SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'E1Z'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5g0h HDAC6
(Danio
rerio) 		10 / 11 PRO A 464
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.49A 1c3sA-5g0hA:
41.0		 1c3sA-5g0hA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5g0h HDAC6
(Danio
rerio) 		6 / 11 PRO A 464
HIS A 574
HIS A 614
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.90A 1c3sA-5g0hA:
41.0		 1c3sA-5g0hA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 9 GLY A 582
PRO A 464
GLY A 743
GLY A 744
ASP A 705
 E1Z  A1801 (-3.6A)
None
ZN  A1804 ( 4.2A)
None
ZN  A1804 ( 2.5A)
 1.14A 1mxdA-5g0hA:
undetectable		 1mxdA-5g0hA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		9 / 12 HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 0.37A 1t69A-5g0hA:
41.4		 1t69A-5g0hA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 1v54A-5g0hA:
undetectable		 1v54A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 1v54N-5g0hA:
undetectable		 1v54N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 1v55A-5g0hA:
undetectable		 1v55A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 1v55N-5g0hA:
undetectable		 1v55N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 11 HIS A 573
HIS A 574
ASP A 612
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 ( 2.5A)
None
 1.16A 1zz1A-5g0hA:
50.2		 1zz1A-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		9 / 11 HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.42A 1zz1A-5g0hA:
50.2		 1zz1A-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 11 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.25A 1zz1A-5g0hA:
50.2		 1zz1A-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 11 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.07A 1zz1A-5g0hA:
50.2		 1zz1A-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		8 / 11 ILE A 532
HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.14A 1zz1A-5g0hA:
50.2		 1zz1A-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 574
ASP A 612
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 ( 2.5A)
None
 1.19A 1zz1B-5g0hA:
50.8
1zz1C-5g0hA:
50.6		 1zz1B-5g0hA:
20.11
1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		9 / 12 HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.33A 1zz1B-5g0hA:
50.8
1zz1C-5g0hA:
50.6		 1zz1B-5g0hA:
20.11
1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.07A 1zz1B-5g0hA:
50.8
1zz1C-5g0hA:
50.6		 1zz1B-5g0hA:
20.11
1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 ILE A 532
HIS A 573
HIS A 574
ASP A 612
GLY A 743
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 ( 4.2A)
 1.15A 1zz1B-5g0hA:
50.8
1zz1C-5g0hA:
50.6		 1zz1B-5g0hA:
20.11
1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.06A 1zz1C-5g0hA:
50.6		 1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		10 / 12 ILE A 532
HIS A 573
HIS A 574
GLY A 582
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.37A 1zz1C-5g0hA:
50.6		 1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 ILE A 532
HIS A 614
GLY A 582
ASP A 705
GLY A 743
 None
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
 1.09A 1zz1C-5g0hA:
50.6		 1zz1C-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		8 / 9 HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 0.39A 1zz1D-5g0hA:
50.4		 1zz1D-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g0h HDAC6
(Danio
rerio) 		6 / 9 ILE A 532
HIS A 573
HIS A 574
ASP A 612
ASP A 705
TYR A 745
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 1.05A 1zz1D-5g0hA:
50.4		 1zz1D-5g0hA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 2dyrA-5g0hA:
undetectable		 2dyrA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 2dyrN-5g0hA:
undetectable		 2dyrN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2dysN-5g0hA:
undetectable		 2dysN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2eijA-5g0hA:
undetectable		 2eijA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.71A 2eijN-5g0hA:
undetectable		 2eijN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2eikA-5g0hA:
undetectable		 2eikA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2eikN-5g0hA:
undetectable		 2eikN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2eilA-5g0hA:
undetectable		 2eilA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2eilN-5g0hA:
undetectable		 2eilN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.71A 2eimA-5g0hA:
undetectable		 2eimA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 2y69A-5g0hA:
undetectable		 2y69A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.68A 2y69N-5g0hA:
undetectable		 2y69N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 2zxwA-5g0hA:
undetectable		 2zxwA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.69A 2zxwN-5g0hA:
undetectable		 2zxwN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 3ablA-5g0hA:
undetectable		 3ablA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.75A 3ablN-5g0hA:
undetectable		 3ablN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.75A 3abmA-5g0hA:
undetectable		 3abmA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.67A 3abmN-5g0hA:
undetectable		 3abmN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.70A 3ag1N-5g0hA:
undetectable		 3ag1N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 3ag4N-5g0hA:
undetectable		 3ag4N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 3asnA-5g0hA:
undetectable		 3asnA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 3asnN-5g0hA:
undetectable		 3asnN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 3asoA-5g0hA:
undetectable		 3asoA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 3asoN-5g0hA:
undetectable		 3asoN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 5g0h HDAC6
(Danio
rerio) 		5 / 5 HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
 0.11A 3c0zA-5g0hA:
56.9		 3c0zA-5g0hA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g0h HDAC6
(Danio
rerio) 		5 / 8 HIS A 573
HIS A 574
ASP A 612
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 ( 2.5A)
None
 1.31A 3c0zB-5g0hA:
56.5		 3c0zB-5g0hA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g0h HDAC6
(Danio
rerio) 		8 / 8 HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
 0.23A 3c0zB-5g0hA:
56.5		 3c0zB-5g0hA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g0h HDAC6
(Danio
rerio) 		4 / 8 PHE A 643
ASP A 705
PHE A 583
ASP A 612
 E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
 0.80A 3c0zB-5g0hA:
56.5		 3c0zB-5g0hA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 5g0h HDAC6
(Danio
rerio) 		5 / 6 HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
 0.16A 3c0zC-5g0hA:
56.2		 3c0zC-5g0hA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 GLU A 576
HIS A 573
HIS A 615
 None
E1Z  A1801 (-3.9A)
None
 0.73A 3co4A-5g0hA:
undetectable		 3co4A-5g0hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 3dtuA-5g0hA:
undetectable		 3dtuA-5g0hA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 3dtuC-5g0hA:
undetectable		 3dtuC-5g0hA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.70A 3wg7A-5g0hA:
undetectable		 3wg7A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 3wg7N-5g0hA:
undetectable		 3wg7N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.68A 3x2qN-5g0hA:
undetectable		 3x2qN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		8 / 10 HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.58A 4bz6A-5g0hA:
40.8		 4bz6A-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 10 HIS A 573
HIS A 574
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.24A 4bz6A-5g0hA:
40.8		 4bz6A-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 10 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.23A 4bz6A-5g0hA:
40.8		 4bz6A-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 10 HIS A 574
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.44A 4bz6A-5g0hA:
40.8		 4bz6A-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		9 / 12 HIS A 573
HIS A 574
ASP A 612
HIS A 614
PHE A 643
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.59A 4bz6A-5g0hA:
40.8
4bz6B-5g0hA:
40.5		 4bz6A-5g0hA:
21.36
4bz6B-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 574
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.24A 4bz6A-5g0hA:
40.8
4bz6B-5g0hA:
40.5		 4bz6A-5g0hA:
21.36
4bz6B-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.21A 4bz6A-5g0hA:
40.8
4bz6B-5g0hA:
40.5		 4bz6A-5g0hA:
21.36
4bz6B-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 HIS A 574
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.41A 4bz6A-5g0hA:
40.8
4bz6B-5g0hA:
40.5		 4bz6A-5g0hA:
21.36
4bz6B-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.34A 4bz6A-5g0hA:
40.8
4bz6B-5g0hA:
40.5		 4bz6A-5g0hA:
21.36
4bz6B-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		10 / 12 HIS A 573
HIS A 574
GLY A 582
ASP A 612
HIS A 614
PHE A 643
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.59A 4bz6C-5g0hA:
40.5		 4bz6C-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 574
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.22A 4bz6C-5g0hA:
40.5		 4bz6C-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.21A 4bz6C-5g0hA:
40.5		 4bz6C-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 HIS A 574
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.43A 4bz6C-5g0hA:
40.5		 4bz6C-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		8 / 10 HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.58A 4bz6D-5g0hA:
40.9		 4bz6D-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 10 HIS A 573
HIS A 574
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.23A 4bz6D-5g0hA:
40.9		 4bz6D-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 10 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.22A 4bz6D-5g0hA:
40.9		 4bz6D-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 10 HIS A 574
HIS A 614
ASP A 705
PRO A 711
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.44A 4bz6D-5g0hA:
40.9		 4bz6D-5g0hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		11 / 12 HIS A 463
PRO A 464
HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.48A 4lxzA-5g0hA:
43.7		 4lxzA-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 HIS A 463
PRO A 464
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 None
None
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.19A 4lxzA-5g0hA:
43.7		 4lxzA-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.09A 4lxzA-5g0hA:
43.7		 4lxzA-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		10 / 11 HIS A 463
PRO A 464
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.45A 4lxzB-5g0hA:
43.7		 4lxzB-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		6 / 11 HIS A 463
PRO A 464
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 None
None
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.18A 4lxzB-5g0hA:
43.7		 4lxzB-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		6 / 11 PRO A 464
HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.08A 4lxzB-5g0hA:
43.7		 4lxzB-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		11 / 12 PRO A 464
HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.39A 4lxzC-5g0hA:
43.8		 4lxzC-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.09A 4lxzC-5g0hA:
43.8		 4lxzC-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 PRO A 464
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 None
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.18A 4lxzC-5g0hA:
43.8		 4lxzC-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 PRO A 570
HIS A 614
GLY A 582
ASP A 705
GLY A 743
 None
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
 1.23A 4lxzC-5g0hA:
43.8		 4lxzC-5g0hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		10 / 12 HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.41A 4qa0A-5g0hA:
41.7		 4qa0A-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.22A 4qa0A-5g0hA:
41.7		 4qa0A-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.00A 4qa0A-5g0hA:
41.7		 4qa0A-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.25A 4qa0A-5g0hA:
41.7		 4qa0A-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		9 / 11 HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.44A 4qa0B-5g0hA:
41.7		 4qa0B-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 11 HIS A 573
PHE A 583
HIS A 614
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
None
E1Z  A1801 (-4.4A)
 1.13A 4qa0B-5g0hA:
41.7		 4qa0B-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 11 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.01A 4qa0B-5g0hA:
41.7		 4qa0B-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 11 PHE A 583
HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.20A 4qa0B-5g0hA:
41.7		 4qa0B-5g0hA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		10 / 12 HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.38A 4qa2A-5g0hA:
41.4		 4qa2A-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.22A 4qa2A-5g0hA:
41.4		 4qa2A-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.01A 4qa2A-5g0hA:
41.4		 4qa2A-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PHE A 583
HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.17A 4qa2A-5g0hA:
41.4		 4qa2A-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		10 / 12 HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.36A 4qa2B-5g0hA:
41.8		 4qa2B-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 574
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.22A 4qa2B-5g0hA:
41.8		 4qa2B-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 573
HIS A 614
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.22A 4qa2B-5g0hA:
41.8		 4qa2B-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 HIS A 574
HIS A 614
ASP A 705
GLY A 743
TYR A 745
 E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 1.00A 4qa2B-5g0hA:
41.8		 4qa2B-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PHE A 583
HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 E1Z  A1801 (-3.9A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.16A 4qa2B-5g0hA:
41.8		 4qa2B-5g0hA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5b1aA-5g0hA:
undetectable		 5b1aA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.76A 5b1aN-5g0hA:
undetectable		 5b1aN-5g0hA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.97A 5eeiA-5g0hA:
68.2		 5eeiA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 PRO A 464
SER A 531
HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.19A 5eeiA-5g0hA:
68.2		 5eeiA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.98A 5eeiB-5g0hA:
67.5		 5eeiB-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 PRO A 464
SER A 531
HIS A 573
HIS A 574
GLY A 582
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.6A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.18A 5eeiB-5g0hA:
67.5		 5eeiB-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 HIS A 463
PRO A 464
SER A 531
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
GLY A 743
TYR A 745
 None
None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
ZN  A1804 ( 4.2A)
E1Z  A1801 (-4.4A)
 0.12A 5eenA-5g0hA:
67.6		 5eenA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		7 / 12 HIS A 463
SER A 531
HIS A 614
PHE A 643
ASP A 705
GLY A 744
TYR A 745
 None
E1Z  A1801 ( 3.3A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.15A 5eenA-5g0hA:
67.6		 5eenA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 HIS A 573
HIS A 574
ASP A 612
HIS A 614
ASP A 705
GLY A 703
 E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
 1.21A 5eenA-5g0hA:
67.6		 5eenA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 1.05A 5eenA-5g0hA:
67.6		 5eenA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 SER A 531
PHE A 643
ASP A 705
PHE A 583
ASP A 612
 E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
 1.22A 5eenA-5g0hA:
67.6		 5eenA-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 HIS A 463
PRO A 464
SER A 531
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
LEU A 712
TYR A 745
 None
None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.30A 5eenB-5g0hA:
67.3		 5eenB-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.09A 5eenB-5g0hA:
67.3		 5eenB-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 SER A 531
PHE A 643
ASP A 705
PHE A 583
ASP A 612
 E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
 1.21A 5eenB-5g0hA:
67.3		 5eenB-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 ASP A 460
HIS A 463
PRO A 464
SER A 531
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
TYR A 745
 EDO  A1811 (-4.2A)
None
None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 0.24A 5ef8A-5g0hA:
67.6		 5ef8A-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-4.4A)
 0.98A 5ef8A-5g0hA:
67.6		 5ef8A-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 SER A 531
PHE A 643
ASP A 705
PHE A 583
ASP A 612
 E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
 1.22A 5ef8A-5g0hA:
67.6		 5ef8A-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		12 / 12 ASP A 460
PRO A 464
SER A 531
HIS A 573
HIS A 574
PHE A 583
ASP A 612
HIS A 614
PHE A 643
ASP A 705
LEU A 712
TYR A 745
 EDO  A1811 (-4.2A)
None
E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.9A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
ZN  A1804 (-3.2A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 0.26A 5ef8B-5g0hA:
67.2		 5ef8B-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		6 / 12 PRO A 464
HIS A 574
HIS A 614
ASP A 705
LEU A 712
TYR A 745
 None
E1Z  A1801 (-3.8A)
ZN  A1804 (-3.2A)
ZN  A1804 ( 2.5A)
None
E1Z  A1801 (-4.4A)
 1.06A 5ef8B-5g0hA:
67.2		 5ef8B-5g0hA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5g0h HDAC6
(Danio
rerio) 		5 / 12 SER A 531
PHE A 643
ASP A 705
PHE A 583
ASP A 612
 E1Z  A1801 ( 3.3A)
E1Z  A1801 (-3.6A)
ZN  A1804 ( 2.5A)
E1Z  A1801 (-3.9A)
ZN  A1804 (-2.1A)
 1.20A 5ef8B-5g0hA:
67.2		 5ef8B-5g0hA:
48.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 5iy5A-5g0hA:
undetectable		 5iy5A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 5iy5N-5g0hA:
undetectable		 5iy5N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 5xdqA-5g0hA:
undetectable		 5xdqA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5xdqN-5g0hA:
undetectable		 5xdqN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5xdxA-5g0hA:
undetectable		 5xdxA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 5xdxN-5g0hA:
undetectable		 5xdxN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 5z84A-5g0hA:
undetectable		 5z84A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 5z84N-5g0hA:
undetectable		 5z84N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.74A 5z85A-5g0hA:
undetectable		 5z85A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5z85N-5g0hA:
undetectable		 5z85N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.68A 5z86A-5g0hA:
undetectable		 5z86A-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.70A 5z86N-5g0hA:
undetectable		 5z86N-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5zcoA-5g0hA:
undetectable		 5zcoA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.71A 5zcoN-5g0hA:
undetectable		 5zcoN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5zcpA-5g0hA:
undetectable		 5zcpA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5zcpN-5g0hA:
undetectable		 5zcpN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.73A 5zcqA-5g0hA:
undetectable		 5zcqA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.72A 5zcqN-5g0hA:
undetectable		 5zcqN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.71A 6hu9a-5g0hA:
undetectable		 6hu9a-5g0hA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.77A 6hu9m-5g0hA:
undetectable		 6hu9m-5g0hA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.75A 6nknA-5g0hA:
undetectable		 6nknA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.75A 6nknN-5g0hA:
undetectable		 6nknN-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.75A 6nmpA-5g0hA:
undetectable		 6nmpA-5g0hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5g0h HDAC6
(Danio
rerio) 		3 / 3 HIS A 614
HIS A 574
HIS A 573
 ZN  A1804 (-3.2A)
E1Z  A1801 (-3.8A)
E1Z  A1801 (-3.9A)
 0.76A 6nmpN-5g0hA:
undetectable		 6nmpN-5g0hA:
20.95