278TRP A 286CYH A 288VAL A 300HIS A 305LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.21A | 3vt3A-3wgpA:38.3 | 3vt3A-3wgpA:90.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3VT7_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 11 / 12 | TYR A 143LEU A 233VAL A 234SER A 237ARG A 274SER A 275SER A 278VAL A 300HIS A 305LEU A 309HIS A 397 | ED9 A 501 (-3.7A)ED9 A 501 ( 4.3A)NoneED9 A 501 (-2.7A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.21A | 3vt7A-3wgpA:36.6 | 3vt7A-3wgpA:90.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3VT7_A_VDXA500_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 11 / 12 | TYR A 143TYR A 147VAL A 234SER A 237ARG A 274SER A 275SER A 278VAL A 300HIS A 305LEU A 309HIS A 397 | ED9 A 501 (-3.7A)NoneNoneED9 A 501 (-2.7A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-4.9A)ED9 A 501 (-3.9A) | 0.60A | 3vt7A-3wgpA:36.6 | 3vt7A-3wgpA:90.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3VT7_A_VDXA500_2 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 4 / 4 | LEU A 227ILE A 271TYR A 295TYR A 401 | NoneED9 A 501 (-4.5A)NoneNone | 0.39A | 3vt7A-3wgpA:36.6 | 3vt7A-3wgpA:90.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RUJ_A_VDXA501_1 (VITAMIN D3 RECEPTORA) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143VAL A 234SER A 237ILE A 271ARG A 274SER A 275SER A 278TRP A 286CYH A 288VAL A 300HIS A 305HIS A 397 | ED9 A 501 (-3.7A)NoneED9 A 501 (-2.7A)ED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.4A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-3.9A) | 0.26A | 4rujA-3wgpA:37.4 | 4rujA-3wgpA:64.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5H1E_A_VDXA501_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 7 / 12 | PHE A 153LEU A 233SER A 237ILE A 271ARG A 274HIS A 305HIS A 397 | NoneED9 A 501 ( 4.3A)ED9 A 501 (-2.7A)ED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-3.9A) | 1.37A | 5h1eA-3wgpA:37.4 | 5h1eA-3wgpA:90.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5H1E_A_VDXA501_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 12 / 12 | TYR A 143PHE A 150LEU A 233SER A 237ILE A 271ARG A 274SER A 275SER A 278TRP A 286VAL A 300HIS A 305HIS A 397 | ED9 A 501 (-3.7A)NoneED9 A 501 ( 4.3A)ED9 A 501 (-2.7A)ED9 A 501 (-4.5A)ED9 A 501 (-2.9A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-4.5A)ED9 A 501 (-3.9A)ED9 A 501 (-3.9A) | 0.32A | 5h1eA-3wgpA:37.4 | 5h1eA-3wgpA:90.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5H1E_A_VDXA501_1 (VITAMIN D3 RECEPTOR) |
3wgp | VITAMIN D3 RECEPTOR (Homosapiens) | 7 / 12 | TYR A 143PHE A 150LEU A 233SER A 275SER A 278TRP A 286HIS A 305 | ED9 A 501 (-3.7A)NoneED9 A 501 ( 4.3A)ED9 A 501 (-3.9A)ED9 A 501 (-2.7A)ED9 A 501 (-3.5A)ED9 A 501 (-3.9A) | 1.19A | 5h1eA-3wgpA:37.4 | 5h1eA-3wgpA:90.51 |