SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DLZ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_L_FUAL710_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	5 / 11	SER A 48 PHE A 2 VAL A 36 PHE A 28 VAL A 44	DLZ A 191 (-3.5A) None None None None	1.43A	1q23L-3a3gA: undetectable	1q23L-3a3gA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	5 / 12	TYR A 159 GLY A 46 GLY A 100 LEU A 49 VAL A 143	None None None DLZ A 191 (-4.2A) None	0.99A	2zulA-3a3gA: undetectable	2zulA-3a3gA: 16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	12 / 12	VAL A 41 CYH A 47 SER A 48 LEU A 49 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ASN A 101 ILE A 102	DLZ A 191 (-4.4A) DLZ A 191 (-3.6A) DLZ A 191 (-3.5A) DLZ A 191 (-4.2A) DLZ A 191 (-4.1A) DLZ A 191 (-3.9A) DLZ A 191 (-3.5A) DLZ A 191 (-3.4A) DLZ A 191 (-3.4A) DLZ A 191 ( 4.6A) DLZ A 191 (-4.5A) DLZ A 191 (-4.1A)	0.38A	3a35A-3a3gA: 35.3	3a35A-3a3gA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	12 / 12	VAL A 41 CYH A 47 SER A 48 LEU A 49 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ASN A 101 ILE A 102	DLZ A 191 (-4.4A) DLZ A 191 (-3.6A) DLZ A 191 (-3.5A) DLZ A 191 (-4.2A) DLZ A 191 (-4.1A) DLZ A 191 (-3.9A) DLZ A 191 (-3.5A) DLZ A 191 (-3.4A) DLZ A 191 (-3.4A) DLZ A 191 ( 4.6A) DLZ A 191 (-4.5A) DLZ A 191 (-4.1A)	0.44A	3a35B-3a3gA: 32.0	3a35B-3a3gA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	12 / 12	VAL A 41 CYH A 47 SER A 48 LEU A 49 THR A 50 ASP A 64 GLN A 65 ALA A 66 THR A 69 THR A 70 ASN A 101 ILE A 102	DLZ A 191 (-4.4A) DLZ A 191 (-3.6A) DLZ A 191 (-3.5A) DLZ A 191 (-4.2A) DLZ A 191 (-4.1A) DLZ A 191 (-3.9A) DLZ A 191 (-3.5A) DLZ A 191 (-3.4A) DLZ A 191 (-3.4A) DLZ A 191 ( 4.6A) DLZ A 191 (-4.5A) DLZ A 191 (-4.1A)	0.38A	3a3bA-3a3gA: 33.7	3a3bA-3a3gA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A9E_B_REAB1_1 (RETINOIC ACID RECEPTOR ALPHA)	6dd6	PHOTOLYASE PHRB (Agrobacterium tumefaciens)	5 / 11	LEU A 8 ARG A 108 PHE A 116 VAL A 5 LEU A 4	DLZ A 602 (-3.7A) DLZ A 602 ( 4.8A) None None None	1.35A	3a9eB-6dd6A: undetectable	3a9eB-6dd6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARU_A_PNXA607_1 (CHITINASE A)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	4 / 8	VAL A 41 GLY A 100 GLU A 181 GLY A 142	DLZ A 191 (-4.4A) None None None	0.75A	3aruA-3a3gA: undetectable	3aruA-3a3gA: 15.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DDY_A_RBFA187_1 (LUMAZINE PROTEIN)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	7 / 12	CYH A 47 ILE A 63 ASP A 64 GLN A 65 ALA A 66 ASN A 101 ILE A 102	DLZ A 191 (-3.6A) DLZ A 191 (-4.7A) DLZ A 191 (-3.9A) DLZ A 191 (-3.5A) DLZ A 191 (-3.4A) DLZ A 191 (-4.5A) DLZ A 191 (-4.1A)	0.92A	3ddyA-3a3gA: 29.2	3ddyA-3a3gA: 55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3DDY_A_RBFA187_1 (LUMAZINE PROTEIN)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	10 / 12	VAL A 41 CYH A 47 SER A 48 THR A 50 ILE A 63 ASP A 64 GLN A 65 ALA A 66 THR A 69 ILE A 102	DLZ A 191 (-4.4A) DLZ A 191 (-3.6A) DLZ A 191 (-3.5A) DLZ A 191 (-4.1A) DLZ A 191 (-4.7A) DLZ A 191 (-3.9A) DLZ A 191 (-3.5A) DLZ A 191 (-3.4A) DLZ A 191 (-3.4A) DLZ A 191 (-4.1A)	0.55A	3ddyA-3a3gA: 29.2	3ddyA-3a3gA: 55.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U52_A_CUA515_0 (PHENOL HYDROXYLASE COMPONENT PHL PHENOL HYDROXYLASE COMPONENT PHN)	3zxs	CRYPTOCHROME B (Rhodobacter sphaeroides)	3 / 3	HIS A 43 HIS A 214 ILE A 48	DLZ A1511 ( 3.9A) None DLZ A1511 ( 4.6A)	0.82A	3u52A-3zxsA: undetectable 3u52C-3zxsA: undetectable	3u52A-3zxsA: 18.66 3u52C-3zxsA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_A_MIXA1301_1 (DNA TOPOISOMERASE 2-BETA)	3a3g	LUMAZINE PROTEIN (Photobacterium kishitanii)	4 / 7	GLY A 142 ILE A 102 GLU A 181 GLN A 7	None DLZ A 191 (-4.1A) None None	1.09A	4g0vA-3a3gA: undetectable	4g0vA-3a3gA: 13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	3zxs	CRYPTOCHROME B (Rhodobacter sphaeroides)	5 / 12	ALA A 18 GLN A 11 VAL A 34 LEU A 109 LEU A 113	None None DLZ A1511 (-4.5A) None None	1.05A	4qzuC-3zxsA: undetectable	4qzuC-3zxsA: 12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H8T_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	3zxs	CRYPTOCHROME B (Rhodobacter sphaeroides)	5 / 12	LEU A 113 ALA A 101 ILE A 51 ILE A 83 LEU A 395	None None DLZ A1511 (-4.0A) None DLZ A1511 ( 4.4A)	1.16A	5h8tA-3zxsA: undetectable	5h8tA-3zxsA: 13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUI_B_CTCB405_1 (TETRACYCLINE DESTRUCTASE TET(50))	3zxs	CRYPTOCHROME B (Rhodobacter sphaeroides)	4 / 5	ASP A 106 ARG A 108 LEU A 52 MET A 55	None None None DLZ A1511 ( 3.7A)	1.15A	5tuiB-3zxsA: undetectable	5tuiB-3zxsA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA409_0 (UNCHARACTERIZED PROTEIN KDOO)	3zxs	CRYPTOCHROME B (Rhodobacter sphaeroides)	3 / 3	ASP A 10 PHE A 128 ARG A 307	DLZ A1511 (-2.5A) None None	1.15A	5yw0A-3zxsA: undetectable	5yw0A-3zxsA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA409_0 (UNCHARACTERIZED PROTEIN KDOO)	6dd6	PHOTOLYASE PHRB (Agrobacterium tumefaciens)	3 / 3	ASP A 10 PHE A 132 ARG A 311	DLZ A 602 (-3.0A) None None	0.88A	5yw0A-6dd6A: undetectable	5yw0A-6dd6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_A_GMJA301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	6dd6	PHOTOLYASE PHRB (Agrobacterium tumefaciens)	5 / 12	LEU A 12 PHE A 83 VAL A 34 VAL A 109 TYR A 271	None DLZ A 602 (-4.2A) DLZ A 602 (-4.6A) None None	1.09A	6djzA-6dd6A: undetectable	6djzA-6dd6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_C_GMJC301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	6dd6	PHOTOLYASE PHRB (Agrobacterium tumefaciens)	5 / 12	LEU A 12 PHE A 83 VAL A 34 VAL A 109 TYR A 271	None DLZ A 602 (-4.2A) DLZ A 602 (-4.6A) None None	1.12A	6djzC-6dd6A: undetectable	6djzC-6dd6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ECT_A_SAMA1300_1 (STIE PROTEIN)	6dd6	PHOTOLYASE PHRB (Agrobacterium tumefaciens)	4 / 5	ARG A 108 THR A 102 GLN A 11 ASP A 125	DLZ A 602 ( 4.8A) None None None	1.48A	6ectA-6dd6A: undetectable	6ectA-6dd6A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q23_L_FUAL710_2","CHLORAMPHENICOL ACETYLTRANSFERASE","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",5,"SER A  48;PHE A   2;VAL A  36;PHE A  28;VAL A  44","DLZ A 191 (-3.5A);None;None;None;None","1.43A","1q23L-3a3gA:undetectable",null],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",5,"TYR A 159;GLY A  46;GLY A 100;LEU A  49;VAL A 143","None;None;None;DLZ A 191 (-4.2A);None","0.99A","2zulA-3a3gA:undetectable","1q23L-3a3gA:22.46"],["3A35_A_RBFA191_1","LUMAZINE PROTEIN","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",12,"VAL A  41;CYH A  47;SER A  48;LEU A  49;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ASN A 101;ILE A 102","DLZ A 191 (-4.4A);DLZ A 191 (-3.6A);DLZ A 191 (-3.5A);DLZ A 191 (-4.2A);DLZ A 191 (-4.1A);DLZ A 191 (-3.9A);DLZ A 191 (-3.5A);DLZ A 191 (-3.4A);DLZ A 191 (-3.4A);DLZ A 191 ( 4.6A);DLZ A 191 (-4.5A);DLZ A 191 (-4.1A)","0.38A","3a35A-3a3gA:35.3","2zulA-3a3gA:16.80"],["3A35_B_RBFB191_1","LUMAZINE PROTEIN","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",12,"VAL A  41;CYH A  47;SER A  48;LEU A  49;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ASN A 101;ILE A 102","DLZ A 191 (-4.4A);DLZ A 191 (-3.6A);DLZ A 191 (-3.5A);DLZ A 191 (-4.2A);DLZ A 191 (-4.1A);DLZ A 191 (-3.9A);DLZ A 191 (-3.5A);DLZ A 191 (-3.4A);DLZ A 191 (-3.4A);DLZ A 191 ( 4.6A);DLZ A 191 (-4.5A);DLZ A 191 (-4.1A)","0.44A","3a35B-3a3gA:32.0","3a35A-3a3gA:100.00"],["3A3B_A_RBFA191_1","LUMAZINE PROTEIN","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",12,"VAL A  41;CYH A  47;SER A  48;LEU A  49;THR A  50;ASP A  64;GLN A  65;ALA A  66;THR A  69;THR A  70;ASN A 101;ILE A 102","DLZ A 191 (-4.4A);DLZ A 191 (-3.6A);DLZ A 191 (-3.5A);DLZ A 191 (-4.2A);DLZ A 191 (-4.1A);DLZ A 191 (-3.9A);DLZ A 191 (-3.5A);DLZ A 191 (-3.4A);DLZ A 191 (-3.4A);DLZ A 191 ( 4.6A);DLZ A 191 (-4.5A);DLZ A 191 (-4.1A)","0.38A","3a3bA-3a3gA:33.7","3a35B-3a3gA:100.00"],["3A9E_B_REAB1_1","RETINOIC ACID RECEPTOR ALPHA","6dd6","PHOTOLYASE PHRB","Agrobacterium tumefaciens",5,"LEU A   8;ARG A 108;PHE A 116;VAL A   5;LEU A   4","DLZ A 602 (-3.7A);DLZ A 602 ( 4.8A);None;None;None","1.35A","3a9eB-6dd6A:undetectable","3a3bA-3a3gA:100.00"],["3ARU_A_PNXA607_1","CHITINASE A","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",4,"VAL A  41;GLY A 100;GLU A 181;GLY A 142","DLZ A 191 (-4.4A);None;None;None","0.75A","3aruA-3a3gA:undetectable","3a9eB-6dd6A:undetectable"],["3DDY_A_RBFA187_1","LUMAZINE PROTEIN","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",7,"CYH A  47;ILE A  63;ASP A  64;GLN A  65;ALA A  66;ASN A 101;ILE A 102","DLZ A 191 (-3.6A);DLZ A 191 (-4.7A);DLZ A 191 (-3.9A);DLZ A 191 (-3.5A);DLZ A 191 (-3.4A);DLZ A 191 (-4.5A);DLZ A 191 (-4.1A)","0.92A","3ddyA-3a3gA:29.2","3aruA-3a3gA:15.05"],["3DDY_A_RBFA187_1","LUMAZINE PROTEIN","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",10,"VAL A  41;CYH A  47;SER A  48;THR A  50;ILE A  63;ASP A  64;GLN A  65;ALA A  66;THR A  69;ILE A 102","DLZ A 191 (-4.4A);DLZ A 191 (-3.6A);DLZ A 191 (-3.5A);DLZ A 191 (-4.1A);DLZ A 191 (-4.7A);DLZ A 191 (-3.9A);DLZ A 191 (-3.5A);DLZ A 191 (-3.4A);DLZ A 191 (-3.4A);DLZ A 191 (-4.1A)","0.55A","3ddyA-3a3gA:29.2","3ddyA-3a3gA:55.56"],["3U52_A_CUA515_0","PHENOL HYDROXYLASE COMPONENT PHL;PHENOL HYDROXYLASE COMPONENT PHN","3zxs","CRYPTOCHROME B","Rhodobacter sphaeroides",3,"HIS A  43;HIS A 214;ILE A  48","DLZ A1511 ( 3.9A);None;DLZ A1511 ( 4.6A)","0.82A","3u52A-3zxsA:undetectable;3u52C-3zxsA:undetectable","3ddyA-3a3gA:55.56"],["4G0V_A_MIXA1301_1","DNA TOPOISOMERASE 2-BETA","3a3g","LUMAZINE PROTEIN","Photobacterium kishitanii",4,"GLY A 142;ILE A 102;GLU A 181;GLN A   7","None;DLZ A 191 (-4.1A);None;None","1.09A","4g0vA-3a3gA:undetectable","3u52A-3zxsA:18.66;3u52C-3zxsA:19.74"],["4QZU_C_RTLC201_0","RETINOL-BINDING PROTEIN 2","3zxs","CRYPTOCHROME B","Rhodobacter sphaeroides",5,"ALA A  18;GLN A  11;VAL A  34;LEU A 109;LEU A 113","None;None;DLZ A1511 (-4.5A);None;None","1.05A","4qzuC-3zxsA:undetectable","4g0vA-3a3gA:13.15"],["5H8T_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","3zxs","CRYPTOCHROME B","Rhodobacter sphaeroides",5,"LEU A 113;ALA A 101;ILE A  51;ILE A  83;LEU A 395","None;None;DLZ A1511 (-4.0A);None;DLZ A1511 ( 4.4A)","1.16A","5h8tA-3zxsA:undetectable","4qzuC-3zxsA:12.15"],["5TUI_B_CTCB405_1","TETRACYCLINE DESTRUCTASE TET(50)","3zxs","CRYPTOCHROME B","Rhodobacter sphaeroides",4,"ASP A 106;ARG A 108;LEU A  52;MET A  55","None;None;None;DLZ A1511 ( 3.7A)","1.15A","5tuiB-3zxsA:undetectable","5h8tA-3zxsA:13.59"],["5YW0_A_ACTA409_0","UNCHARACTERIZED PROTEIN KDOO","3zxs","CRYPTOCHROME B","Rhodobacter sphaeroides",3,"ASP A  10;PHE A 128;ARG A 307","DLZ A1511 (-2.5A);None;None","1.15A","5yw0A-3zxsA:undetectable","5tuiB-3zxsA:21.30"],["5YW0_A_ACTA409_0","UNCHARACTERIZED PROTEIN KDOO","6dd6","PHOTOLYASE PHRB","Agrobacterium tumefaciens",3,"ASP A  10;PHE A 132;ARG A 311","DLZ A 602 (-3.0A);None;None","0.88A","5yw0A-6dd6A:undetectable","5yw0A-3zxsA:19.54"],["6DJZ_A_GMJA301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","6dd6","PHOTOLYASE PHRB","Agrobacterium tumefaciens",5,"LEU A  12;PHE A  83;VAL A  34;VAL A 109;TYR A 271","None;DLZ A 602 (-4.2A);DLZ A 602 (-4.6A);None;None","1.09A","6djzA-6dd6A:undetectable","5yw0A-6dd6A:undetectable"],["6DJZ_C_GMJC301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","6dd6","PHOTOLYASE PHRB","Agrobacterium tumefaciens",5,"LEU A  12;PHE A  83;VAL A  34;VAL A 109;TYR A 271","None;DLZ A 602 (-4.2A);DLZ A 602 (-4.6A);None;None","1.12A","6djzC-6dd6A:undetectable","6djzA-6dd6A:undetectable"],["6ECT_A_SAMA1300_1","STIE PROTEIN","6dd6","PHOTOLYASE PHRB","Agrobacterium tumefaciens",4,"ARG A 108;THR A 102;GLN A  11;ASP A 125","DLZ A 602 ( 4.8A);None;None;None","1.48A","6ectA-6dd6A:undetectable","6djzC-6dd6A:undetectable"]]