SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DMA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 4gp1 POLYPRENYL
SYNTHETASE
(Pyrobaculum
calidifontis) 		4 / 6 HIS A  78
ILE A  77
ALA A 123
VAL A 137
 DMA  A 402 (-3.9A)
None
None
None
 0.90A 1hk1A-4gp1A:
2.2		 1hk1A-4gp1A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 5 ILE A 191
ARG A  50
ASP A 229
ASN A 255
 None
DMA  A 500 (-3.1A)
None
None
 1.33A 1kiaD-3q1oA:
0.0		 1kiaD-3q1oA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 12 GLY A 215
PHE A 218
LEU A 286
ILE A 185
LEU A  50
 None
DMA  A 299 (-3.7A)
None
DMA  A 299 (-4.4A)
None
 1.03A 1lhuA-3p41A:
undetectable		 1lhuA-3p41A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 4 ILE A 191
ARG A  50
ASP A 229
ASN A 255
 None
DMA  A 500 (-3.1A)
None
None
 1.43A 1nbiC-3q1oA:
0.0		 1nbiC-3q1oA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 4 ILE A 191
ARG A  50
ASP A 229
ASN A 255
 None
DMA  A 500 (-3.1A)
None
None
 1.45A 1nbiD-3q1oA:
0.0		 1nbiD-3q1oA:
21.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		8 / 11 SER A  79
LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 DMA  A 300 (-3.7A)
None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.39A 1rqjA-3p41A:
36.5		 1rqjA-3p41A:
50.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		11 / 11 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.40A 1rqjA-3q1oA:
35.1		 1rqjA-3q1oA:
34.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.38A 1rqjA-3qqvA:
33.5		 1rqjA-3qqvA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.80A 1rqjA-3qqvA:
33.5		 1rqjA-3qqvA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.66A 1rqjA-3qqvA:
33.5		 1rqjA-3qqvA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		8 / 11 SER A  79
LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 DMA  A 300 (-3.7A)
None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.37A 1rqjB-3p41A:
36.2		 1rqjB-3p41A:
50.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 11 SER A  79
LEU A  80
LYS A 180
THR A 181
GLN A 219
 DMA  A 300 (-3.7A)
None
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.96A 1rqjB-3p41A:
36.2		 1rqjB-3p41A:
50.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		11 / 11 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.39A 1rqjB-3q1oA:
35.1		 1rqjB-3q1oA:
34.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.37A 1rqjB-3qqvA:
33.7		 1rqjB-3qqvA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.76A 1rqjB-3qqvA:
33.7		 1rqjB-3qqvA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.63A 1rqjB-3qqvA:
33.7		 1rqjB-3qqvA:
31.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4gp1 POLYPRENYL
SYNTHETASE
(Pyrobaculum
calidifontis) 		3 / 3 ASP A 226
GLU A 148
ARG A  49
 None
None
DMA  A 402 (-3.1A)
 0.83A 1wopA-4gp1A:
undetectable		 1wopA-4gp1A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 11 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.52A 1yhlA-3p41A:
24.4		 1yhlA-3p41A:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 11 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.50A 1yhlA-3q1oA:
30.3		 1yhlA-3q1oA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.37A 1yhlA-3qqvA:
33.6		 1yhlA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 1.05A 1yhlA-3qqvA:
33.6		 1yhlA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.77A 1yhlA-3qqvA:
33.6		 1yhlA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.61A 1yhlA-3qqvA:
33.6		 1yhlA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 11 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.53A 1yq7A-3p41A:
23.3		 1yq7A-3p41A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 11 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 1yq7A-3q1oA:
30.9		 1yq7A-3q1oA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.29A 1yq7A-3qqvA:
33.1		 1yq7A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 1.01A 1yq7A-3qqvA:
33.1		 1yq7A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.65A 1yq7A-3qqvA:
33.1		 1yq7A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.49A 1yv5A-3p41A:
23.4		 1yv5A-3p41A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.18A 1yv5A-3q1oA:
31.0		 1yv5A-3q1oA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 1yv5A-3q1oA:
31.0		 1yv5A-3q1oA:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.41A 1yv5A-3qqvA:
33.3		 1yv5A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.73A 1yv5A-3qqvA:
33.3		 1yv5A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.58A 1yv5A-3qqvA:
33.3		 1yv5A-3qqvA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.56A 1zw5A-3p41A:
23.9		 1zw5A-3p41A:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 1zw5A-3q1oA:
31.3		 1zw5A-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.18A 1zw5A-3q1oA:
31.3		 1zw5A-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.44A 1zw5A-3qqvA:
33.2		 1zw5A-3qqvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.82A 1zw5A-3qqvA:
33.2		 1zw5A-3qqvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.60A 1zw5A-3qqvA:
33.2		 1zw5A-3qqvA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2ick ISOPENTENYL-DIPHOSPH
ATE DELTA ISOMERASE
(Homo
sapiens) 		4 / 7 ARG A  71
SER A  72
GLN A  14
GLU A 168
 DMA  A 301 (-2.6A)
None
DMA  A 301 ( 4.7A)
DMA  A 301 ( 4.7A)
 0.98A 2c8aA-2ickA:
undetectable		 2c8aA-2ickA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.53A 2e91A-3p41A:
19.5		 2e91A-3p41A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
 0.52A 2e91A-3q1oA:
20.7		 2e91A-3q1oA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 281
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 (-2.4A)
 1.21A 2e91A-3qqvA:
25.5		 2e91A-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.91A 2e91A-3qqvA:
25.5		 2e91A-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.64A 2e91A-3qqvA:
25.5		 2e91A-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.72A 2e91B-3p41A:
18.4		 2e91B-3p41A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
 0.69A 2e91B-3q1oA:
19.9		 2e91B-3q1oA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 281
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 (-2.4A)
 1.28A 2e91B-3qqvA:
24.4		 2e91B-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.95A 2e91B-3qqvA:
24.4		 2e91B-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.66A 2e91B-3qqvA:
24.4		 2e91B-3qqvA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 345
TYR A 245
ILE A 221
SER A 368
ILE A  65
 None
None
None
None
DMA  A 383 (-4.7A)
 1.35A 2efjA-3qqvA:
undetectable		 2efjA-3qqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 9 ASP A  83
ASP A  89
ARG A  94
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
 0.45A 2f89F-3p41A:
24.5		 2f89F-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 ASP A  92
ASP A  98
ARG A 103
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.40A 2f89F-3q1oA:
31.6		 2f89F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.18A 2f89F-3q1oA:
31.6		 2f89F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.51A 2f89F-3qqvA:
34.4		 2f89F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
TYR A 219
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.78A 2f89F-3qqvA:
34.4		 2f89F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 11 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.54A 2f8cF-3p41A:
24.3		 2f8cF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 11 LEU A  80
GLN A 157
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.96A 2f8cF-3p41A:
24.3		 2f8cF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 11 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.17A 2f8cF-3q1oA:
31.4		 2f8cF-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 11 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 2f8cF-3q1oA:
31.4		 2f8cF-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.33A 2f8cF-3qqvA:
34.1		 2f8cF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.81A 2f8cF-3qqvA:
34.1		 2f8cF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.94A 2f8cF-3qqvA:
34.1		 2f8cF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.59A 2f8cF-3qqvA:
34.1		 2f8cF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.51A 2f8zF-3p41A:
24.5		 2f8zF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 LEU A  80
GLN A 157
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.96A 2f8zF-3p41A:
24.5		 2f8zF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.15A 2f8zF-3q1oA:
31.5		 2f8zF-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 2f8zF-3q1oA:
31.5		 2f8zF-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.47A 2f8zF-3qqvA:
34.2		 2f8zF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.78A 2f8zF-3qqvA:
34.2		 2f8zF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.59A 2f8zF-3qqvA:
34.2		 2f8zF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 12 LEU A  80
ARG A  94
GLN A 157
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 1.07A 2f94F-3p41A:
24.0		 2f94F-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 12 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.75A 2f94F-3p41A:
24.0		 2f94F-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 12 LEU A  89
ASP A  92
ASP A  98
ARG A 103
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 2f94F-3q1oA:
31.1		 2f94F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 12 LEU A  89
ASP A  92
ASP A  98
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.67A 2f94F-3q1oA:
31.1		 2f94F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ARG A 117
GLN A 191
LYS A 215
THR A 216
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.35A 2f94F-3qqvA:
33.8		 2f94F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.89A 2f94F-3qqvA:
33.8		 2f94F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.47A 2f94F-3qqvA:
33.8		 2f94F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.70A 2f94F-3qqvA:
33.8		 2f94F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.51A 2f9kF-3p41A:
24.1		 2f9kF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 LEU A  80
GLN A 157
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.97A 2f9kF-3p41A:
24.1		 2f9kF-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 2f9kF-3q1oA:
31.3		 2f9kF-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.43A 2f9kF-3qqvA:
33.7		 2f9kF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.79A 2f9kF-3qqvA:
33.7		 2f9kF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.60A 2f9kF-3qqvA:
33.7		 2f9kF-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.47A 2o1oA-3p41A:
22.8		 2o1oA-3p41A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
 0.48A 2o1oA-3q1oA:
27.4		 2o1oA-3q1oA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 383 ( 4.0A)
 0.86A 2o1oA-3qqvA:
29.1		 2o1oA-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.65A 2o1oA-3qqvA:
29.1		 2o1oA-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.63A 2o1oB-3p41A:
23.5		 2o1oB-3p41A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
 0.46A 2o1oB-3q1oA:
28.1		 2o1oB-3q1oA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.88A 2o1oB-3qqvA:
29.9		 2o1oB-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.74A 2o1oB-3qqvA:
29.9		 2o1oB-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.71A 2q58A-3p41A:
23.1		 2q58A-3p41A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 10 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 229
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
None
 0.54A 2q58A-3q1oA:
27.8		 2q58A-3q1oA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 10 LEU A  89
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 229
 DMA  A 501 ( 4.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
None
 0.63A 2q58A-3q1oA:
27.8		 2q58A-3q1oA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
ASP A 258
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
None
 0.85A 2q58A-3qqvA:
29.2		 2q58A-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.95A 2q58A-3qqvA:
29.2		 2q58A-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.88A 2q58A-3qqvA:
29.2		 2q58A-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.63A 2q58B-3p41A:
23.1		 2q58B-3p41A:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
 0.50A 2q58B-3q1oA:
27.3		 2q58B-3q1oA:
28.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.87A 2q58B-3qqvA:
29.7		 2q58B-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.77A 2q58B-3qqvA:
29.7		 2q58B-3qqvA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.39A 2qisA-3p41A:
23.9		 2qisA-3p41A:
28.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.21A 2qisA-3q1oA:
31.2		 2qisA-3q1oA:
27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.49A 2qisA-3q1oA:
31.2		 2qisA-3q1oA:
27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.36A 2qisA-3qqvA:
33.6		 2qisA-3qqvA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.76A 2qisA-3qqvA:
33.6		 2qisA-3qqvA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.53A 2qisA-3qqvA:
33.6		 2qisA-3qqvA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.58A 3ez3A-3p41A:
23.8		 3ez3A-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 3ez3A-3q1oA:
31.0		 3ez3A-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.97A 3ez3A-3qqvA:
32.5		 3ez3A-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.73A 3ez3A-3qqvA:
32.5		 3ez3A-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.50A 3ez3B-3p41A:
23.3		 3ez3B-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.45A 3ez3B-3q1oA:
30.3		 3ez3B-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.87A 3ez3B-3qqvA:
32.1		 3ez3B-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.65A 3ez3B-3qqvA:
32.1		 3ez3B-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.59A 3ez3C-3p41A:
23.8		 3ez3C-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 3ez3C-3q1oA:
30.9		 3ez3C-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.96A 3ez3C-3qqvA:
32.5		 3ez3C-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.76A 3ez3C-3qqvA:
32.5		 3ez3C-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.52A 3ez3D-3p41A:
23.5		 3ez3D-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.45A 3ez3D-3q1oA:
29.9		 3ez3D-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 ( 2.8A)
 1.41A 3ez3D-3qqvA:
31.8		 3ez3D-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.37A 3ez3D-3qqvA:
31.8		 3ez3D-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.75A 3ez3D-3qqvA:
31.8		 3ez3D-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.63A 3ez3D-3qqvA:
31.8		 3ez3D-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 ARG A  94
GLN A 157
LYS A 180
THR A 181
GLN A 219
 DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 1.02A 3ibaA-3p41A:
24.3		 3ibaA-3p41A:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 10 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.48A 3ibaA-3p41A:
24.3		 3ibaA-3p41A:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 10 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.50A 3ibaA-3q1oA:
30.2		 3ibaA-3q1oA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 108
ARG A 117
GLN A 191
LYS A 215
THR A 216
LYS A 271
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 384 ( 2.8A)
 1.38A 3ibaA-3qqvA:
33.4		 3ibaA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.83A 3ibaA-3qqvA:
33.4		 3ibaA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 1.03A 3ibaA-3qqvA:
33.4		 3ibaA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.63A 3ibaA-3qqvA:
33.4		 3ibaA-3qqvA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 SER A 368
ARG A 372
ARG A 117
GLY A  62
 None
None
DMA  A 384 (-3.0A)
DMA  A 383 (-3.3A)
 1.25A 3k9fA-3qqvA:
undetectable
3k9fB-3qqvA:
undetectable
3k9fC-3qqvA:
undetectable		 3k9fA-3qqvA:
23.43
3k9fB-3qqvA:
23.43
3k9fC-3qqvA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.59A 3ldwA-3p41A:
23.7		 3ldwA-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.49A 3ldwA-3q1oA:
30.9		 3ldwA-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.98A 3ldwA-3qqvA:
32.3		 3ldwA-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.75A 3ldwA-3qqvA:
32.3		 3ldwA-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.53A 3ldwB-3p41A:
23.3		 3ldwB-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 3ldwB-3q1oA:
30.2		 3ldwB-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.49A 3ldwB-3qqvA:
32.1		 3ldwB-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.87A 3ldwB-3qqvA:
32.1		 3ldwB-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.67A 3ldwB-3qqvA:
32.1		 3ldwB-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.59A 3ldwC-3p41A:
23.4		 3ldwC-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 3ldwC-3q1oA:
30.8		 3ldwC-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.96A 3ldwC-3qqvA:
32.3		 3ldwC-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.75A 3ldwC-3qqvA:
32.3		 3ldwC-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.54A 3ldwD-3p41A:
23.1		 3ldwD-3p41A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.46A 3ldwD-3q1oA:
29.9		 3ldwD-3q1oA:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.48A 3ldwD-3qqvA:
31.8		 3ldwD-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.88A 3ldwD-3qqvA:
31.8		 3ldwD-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.68A 3ldwD-3qqvA:
31.8		 3ldwD-3qqvA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 8 HIS A 124
SER A 114
ASP A 276
ASP A 108
 None
MG  A 382 ( 4.6A)
DMA  A 384 ( 4.8A)
MG  A 381 (-2.4A)
 1.22A 3n2oC-3qqvA:
4.9
3n2oD-3qqvA:
4.7		 3n2oC-3qqvA:
22.78
3n2oD-3qqvA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 11 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.52A 3n45F-3p41A:
24.1		 3n45F-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 11 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.20A 3n45F-3q1oA:
31.5		 3n45F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 11 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 3n45F-3q1oA:
31.5		 3n45F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.33A 3n45F-3qqvA:
33.9		 3n45F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 1.02A 3n45F-3qqvA:
33.9		 3n45F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.75A 3n45F-3qqvA:
33.9		 3n45F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.62A 3n45F-3qqvA:
33.9		 3n45F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.53A 3n46F-3p41A:
24.2		 3n46F-3p41A:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.50A 3n46F-3q1oA:
31.2		 3n46F-3q1oA:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.33A 3n46F-3qqvA:
33.9		 3n46F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.75A 3n46F-3qqvA:
33.9		 3n46F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.61A 3n46F-3qqvA:
33.9		 3n46F-3qqvA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 12 LEU A  89
PHE A  39
GLY A  46
GLU A  82
PHE A  16
 DMA  A 501 ( 4.8A)
None
DMA  A 500 (-3.4A)
DMA  A 500 ( 4.6A)
None
 1.27A 3tbgC-3q1oA:
undetectable		 3tbgC-3q1oA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.37A 4kfaA-3p41A:
23.6		 4kfaA-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 4kfaA-3q1oA:
31.0		 4kfaA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.39A 4kfaA-3qqvA:
33.3		 4kfaA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.34A 4kfaA-3qqvA:
33.3		 4kfaA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.74A 4kfaA-3qqvA:
33.3		 4kfaA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.57A 4kfaA-3qqvA:
33.3		 4kfaA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.47A 4kpdA-3p41A:
24.3		 4kpdA-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.44A 4kpdA-3q1oA:
31.4		 4kpdA-3q1oA:
27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.35A 4kpdA-3qqvA:
34.1		 4kpdA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.79A 4kpdA-3qqvA:
34.1		 4kpdA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.56A 4kpdA-3qqvA:
34.1		 4kpdA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
 0.51A 4kpjA-3p41A:
23.6		 4kpjA-3p41A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.27A 4kpjA-3q1oA:
31.0		 4kpjA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 4kpjA-3q1oA:
31.0		 4kpjA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.31A 4kpjA-3qqvA:
33.3		 4kpjA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.61A 4kpjA-3qqvA:
33.3		 4kpjA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.49A 4kq5A-3p41A:
23.6		 4kq5A-3p41A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 4kq5A-3q1oA:
31.1		 4kq5A-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.50A 4kq5A-3qqvA:
33.3		 4kq5A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.78A 4kq5A-3qqvA:
33.3		 4kq5A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.65A 4kq5A-3qqvA:
33.3		 4kq5A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.48A 4kqsA-3p41A:
24.5		 4kqsA-3p41A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.23A 4kqsA-3q1oA:
31.4		 4kqsA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 4kqsA-3q1oA:
31.4		 4kqsA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.36A 4kqsA-3qqvA:
33.8		 4kqsA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.77A 4kqsA-3qqvA:
33.8		 4kqsA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.58A 4kqsA-3qqvA:
33.8		 4kqsA-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
None
 0.55A 4n9uA-3p41A:
23.6		 4n9uA-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
None
 1.28A 4n9uA-3p41A:
23.6		 4n9uA-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.22A 4n9uA-3q1oA:
31.1		 4n9uA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 4n9uA-3q1oA:
31.1		 4n9uA-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.73A 4n9uA-3qqvA:
33.5		 4n9uA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 1.43A 4n9uA-3qqvA:
33.5		 4n9uA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.61A 4n9uA-3qqvA:
33.5		 4n9uA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 12 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
None
 0.74A 4ng6A-3p41A:
24.1		 4ng6A-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 12 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.24A 4ng6A-3q1oA:
31.1		 4ng6A-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 12 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.67A 4ng6A-3q1oA:
31.1		 4ng6A-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 383 ( 4.0A)
 0.99A 4ng6A-3qqvA:
33.6		 4ng6A-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 1.40A 4ng6A-3qqvA:
33.6		 4ng6A-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.51A 4ng6A-3qqvA:
33.6		 4ng6A-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.66A 4ng6A-3qqvA:
33.6		 4ng6A-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.51A 4nkeA-3p41A:
24.0		 4nkeA-3p41A:
28.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.22A 4nkeA-3q1oA:
31.0		 4nkeA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.59A 4nkeA-3q1oA:
31.0		 4nkeA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.24A 4nkeA-3qqvA:
33.5		 4nkeA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ARG A 117
LYS A 215
THR A 216
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.06A 4nkeA-3qqvA:
33.5		 4nkeA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.78A 4nkeA-3qqvA:
33.5		 4nkeA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.57A 4nkeA-3qqvA:
33.5		 4nkeA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 9 LEU A  80
ARG A  94
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.95A 4nkfA-3p41A:
23.9		 4nkfA-3p41A:
28.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
 0.58A 4nkfA-3p41A:
23.9		 4nkfA-3p41A:
28.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.26A 4nkfA-3q1oA:
31.0		 4nkfA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.51A 4nkfA-3q1oA:
31.0		 4nkfA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 LEU A 105
ASP A 108
ARG A 117
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.30A 4nkfA-3qqvA:
33.5		 4nkfA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.65A 4nkfA-3qqvA:
33.5		 4nkfA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.50A 4nuaA-3p41A:
24.0		 4nuaA-3p41A:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.28A 4nuaA-3q1oA:
31.1		 4nuaA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.64A 4nuaA-3q1oA:
31.1		 4nuaA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.05A 4nuaA-3qqvA:
33.8		 4nuaA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ARG A 117
LYS A 215
THR A 216
GLN A 254
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 0.91A 4nuaA-3qqvA:
33.8		 4nuaA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.78A 4nuaA-3qqvA:
33.8		 4nuaA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.58A 4nuaA-3qqvA:
33.8		 4nuaA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
 0.56A 4oguA-3p41A:
23.8		 4oguA-3p41A:
28.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.24A 4oguA-3q1oA:
30.9		 4oguA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.47A 4oguA-3q1oA:
30.9		 4oguA-3q1oA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 9 LEU A 105
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.42A 4oguA-3qqvA:
33.4		 4oguA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.60A 4oguA-3qqvA:
33.4		 4oguA-3qqvA:
28.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 9 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.55A 4p0vA-3p41A:
24.3		 4p0vA-3p41A:
27.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 9 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 4p0vA-3q1oA:
31.4		 4p0vA-3q1oA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.88A 4p0vA-3qqvA:
34.0		 4p0vA-3qqvA:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.64A 4p0vA-3qqvA:
34.0		 4p0vA-3qqvA:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 11 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.55A 4p0wA-3p41A:
24.2		 4p0wA-3p41A:
27.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 11 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.53A 4p0wA-3q1oA:
31.4		 4p0wA-3q1oA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.43A 4p0wA-3qqvA:
33.9		 4p0wA-3qqvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 11 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.97A 4p0wA-3qqvA:
33.9		 4p0wA-3qqvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.83A 4p0wA-3qqvA:
33.9		 4p0wA-3qqvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 11 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.61A 4p0wA-3qqvA:
33.9		 4p0wA-3qqvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.39A 4q23A-3p41A:
23.6		 4q23A-3p41A:
28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.20A 4q23A-3q1oA:
31.0		 4q23A-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		9 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.49A 4q23A-3q1oA:
31.0		 4q23A-3q1oA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.47A 4q23A-3qqvA:
33.3		 4q23A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.43A 4q23A-3qqvA:
33.3		 4q23A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.92A 4q23A-3qqvA:
33.3		 4q23A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.56A 4q23A-3qqvA:
33.3		 4q23A-3qqvA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 LEU A  80
ARG A  94
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.96A 4rxdA-3p41A:
23.8		 4rxdA-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.49A 4rxdA-3p41A:
23.8		 4rxdA-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.22A 4rxdA-3q1oA:
29.4		 4rxdA-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.50A 4rxdA-3q1oA:
29.4		 4rxdA-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.29A 4rxdA-3qqvA:
33.4		 4rxdA-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.78A 4rxdA-3qqvA:
33.4		 4rxdA-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.59A 4rxdA-3qqvA:
33.4		 4rxdA-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		6 / 10 LEU A  80
ARG A  94
GLN A 157
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.93A 4rxdB-3p41A:
24.0		 4rxdB-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.48A 4rxdB-3p41A:
24.0		 4rxdB-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.22A 4rxdB-3q1oA:
29.9		 4rxdB-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.49A 4rxdB-3q1oA:
29.9		 4rxdB-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.42A 4rxdB-3qqvA:
33.7		 4rxdB-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.35A 4rxdB-3qqvA:
33.7		 4rxdB-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.79A 4rxdB-3qqvA:
33.7		 4rxdB-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.59A 4rxdB-3qqvA:
33.7		 4rxdB-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 LEU A  80
ARG A  94
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.95A 4rxdC-3p41A:
24.1		 4rxdC-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 10 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.48A 4rxdC-3p41A:
24.1		 4rxdC-3p41A:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.23A 4rxdC-3q1oA:
29.9		 4rxdC-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 10 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.49A 4rxdC-3q1oA:
29.9		 4rxdC-3q1oA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A 105
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.41A 4rxdC-3qqvA:
33.7		 4rxdC-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.79A 4rxdC-3qqvA:
33.7		 4rxdC-3qqvA:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.59A 4rxdC-3qqvA:
33.7		 4rxdC-3qqvA:
27.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		8 / 8 SER A  79
LEU A  80
ASP A  83
ASP A  89
ARG A  94
MET A 153
GLN A 157
LYS A 180
 DMA  A 300 (-3.7A)
None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 ( 4.3A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.63A 4umjA-3p41A:
43.4		 4umjA-3p41A:
76.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 8 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
 0.69A 4umjA-3q1oA:
29.3		 4umjA-3q1oA:
35.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 8 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
MET A 159
LYS A 186
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 (-3.1A)
 0.75A 4umjA-3q1oA:
29.3		 4umjA-3q1oA:
35.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 8 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.99A 4umjA-3qqvA:
27.6		 4umjA-3qqvA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 8 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
 0.51A 4umjA-3qqvA:
27.6		 4umjA-3qqvA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		9 / 9 SER A  79
LEU A  80
ASP A  83
ASP A  89
ARG A  94
MET A 153
GLN A 157
LYS A 180
THR A 181
 DMA  A 300 (-3.7A)
None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 ( 4.3A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.40A 4umjB-3p41A:
43.8		 4umjB-3p41A:
76.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
 0.51A 4umjB-3q1oA:
29.7		 4umjB-3q1oA:
35.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		8 / 9 SER A  88
LEU A  89
ASP A  92
ASP A  98
ARG A 103
MET A 159
LYS A 186
THR A 187
 DMA  A 501 (-3.4A)
DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
 0.71A 4umjB-3q1oA:
29.7		 4umjB-3q1oA:
35.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 383 ( 4.0A)
 0.84A 4umjB-3qqvA:
27.7		 4umjB-3qqvA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.50A 4umjB-3qqvA:
27.7		 4umjB-3qqvA:
30.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 6 HIS A  76
GLY A  43
GLU A  73
ARG A  45
 DMA  A 299 (-4.0A)
DMA  A 299 ( 3.7A)
DMA  A 299 ( 4.4A)
None
 1.11A 4zbqA-3p41A:
3.9		 4zbqA-3p41A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 6 HIS A  85
GLY A  46
GLU A  82
ARG A  48
 DMA  A 500 (-3.7A)
DMA  A 500 (-3.4A)
DMA  A 500 ( 4.6A)
None
 0.94A 4zbqA-3q1oA:
2.1		 4zbqA-3q1oA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 4gp1 POLYPRENYL
SYNTHETASE
(Pyrobaculum
calidifontis) 		4 / 6 HIS A  78
GLY A  45
GLU A  75
ARG A  47
 DMA  A 402 (-3.9A)
DMA  A 402 (-3.5A)
DMA  A 402 ( 4.9A)
None
 1.19A 4zbqA-4gp1A:
2.4		 4zbqA-4gp1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 12 LEU A  80
ARG A  94
LYS A 180
THR A 181
GLN A 219
 None
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
None
POP  A 301 ( 4.5A)
 0.98A 5cg5A-3p41A:
23.4		 5cg5A-3p41A:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 12 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.47A 5cg5A-3p41A:
23.4		 5cg5A-3p41A:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 12 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.19A 5cg5A-3q1oA:
30.8		 5cg5A-3q1oA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 12 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.48A 5cg5A-3q1oA:
30.8		 5cg5A-3q1oA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 105
ARG A 117
LYS A 215
THR A 216
GLN A 254
LYS A 271
 None
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 1.17A 5cg5A-3qqvA:
33.0		 5cg5A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
TYR A 219
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 4.9A)
 0.93A 5cg5A-3qqvA:
33.0		 5cg5A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.58A 5cg5A-3qqvA:
33.0		 5cg5A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		7 / 12 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
THR A 181
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
None
 0.45A 5cg6A-3p41A:
24.0		 5cg6A-3p41A:
27.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 12 ASP A  98
ARG A 103
GLN A 225
ASP A 228
LYS A 242
 MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 1.20A 5cg6A-3q1oA:
31.6		 5cg6A-3q1oA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		10 / 12 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
THR A 187
GLN A 225
ASP A 228
LYS A 242
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 500 (-3.4A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
DMA  A 501 (-2.7A)
 0.46A 5cg6A-3q1oA:
31.6		 5cg6A-3q1oA:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 105
ASP A 108
ARG A 117
GLN A 191
LYS A 215
LYS A 271
 None
MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 384 ( 2.8A)
 1.35A 5cg6A-3qqvA:
33.8		 5cg6A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
THR A 216
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
 0.81A 5cg6A-3qqvA:
33.8		 5cg6A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 12 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
THR A 216
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 ( 4.0A)
DMA  A 383 (-3.2A)
 0.57A 5cg6A-3qqvA:
33.8		 5cg6A-3qqvA:
29.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_B_ACRB1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 2ick ISOPENTENYL-DIPHOSPH
ATE DELTA ISOMERASE
(Homo
sapiens) 		5 / 10 ASN A 167
GLU A 168
LYS A  37
GLU A  20
ARG A 112
 None
DMA  A 301 ( 4.7A)
DMA  A 301 (-2.3A)
None
DMA  A 301 ( 4.6A)
 1.13A 5cltB-2ickA:
0.0		 5cltB-2ickA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		3 / 3 ASP A 222
LEU A  80
ARG A  94
 None
None
DMA  A 300 (-2.9A)
 0.57A 5e8qA-3p41A:
undetectable		 5e8qA-3p41A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 9 LEU A  80
ASP A  83
ASP A  89
ARG A  94
LYS A 180
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
 0.66A 5eroA-3p41A:
21.8		 5eroA-3p41A:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 9 LEU A  89
ASP A  92
ASP A  98
ARG A 103
LYS A 186
GLN A 225
ASP A 228
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
 0.69A 5eroA-3q1oA:
24.3		 5eroA-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		8 / 9 LEU A 105
ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
LYS A 271
LYS A 281
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
DMA  A 384 (-2.4A)
 0.88A 5eroA-3qqvA:
28.3		 5eroA-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 9 ASP A  92
ASP A  98
ARG A 103
LYS A 186
GLN A 225
ASP A 228
ASP A 229
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
None
 0.76A 5eroB-3q1oA:
24.5		 5eroB-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 9 ASP A  92
ASP A  98
LYS A 186
GLN A 225
ASP A 228
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
 1.50A 5eroB-3q1oA:
24.5		 5eroB-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 9 ARG A 117
LYS A 215
GLN A 254
ASP A 258
LYS A 271
LYS A 281
 DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
None
DMA  A 384 ( 2.8A)
DMA  A 384 (-2.4A)
 0.85A 5eroB-3qqvA:
28.0		 5eroB-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 9 ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
LYS A 271
LYS A 281
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
DMA  A 384 (-2.4A)
 0.90A 5eroB-3qqvA:
28.0		 5eroB-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 10 ASP A  83
ASP A  84
ASP A  89
ARG A  94
LYS A 180
 MG  A 297 (-2.5A)
None
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
POP  A 301 ( 2.4A)
 0.75A 5eroC-3p41A:
21.9		 5eroC-3p41A:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 10 ASP A  92
ASP A  93
ASP A  98
ARG A 103
GLN A 225
ASP A 228
ASP A 229
 MG  A 400 ( 2.8A)
None
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
None
 0.75A 5eroC-3q1oA:
24.6		 5eroC-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		7 / 10 ASP A  92
ASP A  93
ASP A  98
LYS A 186
GLN A 225
ASP A 228
ASP A 229
 MG  A 400 ( 2.8A)
None
MG  A 400 ( 3.2A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
None
 0.61A 5eroC-3q1oA:
24.6		 5eroC-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  92
ASP A  98
ARG A 103
ASP A 229
LYS A 242
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
None
DMA  A 501 (-2.7A)
 1.29A 5eroC-3q1oA:
24.6		 5eroC-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 10 ASP A  92
ASP A  98
LYS A 186
GLN A 225
ASP A 228
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
 1.47A 5eroC-3q1oA:
24.6		 5eroC-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		6 / 10 ASP A  98
ASP A  93
ARG A 103
GLN A 225
ASP A 228
ASP A 229
 MG  A 400 ( 3.2A)
None
DMA  A 501 (-3.0A)
DMA  A 501 ( 3.8A)
DMA  A 501 ( 3.5A)
None
 1.39A 5eroC-3q1oA:
24.6		 5eroC-3q1oA:
26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 ASP A 108
ASP A 109
ASP A 112
ARG A 117
LYS A 215
GLN A 254
LYS A 271
 MG  A 381 (-2.4A)
None
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 ( 2.8A)
 0.88A 5eroC-3qqvA:
27.7		 5eroC-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 108
ASP A 109
ASP A 112
LYS A 215
GLN A 254
LYS A 281
 MG  A 381 (-2.4A)
None
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 (-2.4A)
 0.79A 5eroC-3qqvA:
27.7		 5eroC-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		7 / 10 ASP A 109
ASP A 112
ARG A 117
LYS A 215
GLN A 254
ASP A 258
LYS A 271
 None
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
None
DMA  A 384 ( 2.8A)
 0.93A 5eroC-3qqvA:
27.7		 5eroC-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		6 / 10 ASP A 109
ASP A 112
LYS A 215
GLN A 254
ASP A 258
LYS A 281
 None
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
None
DMA  A 384 (-2.4A)
 0.97A 5eroC-3qqvA:
27.7		 5eroC-3qqvA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 PHE A  57
ILE A 106
GLN A 101
ARG A 117
 None
None
DMA  A 383 (-3.8A)
DMA  A 384 (-3.0A)
 1.33A 5jm4A-3qqvA:
5.4		 5jm4A-3qqvA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 2ick ISOPENTENYL-DIPHOSPH
ATE DELTA ISOMERASE
(Homo
sapiens) 		5 / 12 GLU A  96
ARG A  71
GLN A  69
ARG A 111
LEU A 113
 None
DMA  A 301 (-2.6A)
None
None
None
 1.45A 5m54B-2ickA:
undetectable		 5m54B-2ickA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 7 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.93A 6g31A-3p41A:
21.7		 6g31A-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		6 / 7 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
 1.00A 6g31A-3q1oA:
23.2		 6g31A-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 108
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 1.02A 6g31A-3qqvA:
27.4		 6g31A-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 7 ASP A 108
ARG A 117
GLN A 191
LYS A 281
 MG  A 381 (-2.4A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-2.4A)
 1.20A 6g31A-3qqvA:
27.4		 6g31A-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 108
ASP A 112
ARG A 117
GLN A 254
LYS A 281
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
DMA  A 384 (-2.4A)
 1.07A 6g31A-3qqvA:
27.4		 6g31A-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.96A 6g31A-3qqvA:
27.4		 6g31A-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 6 ASP A  83
ASP A  89
ARG A  94
GLN A 157
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.82A 6g31B-3p41A:
21.7		 6g31B-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 6 ASP A  92
ASP A  98
ARG A 103
GLN A 163
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.81A 6g31B-3q1oA:
23.3		 6g31B-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 108
ASP A 112
ARG A 117
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.85A 6g31B-3qqvA:
10.6		 6g31B-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 5 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 1.11A 6g31C-3p41A:
21.6		 6g31C-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 5 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
 1.12A 6g31C-3q1oA:
23.4		 6g31C-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 108
ASP A 112
ARG A 117
GLN A 191
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 1.23A 6g31C-3qqvA:
27.9		 6g31C-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 108
ASP A 112
ARG A 117
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
 0.99A 6g31C-3qqvA:
27.9		 6g31C-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 7 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.67A 6g31D-3p41A:
21.1		 6g31D-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		6 / 7 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
GLN A 225
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.63A 6g31D-3q1oA:
22.4		 6g31D-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.97A 6g31D-3qqvA:
26.9		 6g31D-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.67A 6g31D-3qqvA:
26.9		 6g31D-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 4 LEU A  80
ASP A  83
ASP A  89
ARG A  94
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
 0.32A 6g31E-3p41A:
9.6		 6g31E-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 4 LEU A  89
ASP A  92
ASP A  98
ARG A 103
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
 0.47A 6g31E-3q1oA:
17.4		 6g31E-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 4 LEU A 105
ASP A 108
ASP A 112
ARG A 117
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
 0.46A 6g31E-3qqvA:
21.1		 6g31E-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 5 ASP A  83
ASP A  89
ARG A  94
GLN A 157
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.61A 6g31F-3p41A:
21.8		 6g31F-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 5 ASP A  92
ASP A  98
ARG A 103
GLN A 163
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.69A 6g31F-3q1oA:
23.4		 6g31F-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 108
ASP A 112
ARG A 117
GLN A 191
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.96A 6g31F-3qqvA:
27.8		 6g31F-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 5 ASP A 108
ASP A 112
ARG A 117
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.88A 6g31F-3qqvA:
27.8		 6g31F-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 7 ASP A  83
ASP A  89
ARG A  94
GLN A 157
LYS A 180
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
POP  A 301 ( 2.4A)
 0.66A 6g31G-3p41A:
20.8		 6g31G-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		6 / 7 ASP A  92
ASP A  98
ARG A 103
GLN A 163
LYS A 186
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
 0.69A 6g31G-3q1oA:
22.0		 6g31G-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 108
ASP A 112
ARG A 117
GLN A 191
LYS A 215
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
DMA  A 384 (-3.0A)
 0.98A 6g31G-3qqvA:
26.4		 6g31G-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 7 ASP A 108
ASP A 112
ARG A 117
LYS A 215
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 0.70A 6g31G-3qqvA:
26.4		 6g31G-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 5 ASP A  92
ASP A  98
GLN A 163
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.62A 6g31H-3q1oA:
22.1		 6g31H-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_I_ZOLI401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 4 ASP A  92
ASP A  98
LYS A 186
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.1A)
DMA  A 501 ( 3.8A)
 0.83A 6g31I-3q1oA:
22.9		 6g31I-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		5 / 6 LEU A  80
ASP A  83
ASP A  89
ARG A  94
GLN A 157
 None
MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.94A 6g31J-3p41A:
21.8		 6g31J-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 6 LEU A  89
ASP A  92
ASP A  98
ARG A 103
GLN A 163
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
 0.96A 6g31J-3q1oA:
23.4		 6g31J-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 6 LEU A  89
ASP A  92
ASP A  98
GLN A 163
GLN A 225
 DMA  A 501 ( 4.8A)
MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.65A 6g31J-3q1oA:
23.4		 6g31J-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 6 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 191
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 1.24A 6g31J-3qqvA:
13.3		 6g31J-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		5 / 6 LEU A 105
ASP A 108
ASP A 112
ARG A 117
GLN A 254
 None
MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 1.01A 6g31J-3qqvA:
13.3		 6g31J-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 4 ASP A  83
ASP A  89
ARG A  94
GLN A 157
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.61A 6g31K-3p41A:
20.5		 6g31K-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 4 ASP A  92
ASP A  98
ARG A 103
GLN A 163
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
 0.62A 6g31K-3q1oA:
21.6		 6g31K-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p41 GERANYLTRANSTRANSFER
ASE
(Pseudomonas
protegens) 		4 / 6 ASP A  83
ASP A  89
ARG A  94
GLN A 157
 MG  A 297 (-2.5A)
MG  A 297 (-2.5A)
DMA  A 300 (-2.9A)
DMA  A 300 (-3.6A)
 0.70A 6g31L-3p41A:
21.7		 6g31L-3p41A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		5 / 6 ASP A  92
ASP A  98
ARG A 103
GLN A 163
GLN A 225
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.0A)
DMA  A 501 (-3.6A)
DMA  A 501 ( 3.8A)
 0.87A 6g31L-3q1oA:
23.1		 6g31L-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q1o GERANYLTRANSTRANSFER
ASE (ISPA)
(Helicobacter
pylori) 		4 / 6 ASP A  92
ASP A  98
GLN A 163
LYS A 250
 MG  A 400 ( 2.8A)
MG  A 400 ( 3.2A)
DMA  A 501 (-3.6A)
None
 1.50A 6g31L-3q1oA:
23.1		 6g31L-3q1oA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 108
ASP A 112
ARG A 117
GLN A 191
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 384 (-3.9A)
 0.97A 6g31L-3qqvA:
12.3		 6g31L-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3qqv GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
(Corynebacterium
glutamicum) 		4 / 6 ASP A 108
ASP A 112
ARG A 117
GLN A 254
 MG  A 381 (-2.4A)
MG  A 381 (-2.8A)
DMA  A 384 (-3.0A)
DMA  A 383 (-3.2A)
 1.02A 6g31L-3qqvA:
12.3		 6g31L-3qqvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 2ick ISOPENTENYL-DIPHOSPH
ATE DELTA ISOMERASE
(Homo
sapiens) 		4 / 8 HIS A  41
LEU A  51
GLY A  49
GLU A 149
 MN  A 229 (-3.4A)
None
None
DMA  A 301 ( 2.5A)
 0.85A 6mdqA-2ickA:
undetectable		 6mdqA-2ickA:
16.74