SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DMN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5lti HEME DEPENDENT
OXIDATIVE
N-DEMETHYLASE
(Pseudomonas
mendocina) 		5 / 11 VAL A 197
ALA A 178
GLU A 266
ILE A 283
ASP A 156
 HEM  A 501 (-4.2A)
DMN  A 502 ( 4.4A)
DMN  A 502 (-2.9A)
DMN  A 502 ( 4.7A)
None
 1.30A 2admB-5ltiA:
undetectable		 2admB-5ltiA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 5lti HEME DEPENDENT
OXIDATIVE
N-DEMETHYLASE
(Pseudomonas
mendocina) 		5 / 11 ALA A 178
GLY A 319
ILE A 320
PRO A 198
VAL A 197
 DMN  A 502 ( 4.4A)
None
None
None
HEM  A 501 (-4.2A)
 1.04A 3el1A-5ltiA:
undetectable		 3el1A-5ltiA:
13.65