SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DPF'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AX9_A_EDRA999_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 4 / 8 | GLY A 136GLU A 217SER A 218HIS A 471 | DPF A 601 (-3.4A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)DPF A 601 (-4.2A) | 0.75A | 1ax9A-4fnmA:38.9 | 1ax9A-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DX6_A_GNTA602_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 12 | GLY A 135GLY A 136GLY A 137SER A 218PHE A 354HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 1.12A | 1dx6A-4fnmA:39.3 | 1dx6A-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DX6_A_GNTA602_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 7 / 12 | GLY A 135GLY A 136GLY A 137SER A 218TRP A 251PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)DPF A 601 ( 3.7A)NoneDPF A 601 (-4.2A) | 0.69A | 1dx6A-4fnmA:39.3 | 1dx6A-4fnmA:30.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1HTT_B_HISB450_0 (HISTIDYL-TRNASYNTHETASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLU A 142LEU A 475TYR A 457GLY A 136GLY A 141 | NoneNoneDPF A 601 (-3.2A)DPF A 601 (-3.4A)None | 1.28A | 1httB-4fnmA:undetectable | 1httB-4fnmA:22.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_A_DMEA998_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136GLU A 217SER A 218PHE A 309HIS A 471 | DPF A 601 (-3.4A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.73A | 1maaA-4fnmA:38.2 | 1maaA-4fnmA:30.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_C_DMEC997_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136TYR A 132SER A 218PHE A 309HIS A 471 | DPF A 601 (-3.4A)NoneDPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 1.21A | 1maaC-4fnmA:38.2 | 1maaC-4fnmA:30.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_C_DMEC997_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136TYR A 132SER A 218PHE A 354HIS A 471 | DPF A 601 (-3.4A)NoneDPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 1.21A | 1maaC-4fnmA:38.2 | 1maaC-4fnmA:30.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_C_DMEC997_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136TYR A 148SER A 218PHE A 309HIS A 471 | DPF A 601 (-3.4A)NoneDPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.83A | 1maaC-4fnmA:38.2 | 1maaC-4fnmA:30.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_D_DMED999_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 4 / 8 | GLY A 136GLU A 217SER A 218HIS A 471 | DPF A 601 (-3.4A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)DPF A 601 (-4.2A) | 0.38A | 1maaD-4fnmA:38.2 | 1maaD-4fnmA:30.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1MAA_D_DMED999_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 4 / 8 | GLY A 137GLU A 217SER A 218HIS A 471 | DPF A 601 (-3.7A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)DPF A 601 (-4.2A) | 0.80A | 1maaD-4fnmA:38.2 | 1maaD-4fnmA:30.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MX1_D_THAD4_1 (LIVERCARBOXYLESTERASE I) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136GLY A 137SER A 218PHE A 421HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.56A | 1mx1D-4fnmA:37.5 | 1mx1D-4fnmA:29.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MX1_F_THAF6_1 (LIVERCARBOXYLESTERASE I) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 136GLY A 137SER A 218PHE A 421HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.48A | 1mx1F-4fnmA:37.3 | 1mx1F-4fnmA:29.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1QTI_A_GNTA600_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 7 / 12 | GLY A 135GLY A 136GLY A 137GLU A 217SER A 218PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.52A | 1qtiA-4fnmA:38.6 | 1qtiA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1QTI_A_GNTA600_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 12 | GLY A 135GLY A 136GLY A 137SER A 218PHE A 354HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 1.08A | 1qtiA-4fnmA:38.6 | 1qtiA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1W6R_A_GNTA1536_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | GLY A 135GLY A 136GLY A 137PHE A 309PHE A 354 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)NoneNone | 0.72A | 1w6rA-4fnmA:39.2 | 1w6rA-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1W6R_A_GNTA1536_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 12 | GLY A 135GLY A 136GLY A 137SER A 218PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.61A | 1w6rA-4fnmA:39.2 | 1w6rA-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1W76_A_GNTA1538_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 11 | GLY A 136GLY A 137GLU A 217SER A 218PHE A 309HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.55A | 1w76A-4fnmA:38.5 | 1w76A-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1W76_B_GNTB1538_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 10 | GLY A 135GLY A 136GLU A 217SER A 218PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.52A | 1w76B-4fnmA:38.5 | 1w76B-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1W76_B_GNTB1538_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 10 | GLY A 135GLY A 136SER A 218PHE A 354HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 1.01A | 1w76B-4fnmA:38.5 | 1w76B-4fnmA:30.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ACE_A_ACHA998_0 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 9 | GLY A 135GLY A 136SER A 218ALA A 219HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-1.5A)DPF A 601 (-3.3A)DPF A 601 (-4.2A) | 0.87A | 2aceA-4fnmA:10.7 | 2aceA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ACE_A_ACHA998_0 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 9 | GLY A 136GLY A 137ALA A 219TRP A 251PHE A 309PHE A 3 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-3.3A)DPF A 601 ( 3.7A)NoneNone | 1.37A | 2aceA-4fnmA:10.7 | 2aceA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ACE_A_ACHA998_0 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 7 / 9 | GLY A 136GLY A 137SER A 218ALA A 219TRP A 251PHE A 309HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)DPF A 601 (-3.3A)DPF A 601 ( 3.7A)NoneDPF A 601 (-4.2A) | 0.72A | 2aceA-4fnmA:10.7 | 2aceA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ACK_A_EDRA999_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 4 / 7 | GLY A 136GLU A 217SER A 218HIS A 471 | DPF A 601 (-3.4A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)DPF A 601 (-4.2A) | 0.82A | 2ackA-4fnmA:39.0 | 2ackA-4fnmA:30.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HA4_A_ACTA544_0 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 8 | GLY A 136GLY A 137ALA A 219TRP A 251PHE A 309HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-3.3A)DPF A 601 ( 3.7A)NoneDPF A 601 (-4.2A) | 0.78A | 2ha4A-4fnmA:38.3 | 2ha4A-4fnmA:30.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HA4_B_ACTB601_0 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 7 | GLY A 136GLY A 137ALA A 219TRP A 251PHE A 309HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-3.3A)DPF A 601 ( 3.7A)NoneDPF A 601 (-4.2A) | 0.79A | 2ha4B-4fnmA:38.7 | 2ha4B-4fnmA:30.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BXO_A_SAMA238_1 (N,N-DIMETHYLTRANSFERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 3 / 3 | TYR A 165GLU A 217ASP A 473 | NoneDPF A 601 ( 4.2A)None | 0.77A | 3bxoA-4fnmA:undetectable | 3bxoA-4fnmA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BXO_B_SAMB238_1 (N,N-DIMETHYLTRANSFERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 3 / 3 | TYR A 165GLU A 217ASP A 473 | NoneDPF A 601 ( 4.2A)None | 0.79A | 3bxoB-4fnmA:undetectable | 3bxoB-4fnmA:17.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3O9M_A_BEZA999_0 (CHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 7 | GLY A 136GLY A 137SER A 218TRP A 251PHE A 421HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)DPF A 601 ( 3.7A)NoneDPF A 601 (-4.2A) | 0.66A | 3o9mA-4fnmA:38.7 | 3o9mA-4fnmA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3O9M_B_BEZB999_0 (CHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 6 | GLY A 136GLY A 137SER A 218TRP A 251HIS A 471 | DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)DPF A 601 ( 3.7A)DPF A 601 (-4.2A) | 0.43A | 3o9mB-4fnmA:38.9 | 3o9mB-4fnmA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4EY6_A_GNTA604_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 12 | GLY A 135GLY A 136GLY A 137SER A 218PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.54A | 4ey6A-4fnmA:38.7 | 4ey6A-4fnmA:30.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4EY6_B_GNTB605_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 6 / 12 | GLY A 135GLY A 136GLY A 137GLU A 217PHE A 354HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 ( 4.2A)NoneDPF A 601 (-4.2A) | 1.12A | 4ey6B-4fnmA:38.3 | 4ey6B-4fnmA:30.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4EY6_B_GNTB605_1 (ACETYLCHOLINESTERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 7 / 12 | GLY A 135GLY A 136GLY A 137GLU A 217SER A 218PHE A 309HIS A 471 | DPF A 601 ( 3.8A)DPF A 601 (-3.4A)DPF A 601 (-3.7A)DPF A 601 ( 4.2A)DPF A 601 (-1.5A)NoneDPF A 601 (-4.2A) | 0.52A | 4ey6B-4fnmA:38.3 | 4ey6B-4fnmA:30.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LS7_B_1X9B503_1 (3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | MET A 227ALA A 221PHE A 138HIS A 471GLY A 245 | NoneNoneNoneDPF A 601 (-4.2A)None | 1.02A | 4ls7A-4fnmA:undetectable4ls7B-4fnmA:undetectable | 4ls7A-4fnmA:21.334ls7B-4fnmA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LS7_B_1X9B503_1 (3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | MET A 227ILE A 133ALA A 221PHE A 138HIS A 471 | NoneNoneNoneNoneDPF A 601 (-4.2A) | 1.07A | 4ls7A-4fnmA:undetectable4ls7B-4fnmA:undetectable | 4ls7A-4fnmA:21.334ls7B-4fnmA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XUE_A_SAMA303_1 (CATECHOLO-METHYLTRANSFERASE) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 4 / 5 | GLY A 135TYR A 226SER A 223GLU A 217 | DPF A 601 ( 3.8A)NoneNoneDPF A 601 ( 4.2A) | 1.18A | 4xueA-4fnmA:2.2 | 4xueA-4fnmA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XXI_A_LSNA501_1 (CYTOCHROME P450 2C9) |
4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Luciliacuprina) | 5 / 12 | ALA A 194GLN A 164GLY A 220ALA A 219LEU A 167 | NoneNoneNoneDPF A 601 (-3.3A)None | 1.07A | 5xxiA-4fnmA:undetectable | 5xxiA-4fnmA:20.50 |