SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DLD'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)
3nbe RICIN B-LIKE LECTIN
(Clitocybe
nebularis)
4 / 6 LEU A 117
THR A 116
LEU A  84
ASP A  20
None
None
None
DLD  A 580 (-2.8A)
0.90A 2wm3A-3nbeA:
undetectable
2wm3A-3nbeA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)
3nbe RICIN B-LIKE LECTIN
(Clitocybe
nebularis)
5 / 12 LEU A 139
ILE A 126
GLY A  34
ASP A  20
ALA A  13
None
None
None
DLD  A 580 (-2.8A)
None
0.86A 5h5fA-3nbeA:
undetectable
5h5fA-3nbeA:
21.12