SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DMX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 1tp7 GENOME POLYPROTEIN
(Rhinovirus
A) 		4 / 5 ASP A 357
ASP A 366
PHE A 377
GLY A 368
 None
DMX  A 500 (-4.1A)
None
DMX  A 500 ( 4.7A)
 1.23A 4xp6A-1tp7A:
0.0		 4xp6A-1tp7A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 4c4a PROTEIN ARGININE
N-METHYLTRANSFERASE
7
(Mus
musculus) 		3 / 3 ARG A 458
TYR A 495
GLU A 460
 DMX  A2690 (-3.1A)
DMX  A2690 ( 4.4A)
None
 0.71A 4zzbE-4c4aA:
undetectable		 4zzbE-4c4aA:
18.41