SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'E0V'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1F9G_A_ASCA950_0 (HYALURONATE LYASE)	6bo6	- (-)	4 / 7	ARG A 340 TYR A 485 ARG A 574 ASN A 578	None E0V A 701 (-4.4A) E0V A 701 (-3.8A) E0V A 701 (-3.0A)	1.24A	1f9gA-6bo6A: undetectable	1f9gA-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TMX_B_BEZB882_0 (HYDROXYQUINOL 1,2-DIOXYGENASE)	6bo6	- (-)	5 / 12	GLY A 307 TYR A 346 ILE A 362 ARG A 340 HIS A 343	None None None None E0V A 701 (-3.9A)	1.32A	1tmxB-6bo6A: undetectable	1tmxB-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X70_A_715A801_1 (DIPEPTIDYL PEPTIDASE IV)	6bo6	- (-)	5 / 12	ARG A 340 GLU A 516 PHE A 173 ASN A 479 VAL A 459	None E0V A 701 (-2.6A) None E0V A 701 ( 4.7A) None	1.40A	1x70A-6bo6A: undetectable	1x70A-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZWP_A_NIMA401_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	6bo6	- (-)	4 / 5	LEU A 582 GLY A 518 TRP A 561 ASP A 520	None None E0V A 701 (-3.9A) None	1.39A	1zwpA-6bo6A: undetectable	1zwpA-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_B_NBVB1504_1 (GLUCOSYLCERAMIDASE)	6bo6	- (-)	5 / 11	ASN A 424 GLU A 425 TYR A 481 GLU A 516 TRP A 561	E0V A 701 (-3.3A) E0V A 701 (-2.6A) E0V A 701 (-4.4A) E0V A 701 (-2.6A) E0V A 701 (-3.9A)	0.72A	2v3dB-6bo6A: 15.1	2v3dB-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K13_B_THHB643_0 (5-METHYLTETRAHYDROFO LATE-HOMOCYSTEINE METHYLTRANSFERASE)	6bo6	- (-)	5 / 12	ASN A 424 VAL A 457 GLY A 307 ASN A 562 ARG A 587	E0V A 701 (-3.3A) None None None None	0.88A	3k13B-6bo6A: 6.9	3k13B-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WBV_A_SAMA402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	6bo6	- (-)	3 / 3	HIS A 309 GLU A 516 ASN A 424	None E0V A 701 (-2.6A) E0V A 701 (-3.3A)	1.01A	5wbvA-6bo6A: undetectable	5wbvA-6bo6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WBV_B_SAMB402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	6bo6	- (-)	3 / 3	HIS A 309 GLU A 516 ASN A 424	None E0V A 701 (-2.6A) E0V A 701 (-3.3A)	1.02A	5wbvB-6bo6A: undetectable	5wbvB-6bo6A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1F9G_A_ASCA950_0","HYALURONATE LYASE","6bo6","-","-",4,"ARG A 340;TYR A 485;ARG A 574;ASN A 578","None;E0V A 701 (-4.4A);E0V A 701 (-3.8A);E0V A 701 (-3.0A)","1.24A","1f9gA-6bo6A:undetectable",null],["1TMX_B_BEZB882_0","HYDROXYQUINOL 1,2-DIOXYGENASE","6bo6","-","-",5,"GLY A 307;TYR A 346;ILE A 362;ARG A 340;HIS A 343","None;None;None;None;E0V A 701 (-3.9A)","1.32A","1tmxB-6bo6A:undetectable","1f9gA-6bo6A:undetectable"],["1X70_A_715A801_1","DIPEPTIDYL PEPTIDASE IV","6bo6","-","-",5,"ARG A 340;GLU A 516;PHE A 173;ASN A 479;VAL A 459","None;E0V A 701 (-2.6A);None;E0V A 701 ( 4.7A);None","1.40A","1x70A-6bo6A:undetectable","1tmxB-6bo6A:undetectable"],["1ZWP_A_NIMA401_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","6bo6","-","-",4,"LEU A 582;GLY A 518;TRP A 561;ASP A 520","None;None;E0V A 701 (-3.9A);None","1.39A","1zwpA-6bo6A:undetectable","1x70A-6bo6A:undetectable"],["2V3D_B_NBVB1504_1","GLUCOSYLCERAMIDASE","6bo6","-","-",5,"ASN A 424;GLU A 425;TYR A 481;GLU A 516;TRP A 561","E0V A 701 (-3.3A);E0V A 701 (-2.6A);E0V A 701 (-4.4A);E0V A 701 (-2.6A);E0V A 701 (-3.9A)","0.72A","2v3dB-6bo6A:15.1","1zwpA-6bo6A:undetectable"],["3K13_B_THHB643_0","5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE","6bo6","-","-",5,"ASN A 424;VAL A 457;GLY A 307;ASN A 562;ARG A 587","E0V A 701 (-3.3A);None;None;None;None","0.88A","3k13B-6bo6A:6.9","2v3dB-6bo6A:undetectable"],["5WBV_A_SAMA402_1","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","6bo6","-","-",3,"HIS A 309;GLU A 516;ASN A 424","None;E0V A 701 (-2.6A);E0V A 701 (-3.3A)","1.01A","5wbvA-6bo6A:undetectable","3k13B-6bo6A:undetectable"],["5WBV_B_SAMB402_1","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","6bo6","-","-",3,"HIS A 309;GLU A 516;ASN A 424","None;E0V A 701 (-2.6A);E0V A 701 (-3.3A)","1.02A","5wbvB-6bo6A:undetectable","5wbvA-6bo6A:undetectable"]]