SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DZW'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
SER A 265
SER A 306
CYH A 316
LEU A 419
 DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
None
 1.31A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		9 / 12 TYR A 175
LEU A 258
LEU A 261
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
LEU A 337
 None
DZW  A 501 (-3.8A)
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
None
 0.70A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
None
 1.24A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		11 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.31A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.47A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		8 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 303
SER A 306
CYH A 316
LEU A 337
HIS A 333
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
None
DZW  A 501 (-3.9A)
 1.49A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 6 LEU A 255
ILE A 299
ARG A 302
TRP A 314
TYR A 323
VAL A 444
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.6A)
None
 0.28A 1db1A-6fobA:
37.2		 1db1A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		9 / 12 TYR A 175
LEU A 258
LEU A 261
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
LEU A 341
 None
DZW  A 501 (-3.8A)
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
None
 0.81A 1ie9A-6fobA:
37.3		 1ie9A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		11 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
HIS A 333
LEU A 341
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.36A 1ie9A-6fobA:
37.3		 1ie9A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		4 / 4 LEU A 255
ILE A 299
ARG A 302
TRP A 314
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
 0.32A 1ie9A-6fobA:
37.3		 1ie9A-6fobA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 LEU A 261
SER A 265
SER A 306
TRP A 314
CYH A 316
LEU A 419
 DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
None
 1.43A 1rk3A-6fobA:
38.9		 1rk3A-6fobA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.35A 1rk3A-6fobA:
38.9		 1rk3A-6fobA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
None
 1.30A 1rk3A-6fobA:
38.9		 1rk3A-6fobA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
SER A 306
TRP A 314
CYH A 316
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.27A 1rk3A-6fobA:
38.9		 1rk3A-6fobA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		4 / 4 LEU A 255
ILE A 299
ARG A 302
TYR A 427
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-4.9A)
 0.12A 1rk3A-6fobA:
38.9		 1rk3A-6fobA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 LEU A 255
LEU A 261
VAL A 262
ILE A 299
SER A 303
SER A 306
TRP A 314
CYH A 316
TYR A 323
VAL A 328
LEU A 337
LEU A 341
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
DZW  A 501 (-3.6A)
DZW  A 501 ( 4.3A)
None
None
 0.30A 1s19A-6fobA:
37.4		 1s19A-6fobA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 5 TYR A 175
SER A 265
ARG A 302
HIS A 333
HIS A 423
 None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.9A)
DZW  A 501 (-4.0A)
 0.17A 1s19A-6fobA:
37.4		 1s19A-6fobA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 PHE A 182
LEU A 261
SER A 265
SER A 306
CYH A 316
LEU A 419
 None
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
None
 1.33A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		8 / 12 PHE A 185
LEU A 261
VAL A 262
SER A 265
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 1.32A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
PHE A 182
LEU A 261
VAL A 262
LEU A 338
HIS A 333
 None
None
DZW  A 501 ( 4.5A)
None
None
DZW  A 501 (-3.9A)
 1.43A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
PHE A 182
LEU A 261
VAL A 262
SER A 265
LEU A 338
 None
None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
None
 1.12A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
PHE A 182
LEU A 261
VAL A 262
SER A 265
SER A 306
CYH A 316
VAL A 328
HIS A 333
LEU A 337
HIS A 423
LEU A 430
 None
None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
None
 0.20A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 7 LEU A 255
ILE A 299
ARG A 302
SER A 303
TRP A 314
TYR A 427
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
DZW  A 501 (-4.9A)
 0.20A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 7 LEU A 255
LEU A 258
ARG A 302
SER A 303
TRP A 314
 None
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
 0.89A 2hc4A-6fobA:
41.3		 2hc4A-6fobA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
SER A 265
SER A 306
CYH A 316
LEU A 419
 DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
None
 1.31A 2zlcA-6fobA:
38.9		 2zlcA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.33A 2zlcA-6fobA:
38.9		 2zlcA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
None
 1.26A 2zlcA-6fobA:
38.9		 2zlcA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
HIS A 333
LEU A 337
HIS A 423
LEU A 430
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
None
 0.34A 2zlcA-6fobA:
38.9		 2zlcA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 5 LEU A 255
ILE A 299
ARG A 302
TRP A 314
TYR A 427
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
DZW  A 501 (-4.9A)
 0.19A 2zlcA-6fobA:
38.9		 2zlcA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		7 / 12 TYR A 175
LEU A 258
LEU A 261
SER A 303
SER A 306
CYH A 316
VAL A 328
 None
DZW  A 501 (-3.8A)
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
 0.84A 3m7rA-6fobA:
37.4		 3m7rA-6fobA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		9 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 303
SER A 306
CYH A 316
VAL A 328
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
None
DZW  A 501 (-4.0A)
 0.24A 3m7rA-6fobA:
37.4		 3m7rA-6fobA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		9 / 12 TYR A 175
VAL A 262
SER A 265
SER A 303
SER A 306
CYH A 316
VAL A 328
LEU A 337
HIS A 423
 None
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
None
DZW  A 501 (-4.0A)
 0.60A 3m7rA-6fobA:
37.4		 3m7rA-6fobA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		9 / 9 PHE A 182
LEU A 255
ILE A 299
ARG A 302
TRP A 314
TYR A 323
LEU A 341
TYR A 427
VAL A 444
 None
None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.6A)
None
DZW  A 501 (-4.9A)
None
 0.36A 3m7rA-6fobA:
37.4		 3m7rA-6fobA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 9 PHE A 182
TYR A 323
LEU A 338
TYR A 427
VAL A 444
 None
DZW  A 501 (-3.6A)
None
DZW  A 501 (-4.9A)
None
 1.48A 3m7rA-6fobA:
37.4		 3m7rA-6fobA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 LEU A 261
SER A 265
SER A 306
TRP A 314
CYH A 316
LEU A 419
 DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
None
 1.44A 3vt3A-6fobA:
38.3		 3vt3A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.33A 3vt3A-6fobA:
38.3		 3vt3A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		6 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
None
 1.30A 3vt3A-6fobA:
38.3		 3vt3A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
SER A 303
SER A 306
TRP A 314
CYH A 316
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.30A 3vt3A-6fobA:
38.3		 3vt3A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		5 / 12 LEU A 261
VAL A 262
SER A 303
LEU A 338
HIS A 333
 DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.8A)
None
DZW  A 501 (-3.9A)
 1.31A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		7 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
ARG A 302
SER A 303
LEU A 338
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
None
 1.18A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		11 / 12 TYR A 175
LEU A 261
VAL A 262
SER A 265
ARG A 302
SER A 303
SER A 306
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.5A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.26A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		11 / 12 TYR A 175
TYR A 179
VAL A 262
SER A 265
ARG A 302
SER A 303
SER A 306
VAL A 328
HIS A 333
LEU A 337
HIS A 423
 None
DZW  A 501 ( 4.8A)
None
DZW  A 501 (-3.0A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
None
DZW  A 501 (-4.0A)
 0.62A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		4 / 4 LEU A 255
ILE A 299
TYR A 323
TYR A 427
 None
DZW  A 501 (-4.7A)
DZW  A 501 (-3.6A)
DZW  A 501 (-4.9A)
 0.42A 3vt7A-6fobA:
36.5		 3vt7A-6fobA:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
VAL A 262
SER A 265
ILE A 299
ARG A 302
SER A 303
SER A 306
TRP A 314
CYH A 316
VAL A 328
HIS A 333
HIS A 423
 None
None
DZW  A 501 (-3.0A)
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
DZW  A 501 (-4.0A)
 0.23A 4rujA-6fobA:
41.0		 4rujA-6fobA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		7 / 12 TYR A 175
VAL A 262
SER A 303
SER A 306
TRP A 314
CYH A 316
HIS A 333
 None
None
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.4A)
DZW  A 501 (-3.9A)
 1.32A 4rujA-6fobA:
41.0		 4rujA-6fobA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		8 / 12 PHE A 185
LEU A 261
SER A 265
ILE A 299
ARG A 302
VAL A 328
HIS A 333
HIS A 423
 None
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
DZW  A 501 (-4.0A)
 1.29A 5h1eA-6fobA:
38.0		 5h1eA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		12 / 12 TYR A 175
PHE A 182
LEU A 261
SER A 265
ILE A 299
ARG A 302
SER A 303
SER A 306
TRP A 314
VAL A 328
HIS A 333
HIS A 423
 None
None
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.0A)
DZW  A 501 (-4.7A)
DZW  A 501 (-3.8A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 ( 4.3A)
DZW  A 501 (-3.9A)
DZW  A 501 (-4.0A)
 0.34A 5h1eA-6fobA:
38.0		 5h1eA-6fobA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 6fob VITAMIN D3 RECEPTOR
A
(Danio
rerio) 		7 / 12 TYR A 175
PHE A 182
LEU A 261
SER A 303
SER A 306
TRP A 314
HIS A 333
 None
None
DZW  A 501 ( 4.5A)
DZW  A 501 (-3.8A)
DZW  A 501 (-2.7A)
DZW  A 501 (-3.5A)
DZW  A 501 (-3.9A)
 1.15A 5h1eA-6fobA:
38.0		 5h1eA-6fobA:
21.78