SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DJN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 TYR A 329
ASP A 322
TYR A 550
HIS A 492
 DJN  A 702 (-4.2A)
CA  A 703 (-2.1A)
None
DJN  A 702 (-3.5A)
 1.48A 2bytA-5wzrA:
undetectable		 2bytA-5wzrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 TYR A 329
ASP A 322
TYR A 550
HIS A 492
 DJN  A 702 (-4.2A)
CA  A 703 (-2.1A)
None
DJN  A 702 (-3.5A)
 1.48A 2bytD-5wzrA:
undetectable		 2bytD-5wzrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 12 ASP A 554
ASP A 561
GLY A 323
ILE A 274
VAL A 270
 None
DJN  A 702 (-2.9A)
None
None
None
 1.04A 3nu3A-5wzrA:
undetectable		 3nu3A-5wzrA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 9 ASP A 554
ASP A 561
GLY A 323
ILE A 274
VAL A 270
 None
DJN  A 702 (-2.9A)
None
None
None
 1.11A 3nuoA-5wzrA:
undetectable		 3nuoA-5wzrA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.17A 4feuB-5wzrA:
undetectable		 4feuB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.20A 4feuF-5wzrA:
undetectable		 4feuF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.19A 4fevB-5wzrA:
undetectable		 4fevB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.23A 4fevD-5wzrA:
undetectable		 4fevD-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fevF-5wzrA:
undetectable		 4fevF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.17A 4fewB-5wzrA:
undetectable		 4fewB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fewF-5wzrA:
undetectable		 4fewF-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4fexB-5wzrA:
undetectable		 4fexB-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.18A 4gkhD-5wzrA:
undetectable		 4gkhD-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 7 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.21A 4gkhG-5wzrA:
undetectable		 4gkhG-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 6 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.18A 4gkhJ-5wzrA:
undetectable		 4gkhJ-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 8 ASP A 561
ASP A 322
ASP A 371
ASP A 330
 DJN  A 702 (-2.9A)
CA  A 703 (-2.1A)
DJN  A 702 (-3.1A)
DJN  A 702 (-2.6A)
 1.19A 4gkiC-5wzrA:
undetectable		 4gkiC-5wzrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 5 TYR A 165
TYR A 191
GLU A 479
ASP A 561
 None
None
None
DJN  A 702 (-2.9A)
 1.48A 4x61A-5wzrA:
0.0		 4x61A-5wzrA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		5 / 10 ASP A 367
HIS A 320
HIS A 271
HIS A 492
ALA A 556
 None
CA  A 703 (-3.3A)
CA  A 703 (-3.2A)
DJN  A 702 (-3.5A)
DJN  A 702 ( 4.0A)
 1.30A 4yhaB-5wzrA:
undetectable		 4yhaB-5wzrA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Bifidobacterium
bifidum) 		4 / 4 ASP A 322
HIS A 271
HIS A 492
HIS A 366
 CA  A 703 (-2.1A)
CA  A 703 (-3.2A)
DJN  A 702 (-3.5A)
CA  A 703 ( 3.3A)
 1.31A 5ncdD-5wzrA:
3.9		 5ncdD-5wzrA:
16.77