SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DUV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5ydl PKS
(Streptomyces
sp.
CNQ431) 		5 / 9 ALA A 230
THR A 325
ALA A 231
VAL A 274
ALA A 270
 None
None
None
None
DUV  A 501 ( 4.1A)
 1.01A 4qvnK-5ydlA:
undetectable
4qvnL-5ydlA:
undetectable		 4qvnK-5ydlA:
18.89
4qvnL-5ydlA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5ydl PKS
(Streptomyces
sp.
CNQ431) 		5 / 9 ALA A 230
THR A 325
ALA A 231
VAL A 274
ALA A 270
 None
None
None
None
DUV  A 501 ( 4.1A)
 1.01A 4qvnY-5ydlA:
undetectable
4qvnZ-5ydlA:
undetectable		 4qvnY-5ydlA:
18.89
4qvnZ-5ydlA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 5ydl PKS
(Streptomyces
sp.
CNQ431) 		5 / 9 THR A  94
GLY A  93
GLY A  92
HIS A 172
VAL A 326
 None
None
DUV  A 501 (-4.2A)
None
None
 1.43A 6gnfA-5ydlA:
undetectable		 6gnfA-5ydlA:
9.78