SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DKI'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1MUO_A_ADNA1_1 (AURORA-RELATED KINASE 1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 9	LEU A 52 GLY A 53 VAL A 60 ALA A 73 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.9A)	0.50A	1muoA-2w4oA: 24.4	1muoA-2w4oA: 31.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XKK_A_FMMA91_2 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 9	LEU A 52 VAL A 60 LEU A 104 LEU A 116 LEU A 120	DKI A1338 (-3.8A) DKI A1338 (-4.2A) None None DKI A1338 (-4.2A)	0.44A	1xkkA-2w4oA: 22.1	1xkkA-2w4oA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XKK_A_FMMA91_2 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 9	VAL A 60 LYS A 75 LEU A 104 LEU A 116 LEU A 120	DKI A1338 (-4.2A) None None None DKI A1338 (-4.2A)	0.63A	1xkkA-2w4oA: 22.1	1xkkA-2w4oA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YI4_A_ADNA306_1 (PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 10	LEU A 52 ALA A 73 ILE A 102 LEU A 118 LEU A 171	DKI A1338 (-3.8A) DKI A1338 ( 3.7A) DKI A1338 ( 4.4A) DKI A1338 ( 4.7A) DKI A1338 (-4.9A)	0.44A	1yi4A-2w4oA: 22.7	1yi4A-2w4oA: 28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_A_MIXA539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 12	LEU A 52 GLY A 53 VAL A 60 ALA A 73 VAL A 121 ASP A 164 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-3.9A) None DKI A1338 (-3.8A)	0.86A	2fumA-2w4oA: 18.7	2fumA-2w4oA: 29.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_A_MIXA539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 12	LEU A 52 GLY A 53 VAL A 60 VAL A 121 ASP A 164 ASN A 169 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 (-3.9A) None None DKI A1338 (-3.8A)	1.04A	2fumA-2w4oA: 18.7	2fumA-2w4oA: 29.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_C_MIXC2539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 12	LEU A 52 GLY A 53 VAL A 60 ALA A 73 VAL A 121 ASN A 169 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-3.9A) None DKI A1338 (-3.8A)	0.86A	2fumC-2w4oA: 23.8	2fumC-2w4oA: 29.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_D_NILD600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	4 / 6	LEU A 52 VAL A 60 LYS A 75 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-4.2A) None DKI A1338 (-4.9A)	0.65A	3cs9D-2w4oA: 19.6	3cs9D-2w4oA: 26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FUP_B_MI1B1_1 (TYROSINE-PROTEIN KINASE JAK2)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 12	LEU A 52 GLY A 53 GLY A 55 VAL A 60 ALA A 73 LYS A 75 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-3.3A) None DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None DKI A1338 (-4.9A)	0.53A	3fupB-2w4oA: 21.3	3fupB-2w4oA: 24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXN_A_MI1A1_1 (NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	8 / 12	LEU A 52 GLY A 53 VAL A 60 ALA A 73 LYS A 75 ILE A 102 LEU A 171 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None DKI A1338 ( 4.4A) DKI A1338 (-4.9A) DKI A1338 (-3.8A)	0.67A	3lxnA-2w4oA: 21.3	3lxnA-2w4oA: 28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXN_A_MI1A1_1 (NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	8 / 12	LEU A 52 GLY A 53 VAL A 60 ALA A 73 LYS A 75 VAL A 121 LEU A 171 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None DKI A1338 (-3.9A) DKI A1338 (-4.9A) DKI A1338 (-3.8A)	0.78A	3lxnA-2w4oA: 21.3	3lxnA-2w4oA: 28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UG2_A_IREA1_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 12	LEU A 52 VAL A 60 ALA A 73 LYS A 75 LEU A 116 LEU A 120 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None None DKI A1338 (-4.2A) DKI A1338 (-4.9A)	0.88A	3ug2A-2w4oA: 19.7	3ug2A-2w4oA: 24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CKJ_A_ADNA2014_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 10	LEU A 52 GLY A 53 GLY A 55 VAL A 60 ALA A 73 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-3.3A) None DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.9A)	0.61A	4ckjA-2w4oA: 21.3	4ckjA-2w4oA: 25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAA_A_RTZA401_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 11	VAL A 60 ALA A 73 LYS A 75 LEU A 118 LEU A 171	DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None DKI A1338 ( 4.7A) DKI A1338 (-4.9A)	0.47A	4iaaA-2w4oA: 22.5	4iaaA-2w4oA: 29.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IFG_A_1E8A601_1 (CALMODULIN-DOMAIN PROTEIN KINASE 1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	8 / 12	GLY A 53 VAL A 60 ALA A 73 LEU A 104 LEU A 116 GLY A 124 GLU A 125 LEU A 171	DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None None None None DKI A1338 (-4.9A)	0.79A	4ifgA-2w4oA: 34.1	4ifgA-2w4oA: 31.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_B_8PRB601_1 (RHODOPSIN KINASE)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	4 / 8	GLY A 55 VAL A 60 ALA A 73 LYS A 75	None DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None	0.25A	4l9iB-2w4oA: 20.5	4l9iB-2w4oA: 25.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O0W_A_ADNA501_1 (AURORA KINASE A)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 6	LEU A 52 GLY A 53 VAL A 60 ALA A 73 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.9A)	0.44A	4o0wA-2w4oA: 25.6	4o0wA-2w4oA: 31.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	9 / 12	LEU A 52 GLY A 53 GLY A 55 VAL A 60 ALA A 73 LYS A 75 LEU A 171 ALA A 184 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-3.3A) None DKI A1338 (-4.2A) DKI A1338 ( 3.7A) None DKI A1338 (-4.9A) DKI A1338 (-3.1A) DKI A1338 (-3.8A)	0.78A	4otiA-2w4oA: 17.4	4otiA-2w4oA: 29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 8	LEU A 52 VAL A 60 ILE A 102 HIS A 162 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-4.2A) DKI A1338 ( 4.4A) None DKI A1338 (-4.9A)	0.86A	4qrcA-2w4oA: 21.3	4qrcA-2w4oA: 28.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 8	LEU A 52 VAL A 60 LYS A 75 ILE A 102 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-4.2A) None DKI A1338 ( 4.4A) DKI A1338 (-4.9A)	0.76A	4qrcA-2w4oA: 21.3	4qrcA-2w4oA: 28.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZ7_A_1E8A901_1 (CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 10	ALA A 73 LYS A 75 ILE A 102 LEU A 120 VAL A 121 LEU A 171	DKI A1338 ( 3.7A) None DKI A1338 ( 4.4A) DKI A1338 (-4.2A) DKI A1338 (-3.9A) DKI A1338 (-4.9A)	0.63A	4rz7A-2w4oA: 9.4	4rz7A-2w4oA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V01_B_0LIB1770_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 9	LEU A 52 VAL A 60 LYS A 75 ILE A 102 LEU A 171 ILE A 183	DKI A1338 (-3.8A) DKI A1338 (-4.2A) None DKI A1338 ( 4.4A) DKI A1338 (-4.9A) None	0.90A	4v01B-2w4oA: 21.3	4v01B-2w4oA: 24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H2U_B_1N1B501_1 (PROTEIN-TYROSINE KINASE 6)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 12	LEU A 52 VAL A 60 ALA A 73 LEU A 120 LEU A 171 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.2A) DKI A1338 (-4.9A) DKI A1338 (-3.8A)	0.82A	5h2uB-2w4oA: 22.5	5h2uB-2w4oA: 24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_G_AZ1G2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	4 / 7	GLY A 53 GLY A 55 VAL A 60 LYS A 75	DKI A1338 (-3.3A) None DKI A1338 (-4.2A) None	0.31A	5izjA-2w4oA: 22.0	5izjA-2w4oA: 29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J5X_B_AZ1B2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAL-DAR-DAR- DAR-DAR)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	4 / 7	GLY A 53 GLY A 55 VAL A 60 LYS A 75	DKI A1338 (-3.3A) None DKI A1338 (-4.2A) None	0.35A	5j5xA-2w4oA: 22.5	5j5xA-2w4oA: 29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	6 / 12	GLY A 53 VAL A 60 ALA A 73 LEU A 171 ALA A 184 ASP A 185	DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 (-4.9A) DKI A1338 (-3.1A) DKI A1338 (-3.8A)	0.68A	5l2iA-2w4oA: 7.2	5l2iA-2w4oA: 27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LVN_A_ADNA402_1 (3-PHOSPHOINOSITIDE-D EPENDENT PROTEIN KINASE 1)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	7 / 11	LEU A 52 GLY A 53 VAL A 60 ALA A 73 LEU A 118 GLU A 125 LEU A 171	DKI A1338 (-3.8A) DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 ( 4.7A) None DKI A1338 (-4.9A)	0.51A	5lvnA-2w4oA: 13.2	5lvnA-2w4oA: 29.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 10	GLY A 53 VAL A 60 ALA A 73 ILE A 102 LEU A 120	DKI A1338 (-3.3A) DKI A1338 (-4.2A) DKI A1338 ( 3.7A) DKI A1338 ( 4.4A) DKI A1338 (-4.2A)	0.56A	5lw1E-2w4oA: 20.1	5lw1E-2w4oA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2w4o	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE IV (Homo sapiens)	5 / 9	LEU A 52 VAL A 60 LYS A 75 ILE A 102 ASP A 185	DKI A1338 (-3.8A) DKI A1338 (-4.2A) None DKI A1338 ( 4.4A) DKI A1338 (-3.8A)	1.02A	5yf9X-2w4oA: 21.5	5yf9X-2w4oA: 14.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MUO_A_ADNA1_1","AURORA-RELATED KINASE 1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-4.9A)","0.50A","1muoA-2w4oA:24.4",null],["1XKK_A_FMMA91_2","EPIDERMAL GROWTH FACTOR RECEPTOR","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;VAL A  60;LEU A 104;LEU A 116;LEU A 120","DKI A1338 (-3.8A);DKI A1338 (-4.2A);None;None;DKI A1338 (-4.2A)","0.44A","1xkkA-2w4oA:22.1","1muoA-2w4oA:31.73"],["1XKK_A_FMMA91_2","EPIDERMAL GROWTH FACTOR RECEPTOR","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"VAL A  60;LYS A  75;LEU A 104;LEU A 116;LEU A 120","DKI A1338 (-4.2A);None;None;None;DKI A1338 (-4.2A)","0.63A","1xkkA-2w4oA:22.1","1xkkA-2w4oA:27.39"],["1YI4_A_ADNA306_1","PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE PIM-1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;ALA A  73;ILE A 102;LEU A 118;LEU A 171","DKI A1338 (-3.8A);DKI A1338 ( 3.7A);DKI A1338 ( 4.4A);DKI A1338 ( 4.7A);DKI A1338 (-4.9A)","0.44A","1yi4A-2w4oA:22.7","1xkkA-2w4oA:27.39"],["2FUM_A_MIXA539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;VAL A 121;ASP A 164;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-3.9A);None;DKI A1338 (-3.8A)","0.86A","2fumA-2w4oA:18.7","1yi4A-2w4oA:28.53"],["2FUM_A_MIXA539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;GLY A  53;VAL A  60;VAL A 121;ASP A 164;ASN A 169;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 (-3.9A);None;None;DKI A1338 (-3.8A)","1.04A","2fumA-2w4oA:18.7","2fumA-2w4oA:29.46"],["2FUM_C_MIXC2539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;VAL A 121;ASN A 169;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-3.9A);None;DKI A1338 (-3.8A)","0.86A","2fumC-2w4oA:23.8","2fumA-2w4oA:29.46"],["3CS9_D_NILD600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",4,"LEU A  52;VAL A  60;LYS A  75;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-4.2A);None;DKI A1338 (-4.9A)","0.65A","3cs9D-2w4oA:19.6","2fumC-2w4oA:29.46"],["3FUP_B_MI1B1_1","TYROSINE-PROTEIN KINASE JAK2","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;GLY A  53;GLY A  55;VAL A  60;ALA A  73;LYS A  75;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-3.3A);None;DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;DKI A1338 (-4.9A)","0.53A","3fupB-2w4oA:21.3","3cs9D-2w4oA:26.25"],["3LXN_A_MI1A1_1","NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",8,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;LYS A  75;ILE A 102;LEU A 171;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;DKI A1338 ( 4.4A);DKI A1338 (-4.9A);DKI A1338 (-3.8A)","0.67A","3lxnA-2w4oA:21.3","3fupB-2w4oA:24.30"],["3LXN_A_MI1A1_1","NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",8,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;LYS A  75;VAL A 121;LEU A 171;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;DKI A1338 (-3.9A);DKI A1338 (-4.9A);DKI A1338 (-3.8A)","0.78A","3lxnA-2w4oA:21.3","3lxnA-2w4oA:28.37"],["3UG2_A_IREA1_1","EPIDERMAL GROWTH FACTOR RECEPTOR","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;VAL A  60;ALA A  73;LYS A  75;LEU A 116;LEU A 120;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;None;DKI A1338 (-4.2A);DKI A1338 (-4.9A)","0.88A","3ug2A-2w4oA:19.7","3lxnA-2w4oA:28.37"],["4CKJ_A_ADNA2014_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",6,"LEU A  52;GLY A  53;GLY A  55;VAL A  60;ALA A  73;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-3.3A);None;DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-4.9A)","0.61A","4ckjA-2w4oA:21.3","3ug2A-2w4oA:24.49"],["4IAA_A_RTZA401_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"VAL A  60;ALA A  73;LYS A  75;LEU A 118;LEU A 171","DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;DKI A1338 ( 4.7A);DKI A1338 (-4.9A)","0.47A","4iaaA-2w4oA:22.5","4ckjA-2w4oA:25.75"],["4IFG_A_1E8A601_1","CALMODULIN-DOMAIN PROTEIN KINASE 1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",8,"GLY A  53;VAL A  60;ALA A  73;LEU A 104;LEU A 116;GLY A 124;GLU A 125;LEU A 171","DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;None;None;None;DKI A1338 (-4.9A)","0.79A","4ifgA-2w4oA:34.1","4iaaA-2w4oA:29.08"],["4L9I_B_8PRB601_1","RHODOPSIN KINASE","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",4,"GLY A  55;VAL A  60;ALA A  73;LYS A  75","None;DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None","0.25A","4l9iB-2w4oA:20.5","4ifgA-2w4oA:31.99"],["4O0W_A_ADNA501_1","AURORA KINASE A","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-4.9A)","0.44A","4o0wA-2w4oA:25.6","4l9iB-2w4oA:25.20"],["4OTI_A_MI1A1001_1","SERINE\/THREONINE-PROTEIN KINASE N1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",9,"LEU A  52;GLY A  53;GLY A  55;VAL A  60;ALA A  73;LYS A  75;LEU A 171;ALA A 184;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-3.3A);None;DKI A1338 (-4.2A);DKI A1338 ( 3.7A);None;DKI A1338 (-4.9A);DKI A1338 (-3.1A);DKI A1338 (-3.8A)","0.78A","4otiA-2w4oA:17.4","4o0wA-2w4oA:31.95"],["4QRC_A_0LIA802_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;VAL A  60;ILE A 102;HIS A 162;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-4.2A);DKI A1338 ( 4.4A);None;DKI A1338 (-4.9A)","0.86A","4qrcA-2w4oA:21.3","4otiA-2w4oA:29.92"],["4QRC_A_0LIA802_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;VAL A  60;LYS A  75;ILE A 102;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-4.2A);None;DKI A1338 ( 4.4A);DKI A1338 (-4.9A)","0.76A","4qrcA-2w4oA:21.3","4qrcA-2w4oA:28.50"],["4RZ7_A_1E8A901_1","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",6,"ALA A  73;LYS A  75;ILE A 102;LEU A 120;VAL A 121;LEU A 171","DKI A1338 ( 3.7A);None;DKI A1338 ( 4.4A);DKI A1338 (-4.2A);DKI A1338 (-3.9A);DKI A1338 (-4.9A)","0.63A","4rz7A-2w4oA:9.4","4qrcA-2w4oA:28.50"],["4V01_B_0LIB1770_2","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",6,"LEU A  52;VAL A  60;LYS A  75;ILE A 102;LEU A 171;ILE A 183","DKI A1338 (-3.8A);DKI A1338 (-4.2A);None;DKI A1338 ( 4.4A);DKI A1338 (-4.9A);None","0.90A","4v01B-2w4oA:21.3","4rz7A-2w4oA:18.20"],["5H2U_B_1N1B501_1","PROTEIN-TYROSINE KINASE 6","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",6,"LEU A  52;VAL A  60;ALA A  73;LEU A 120;LEU A 171;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-4.2A);DKI A1338 (-4.9A);DKI A1338 (-3.8A)","0.82A","5h2uB-2w4oA:22.5","4v01B-2w4oA:24.35"],["5IZJ_G_AZ1G2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",4,"GLY A  53;GLY A  55;VAL A  60;LYS A  75","DKI A1338 (-3.3A);None;DKI A1338 (-4.2A);None","0.31A","5izjA-2w4oA:22.0","5h2uB-2w4oA:24.29"],["5J5X_B_AZ1B2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAL-DAR-DAR-DAR-DAR","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",4,"GLY A  53;GLY A  55;VAL A  60;LYS A  75","DKI A1338 (-3.3A);None;DKI A1338 (-4.2A);None","0.35A","5j5xA-2w4oA:22.5","5izjA-2w4oA:29.87"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",6,"GLY A  53;VAL A  60;ALA A  73;LEU A 171;ALA A 184;ASP A 185","DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 (-4.9A);DKI A1338 (-3.1A);DKI A1338 (-3.8A)","0.68A","5l2iA-2w4oA:7.2","5j5xA-2w4oA:29.87"],["5LVN_A_ADNA402_1","3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",7,"LEU A  52;GLY A  53;VAL A  60;ALA A  73;LEU A 118;GLU A 125;LEU A 171","DKI A1338 (-3.8A);DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 ( 4.7A);None;DKI A1338 (-4.9A)","0.51A","5lvnA-2w4oA:13.2","5l2iA-2w4oA:27.75"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"GLY A  53;VAL A  60;ALA A  73;ILE A 102;LEU A 120","DKI A1338 (-3.3A);DKI A1338 (-4.2A);DKI A1338 ( 3.7A);DKI A1338 ( 4.4A);DKI A1338 (-4.2A)","0.56A","5lw1E-2w4oA:20.1","5lvnA-2w4oA:29.60"],["5YF9_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","2w4o","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV","Homo sapiens",5,"LEU A  52;VAL A  60;LYS A  75;ILE A 102;ASP A 185","DKI A1338 (-3.8A);DKI A1338 (-4.2A);None;DKI A1338 ( 4.4A);DKI A1338 (-3.8A)","1.02A","5yf9X-2w4oA:21.5","5lw1E-2w4oA:15.84"]]