SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DI6'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		5 / 12 HIS A  72
HIS A  74
HIS A 242
HIS A 265
ASP A 317
 FE  A 500 (-3.4A)
FE  A 500 (-3.2A)
FE  A 500 ( 3.5A)
DI6  A 600 ( 4.7A)
FE  A 500 (-2.9A)
 0.62A 1a4lA-2q09A:
19.8		 1a4lA-2q09A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		5 / 12 HIS A  72
HIS A  74
HIS A 242
HIS A 265
ASP A 317
 FE  A 500 (-3.4A)
FE  A 500 (-3.2A)
FE  A 500 ( 3.5A)
DI6  A 600 ( 4.7A)
FE  A 500 (-2.9A)
 0.55A 1a4lC-2q09A:
19.8		 1a4lC-2q09A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		4 / 6 THR A 322
GLN A 245
PHE A 214
HIS A 177
 DI6  A 600 (-2.8A)
DI6  A 600 (-3.0A)
DI6  A 600 (-3.5A)
DI6  A 600 (-3.9A)
 0.97A 1tt0C-2q09A:
undetectable		 1tt0C-2q09A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		4 / 6 THR A 322
GLN A 245
PHE A 214
HIS A 177
 DI6  A 600 (-2.8A)
DI6  A 600 (-3.0A)
DI6  A 600 (-3.5A)
DI6  A 600 (-3.9A)
 0.98A 1tt0D-2q09A:
undetectable		 1tt0D-2q09A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		5 / 12 HIS A  72
HIS A  74
HIS A 242
HIS A 265
ASP A 317
 FE  A 500 (-3.4A)
FE  A 500 (-3.2A)
FE  A 500 ( 3.5A)
DI6  A 600 ( 4.7A)
FE  A 500 (-2.9A)
 0.49A 2pgrA-2q09A:
20.5		 2pgrA-2q09A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2q09 IMIDAZOLONEPROPIONAS
E
(unidentified) 		5 / 12 HIS A  74
HIS A 242
HIS A 265
LEU A 294
ASP A 317
 FE  A 500 (-3.2A)
FE  A 500 ( 3.5A)
DI6  A 600 ( 4.7A)
None
FE  A 500 (-2.9A)
 0.82A 4r88A-2q09A:
36.5		 4r88A-2q09A:
25.67