SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DQR'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AV2_C_DVAC6_0 (GRAMICIDIN A) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | ALA A 429VAL A 380TRP A 384 | NoneNoneDQR A 544 (-4.1A) | 0.85A | 1av2C-5g5zA:undetectable1av2D-5g5zA:undetectable | 1av2C-5g5zA:2.851av2D-5g5zA:2.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1NT6_A_DVAA6_0 (GRAMICIDIN C) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | ALA A 429VAL A 380TRP A 384 | NoneNoneDQR A 544 (-4.1A) | 0.81A | 1nt6A-5g5zA:undetectable | 1nt6A-5g5zA:2.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1NT6_B_DVAB6_0 (GRAMICIDIN C) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | ALA A 429VAL A 380TRP A 384 | NoneNoneDQR A 544 (-4.1A) | 0.81A | 1nt6B-5g5zA:undetectable | 1nt6B-5g5zA:2.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1V8B_A_ADNA502_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.39A | 1v8bA-3ldrA:undetectable | 1v8bA-3ldrA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1V8B_B_ADNB1502_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.38A | 1v8bB-3ldrA:undetectable | 1v8bB-3ldrA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1V8B_D_ADND3502_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.41A | 1v8bD-3ldrA:undetectable | 1v8bD-3ldrA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IZQ_B_DVAB6_0 (GRAMICIDIN D) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | TRP A 384ALA A 429VAL A 380 | DQR A 544 (-4.1A)NoneNone | 0.81A | 2izqA-5g5zA:undetectable2izqB-5g5zA:undetectable | 2izqA-5g5zA:2.852izqB-5g5zA:2.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2NXE_A_SAMA302_1 (RIBOSOMAL PROTEINL11METHYLTRANSFERASE) |
3ugg | SUCROSE:(SUCROSE/FRUCTAN)6-FRUCTOSYLTRANSFERASE (Pachysandraterminalis) | 3 / 3 | THR A 153ASP A 244SER A 242 | NoneDQR A 800 (-3.6A)None | 0.81A | 2nxeA-3uggA:undetectable | 2nxeA-3uggA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2RCT_A_RTLA140_1 (RETINOL-BINDINGPROTEIN II, CELLULAR) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | GLN A 378THR A 439TRP A 384 | NoneNoneDQR A 544 (-4.1A) | 1.13A | 2rctA-5g5zA:undetectable | 2rctA-5g5zA:13.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE) |
3ugg | SUCROSE:(SUCROSE/FRUCTAN)6-FRUCTOSYLTRANSFERASE (Pachysandraterminalis) | 5 / 12 | PHE A 47GLY A 94ALA A 122ASP A 33PRO A 37 | NoneNoneNoneDQR A 800 (-3.0A)None | 1.11A | 2zulA-3uggA:undetectable | 2zulA-3uggA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3HAM_B_LLLB500_1 (AMINOGLYCOSIDEPHOSPHOTRANSFERASE) |
3ugg | SUCROSE:(SUCROSE/FRUCTAN)6-FRUCTOSYLTRANSFERASE (Pachysandraterminalis) | 5 / 11 | ASP A 249CYH A 212ASP A 157SER A 93ASP A 33 | NoneNoneDQR A 800 (-3.1A)DQR A 800 (-3.0A)DQR A 800 (-3.0A) | 1.21A | 3hamB-3uggA:0.0 | 3hamB-3uggA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3L8L_A_DVAA6_0 (GRAMICIDIN D) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | ALA A 429VAL A 380TRP A 384 | NoneNoneDQR A 544 (-4.1A) | 0.84A | 3l8lA-5g5zA:undetectable3l8lB-5g5zA:undetectable | 3l8lA-5g5zA:2.853l8lB-5g5zA:3.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3N58_D_ADND500_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.38A | 3n58D-3ldrA:undetectable | 3n58D-3ldrA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3V8V_B_SAMB801_0 (RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE L) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 5 / 11 | GLY A 321ASP A 327VAL A 328ASN A 318LEU A 451 | NoneNoneNoneDQR A 544 (-3.1A)None | 1.14A | 3v8vB-5g5zA:undetectable | 3v8vB-5g5zA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZQ8_D_DVAD8_0 (VAL-GRAMICIDIN A) |
3ugg | SUCROSE:(SUCROSE/FRUCTAN)6-FRUCTOSYLTRANSFERASE (Pachysandraterminalis) | 3 / 3 | TRP A 30VAL A 91TRP A 57 | NoneNoneDQR A 800 ( 3.9A) | 1.18A | 3zq8C-3uggA:undetectable3zq8D-3uggA:undetectable | 3zq8C-3uggA:4.173zq8D-3uggA:4.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5M66_A_ADNA502_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.33A | 5m66A-3ldrA:undetectable | 5m66A-3ldrA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5UTU_F_ADNF503_1 (ADENOSYLHOMOCYSTEINASE) |
3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) | 5 / 12 | LEU A 78ASP A 60THR A 293LEU A 421HIS A 64 | NoneDQR A3168 (-2.5A)DQR A3168 ( 4.9A)NoneNone | 1.37A | 5utuF-3ldrA:undetectable | 5utuF-3ldrA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MN4_B_AM2B301_0 (AMINOGLYCOSIDEN(3)-ACETYLTRANSFERASE, AAC(3)-IVA) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 8 | TRP A 314HIS A 177GLU A 167GLU A 423 | DQR A 544 (-4.1A)DQR A 544 (-4.7A)DQR A 544 (-2.8A)DQR A 544 (-2.8A) | 1.14A | 6mn4B-5g5zA:undetectable | 6mn4B-5g5zA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MN4_F_AM2F301_0 (AMINOGLYCOSIDEN(3)-ACETYLTRANSFERASE, AAC(3)-IVA) |
5g5z | ABC TRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 7 | TRP A 314HIS A 177GLU A 167GLU A 423 | DQR A 544 (-4.1A)DQR A 544 (-4.7A)DQR A 544 (-2.8A)DQR A 544 (-2.8A) | 1.29A | 6mn4F-5g5zA:undetectable | 6mn4F-5g5zA:19.19 |