SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DIH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.50A 1jdvA-3of3A:
32.7
1jdvD-3of3A:
32.7		 1jdvA-3of3A:
30.77
1jdvD-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.51A 1jdvB-3of3A:
32.5
1jdvC-3of3A:
33.0		 1jdvB-3of3A:
30.77
1jdvC-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.48A 1jdvA-3of3A:
32.7
1jdvD-3of3A:
32.7		 1jdvA-3of3A:
30.77
1jdvD-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 12 ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.54A 1jdvE-3of3A:
32.6
1jdvF-3of3A:
33.1		 1jdvE-3of3A:
30.77
1jdvF-3of3A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A 101
GLY A 191
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.26A 1odiA-3of3A:
25.9		 1odiA-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.43A 1odiA-3of3A:
25.9		 1odiA-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.45A 1odiB-3of3A:
35.3		 1odiB-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.41A 1odiC-3of3A:
35.6		 1odiC-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.46A 1odiD-3of3A:
35.4		 1odiD-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.42A 1odiE-3of3A:
35.4		 1odiE-3of3A:
34.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.43A 1odiF-3of3A:
35.4		 1odiF-3of3A:
34.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLU A 195
GLY A  77
HIS A  76
TYR A  86
VAL A  87
 DIH  A 500 (-2.9A)
None
None
None
None
 1.10A 1pg2A-3of3A:
undetectable		 1pg2A-3of3A:
20.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.53A 1pk7A-3of3A:
39.6		 1pk7A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 8 ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.56A 1pk7B-3of3A:
40.4		 1pk7B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 8 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.38A 1pk7B-3of3A:
40.4		 1pk7B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 1pk7C-3of3A:
22.1		 1pk7C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.27A 1pk7C-3of3A:
22.1		 1pk7C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.42A 1pk9A-3of3A:
39.9		 1pk9A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.37A 1pk9A-3of3A:
39.9		 1pk9A-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.12A 1pk9B-3of3A:
40.2		 1pk9B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.40A 1pk9B-3of3A:
40.2		 1pk9B-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		11 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.27A 1pk9C-3of3A:
43.8		 1pk9C-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.47A 1pw7A-3of3A:
39.9		 1pw7A-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.45A 1pw7B-3of3A:
40.8		 1pw7B-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.34A 1pw7B-3of3A:
40.8		 1pw7B-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.37A 1pw7C-3of3A:
41.2		 1pw7C-3of3A:
79.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		8 / 10 GLY A 203
PHE A 285
GLU A 286
GLY A 303
MET A 304
THR A 327
ASN A 328
HIS A 342
 DIH  A 401 (-3.4A)
DIH  A 401 (-4.6A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-4.2A)
DIH  A 401 (-3.1A)
DIH  A 401 (-3.6A)
 0.71A 1pwyE-2p4sA:
40.6		 1pwyE-2p4sA:
42.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		8 / 10 GLY A 203
PHE A 285
GLU A 286
GLY A 303
MET A 304
THR A 327
ASN A 328
HIS A 342
 DIH  A 401 (-3.4A)
DIH  A 401 (-4.6A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-4.2A)
DIH  A 401 (-3.1A)
DIH  A 401 (-3.6A)
 0.49A 1v3qE-2p4sA:
41.1		 1v3qE-2p4sA:
42.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
GLU A 195
ARG A  38
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
PO4  A 501 (-2.9A)
 1.41A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.26A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 ARG A 101
GLY A 191
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.26A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
GLU A 195
ARG A  38
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
PO4  A 501 (-2.9A)
 1.41A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.25A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.41A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.33A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.26A 1vhwA-3of3A:
42.5
1vhwD-3of3A:
42.5		 1vhwA-3of3A:
98.77
1vhwD-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.41A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.23A 1vhwC-3of3A:
42.6
1vhwE-3of3A:
42.3		 1vhwC-3of3A:
98.77
1vhwE-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 10 ARG A  38
GLY A 191
VAL A 192
GLU A 193
GLU A 195
 PO4  A 501 (-2.9A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
 1.40A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.34A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.25A 1vhwB-3of3A:
42.6
1vhwF-3of3A:
42.4		 1vhwB-3of3A:
98.77
1vhwF-3of3A:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 1z35A-3of3A:
37.8		 1z35A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.46A 1z35A-3of3A:
37.8		 1z35A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 9 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.42A 1z37A-3of3A:
38.1		 1z37A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 9 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.43A 1z37A-3of3A:
38.1		 1z37A-3of3A:
55.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.43A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.43A 2ac7A-3of3A:
36.0
2ac7B-3of3A:
36.1		 2ac7A-3of3A:
54.62
2ac7B-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		5 / 6 GLY A 203
GLU A 286
GLY A 303
MET A 304
ASN A 328
 DIH  A 401 (-3.4A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-3.1A)
 0.53A 3e9rA-2p4sA:
39.9		 3e9rA-2p4sA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		5 / 6 GLY A 203
GLU A 286
GLY A 303
MET A 304
ASN A 328
 DIH  A 401 (-3.4A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-3.1A)
 0.58A 3e9rC-2p4sA:
40.3		 3e9rC-2p4sA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		9 / 12 SER A 118
TYR A 173
ALA A 201
GLY A 203
GLU A 286
GLY A 303
MET A 304
ASN A 328
HIS A 342
 PO4  A 503 (-2.8A)
DIH  A 401 (-4.7A)
PO4  A 503 ( 3.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-3.1A)
DIH  A 401 (-3.6A)
 0.39A 3f8wA-2p4sA:
41.5		 3f8wA-2p4sA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		9 / 12 SER A 118
HIS A 171
TYR A 173
GLY A 203
GLU A 286
GLY A 303
MET A 304
ASN A 328
HIS A 342
 PO4  A 503 (-2.8A)
DIH  A 401 ( 4.0A)
DIH  A 401 (-4.7A)
DIH  A 401 (-3.4A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-3.1A)
DIH  A 401 (-3.6A)
 0.43A 3f8wB-2p4sA:
43.3		 3f8wB-2p4sA:
35.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		9 / 12 SER A 118
HIS A 171
TYR A 173
ALA A 201
GLY A 203
GLU A 286
GLY A 303
MET A 304
ASN A 328
 PO4  A 503 (-2.8A)
DIH  A 401 ( 4.0A)
DIH  A 401 (-4.7A)
PO4  A 503 ( 3.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-2.8A)
DIH  A 401 (-3.4A)
DIH  A 401 (-3.5A)
DIH  A 401 (-3.1A)
 0.36A 3f8wC-2p4sA:
41.3		 3f8wC-2p4sA:
35.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		3 / 3 MET A 194
MET A 180
PHE A 173
 DIH  A 500 (-3.8A)
None
DIH  A 500 (-4.3A)
 1.14A 3gn8A-3of3A:
undetectable		 3gn8A-3of3A:
17.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.58A 3u40A-3of3A:
36.3
3u40F-3of3A:
34.0		 3u40A-3of3A:
46.12
3u40F-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 0.50A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.44A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.47A 3u40B-3of3A:
35.7
3u40C-3of3A:
17.7		 3u40B-3of3A:
46.12
3u40C-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.41A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 12 GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.45A 3u40D-3of3A:
36.3
3u40E-3of3A:
35.7		 3u40D-3of3A:
46.12
3u40E-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
SER A 104
VAL A 192
GLU A 193
MET A 194
GLU A 195
ASP A 218
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.1A)
 0.70A 3u40A-3of3A:
36.3
3u40F-3of3A:
34.0		 3u40A-3of3A:
46.12
3u40F-3of3A:
46.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.43A 3uawA-3of3A:
38.2		 3uawA-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 11 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
None
 0.42A 3uawA-3of3A:
38.2		 3uawA-3of3A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.43A 3uayA-3of3A:
37.6		 3uayA-3of3A:
54.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		8 / 10 MET A  78
ARG A 101
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.34A 3uayA-3of3A:
37.6		 3uayA-3of3A:
54.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.35A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.33A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.48A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 SER A 104
GLY A 106
VAL A 192
GLU A 193
SER A 217
ASP A 218
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.73A 4d9hA-3of3A:
36.3		 4d9hA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 GLY A 106
VAL A 192
MET A 194
SER A 217
ASP A 218
 DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.95A 4da6A-3of3A:
36.0		 4da6A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 9 MET A  78
SER A 104
GLY A 106
VAL A 192
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.68A 4da6A-3of3A:
36.0		 4da6A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 ARG A 101
GLY A 191
ALA A 170
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.27A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 10 ARG A 101
GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.26A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 10 MET A  78
ARG A 101
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.45A 4da7A-3of3A:
36.5		 4da7A-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 106
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.45A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.29A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.31A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 11 MET A  78
ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
 0.54A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		7 / 11 SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
SER A 217
ASP A 218
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.73A 4danA-3of3A:
35.6		 4danA-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 12 ARG A 101
GLY A 191
VAL A 192
GLU A 193
GLU A 195
VAL A 108
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-2.9A)
None
 1.29A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 12 ARG A 101
GLY A 191
VAL A 192
GLU A 193
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.28A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 12 ARG A 101
SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ASP A 218
 PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
DIH  A 500 (-3.1A)
 0.67A 4danA-3of3A:
35.6
4danB-3of3A:
36.0		 4danA-3of3A:
50.97
4danB-3of3A:
50.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		5 / 12 ALA A 198
ARG A 169
GLY A 117
ALA A 301
GLY A 303
 None
PO4  A 503 (-3.9A)
PO4  A 503 (-3.4A)
None
DIH  A 401 (-3.4A)
 1.27A 4r29C-2p4sA:
undetectable		 4r29C-2p4sA:
20.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 9 ARG A 101
GLY A 191
ALA A 170
VAL A 192
MET A 194
GLU A 195
 PO4  A 501 (-2.8A)
None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.29A 5i3cA-3of3A:
41.3		 5i3cA-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 9 MET A  78
ARG A 101
SER A 104
GLY A 106
ALA A 170
VAL A 192
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 (-2.8A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.32A 5i3cA-3of3A:
41.3		 5i3cA-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 10 GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.39A 5i3cB-3of3A:
41.7		 5i3cB-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		9 / 10 MET A  78
SER A 104
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
None
 0.27A 5i3cB-3of3A:
41.7		 5i3cB-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 11 GLY A 106
ALA A 170
VAL A 192
ASP A 218
ILE A 220
 DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
DIH  A 500 (-3.1A)
None
 0.94A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		6 / 11 GLY A 191
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
 None
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
 1.37A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		10 / 11 MET A  78
SER A 104
GLY A 106
ALA A 170
VAL A 192
GLU A 193
MET A 194
GLU A 195
SER A 217
ILE A 220
 DIH  A 500 (-3.6A)
PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 ( 4.8A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
DIH  A 500 (-2.9A)
DIH  A 500 (-3.3A)
None
 0.40A 5i3cC-3of3A:
41.5		 5i3cC-3of3A:
80.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2p4s PURINE NUCLEOSIDE
PHOSPHORYLASE
(Anopheles
gambiae) 		5 / 12 GLU A 174
PRO A 283
GLU A 286
THR A 327
GLY A 203
 None
None
DIH  A 401 (-2.8A)
DIH  A 401 (-4.2A)
DIH  A 401 (-3.4A)
 1.20A 5xioA-2p4sA:
2.4		 5xioA-2p4sA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3of3 PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE 1
(Vibrio
cholerae) 		5 / 9 SER A 104
GLY A 106
VAL A 192
GLU A 193
MET A 194
 PO4  A 501 ( 2.7A)
DIH  A 500 (-4.0A)
DIH  A 500 (-4.8A)
None
DIH  A 500 (-3.8A)
 0.33A 5zncA-3of3A:
17.6		 5zncA-3of3A:
27.95