SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DTT'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AXW_A_MTXA732_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.00A	1axwA-5by6A: 36.3	1axwA-5by6A: 47.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AXW_A_MTXA732_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	LYS A  71 ILE A 102 ASP A 212 LEU A 215 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.00A	1axwA-5by6A: 36.3	1axwA-5by6A: 47.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AXW_B_MTXB733_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.95A	1axwB-5by6A: 36.6	1axwB-5by6A: 47.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AXW_B_MTXB733_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 11	LYS A  71 ILE A 102 ASP A 212 LEU A 215 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.94A	1axwB-5by6A: 36.6	1axwB-5by6A: 47.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_B_CHDB1250_1 (ALCOHOL DEHYDROGENASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 11	CYH A  50 SER A  52 HIS A  72 LEU A 122 CYH A 166	ZN  A1000 (-2.3A) DTT  A 700 (-2.4A) ZN  A1000 ( 3.3A) None ZN  A1000 ( 2.3A)	0.78A	1ee2B-1yqdA: 34.9	1ee2B-1yqdA: 25.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_A_D16A414_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	8 / 12	PHE A  74 GLU A  81 ILE A 102 ASN A 106 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.76A	1hvyA-5by6A: 13.0	1hvyA-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_A_D16A414_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	PHE A  74 GLU A  81 ILE A 102 TRP A 103 ASN A 106 PHE A 219	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A)	0.56A	1hvyA-5by6A: 13.0	1hvyA-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_B_D16B415_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 12	GLU A  81 ILE A 102 ASN A 106 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.83A	1hvyB-5by6A: 42.6	1hvyB-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_B_D16B415_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 TRP A 103 ASN A 106 PHE A 219	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A)	0.60A	1hvyB-5by6A: 42.6	1hvyB-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_C_D16C416_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	8 / 11	PHE A  74 GLU A  81 ILE A 102 ASN A 106 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.64A	1hvyC-5by6A: 13.1	1hvyC-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_C_D16C416_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 11	PHE A  74 GLU A  81 ILE A 102 TRP A 103 ASN A 106 PHE A 219	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A)	0.57A	1hvyC-5by6A: 13.1	1hvyC-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	GLU A  81 ASP A 212 LEU A 215 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 (-3.0A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.70A	1hvyD-5by6A: 42.3	1hvyD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	GLU A  81 ILE A 102 ASN A 106 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.76A	1hvyD-5by6A: 42.3	1hvyD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.75A	1hvyD-5by6A: 42.3	1hvyD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	GLU A  81 ILE A 102 TRP A 103 ASN A 106 LEU A 186 PHE A 219	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None DTT  A 402 ( 4.1A)	0.87A	1hvyD-5by6A: 42.3	1hvyD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I00_A_D16A315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	8 / 9	PHE A  74 GLU A  81 ILE A 102 TRP A 103 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.57A	1i00A-5by6A: 41.9	1i00A-5by6A: 64.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I00_B_D16B409_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 9	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.37A	1i00B-5by6A: 12.7	1i00B-5by6A: 64.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHO_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.25A	1jhoA-1yqdA: 2.4	1jhoA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHQ_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 8	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.25A	1jhqA-1yqdA: 2.4	1jhqA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHR_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.24A	1jhrA-1yqdA: 2.5	1jhrA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHY_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.25A	1jhyA-1yqdA: 2.4	1jhyA-1yqdA: 22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_A_LYAA317_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.85A	1ju6A-5by6A: 41.8	1ju6A-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_A_LYAA317_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 ASN A 106 GLY A 216 PHE A 219	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A)	1.12A	1ju6A-5by6A: 41.8	1ju6A-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_A_LYAA317_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.05A	1ju6A-5by6A: 41.8	1ju6A-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_A_LYAA317_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 TRP A 103 ASN A 106 PHE A 219	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A)	0.74A	1ju6A-5by6A: 41.8	1ju6A-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_D_LYAD315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	LYS A  71 PHE A  74 ILE A 102 ASN A 106 GLY A 216	None None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A)	1.15A	1ju6D-5by6A: 41.9	1ju6D-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JU6_D_LYAD315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	LYS A  71 PHE A  74 ILE A 102 GLY A 216 TYR A 252	None None DTT  A 402 ( 4.3A) UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.17A	1ju6D-5by6A: 41.9	1ju6D-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_A_LYAA315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.14A	1jujA-5by6A: 41.3	1jujA-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_A_LYAA315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	LYS A  71 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.07A	1jujA-5by6A: 41.3	1jujA-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_B_LYAB315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.14A	1jujB-5by6A: 41.3	1jujB-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_B_LYAB315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	LYS A  71 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.07A	1jujB-5by6A: 41.3	1jujB-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_C_LYAC315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.14A	1jujC-5by6A: 41.3	1jujC-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_C_LYAC315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	LYS A  71 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.07A	1jujC-5by6A: 41.3	1jujC-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_D_LYAD315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.14A	1jujD-5by6A: 41.3	1jujD-5by6A: 62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1JUJ_D_LYAD315_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	LYS A  71 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.07A	1jujD-5by6A: 41.3	1jujD-5by6A: 62.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L4N_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.23A	1l4nA-1yqdA: 2.5	1l4nA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5K_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.26A	1l5kA-1yqdA: 2.5	1l5kA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5L_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.24A	1l5lA-1yqdA: 2.2	1l5lA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5M_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	1yqd	SINAPYL ALCOHOL DEHYDROGENASE (Populus tremuloides)	5 / 9	THR A 170 GLY A 302 LEU A 195 SER A  52 GLY A 278	NAP  A 500 (-3.1A) NAP  A 500 (-3.2A) NAP  A 500 (-3.4A) DTT  A 700 (-2.4A) NAP  A 500 (-3.4A)	1.25A	1l5mA-1yqdA: 2.7	1l5mA-1yqdA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIN_A_TFPA155_1 (CALMODULIN)	2pan	GLYOXYLATE CARBOLIGASE (Escherichia coli)	4 / 7	GLN A 258 PHE A 365 MET A 403 ALA A 401	DTT  A 901 ( 3.8A) None None None	1.28A	1linA-2panA: undetectable	1linA-2panA: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC2199_0 (PROTEIN (METHIONINE REPRESSOR))	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	5 / 12	GLY A 346 GLU A 368 ARG A 371 ARG A 372 LEU A 316	None None DTT  A1400 (-3.1A) DTT  A1400 (-3.6A) None	1.06A	1mj2C-4c2kA: undetectable 1mj2D-4c2kA: undetectable	1mj2C-4c2kA: 13.79 1mj2D-4c2kA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJL_A_SAMA200_0 (METHIONINE REPRESSOR PROTEIN METJ)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	5 / 11	ALA A 192 GLU A 368 ARG A 371 ARG A 372 LEU A 316	None None DTT  A1400 (-3.1A) DTT  A1400 (-3.6A) None	1.29A	1mjlA-4c2kA: undetectable 1mjlB-4c2kA: undetectable	1mjlA-4c2kA: 13.79 1mjlB-4c2kA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_C_SAMC200_0 (METHIONINE REPRESSOR)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	5 / 12	GLY A 346 GLU A 368 ARG A 371 ARG A 372 LEU A 316	None None DTT  A1400 (-3.1A) DTT  A1400 (-3.6A) None	1.10A	1mjoC-4c2kA: undetectable 1mjoD-4c2kA: undetectable	1mjoC-4c2kA: 13.79 1mjoD-4c2kA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_B_FUAB703_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3rty	PERIOD CIRCADIAN PROTEIN (Drosophila melanogaster)	3 / 3	VAL A 409 ALA A 408 HIS A 493	DTT  A 900 (-4.9A) None None	0.52A	1q23C-3rtyA: undetectable	1q23C-3rtyA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3rty	PERIOD CIRCADIAN PROTEIN (Drosophila melanogaster)	3 / 3	VAL A 409 ALA A 408 HIS A 493	DTT  A 900 (-4.9A) None None	0.59A	1q23H-3rtyA: undetectable	1q23H-3rtyA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_I_FUAI707_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3rty	PERIOD CIRCADIAN PROTEIN (Drosophila melanogaster)	3 / 3	VAL A 409 ALA A 408 HIS A 493	DTT  A 900 (-4.9A) None None	0.51A	1q23G-3rtyA: undetectable	1q23G-3rtyA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_K_FUAK712_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3rty	PERIOD CIRCADIAN PROTEIN (Drosophila melanogaster)	3 / 3	VAL A 409 ALA A 408 HIS A 493	DTT  A 900 (-4.9A) None None	0.59A	1q23L-3rtyA: undetectable	1q23L-3rtyA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_L_FUAL710_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3rty	PERIOD CIRCADIAN PROTEIN (Drosophila melanogaster)	3 / 3	VAL A 409 ALA A 408 HIS A 493	DTT  A 900 (-4.9A) None None	0.54A	1q23J-3rtyA: undetectable	1q23J-3rtyA: 20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_A_D16A309_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 8	PHE A  74 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.41A	1rtsA-5by6A: 43.1	1rtsA-5by6A: 62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_A_D16A309_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 8	PHE A  74 ILE A 102 ASP A 212 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.36A	1rtsA-5by6A: 43.1	1rtsA-5by6A: 62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_B_D16B409_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.41A	1rtsB-5by6A: 43.0	1rtsB-5by6A: 62.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AZY_A_CHDA237_0 (PHOSPHOLIPASE A2, MAJOR ISOENZYME)	1hkx	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN (Mus musculus)	5 / 11	ARG A 346 ILE A 350 ILE A 429 HIS A 420 MET A 422	DTT  A1475 ( 3.7A) None None None None	1.20A	2azyA-1hkxA: undetectable	2azyA-1hkxA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_B_SAMB1217_1 (CATECHOL O-METHYLTRANSFERASE)	3r6n	DESMOPLAKIN (Homo sapiens)	4 / 6	GLU A 293 TYR A 296 GLN A 318 ASP A 369	None None DTT  A   3 (-3.6A) None	1.34A	2cl5B-3r6nA: undetectable	2cl5B-3r6nA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HS1_B_017B203_1 (HIV-1 PROTEASE)	1tiq	PROTEASE SYNTHASE AND SPORULATION NEGATIVE REGULATORY PROTEIN PAI 1 (Bacillus subtilis)	4 / 7	GLU A 160 PRO A  34 MET A  37 GLY A 158	None None DTT  A1201 (-4.3A) DTT  A1201 (-3.7A)	1.16A	2hs1B-1tiqA: undetectable	2hs1B-1tiqA: 19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6K_A_ADNA699_1 (CHLORINASE)	3r0h	INACTIVATION-NO-AFTE R-POTENTIAL D PROTEIN (Drosophila melanogaster)	4 / 7	PHE A 642 TYR A 521 PRO A 601 THR A 607	DTT  A   5 ( 3.3A) None None None	1.20A	2q6kA-3r0hA: undetectable	2q6kA-3r0hA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA507_0 (CHORISMATE SYNTHASE)	4c2k	3-KETOACYL-COA THIOLASE, MITOCHONDRIAL (Homo sapiens)	3 / 3	LEU A 316 ASN A 344 ARG A 372	None None DTT  A1400 (-3.6A)	0.83A	2qhfA-4c2kA: undetectable	2qhfA-4c2kA: 23.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_A_D16A309_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.41A	2tsrA-5by6A: 43.0	2tsrA-5by6A: 62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_C_D16C509_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 10	PHE A  74 GLU A  81 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.46A	2tsrC-5by6A: 42.8	2tsrC-5by6A: 62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_C_D16C509_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	PHE A  74 GLU A  81 ILE A 102 TRP A 103 PHE A 219	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) DTT  A 402 ( 4.1A)	0.70A	2tsrC-5by6A: 42.8	2tsrC-5by6A: 62.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_D_D16D609_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 9	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.41A	2tsrD-5by6A: 12.9	2tsrD-5by6A: 62.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDB_A_NPSA1591_1 (SERUM ALBUMIN)	5tqm	CINNAMOYL-COA REDUCTASE (Sorghum bicolor)	4 / 8	ILE A 150 LEU A 271 PHE A 312 TYR A 310	DTT  A 403 (-4.5A) None None None	0.83A	2vdbA-5tqmA: undetectable	2vdbA-5tqmA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQ5_B_LDPB1197_1 (S-NORCOCLAURINE SYNTHASE)	1w27	PHENYLALANINE AMMONIA-LYASE 1 (Petroselinum crispum)	4 / 7	LEU A 138 LEU A 134 PHE A 137 GLU A 484	None None DTT  A1717 (-4.9A) DTT  A1717 ( 3.9A)	0.66A	2vq5B-1w27A: undetectable	2vq5B-1w27A: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1358_1 (PROSTAGLANDIN REDUCTASE 2)	5n2g	DNA POLYMERASE (Vaccinia virus)	4 / 6	ASP A 330 TYR A 332 TYR A 473 PHE A 164	None None DTT  A1110 (-4.7A) None	1.19A	2w98A-5n2gA: undetectable 2w98B-5n2gA: undetectable	2w98A-5n2gA: 12.90 2w98B-5n2gA: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6R_A_CTCA1385_0 (TETX2 PROTEIN)	1w27	PHENYLALANINE AMMONIA-LYASE 1 (Petroselinum crispum)	5 / 10	ASP A 205 ASN A 260 GLY A 398 PRO A 404 GLY A 494	MDO  A 203 ( 4.3A) DTT  A1717 (-2.8A) None None None	1.45A	2y6rA-1w27A: undetectable	2y6rA-1w27A: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVJ_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	3r6n	DESMOPLAKIN (Homo sapiens)	4 / 6	GLU A 293 TYR A 296 GLN A 318 ASP A 369	None None DTT  A   3 (-3.6A) None	1.36A	2zvjA-3r6nA: undetectable	2zvjA-3r6nA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5vzt	F-BOX ONLY PROTEIN 31 (Homo sapiens)	5 / 12	TYR B 509 VAL B 344 PHE B 491 PHE B 446 SER B 507	None None None None DTT  B 602 ( 4.9A)	1.44A	3apwA-5vztB: 3.4	3apwA-5vztB: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU9_B_SPMB700_1 (POLYAMINE OXIDASE)	1dk8	AXIN (Homo sapiens)	4 / 7	TYR A 119 TYR A 244 PHE A 238 TYR A 235	GOL  A 604 (-4.5A) None None DTT  A 701 (-4.3A)	1.37A	3ku9B-1dk8A: undetectable	3ku9B-1dk8A: 14.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NRR_A_D16A530_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.88A	3nrrA-5by6A: 14.7	3nrrA-5by6A: 33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NRR_B_D16B530_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASN A 106 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.93A	3nrrB-5by6A: 14.6	3nrrB-5by6A: 33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NRR_B_D16B530_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.88A	3nrrB-5by6A: 14.6	3nrrB-5by6A: 33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCB_A_017A201_1 (PROTEASE)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	5 / 12	GLY A 837 ALA A 851 ASP A 852 ILE A 915 VAL A 867	None None DTT  A1203 (-2.9A) None None	1.01A	3ucbA-3wzdA: undetectable	3ucbA-3wzdA: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UM5_A_CP6A609_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2czd	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (Pyrococcus horikoshii)	5 / 10	ILE A  54 VAL A  52 ILE A 183 ILE A  55 THR A  50	None None DTT  A 501 ( 4.6A) None None	1.06A	3um5A-2czdA: undetectable	3um5A-2czdA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UM5_B_CP6B709_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2czd	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (Pyrococcus horikoshii)	5 / 10	ILE A  54 VAL A  52 ILE A 183 ILE A  55 THR A  50	None None DTT  A 501 ( 4.6A) None None	1.11A	3um5B-2czdA: undetectable	3um5B-2czdA: 16.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UWL_B_FOZB316_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	ILE A 102 TRP A 103 LEU A 186 HIS A 190 GLY A 216 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.6A) UMP  A 401 (-3.5A) UMP  A 401 (-3.2A)	1.16A	3uwlB-5by6A: 35.8	3uwlB-5by6A: 42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UWL_D_FOZD316_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	TRP A 103 LEU A 186 LEU A 215 GLY A 216 ASN A 220	DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.5A) UMP  A 401 (-3.2A)	1.07A	3uwlD-5by6A: 34.9	3uwlD-5by6A: 42.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V1N_A_BEZA288_0 (2-HYDROXY-6-OXO-6-PH ENYLHEXA-2,4-DIENOAT E HYDROLASE)	1fx2	RECEPTOR-TYPE ADENYLATE CYCLASE GRESAG 4.1 (Trypanosoma brucei)	5 / 8	GLY A1061 GLY A1060 GLY A1018 ILE A 907 LEU A 913	DTT  A1124 ( 3.7A) None DTT  A1124 ( 4.4A) None None	1.15A	3v1nA-1fx2A: undetectable	3v1nA-1fx2A: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AF0_A_MOAA1526_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	5tqm	CINNAMOYL-COA REDUCTASE (Sorghum bicolor)	4 / 8	SER A 149 ASN A 209 ARG A 269 GLY A 186	DTT  A 403 ( 2.6A) None None None	0.99A	4af0A-5tqmA: undetectable	4af0A-5tqmA: 22.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_A_D16A402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 12	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.57A	4eb4A-5by6A: 41.7	4eb4A-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_B_D16B402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 12	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.62A	4eb4B-5by6A: 41.7	4eb4B-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 9	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.36A	4eb4C-5by6A: 42.4	4eb4C-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 10	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.41A	4eb4D-5by6A: 42.2	4eb4D-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	PHE A  74 ILE A 102 TRP A 103 PHE A 219 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A)	0.68A	4eb4D-5by6A: 42.2	4eb4D-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	ILE A 102 TRP A 103 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.09A	4fogA-5by6A: 36.1	4fogA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	ILE A 102 TRP A 103 LEU A 186 GLY A 216 PHE A 219	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A)	1.16A	4fogA-5by6A: 36.1	4fogA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	LYS A  71 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.09A	4fogA-5by6A: 36.1	4fogA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	LYS A  71 ILE A 102 TRP A 103 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.10A	4fogA-5by6A: 36.1	4fogA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_A_C2FA302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	LYS A  71 ILE A 102 TRP A 103 LEU A 186 GLY A 216	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.5A)	1.20A	4fogA-5by6A: 36.1	4fogA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_D_C2FD302_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 11	LYS A  71 ILE A 102 ASP A 212 LEU A 215 GLY A 216 TYR A 252	None DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.03A	4fogD-5by6A: 36.1	4fogD-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_A_D16A301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.83A	4foxA-5by6A: 36.2	4foxA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_A_D16A301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.16A	4foxA-5by6A: 36.2	4foxA-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_B_D16B302_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.79A	4foxB-5by6A: 36.2	4foxB-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_D_D16D301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.85A	4foxD-5by6A: 35.9	4foxD-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_E_D16E301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	LYS A  71 GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	None DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	1.14A	4foxE-5by6A: 36.2	4foxE-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_F_D16F301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.87A	4foxF-5by6A: 36.2	4foxF-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOX_G_D16G301_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) UMP  A 401 (-4.6A)	0.82A	4foxG-5by6A: 36.2	4foxG-5by6A: 45.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_B_D16B402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.44A	4iqqB-5by6A: 42.2	4iqqB-5by6A: 58.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.42A	4iqqC-5by6A: 42.7	4iqqC-5by6A: 58.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	1w27	PHENYLALANINE AMMONIA-LYASE 1 (Petroselinum crispum)	4 / 6	GLN A 488 THR A 114 HIS A 396 ASN A 260	MDO  A 203 ( 3.9A) None None DTT  A1717 (-2.8A)	1.26A	4pfjB-1w27A: undetectable	4pfjB-1w27A: 20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QRC_A_0LIA802_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	5 / 12	ALA A 866 GLU A 885 VAL A 916 LEU A1019 CYH A1024	LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) None DTT  A1202 (-2.0A)	0.49A	4qrcA-3wzdA: 28.9	4qrcA-3wzdA: 50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2czd	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (Pyrococcus horikoshii)	5 / 9	ALA A 174 ALA A 177 ILE A 183 GLY A 163 ALA A 161	None None DTT  A 501 ( 4.6A) None None	1.18A	4qvqK-2czdA: undetectable 4qvqL-2czdA: undetectable	4qvqK-2czdA: 20.43 4qvqL-2czdA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	2czd	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (Pyrococcus horikoshii)	5 / 9	ALA A 174 ALA A 177 ILE A 183 GLY A 163 ALA A 161	None None DTT  A 501 ( 4.6A) None None	1.18A	4qvqY-2czdA: undetectable 4qvqZ-2czdA: undetectable	4qvqY-2czdA: 20.43 4qvqZ-2czdA: 21.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4R7I_A_STIA1001_1 (MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	VAL A 848 ALA A 866 GLU A 885 CYH A 919 CYH A1024 LEU A1035	LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 (-4.1A) DTT  A1202 (-2.0A) LEV  A1201 (-4.8A)	0.59A	4r7iA-3wzdA: 34.8	4r7iA-3wzdA: 48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TYJ_A_0LIA801_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	ALA A 866 GLU A 885 ILE A 892 VAL A 916 CYH A1024 HIS A1026 LEU A1035	LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) None LEV  A1201 ( 4.6A) DTT  A1202 (-2.0A) None LEV  A1201 (-4.8A)	0.59A	4tyjA-3wzdA: 29.7	4tyjA-3wzdA: 51.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U0I_A_0LIA1001_2 (MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	ALA A 866 LEU A 889 CYH A 919 GLY A 922 CYH A1024 HIS A1026 LEU A1035 CYH A1045	LEV  A1201 (-3.5A) LEV  A1201 ( 4.4A) LEV  A1201 (-4.1A) LEV  A1201 (-3.6A) DTT  A1202 (-2.0A) None LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.53A	4u0iA-3wzdA: 35.3	4u0iA-3wzdA: 53.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	8 / 12	LEU A 840 ALA A 866 GLU A 885 VAL A 916 LEU A1019 CYH A1024 HIS A1026 LEU A1035	LEV  A1201 ( 3.8A) LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) None DTT  A1202 (-2.0A) None LEV  A1201 (-4.8A)	0.49A	4uxqA-3wzdA: 29.3	4uxqA-3wzdA: 52.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_A_0LIA1776_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 9	LEU A 840 VAL A 848 LYS A 868 CYH A1024 ARG A1027 LEU A1035	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) None DTT  A1202 (-2.0A) None LEV  A1201 (-4.8A)	1.08A	4v01A-3wzdA: 26.5	4v01A-3wzdA: 54.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V01_B_0LIB1770_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	ALA A 866 GLU A 885 VAL A 916 LEU A1019 CYH A1024 HIS A1026	LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) None DTT  A1202 (-2.0A) None	0.46A	4v01B-3wzdA: 26.6	4v01B-3wzdA: 54.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_A_0LIA1772_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	VAL A 848 ALA A 866 GLU A 885 VAL A 916 LEU A1019 CYH A1024 HIS A1026	LEV  A1201 ( 4.9A) LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) None DTT  A1202 (-2.0A) None	0.47A	4v04A-3wzdA: 34.6	4v04A-3wzdA: 54.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4V04_B_0LIB1771_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	ALA A 866 GLU A 885 VAL A 916 LEU A1019 CYH A1024 HIS A1026	LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) LEV  A1201 ( 4.6A) None DTT  A1202 (-2.0A) None	0.58A	4v04B-3wzdA: 29.4	4v04B-3wzdA: 54.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z69_A_DIFA1006_1 (SERUM ALBUMIN)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	4 / 7	ILE A1034 LEU A1029 GLY A1015 LYS A1014	None None None DTT  A1205 ( 4.3A)	1.03A	4z69A-3wzdA: undetectable	4z69A-3wzdA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_D_PAUD601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	3fve	DIAMINOPIMELATE EPIMERASE (Mycobacterium tuberculosis)	4 / 8	VAL A 134 GLY A 270 SER A 272 GLY A   8	None None None DTT  A 290 (-3.6A)	0.90A	5e26C-3fveA: undetectable 5e26D-3fveA: undetectable	5e26C-3fveA: 20.05 5e26D-3fveA: 20.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5FCT_A_C2FA402_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 TRP A 103 ASN A 106 LEU A 186	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None	0.83A	5fctA-5by6A: 42.1	5fctA-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5FCT_B_C2FB402_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	VAL A  73 PHE A  74 ILE A 102 TRP A 103 LEU A 186	None None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None	0.78A	5fctB-5by6A: 42.2	5fctB-5by6A: 63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H3A_A_D16A401_1 (ORF70)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 7	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.32A	5h3aA-5by6A: 42.9	5h3aA-5by6A: 60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H3A_B_D16B401_1 (ORF70)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 7	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.39A	5h3aB-5by6A: 42.9	5h3aB-5by6A: 60.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HI2_A_BAXA801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2czd	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (Pyrococcus horikoshii)	5 / 8	ILE A  25 VAL A   3 ILE A  70 ILE A  35 ASP A  57	None None None None DTT  A 501 ( 4.4A)	1.50A	5hi2A-2czdA: undetectable	5hi2A-2czdA: 20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_A_D16A402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.42A	5nooA-5by6A: 43.1	5nooA-5by6A: 58.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_B_D16B402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 7	ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.39A	5nooB-5by6A: 42.8	5nooB-5by6A: 58.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	4 / 6	ASP A 212 GLY A 216 PHE A 219 TYR A 252	None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.33A	5nooC-5by6A: 42.5	5nooC-5by6A: 58.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_C_CVIC301_1 (REGULATORY PROTEIN TETR)	5vzt	F-BOX ONLY PROTEIN 31 (Homo sapiens)	4 / 7	GLN B 535 GLY B 340 ILE B 337 TYR B 309	None None DTT  B 602 (-4.3A) DTT  B 602 ( 4.9A)	1.15A	5vlmC-5vztB: undetectable	5vlmC-5vztB: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_B_D16B402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	GLU A  81 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	DTT  A 402 (-3.0A) DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.55A	5x5qB-5by6A: 42.6	5x5qB-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 7	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.41A	5x5qC-5by6A: 43.0	5x5qC-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 8	LYS A  71 PHE A  74 ILE A 102 PHE A 219 TYR A 252	None None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.66A	5x5qD-5by6A: 43.0	5x5qD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 8	LYS A 300 PHE A  74 ILE A 102 PHE A 219 TYR A 252	None None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	1.20A	5x5qD-5by6A: 43.0	5x5qD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 8	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.48A	5x5qD-5by6A: 43.0	5x5qD-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_F_D16F402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 8	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.48A	5x5qF-5by6A: 42.9	5x5qF-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_A_MTXA402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	8 / 12	PHE A  74 ILE A 102 ASP A 212 LEU A 215 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.44A	5x66A-5by6A: 43.1 5x66B-5by6A: 13.1	5x66A-5by6A: 64.17 5x66B-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_C_MTXC402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 9	ILE A 102 ASP A 212 LEU A 215 GLY A 216 PHE A 219 ASN A 220 TYR A 252	DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.52A	5x66C-5by6A: 43.1	5x66C-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_D_MTXD402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	7 / 10	PHE A  74 ILE A 102 ASP A 212 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None DTT  A 402 ( 4.3A) None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	0.49A	5x66D-5by6A: 42.8	5x66D-5by6A: 64.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_F_MTXF402_1 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	8 / 12	LYS A  71 PHE A  74 ILE A 102 ASP A 212 LEU A 215 GLY A 216 PHE A 219 TYR A 252	None None DTT  A 402 ( 4.3A) None None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-4.6A)	0.90A	5x66F-5by6A: 42.8	5x66F-5by6A: 64.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IE8_A_CHDA201_0 (REGULATORY PROTEIN)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	5 / 12	LEU A 901 ILE A 888 ALA A 866 CYH A1024 LEU A1049	None LEV  A1201 (-3.9A) LEV  A1201 (-3.5A) DTT  A1202 (-2.0A) LEV  A1201 ( 4.5A)	1.11A	6ie8A-3wzdA: undetectable	6ie8A-3wzdA: 22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_A_FFOA403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	ILE A 102 TRP A 103 ASN A 106 LEU A 186 PHE A 219 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A)	1.24A	6r2eA-5by6A: 41.8	6r2eA-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_A_FFOA403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 12	PHE A  74 GLY A 216 PHE A 219 ASN A 220 TYR A 252	None UMP  A 401 (-3.5A) DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A) UMP  A 401 (-4.6A)	1.10A	6r2eA-5by6A: 41.8	6r2eA-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_A_FFOA403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	PHE A  74 ILE A 102 TRP A 103 ASN A 106 PHE A 219 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A)	1.17A	6r2eA-5by6A: 41.8	6r2eA-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_B_FFOB403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 TRP A 103 ASN A 106 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.85A	6r2eB-5by6A: 41.5	6r2eB-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_B_FFOB403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	PHE A  74 ILE A 102 TRP A 103 ASN A 106 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.2A)	0.76A	6r2eB-5by6A: 41.5	6r2eB-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_C_FFOC404_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 TRP A 103 ASN A 106 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	1.03A	6r2eC-5by6A: 41.8	6r2eC-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_C_FFOC404_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	PHE A  74 ILE A 102 TRP A 103 ASN A 106 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.2A)	0.85A	6r2eC-5by6A: 41.8	6r2eC-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_D_FFOD403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	ILE A 102 TRP A 103 ASN A 106 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.88A	6r2eD-5by6A: 41.5	6r2eD-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_D_FFOD403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 10	PHE A  74 ILE A 102 TRP A 103 ASN A 106 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.2A)	0.79A	6r2eD-5by6A: 41.5	6r2eD-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	ILE A 102 TRP A 103 ASN A 106 TYR A 129 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None None UMP  A 401 (-3.2A)	0.89A	6r2eE-5by6A: 41.6	6r2eE-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	PHE A  74 ILE A 102 TRP A 103 ASN A 106 PHE A 219 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A)	1.22A	6r2eE-5by6A: 41.6	6r2eE-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	PHE A  74 ILE A 102 TRP A 103 ASN A 106 TYR A 129 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.83A	6r2eE-5by6A: 41.6	6r2eE-5by6A: 61.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	5vzt	F-BOX ONLY PROTEIN 31 (Homo sapiens)	5 / 12	ILE B 337 TYR B 156 LEU B 269 GLY B 477 PHE B 478	DTT  B 602 (-4.3A) None None None None	0.97A	6r2eE-5vztB: undetectable	6r2eE-5vztB: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_F_FFOF403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	ILE A 102 TRP A 103 ASN A 106 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.97A	6r2eF-5by6A: 41.6	6r2eF-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_F_FFOF403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 TRP A 103 ASN A 106 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.2A)	0.79A	6r2eF-5by6A: 41.6	6r2eF-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_G_FFOG403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	ILE A 102 TRP A 103 ASN A 106 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.96A	6r2eG-5by6A: 41.7	6r2eG-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_G_FFOG403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 ASN A 106 PHE A 219 ASN A 220	None DTT  A 402 ( 4.3A) None DTT  A 402 ( 4.1A) UMP  A 401 (-3.2A)	1.24A	6r2eG-5by6A: 41.7	6r2eG-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_G_FFOG403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	5 / 11	PHE A  74 ILE A 102 TRP A 103 ASN A 106 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None UMP  A 401 (-3.2A)	0.82A	6r2eG-5by6A: 41.7	6r2eG-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_H_FFOH403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	ILE A 102 TRP A 103 ASN A 106 TYR A 129 LEU A 186 ASN A 220	DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None None UMP  A 401 (-3.2A)	0.71A	6r2eH-5by6A: 41.7	6r2eH-5by6A: 61.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_H_FFOH403_0 (THYMIDYLATE SYNTHASE)	5by6	THYMIDYLATE SYNTHASE (Trichinella spiralis)	6 / 12	PHE A  74 ILE A 102 TRP A 103 ASN A 106 TYR A 129 ASN A 220	None DTT  A 402 ( 4.3A) DTT  A 402 ( 4.1A) None None UMP  A 401 (-3.2A)	0.77A	6r2eH-5by6A: 41.7	6r2eH-5by6A: 61.66