SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ECV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 848
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.68A 1a28A-5mwpA:
36.4		 1a28A-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.42A 1a28A-5mwpA:
36.4		 1a28A-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ASN A 770
LEU A 772
LEU A 938
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 ( 4.3A)
ECV  A1101 ( 4.7A)
 1.16A 1a28A-5mwpA:
36.4		 1a28A-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.09A 1a28A-5mwpA:
36.4		 1a28A-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 848
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.81A 1a28B-5mwpA:
36.5		 1a28B-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.39A 1a28B-5mwpA:
36.5		 1a28B-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.16A 1a28B-5mwpA:
36.5		 1a28B-5mwpA:
46.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 769
LEU A 772
ALA A 773
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.55A 1g50A-5mwpA:
27.3		 1g50A-5mwpA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
MET A 845
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 0.75A 1gs4A-5mwpA:
37.0		 1gs4A-5mwpA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
LEU A 772
ALA A 773
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.31A 1gwrA-5mwpA:
25.0		 1gwrA-5mwpA:
16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
THR A 945
PHE A 956
LEU A 960
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
None
 0.52A 1m2zA-5mwpA:
35.2		 1m2zA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
CYH A 942
THR A 945
PHE A 956
LEU A 960
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
None
 1.10A 1m2zA-5mwpA:
35.2		 1m2zA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.27A 1m2zA-5mwpA:
35.2		 1m2zA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 942
THR A 945
PHE A 956
LEU A 960
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
None
 0.48A 1m2zD-5mwpA:
35.0		 1m2zD-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLY A 774
GLN A 776
CYH A 942
THR A 945
PHE A 956
LEU A 960
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
None
 1.12A 1m2zD-5mwpA:
35.0		 1m2zD-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLN A 776
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.34A 1nhzA-5mwpA:
28.8		 1nhzA-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
LEU A 814
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.30A 1nhzA-5mwpA:
28.8		 1nhzA-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
GLN A 776
LEU A 814
ARG A 817
LEU A 938
 ECV  A1101 (-4.7A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
 0.51A 1nhzA-5mwpA:
28.8		 1nhzA-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
THR A 945
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.71A 1p93A-5mwpA:
34.0		 1p93A-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.36A 1p93A-5mwpA:
34.0		 1p93A-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.50A 1p93B-5mwpA:
34.3		 1p93B-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.97A 1p93B-5mwpA:
34.3		 1p93B-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.27A 1p93B-5mwpA:
34.3		 1p93B-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.54A 1p93C-5mwpA:
33.8		 1p93C-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
MET A 807
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.21A 1p93C-5mwpA:
33.8		 1p93C-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.40A 1p93C-5mwpA:
33.8		 1p93C-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
PHE A 829
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.67A 1p93D-5mwpA:
33.9		 1p93D-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.98A 1p93D-5mwpA:
33.9		 1p93D-5mwpA:
41.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.32A 1qknA-5mwpA:
24.6		 1qknA-5mwpA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.40A 1qktA-5mwpA:
23.8		 1qktA-5mwpA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
LEU A 769
ALA A 773
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.56A 1s9pA-5mwpA:
26.9		 1s9pA-5mwpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
LEU A 772
ALA A 773
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.62A 1s9pB-5mwpA:
27.2		 1s9pB-5mwpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
LEU A 772
ALA A 773
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.56A 1s9pC-5mwpA:
27.0		 1s9pC-5mwpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
LEU A 769
ALA A 773
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.50A 1s9pD-5mwpA:
28.7		 1s9pD-5mwpA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
MET A 807
LEU A 848
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.6A)
None
ECV  A1101 (-4.0A)
 0.93A 1sqnA-5mwpA:
36.2		 1sqnA-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.48A 1sqnA-5mwpA:
36.2		 1sqnA-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
GLN A 776
MET A 807
LEU A 848
LEU A 938
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
None
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.85A 1sqnB-5mwpA:
36.8		 1sqnB-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 938
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.41A 1sqnB-5mwpA:
36.8		 1sqnB-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
LEU A 827
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-4.1A)
None
 1.13A 1sqnB-5mwpA:
36.8		 1sqnB-5mwpA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 765
LEU A 772
GLN A 776
LEU A 814
ARG A 817
 None
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 1.11A 1ya3A-5mwpA:
38.0		 1ya3A-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.41A 1ya3A-5mwpA:
38.0		 1ya3A-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.32A 1ya3A-5mwpA:
38.0		 1ya3A-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 (-4.0A)
 0.77A 1ya3A-5mwpA:
38.0		 1ya3A-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
SER A 811
LEU A 814
ARG A 817
MET A 845
LEU A 938
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.0A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.52A 1ya3B-5mwpA:
38.3		 1ya3B-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.26A 1ya3B-5mwpA:
38.3		 1ya3B-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
MET A 807
SER A 810
LEU A 814
ARG A 817
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.48A 1ya3B-5mwpA:
38.3		 1ya3B-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
MET A 845
LEU A 938
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.54A 1ya3C-5mwpA:
38.1		 1ya3C-5mwpA:
73.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
 0.64A 1z95A-5mwpA:
36.9		 1z95A-5mwpA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 10 LEU A 766
ASN A 770
GLN A 776
LEU A 814
ARG A 817
LEU A 848
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.76A 1zucA-5mwpA:
36.5		 1zucA-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 848
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.71A 1zucB-5mwpA:
36.4		 1zucB-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.44A 1zucB-5mwpA:
36.4		 1zucB-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 827
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.29A 1zucB-5mwpA:
36.4		 1zucB-5mwpA:
46.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
SER A 810
LEU A 814
ARG A 817
MET A 845
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.47A 2aa5A-5mwpA:
39.7		 2aa5A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 772
ALA A 773
GLN A 776
MET A 807
SER A 810
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 0.76A 2aa5A-5mwpA:
39.7		 2aa5A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 765
LEU A 772
GLN A 776
LEU A 814
ARG A 817
 None
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 1.29A 2aa5B-5mwpA:
39.3		 2aa5B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
SER A 810
LEU A 814
ARG A 817
MET A 845
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.50A 2aa5B-5mwpA:
39.3		 2aa5B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.33A 2aa5B-5mwpA:
39.3		 2aa5B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
CYH A 942
THR A 945
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.33A 2aa6A-5mwpA:
39.4		 2aa6A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ASN A 770
LEU A 827
CYH A 942
THR A 945
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.39A 2aa6A-5mwpA:
39.4		 2aa6A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 (-4.0A)
 0.68A 2aa6A-5mwpA:
39.4		 2aa6A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.36A 2aa6B-5mwpA:
39.3		 2aa6B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.69A 2aa6B-5mwpA:
39.3		 2aa6B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 852
CYH A 942
 ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-3.7A)
ECV  A1101 (-4.0A)
 0.75A 2ab2A-5mwpA:
39.4		 2ab2A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 845
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.38A 2ab2A-5mwpA:
39.4		 2ab2A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 6 LEU A 769
LEU A 772
LEU A 814
CYH A 849
LEU A 938
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-3.8A)
ECV  A1101 ( 4.3A)
 0.20A 2ab2A-5mwpA:
39.4		 2ab2A-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 852
CYH A 942
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-3.7A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.70A 2ab2B-5mwpA:
39.3		 2ab2B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 845
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.38A 2ab2B-5mwpA:
39.3		 2ab2B-5mwpA:
72.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
LEU A 772
LEU A 814
CYH A 849
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-3.8A)
 0.21A 2ab2B-5mwpA:
39.3		 2ab2B-5mwpA:
72.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
LEU A 772
TRP A 806
MET A 807
ARG A 817
MET A 845
LEU A 938
 ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
 0.72A 2am9A-5mwpA:
37.1		 2am9A-5mwpA:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 765
LEU A 772
GLN A 776
LEU A 814
ARG A 817
 None
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 1.20A 2oaxA-5mwpA:
38.4		 2oaxA-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.51A 2oaxA-5mwpA:
38.4		 2oaxA-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.18A 2oaxA-5mwpA:
38.4		 2oaxA-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
ALA A 773
TRP A 806
MET A 852
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
None
ECV  A1101 (-3.7A)
 0.64A 2oaxA-5mwpA:
38.4		 2oaxA-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 765
LEU A 772
GLN A 776
LEU A 814
ARG A 817
 None
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 1.17A 2oaxB-5mwpA:
38.3		 2oaxB-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.40A 2oaxB-5mwpA:
38.3		 2oaxB-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 1.28A 2oaxB-5mwpA:
38.3		 2oaxB-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.47A 2oaxC-5mwpA:
37.9		 2oaxC-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.25A 2oaxC-5mwpA:
37.9		 2oaxC-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 ( 4.7A)
 0.43A 2oaxD-5mwpA:
38.6		 2oaxD-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
MET A 852
CYH A 942
THR A 945
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.7A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.80A 2oaxD-5mwpA:
38.6		 2oaxD-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
CYH A 942
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 0.58A 2oaxE-5mwpA:
38.1		 2oaxE-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 1.36A 2oaxE-5mwpA:
38.1		 2oaxE-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.50A 2oaxF-5mwpA:
37.8		 2oaxF-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
LEU A 827
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.15A 2oaxF-5mwpA:
37.8		 2oaxF-5mwpA:
73.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 766
LEU A 769
MET A 845
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 0.77A 2oaxF-5mwpA:
37.8		 2oaxF-5mwpA:
73.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
ARG A 817
MET A 845
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 0.66A 2oz7A-5mwpA:
35.8		 2oz7A-5mwpA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 TRP A 806
MET A 807
MET A 852
LEU A 938
 None
ECV  A1101 (-3.6A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.31A 2oz7A-5mwpA:
35.7		 2oz7A-5mwpA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.58A 2q7iA-5mwpA:
37.4		 2q7iA-5mwpA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.67A 2q7jA-5mwpA:
37.4		 2q7jA-5mwpA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 845
LEU A 938
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
 0.64A 2q7kA-5mwpA:
37.3		 2q7kA-5mwpA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
ARG A 817
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
 1.44A 2q7lA-5mwpA:
37.2		 2q7lA-5mwpA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.59A 2q7lA-5mwpA:
37.2		 2q7lA-5mwpA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
GLN A 776
TRP A 806
MET A 807
ARG A 817
LEU A 848
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-4.0A)
 0.95A 2w8yA-5mwpA:
36.4		 2w8yA-5mwpA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.61A 2w8yA-5mwpA:
36.4		 2w8yA-5mwpA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.49A 2w8yB-5mwpA:
36.4		 2w8yB-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.12A 2w8yB-5mwpA:
36.4		 2w8yB-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.66A 2yhdA-5mwpA:
37.1		 2yhdA-5mwpA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
LEU A 772
MET A 807
ARG A 817
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 0.60A 2yloA-5mwpA:
37.0		 2yloA-5mwpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 11 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
LEU A 938
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
 0.69A 2ylpA-5mwpA:
37.3		 2ylpA-5mwpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 11 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.65A 2ylqA-5mwpA:
37.2		 2ylqA-5mwpA:
19.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.49A 3cldA-5mwpA:
35.1		 3cldA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.18A 3cldA-5mwpA:
35.1		 3cldA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.54A 3cldB-5mwpA:
35.2		 3cldB-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.86A 3cldB-5mwpA:
35.2		 3cldB-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 848
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-4.0A)
 0.89A 3d90A-5mwpA:
35.7		 3d90A-5mwpA:
38.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.56A 3d90A-5mwpA:
35.7		 3d90A-5mwpA:
38.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.11A 3d90A-5mwpA:
35.7		 3d90A-5mwpA:
38.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 848
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
None
ECV  A1101 (-4.0A)
 0.78A 3d90B-5mwpA:
36.0		 3d90B-5mwpA:
38.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.59A 3d90B-5mwpA:
36.0		 3d90B-5mwpA:
38.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.33A 3d90B-5mwpA:
36.0		 3d90B-5mwpA:
38.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.52A 3erdA-5mwpA:
27.4		 3erdA-5mwpA:
13.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
CYH A 942
THR A 945
VAL A 954
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
None
 1.15A 3gn8A-5mwpA:
36.1		 3gn8A-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.24A 3gn8A-5mwpA:
36.1		 3gn8A-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
THR A 945
VAL A 954
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
None
 0.41A 3gn8A-5mwpA:
36.1		 3gn8A-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
CYH A 942
THR A 945
VAL A 954
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
None
ECV  A1101 ( 4.7A)
 1.07A 3gn8B-5mwpA:
35.9		 3gn8B-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.21A 3gn8B-5mwpA:
35.9		 3gn8B-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
THR A 945
VAL A 954
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
None
ECV  A1101 ( 4.7A)
 0.40A 3gn8B-5mwpA:
35.9		 3gn8B-5mwpA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.35A 3h52A-5mwpA:
24.6		 3h52A-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
 0.73A 3h52A-5mwpA:
24.6		 3h52A-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 772
TRP A 806
MET A 807
MET A 959
LEU A 960
 ECV  A1101 ( 3.9A)
None
ECV  A1101 (-3.6A)
None
None
 1.22A 3h52B-5mwpA:
26.6		 3h52B-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
LEU A 814
ARG A 817
CYH A 849
ILE A 964
 ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
None
 1.07A 3h52B-5mwpA:
26.6		 3h52B-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 GLY A 774
GLN A 776
LEU A 814
ARG A 817
CYH A 849
CYH A 942
ILE A 963
 None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.0A)
None
 0.92A 3h52B-5mwpA:
26.6		 3h52B-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.22A 3h52C-5mwpA:
25.2		 3h52C-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
PHE A 829
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
 0.61A 3h52C-5mwpA:
25.2		 3h52C-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.79A 3h52D-5mwpA:
26.2		 3h52D-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.33A 3h52D-5mwpA:
26.2		 3h52D-5mwpA:
53.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 814
ARG A 817
MET A 845
MET A 852
LEU A 934
 ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
None
 1.32A 3h52D-5mwpA:
26.2		 3h52D-5mwpA:
53.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.48A 3hm1A-5mwpA:
28.3		 3hm1A-5mwpA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 769
LEU A 772
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.41A 3hm1B-5mwpA:
28.0		 3hm1B-5mwpA:
14.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
LEU A 938
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.46A 3mneA-5mwpA:
34.0		 3mneA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.28A 3mneA-5mwpA:
34.0		 3mneA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.37A 3mneA-5mwpA:
34.0		 3mneA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.48A 3mnoA-5mwpA:
34.5		 3mnoA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
MET A 807
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.20A 3mnoA-5mwpA:
34.5		 3mnoA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.49A 3mnpA-5mwpA:
35.1		 3mnpA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
MET A 807
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.22A 3mnpA-5mwpA:
35.1		 3mnpA-5mwpA:
47.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
LEU A 772
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.38A 3ollA-5mwpA:
27.5		 3ollA-5mwpA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
ALA A 773
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.33A 3olsA-5mwpA:
28.2		 3olsA-5mwpA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.34A 3olsB-5mwpA:
27.5		 3olsB-5mwpA:
14.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 845
LEU A 938
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.36A 3vhuA-5mwpA:
39.5		 3vhuA-5mwpA:
66.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.26A 3vhuA-5mwpA:
39.5		 3vhuA-5mwpA:
66.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
LEU A 772
SER A 811
MET A 852
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.0A)
ECV  A1101 (-3.7A)
 0.97A 3vhuA-5mwpA:
39.5		 3vhuA-5mwpA:
66.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
MET A 807
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.61A 3zqtA-5mwpA:
37.2		 3zqtA-5mwpA:
19.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
MET A 845
CYH A 942
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.46A 4fn9A-5mwpA:
37.6		 4fn9A-5mwpA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 845
THR A 945
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.49A 4fn9B-5mwpA:
37.6		 4fn9B-5mwpA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
ARG A 817
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
 1.50A 4hlwA-5mwpA:
37.3		 4hlwA-5mwpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.66A 4hlwA-5mwpA:
37.3		 4hlwA-5mwpA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.38A 4j24A-5mwpA:
28.3		 4j24A-5mwpA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.31A 4j24D-5mwpA:
28.0		 4j24D-5mwpA:
14.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 9 LEU A 766
ALA A 844
LEU A 848
PHE A 941
TYR A 944
THR A 945
LEU A 952
 ECV  A1101 ( 3.9A)
None
None
ECV  A1101 (-4.3A)
None
ECV  A1101 (-3.2A)
None
 0.47A 4ltwA-5mwpA:
38.0		 4ltwA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
MET A 845
LEU A 938
CYH A 942
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.44A 4ltwA-5mwpA:
38.0		 4ltwA-5mwpA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 8 TRP A 806
PHE A 941
THR A 945
VAL A 954
PHE A 956
 None
ECV  A1101 (-4.3A)
ECV  A1101 (-3.2A)
None
ECV  A1101 ( 4.7A)
 0.44A 4ltwA-5mwpA:
38.0		 4ltwA-5mwpA:
47.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 7 ASN A 770
MET A 852
LEU A 938
ILE A 963
ILE A 964
 ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
None
None
 0.76A 4ojbA-5mwpA:
36.8		 4ojbA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 7 LEU A 769
ASN A 770
ILE A 963
ILE A 964
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
None
None
 0.54A 4ojbA-5mwpA:
36.8		 4ojbA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
 0.75A 4ok1A-5mwpA:
36.3		 4ok1A-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 8 ASN A 770
MET A 852
LEU A 938
ILE A 963
 ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
None
 0.77A 4ok1A-5mwpA:
36.3		 4ok1A-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 8 LEU A 766
ASN A 770
LEU A 938
ILE A 963
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 4.3A)
None
 0.51A 4ok1A-5mwpA:
36.3		 4ok1A-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
 0.74A 4okbA-5mwpA:
36.7		 4okbA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 LEU A 769
ASN A 770
MET A 852
LEU A 938
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 0.94A 4okbA-5mwpA:
36.7		 4okbA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
ILE A 964
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
None
 0.92A 4oktA-5mwpA:
35.9		 4oktA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
None
 0.64A 4okwA-5mwpA:
36.8		 4okwA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 6 LEU A 769
ASN A 770
MET A 852
LEU A 938
ILE A 964
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
None
 0.87A 4okxA-5mwpA:
37.0		 4okxA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
 0.65A 4olmA-5mwpA:
36.1		 4olmA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 ASN A 770
MET A 852
ILE A 963
ILE A 964
 ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
None
None
 0.72A 4olmA-5mwpA:
36.1		 4olmA-5mwpA:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.24A 4p6xA-5mwpA:
34.9		 4p6xA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.56A 4p6xA-5mwpA:
34.9		 4p6xA-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 11 ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
 ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
 0.41A 4p6xC-5mwpA:
35.3		 4p6xC-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.49A 4p6xE-5mwpA:
34.6		 4p6xE-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.48A 4p6xG-5mwpA:
34.8		 4p6xG-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.02A 4p6xG-5mwpA:
34.8		 4p6xG-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.22A 4p6xG-5mwpA:
34.8		 4p6xG-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.29A 4p6xI-5mwpA:
34.9		 4p6xI-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.31A 4p6xI-5mwpA:
34.9		 4p6xI-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.57A 4p6xI-5mwpA:
34.9		 4p6xI-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.45A 4p6xK-5mwpA:
35.2		 4p6xK-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.04A 4p6xK-5mwpA:
35.2		 4p6xK-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.29A 4p6xK-5mwpA:
35.2		 4p6xK-5mwpA:
45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
ALA A 773
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.21A 4pxmA-5mwpA:
27.9		 4pxmA-5mwpA:
14.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ALA A 773
GLN A 776
MET A 807
SER A 810
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 0.93A 4udaA-5mwpA:
39.9		 4udaA-5mwpA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
SER A 810
ARG A 817
MET A 845
LEU A 938
CYH A 942
PHE A 956
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.7A)
 0.59A 4udaA-5mwpA:
39.9		 4udaA-5mwpA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.28A 4udcA-5mwpA:
35.0		 4udcA-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.24A 4udcA-5mwpA:
35.0		 4udcA-5mwpA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
PHE A 956
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.56A 4udcA-5mwpA:
35.0		 4udcA-5mwpA:
41.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.88A 4xi3C-5mwpA:
24.2		 4xi3C-5mwpA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
TRP A 806
LEU A 814
ARG A 817
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
None
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.58A 4xi3C-5mwpA:
24.2		 4xi3C-5mwpA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ALA A 773
LEU A 814
ARG A 817
MET A 845
LEU A 960
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
None
 0.62A 4zn7A-5mwpA:
27.5		 4zn7A-5mwpA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.84A 5gs4A-5mwpA:
26.7		 5gs4A-5mwpA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.74A 5gtrA-5mwpA:
26.2		 5gtrA-5mwpA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 772
ALA A 773
LEU A 814
ARG A 817
MET A 845
 ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-4.0A)
 0.49A 5hyrB-5mwpA:
26.9		 5hyrB-5mwpA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
ALA A 773
TRP A 806
MET A 807
SER A 810
LEU A 814
MET A 845
MET A 852
LEU A 938
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-3.4A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 0.42A 5mwyA-5mwpA:
43.2		 5mwyA-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
ALA A 773
TRP A 806
MET A 807
SER A 811
LEU A 814
MET A 845
MET A 852
LEU A 938
 ECV  A1101 ( 3.9A)
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.8A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-3.0A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 0.42A 5mwyA-5mwpA:
43.2		 5mwyA-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 6 GLN A 776
ARG A 817
PHE A 829
CYH A 942
THR A 945
PHE A 956
 ECV  A1101 (-2.9A)
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.27A 5mwyA-5mwpA:
43.2		 5mwyA-5mwpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 PHE A 835
CYH A 942
THR A 945
PHE A 956
 None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.14A 5mwyA-5mwpA:
43.2		 5mwyA-5mwpA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 0.59A 5nfpA-5mwpA:
35.2		 5nfpA-5mwpA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
 ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
 1.26A 5nfpA-5mwpA:
35.2		 5nfpA-5mwpA:
42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
ARG A 817
CYH A 849
MET A 852
 ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.7A)
 1.22A 5nfpA-5mwpA:
35.2		 5nfpA-5mwpA:
42.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
ALA A 773
MET A 807
LEU A 814
ARG A 817
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.32A 5toaA-5mwpA:
25.6		 5toaA-5mwpA:
15.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLY A 774
GLN A 776
LEU A 814
ARG A 817
CYH A 849
 ECV  A1101 (-4.7A)
ECV  A1101 ( 3.9A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
 0.81A 5uc1A-5mwpA:
22.9		 5uc1A-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLN A 776
LEU A 814
ARG A 817
CYH A 849
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.7A)
 1.00A 5uc1A-5mwpA:
22.9		 5uc1A-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLN A 776
TRP A 806
LEU A 814
ARG A 817
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
 1.22A 5uc1A-5mwpA:
22.9		 5uc1A-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLY A 774
GLN A 776
TRP A 806
LEU A 814
ARG A 817
 ECV  A1101 ( 3.9A)
None
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
 0.80A 5uc1A-5mwpA:
22.9		 5uc1A-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLY A 774
GLN A 776
LEU A 814
ARG A 817
CYH A 849
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
 0.84A 5uc1B-5mwpA:
23.0		 5uc1B-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLN A 776
LEU A 814
ARG A 817
CYH A 849
MET A 852
 ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.8A)
ECV  A1101 (-3.7A)
 0.98A 5uc1B-5mwpA:
23.0		 5uc1B-5mwpA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
TRP A 806
ARG A 817
PHE A 829
LEU A 938
CYH A 942
 ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.70A 5uc3A-5mwpA:
29.8		 5uc3A-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.27A 5uc3A-5mwpA:
29.8		 5uc3A-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
TRP A 806
ARG A 817
MET A 852
LEU A 938
 ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
 1.25A 5uc3B-5mwpA:
29.7		 5uc3B-5mwpA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
GLN A 776
TRP A 806
ARG A 817
PHE A 829
LEU A 938
CYH A 942
 ECV  A1101 (-4.7A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-4.0A)
ECV  A1101 ( 4.9A)
ECV  A1101 ( 4.3A)
ECV  A1101 (-4.0A)
 0.60A 5uc3B-5mwpA:
29.7		 5uc3B-5mwpA:
45.00