SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DSB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Prosthecochloris
vibrioformis) 		4 / 7 TYR A 206
VAL A 278
THR A 265
GLY A 255
 DSB  A1330 (-4.0A)
DSB  A1330 (-3.6A)
None
None
 0.96A 3gssA-2c1hA:
undetectable		 3gssA-2c1hA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Prosthecochloris
vibrioformis) 		4 / 8 TYR A 276
PHE A 316
PHE A  84
ILE A 177
 DSB  A1330 (-3.9A)
None
None
None
 0.96A 4qoiA-2c1hA:
undetectable
4qoiB-2c1hA:
undetectable		 4qoiA-2c1hA:
22.94
4qoiB-2c1hA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 1eb3 5-AMINOLAEVULINIC
ACID DEHYDRATASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 185
ASP A 180
TYR A 207
 None
None
DSB  A1341 ( 4.5A)
 0.94A 4yo9B-1eb3A:
0.0		 4yo9B-1eb3A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2c1h DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Prosthecochloris
vibrioformis) 		3 / 3 ASP A  82
SER A 170
TYR A 197
 None
DSB  A1330 (-3.4A)
None
 0.89A 5glmA-2c1hA:
undetectable		 5glmA-2c1hA:
21.05