SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'E9T'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_1 (RETINOIC ACID RECEPTOR, BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	9 / 12	PHE A 230 ALA A 234 CYH A 237 LEU A 268 LEU A 271 ILE A 275 ARG A 278 SER A 289 PHE A 304	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) E9T A 501 (-4.9A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A)	0.56A	1xdkB-6fx0A: 37.1	1xdkB-6fx0A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_1 (RETINOIC ACID RECEPTOR, BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	9 / 12	PHE A 230 ALA A 234 CYH A 237 LEU A 271 ILE A 275 ARG A 278 SER A 289 PHE A 304 LEU A 307	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) None	0.62A	1xdkB-6fx0A: 37.1	1xdkB-6fx0A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_2 (RETINOIC ACID RECEPTOR, BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	3 / 3	LEU A 233 PHE A 288 ARG A 396	E9T A 501 ( 4.3A) E9T A 501 (-4.7A) None	0.34A	1xdkF-6fx0A: 37.2	1xdkF-6fx0A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LBD_A_REAA500_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	11 / 12	PHE A 230 LYS A 236 CYH A 237 LEU A 271 ARG A 274 ILE A 275 ARG A 278 PHE A 288 SER A 289 GLY A 393 LEU A 400	E9T A 501 (-4.3A) None E9T A 501 (-3.6A) E9T A 501 (-3.6A) None E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-4.7A) E9T A 501 (-2.6A) E9T A 501 (-3.7A) None	0.45A	2lbdA-6fx0A: 39.9	2lbdA-6fx0A: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LBD_A_REAA500_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	10 / 12	PHE A 230 LYS A 236 CYH A 237 LEU A 271 MET A 272 ARG A 274 ILE A 275 ARG A 278 PHE A 288 SER A 289	E9T A 501 (-4.3A) None E9T A 501 (-3.6A) E9T A 501 (-3.6A) None None E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-4.7A) E9T A 501 (-2.6A)	0.73A	2lbdA-6fx0A: 39.9	2lbdA-6fx0A: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A9E_B_REAB1_1 (RETINOIC ACID RECEPTOR ALPHA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	9 / 11	PHE A 230 CYH A 237 LEU A 271 ILE A 275 ARG A 278 PHE A 288 SER A 289 PHE A 304 LEU A 400	E9T A 501 (-4.3A) E9T A 501 (-3.6A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-4.7A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) None	0.61A	3a9eB-6fx0A: 38.1	3a9eB-6fx0A: 16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	11 / 12	PHE A 230 ALA A 234 LEU A 268 LEU A 271 ILE A 275 ARG A 278 SER A 289 PHE A 304 GLY A 393 ALA A 397 ILE A 412	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-4.9A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) E9T A 501 (-3.7A) E9T A 501 ( 3.9A) E9T A 501 ( 4.8A)	0.49A	3lbdA-6fx0A: 39.9	3lbdA-6fx0A: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	8 / 12	PHE A 230 ALA A 234 LEU A 271 MET A 272 ILE A 275 ARG A 278 SER A 289 PHE A 304	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) None E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A)	0.73A	3lbdA-6fx0A: 39.9	3lbdA-6fx0A: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_A_REAA501_1 (RETINOIC ACID RECEPTOR BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	10 / 11	PHE A 230 CYH A 237 LEU A 268 LEU A 271 ARG A 278 PHE A 288 SER A 289 LEU A 307 LEU A 400 ILE A 412	E9T A 501 (-4.3A) E9T A 501 (-3.6A) E9T A 501 (-4.9A) E9T A 501 (-3.6A) E9T A 501 (-3.1A) E9T A 501 (-4.7A) E9T A 501 (-2.6A) None None E9T A 501 ( 4.8A)	0.55A	4dm8A-6fx0A: 38.4	4dm8A-6fx0A: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M24_A_9CRA501_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	11 / 12	TRP A 227 PHE A 230 ALA A 234 LEU A 271 ILE A 275 ARG A 278 SER A 289 PHE A 304 GLY A 393 LEU A 400 ILE A 412	None E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) E9T A 501 (-3.7A) None E9T A 501 ( 4.8A)	0.54A	5m24A-6fx0A: 40.5	5m24A-6fx0A: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M24_A_9CRA501_1 (RETINOIC ACID RECEPTOR GAMMA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	10 / 12	TRP A 227 PHE A 230 ALA A 234 LEU A 271 MET A 272 ILE A 275 ARG A 278 SER A 289 PHE A 304 ILE A 412	None E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) None E9T A 501 (-3.8A) E9T A 501 (-3.1A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) E9T A 501 ( 4.8A)	0.69A	5m24A-6fx0A: 40.5	5m24A-6fx0A: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_B_REAB503_1 (RETINOIC ACID RECEPTOR BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	9 / 12	PHE A 230 ALA A 234 CYH A 237 LEU A 268 LEU A 271 ILE A 275 PHE A 288 PHE A 304 LEU A 307	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) E9T A 501 (-4.9A) E9T A 501 (-3.6A) E9T A 501 (-3.8A) E9T A 501 (-4.7A) E9T A 501 (-4.2A) None	0.61A	5uanB-6fx0A: 37.8	5uanB-6fx0A: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_B_REAB503_1 (RETINOIC ACID RECEPTOR BETA)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	9 / 12	PHE A 230 ALA A 234 CYH A 237 LEU A 268 LEU A 271 PHE A 288 SER A 289 PHE A 304 LEU A 307	E9T A 501 (-4.3A) E9T A 501 (-3.7A) E9T A 501 (-3.6A) E9T A 501 (-4.9A) E9T A 501 (-3.6A) E9T A 501 (-4.7A) E9T A 501 (-2.6A) E9T A 501 (-4.2A) None	0.63A	5uanB-6fx0A: 37.8	5uanB-6fx0A: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_D_READ601_1 (RETINOIC ACID RECEPTOR)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	4 / 7	LEU A 268 LEU A 294 LEU A 307 GLY A 393	E9T A 501 (-4.9A) None None E9T A 501 (-3.7A)	0.46A	6eu9D-6fx0A: 28.6	6eu9D-6fx0A: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_D_READ601_1 (RETINOIC ACID RECEPTOR)	6fx0	RETINOIC ACID RECEPTOR GAMMA (Homo sapiens)	4 / 7	LEU A 268 PHE A 288 LEU A 294 LEU A 307	E9T A 501 (-4.9A) E9T A 501 (-4.7A) None None	0.63A	6eu9D-6fx0A: 28.6	6eu9D-6fx0A: 18.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XDK_B_9CRB600_1","RETINOIC ACID RECEPTOR, BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",9,"PHE A 230;ALA A 234;CYH A 237;LEU A 268;LEU A 271;ILE A 275;ARG A 278;SER A 289;PHE A 304","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);E9T A 501 (-4.9A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A)","0.56A","1xdkB-6fx0A:37.1",null],["1XDK_B_9CRB600_1","RETINOIC ACID RECEPTOR, BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",9,"PHE A 230;ALA A 234;CYH A 237;LEU A 271;ILE A 275;ARG A 278;SER A 289;PHE A 304;LEU A 307","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);None","0.62A","1xdkB-6fx0A:37.1","1xdkB-6fx0A:15.51"],["1XDK_F_9CRF1600_2","RETINOIC ACID RECEPTOR, BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",3,"LEU A 233;PHE A 288;ARG A 396","E9T A 501 ( 4.3A);E9T A 501 (-4.7A);None","0.34A","1xdkF-6fx0A:37.2","1xdkB-6fx0A:15.51"],["2LBD_A_REAA500_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",11,"PHE A 230;LYS A 236;CYH A 237;LEU A 271;ARG A 274;ILE A 275;ARG A 278;PHE A 288;SER A 289;GLY A 393;LEU A 400","E9T A 501 (-4.3A);None;E9T A 501 (-3.6A);E9T A 501 (-3.6A);None;E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-4.7A);E9T A 501 (-2.6A);E9T A 501 (-3.7A);None","0.45A","2lbdA-6fx0A:39.9","1xdkF-6fx0A:15.51"],["2LBD_A_REAA500_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",10,"PHE A 230;LYS A 236;CYH A 237;LEU A 271;MET A 272;ARG A 274;ILE A 275;ARG A 278;PHE A 288;SER A 289","E9T A 501 (-4.3A);None;E9T A 501 (-3.6A);E9T A 501 (-3.6A);None;None;E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-4.7A);E9T A 501 (-2.6A)","0.73A","2lbdA-6fx0A:39.9","2lbdA-6fx0A:16.80"],["3A9E_B_REAB1_1","RETINOIC ACID RECEPTOR ALPHA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",9,"PHE A 230;CYH A 237;LEU A 271;ILE A 275;ARG A 278;PHE A 288;SER A 289;PHE A 304;LEU A 400","E9T A 501 (-4.3A);E9T A 501 (-3.6A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-4.7A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);None","0.61A","3a9eB-6fx0A:38.1","2lbdA-6fx0A:16.80"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",11,"PHE A 230;ALA A 234;LEU A 268;LEU A 271;ILE A 275;ARG A 278;SER A 289;PHE A 304;GLY A 393;ALA A 397;ILE A 412","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-4.9A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);E9T A 501 (-3.7A);E9T A 501 ( 3.9A);E9T A 501 ( 4.8A)","0.49A","3lbdA-6fx0A:39.9","3a9eB-6fx0A:16.60"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",8,"PHE A 230;ALA A 234;LEU A 271;MET A 272;ILE A 275;ARG A 278;SER A 289;PHE A 304","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);None;E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A)","0.73A","3lbdA-6fx0A:39.9","3lbdA-6fx0A:16.80"],["4DM8_A_REAA501_1","RETINOIC ACID RECEPTOR BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",10,"PHE A 230;CYH A 237;LEU A 268;LEU A 271;ARG A 278;PHE A 288;SER A 289;LEU A 307;LEU A 400;ILE A 412","E9T A 501 (-4.3A);E9T A 501 (-3.6A);E9T A 501 (-4.9A);E9T A 501 (-3.6A);E9T A 501 (-3.1A);E9T A 501 (-4.7A);E9T A 501 (-2.6A);None;None;E9T A 501 ( 4.8A)","0.55A","4dm8A-6fx0A:38.4","3lbdA-6fx0A:16.80"],["5M24_A_9CRA501_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",11,"TRP A 227;PHE A 230;ALA A 234;LEU A 271;ILE A 275;ARG A 278;SER A 289;PHE A 304;GLY A 393;LEU A 400;ILE A 412","None;E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);E9T A 501 (-3.7A);None;E9T A 501 ( 4.8A)","0.54A","5m24A-6fx0A:40.5","4dm8A-6fx0A:15.93"],["5M24_A_9CRA501_1","RETINOIC ACID RECEPTOR GAMMA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",10,"TRP A 227;PHE A 230;ALA A 234;LEU A 271;MET A 272;ILE A 275;ARG A 278;SER A 289;PHE A 304;ILE A 412","None;E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);None;E9T A 501 (-3.8A);E9T A 501 (-3.1A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);E9T A 501 ( 4.8A)","0.69A","5m24A-6fx0A:40.5","5m24A-6fx0A:17.80"],["5UAN_B_REAB503_1","RETINOIC ACID RECEPTOR BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",9,"PHE A 230;ALA A 234;CYH A 237;LEU A 268;LEU A 271;ILE A 275;PHE A 288;PHE A 304;LEU A 307","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);E9T A 501 (-4.9A);E9T A 501 (-3.6A);E9T A 501 (-3.8A);E9T A 501 (-4.7A);E9T A 501 (-4.2A);None","0.61A","5uanB-6fx0A:37.8","5m24A-6fx0A:17.80"],["5UAN_B_REAB503_1","RETINOIC ACID RECEPTOR BETA","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",9,"PHE A 230;ALA A 234;CYH A 237;LEU A 268;LEU A 271;PHE A 288;SER A 289;PHE A 304;LEU A 307","E9T A 501 (-4.3A);E9T A 501 (-3.7A);E9T A 501 (-3.6A);E9T A 501 (-4.9A);E9T A 501 (-3.6A);E9T A 501 (-4.7A);E9T A 501 (-2.6A);E9T A 501 (-4.2A);None","0.63A","5uanB-6fx0A:37.8","5uanB-6fx0A:13.45"],["6EU9_D_READ601_1","RETINOIC ACID RECEPTOR","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",4,"LEU A 268;LEU A 294;LEU A 307;GLY A 393","E9T A 501 (-4.9A);None;None;E9T A 501 (-3.7A)","0.46A","6eu9D-6fx0A:28.6","5uanB-6fx0A:13.45"],["6EU9_D_READ601_1","RETINOIC ACID RECEPTOR","6fx0","RETINOIC ACID RECEPTOR GAMMA","Homo sapiens",4,"LEU A 268;PHE A 288;LEU A 294;LEU A 307","E9T A 501 (-4.9A);E9T A 501 (-4.7A);None;None","0.63A","6eu9D-6fx0A:28.6","6eu9D-6fx0A:18.28"]]