SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DO2'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 THR A1102
GLY A1099
VAL A1122
ALA A1037
ALA A1036
 None
DO2  A4000 (-3.5A)
None
None
DO2  A4000 ( 4.0A)
 1.06A 1nw5A-1djpA:
undetectable		 1nw5A-1djpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 7 GLU A1104
THR A1020
ASN A1176
SER A1067
 None
DO2  A4000 (-2.1A)
None
DO2  A4000 (-2.4A)
 1.13A 4pfjA-1djpA:
2.9		 4pfjA-1djpA:
25.11