SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DTR'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YVP_B_ACTB2002_0 (60-KDA SS-A/RO RIBONUCLEOPROTEIN)	4nap	EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7 (Desulfovibrio alaskensis)	4 / 6	SER A 212 ALA A 151 SER A 150 THR A 211	DTR A 401 (-3.3A) None DTR A 401 ( 4.6A) DTR A 401 (-3.0A)	1.21A	1yvpB-4napA: undetectable	1yvpB-4napA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NED_A_PFNA709_1 (LACTOTRANSFERRIN)	4nap	EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7 (Desulfovibrio alaskensis)	4 / 6	VAL A 215 ASP A 214 SER A 153 PHE A 148	None DTR A 401 (-3.3A) None None	1.18A	4nedA-4napA: 2.1	4nedA-4napA: 23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C6P_A_4YHA601_1 (PROTEIN C)	4nap	EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7 (Desulfovibrio alaskensis)	4 / 6	ALA A 120 SER A 124 GLN A 50 ASP A 214	None None None DTR A 401 (-3.3A)	1.22A	5c6pA-4napA: undetectable	5c6pA-4napA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U6M_A_SALA503_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	4nap	EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7 (Desulfovibrio alaskensis)	4 / 7	THR A 45 PHE A 238 MET A 219 THR A 211	DTR A 401 ( 3.7A) DTR A 401 (-4.7A) DTR A 401 ( 4.7A) DTR A 401 (-3.0A)	1.41A	5u6mA-4napA: undetectable	5u6mA-4napA: 21.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YVP_B_ACTB2002_0","60-KDA SS-A\/RO RIBONUCLEOPROTEIN","4nap","EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7","Desulfovibrio alaskensis",4,"SER A 212;ALA A 151;SER A 150;THR A 211","DTR A 401 (-3.3A);None;DTR A 401 ( 4.6A);DTR A 401 (-3.0A)","1.21A","1yvpB-4napA:undetectable",null],["4NED_A_PFNA709_1","LACTOTRANSFERRIN","4nap","EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7","Desulfovibrio alaskensis",4,"VAL A 215;ASP A 214;SER A 153;PHE A 148","None;DTR A 401 (-3.3A);None;None","1.18A","4nedA-4napA:2.1","1yvpB-4napA:21.01"],["5C6P_A_4YHA601_1","PROTEIN C","4nap","EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7","Desulfovibrio alaskensis",4,"ALA A 120;SER A 124;GLN A  50;ASP A 214","None;None;None;DTR A 401 (-3.3A)","1.22A","5c6pA-4napA:undetectable","4nedA-4napA:23.50"],["5U6M_A_SALA503_1","UDP-GLYCOSYLTRANSFERASE 74F2","4nap","EXTRACELLULAR SOLUTE-BINDING PROTEIN, FAMILY 7","Desulfovibrio alaskensis",4,"THR A  45;PHE A 238;MET A 219;THR A 211","DTR A 401 ( 3.7A);DTR A 401 (-4.7A);DTR A 401 ( 4.7A);DTR A 401 (-3.0A)","1.41A","5u6mA-4napA:undetectable","5c6pA-4napA:20.43"]]