SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'EAH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3nhi D7 PROTEIN
(Anopheles
stephensi) 		4 / 6 LEU A 100
ALA A 116
LEU A 113
ALA A  53
 None
None
None
EAH  A   1 ( 4.3A)
 0.93A 2vcvK-3nhiA:
undetectable		 2vcvK-3nhiA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3dzt D7 PROTEIN
(Aedes
aegypti) 		4 / 4 PRO A  63
TYR A  61
GLY A  59
THR A  58
 None
None
None
EAH  A 305 ( 4.0A)
 1.42A 3ib0A-3dztA:
undetectable		 3ib0A-3dztA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3nhi D7 PROTEIN
(Anopheles
stephensi) 		5 / 12 ILE A  75
TYR A 117
VAL A 120
ALA A 116
GLY A 108
 None
EAH  A   1 (-4.6A)
None
None
None
 1.07A 5igiA-3nhiA:
1.7		 5igiA-3nhiA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3nhi D7 PROTEIN
(Anopheles
stephensi) 		5 / 12 ILE A  75
TYR A 117
VAL A 120
ALA A 116
GLY A 108
 None
EAH  A   1 (-4.6A)
None
None
None
 1.10A 5igjA-3nhiA:
undetectable		 5igjA-3nhiA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3nhi D7 PROTEIN
(Anopheles
stephensi) 		4 / 8 TYR A  82
ILE A  85
LEU A  13
ALA A  12
 None
None
EAH  A   1 (-4.8A)
None
 0.83A 5y7pC-3nhiA:
undetectable		 5y7pC-3nhiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 3nhi D7 PROTEIN
(Anopheles
stephensi) 		4 / 8 TYR A  82
ILE A  85
LEU A  13
ALA A  12
 None
None
EAH  A   1 (-4.8A)
None
 0.72A 5y7pE-3nhiA:
undetectable		 5y7pE-3nhiA:
21.02