SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DGP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 10 VAL A  79
ILE A 122
LEU A  90
LEU A 142
GLY A 139
 None
None
None
None
DGP  A 301 (-3.4A)
 1.10A 2xf3A-1delA:
0.0		 2xf3A-1delA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 8 LYS A  37
ARG A 132
ARG A  68
ASP A  15
 DGP  A 301 (-2.7A)
DGP  A 301 (-3.6A)
DGP  A 301 (-3.3A)
None
 1.37A 4kr4C-1delA:
0.0		 4kr4C-1delA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2lrr DNA-BINDING PROTEIN
SMUBP-2
(Homo
sapiens) 		4 / 5 HIS A 753
HIS A 769
LEU A 744
VAL A 782
 None
DGP  A 801 (-4.4A)
None
None
 1.16A 6bc9A-2lrrA:
undetectable		 6bc9A-2lrrA:
25.53