SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DGL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 ILE A 214
LEU A  66
ASP A   7
GLY A  12
ALA A  73
 None
None
DGL  A1256 (-3.5A)
None
None
 1.05A 1b02A-2w4iA:
undetectable		 1b02A-2w4iA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A  40
ALA A  73
ILE A  47
GLY A 180
THR A 182
 DGL  A1256 (-3.4A)
None
None
None
DGL  A1256 (-3.1A)
 1.08A 1c9sN-2w4iA:
undetectable
1c9sO-2w4iA:
undetectable		 1c9sN-2w4iA:
14.79
1c9sO-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.02A 1c9sP-1zuwA:
undetectable
1c9sQ-1zuwA:
undetectable		 1c9sP-1zuwA:
13.97
1c9sQ-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.00A 1c9sP-2dwuA:
undetectable
1c9sQ-2dwuA:
undetectable		 1c9sP-2dwuA:
16.50
1c9sQ-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.01A 1c9sP-2gzmA:
undetectable
1c9sQ-2gzmA:
undetectable		 1c9sP-2gzmA:
13.75
1c9sQ-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.01A 1c9sP-2jfqA:
undetectable
1c9sQ-2jfqA:
undetectable		 1c9sP-2jfqA:
16.22
1c9sQ-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.02A 1c9sP-2vvtA:
undetectable
1c9sQ-2vvtA:
undetectable		 1c9sP-2vvtA:
12.76
1c9sQ-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 GLY A  40
ALA A  73
ILE A  47
GLY A 180
THR A 182
 DGL  A1256 (-3.4A)
None
None
None
DGL  A1256 (-3.1A)
 1.10A 1c9sP-2w4iA:
undetectable
1c9sQ-2w4iA:
undetectable		 1c9sP-2w4iA:
14.79
1c9sQ-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.03A 1c9sP-2w4iA:
undetectable
1c9sQ-2w4iA:
undetectable		 1c9sP-2w4iA:
14.79
1c9sQ-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.02A 1c9sP-3outA:
undetectable
1c9sQ-3outA:
undetectable		 1c9sP-3outA:
12.83
1c9sQ-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.04A 1c9sP-5hj7A:
undetectable
1c9sQ-5hj7A:
undetectable		 1c9sP-5hj7A:
16.27
1c9sQ-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.04A 1c9sP-5ijwA:
undetectable
1c9sQ-5ijwA:
undetectable		 1c9sP-5ijwA:
14.49
1c9sQ-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.06A 1c9sP-5w16A:
undetectable
1c9sQ-5w16A:
undetectable		 1c9sP-5w16A:
undetectable
1c9sQ-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 9 GLY A 187
THR A 189
ALA A  80
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
None
None
DGL  A 278 (-3.6A)
 0.91A 1gtfD-2dwuA:
undetectable
1gtfE-2dwuA:
undetectable		 1gtfD-2dwuA:
16.50
1gtfE-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 9 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
None
None
DGL  A 501 (-3.6A)
 0.93A 1gtfD-2gzmA:
undetectable
1gtfE-2gzmA:
undetectable		 1gtfD-2gzmA:
13.75
1gtfE-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 9 GLY A 183
THR A 185
ALA A  75
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
None
None
DGL  A1267 (-3.7A)
 0.92A 1gtfD-2jfqA:
undetectable
1gtfE-2jfqA:
undetectable		 1gtfD-2jfqA:
16.22
1gtfE-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 9 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.91A 1gtfD-2vvtA:
undetectable
1gtfE-2vvtA:
undetectable		 1gtfD-2vvtA:
12.76
1gtfE-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 1gtfJ-1zuwA:
undetectable
1gtfK-1zuwA:
undetectable		 1gtfJ-1zuwA:
13.97
1gtfK-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
ALA A  80
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
None
None
DGL  A 278 (-3.6A)
 0.98A 1gtfJ-2dwuA:
undetectable
1gtfK-2dwuA:
undetectable		 1gtfJ-2dwuA:
16.50
1gtfK-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 1gtfJ-2dwuA:
undetectable
1gtfK-2dwuA:
undetectable		 1gtfJ-2dwuA:
16.50
1gtfK-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
None
None
DGL  A 501 (-3.6A)
 0.99A 1gtfJ-2gzmA:
undetectable
1gtfK-2gzmA:
undetectable		 1gtfJ-2gzmA:
13.75
1gtfK-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 1gtfJ-2gzmA:
undetectable
1gtfK-2gzmA:
undetectable		 1gtfJ-2gzmA:
13.75
1gtfK-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
ALA A  75
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
None
None
DGL  A1267 (-3.7A)
 0.99A 1gtfJ-2jfqA:
undetectable
1gtfK-2jfqA:
undetectable		 1gtfJ-2jfqA:
16.22
1gtfK-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 1gtfJ-2jfqA:
undetectable
1gtfK-2jfqA:
undetectable		 1gtfJ-2jfqA:
16.22
1gtfK-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.98A 1gtfJ-2vvtA:
undetectable
1gtfK-2vvtA:
undetectable		 1gtfJ-2vvtA:
12.76
1gtfK-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.11A 1gtfJ-2vvtA:
undetectable
1gtfK-2vvtA:
undetectable		 1gtfJ-2vvtA:
12.76
1gtfK-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 1gtfJ-2w4iA:
undetectable
1gtfK-2w4iA:
undetectable		 1gtfJ-2w4iA:
14.79
1gtfK-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 1gtfJ-3outA:
undetectable
1gtfK-3outA:
undetectable		 1gtfJ-3outA:
12.83
1gtfK-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 1gtfJ-5hj7A:
undetectable
1gtfK-5hj7A:
undetectable		 1gtfJ-5hj7A:
16.27
1gtfK-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.13A 1gtfJ-5ijwA:
undetectable
1gtfK-5ijwA:
undetectable		 1gtfJ-5ijwA:
14.49
1gtfK-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 1gtfJ-5w16A:
undetectable
1gtfK-5w16A:
undetectable		 1gtfJ-5w16A:
undetectable
1gtfK-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.01A 1gtfQ-1zuwA:
undetectable
1gtfR-1zuwA:
undetectable		 1gtfQ-1zuwA:
13.97
1gtfR-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.00A 1gtfQ-2dwuA:
undetectable
1gtfR-2dwuA:
undetectable		 1gtfQ-2dwuA:
16.50
1gtfR-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.01A 1gtfQ-2gzmA:
undetectable
1gtfR-2gzmA:
undetectable		 1gtfQ-2gzmA:
13.75
1gtfR-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.01A 1gtfQ-2jfqA:
undetectable
1gtfR-2jfqA:
undetectable		 1gtfQ-2jfqA:
16.22
1gtfR-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.02A 1gtfQ-2vvtA:
undetectable
1gtfR-2vvtA:
undetectable		 1gtfQ-2vvtA:
12.76
1gtfR-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.02A 1gtfQ-2w4iA:
undetectable
1gtfR-2w4iA:
undetectable		 1gtfQ-2w4iA:
14.79
1gtfR-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.01A 1gtfQ-3outA:
undetectable
1gtfR-3outA:
undetectable		 1gtfQ-3outA:
12.83
1gtfR-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.04A 1gtfQ-5hj7A:
undetectable
1gtfR-5hj7A:
undetectable		 1gtfQ-5hj7A:
16.27
1gtfR-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.04A 1gtfQ-5ijwA:
undetectable
1gtfR-5ijwA:
undetectable		 1gtfQ-5ijwA:
14.49
1gtfR-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.05A 1gtfQ-5w16A:
undetectable
1gtfR-5w16A:
undetectable		 1gtfQ-5w16A:
undetectable
1gtfR-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.03A 1gtfS-1zuwA:
undetectable
1gtfT-1zuwA:
undetectable		 1gtfS-1zuwA:
13.97
1gtfT-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.01A 1gtfS-2dwuA:
undetectable
1gtfT-2dwuA:
undetectable		 1gtfS-2dwuA:
16.50
1gtfT-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.02A 1gtfS-2gzmA:
undetectable
1gtfT-2gzmA:
undetectable		 1gtfS-2gzmA:
13.75
1gtfT-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.02A 1gtfS-2jfqA:
undetectable
1gtfT-2jfqA:
undetectable		 1gtfS-2jfqA:
16.22
1gtfT-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.03A 1gtfS-2vvtA:
undetectable
1gtfT-2vvtA:
undetectable		 1gtfS-2vvtA:
12.76
1gtfT-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.04A 1gtfS-2w4iA:
undetectable
1gtfT-2w4iA:
undetectable		 1gtfS-2w4iA:
14.79
1gtfT-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.04A 1gtfS-3outA:
undetectable
1gtfT-3outA:
undetectable		 1gtfS-3outA:
12.83
1gtfT-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.06A 1gtfS-5hj7A:
undetectable
1gtfT-5hj7A:
undetectable		 1gtfS-5hj7A:
16.27
1gtfT-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.05A 1gtfS-5ijwA:
undetectable
1gtfT-5ijwA:
undetectable		 1gtfS-5ijwA:
14.49
1gtfT-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.07A 1gtfS-5w16A:
undetectable
1gtfT-5w16A:
undetectable		 1gtfS-5w16A:
undetectable
1gtfT-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.05A 1gtnT-1zuwA:
undetectable
1gtnU-1zuwA:
undetectable		 1gtnT-1zuwA:
13.97
1gtnU-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.03A 1gtnT-2dwuA:
undetectable
1gtnU-2dwuA:
undetectable		 1gtnT-2dwuA:
16.50
1gtnU-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.04A 1gtnT-2gzmA:
undetectable
1gtnU-2gzmA:
undetectable		 1gtnT-2gzmA:
13.75
1gtnU-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.04A 1gtnT-2jfqA:
undetectable
1gtnU-2jfqA:
undetectable		 1gtnT-2jfqA:
16.22
1gtnU-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.05A 1gtnT-2vvtA:
undetectable
1gtnU-2vvtA:
undetectable		 1gtnT-2vvtA:
12.76
1gtnU-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.05A 1gtnT-2w4iA:
undetectable
1gtnU-2w4iA:
undetectable		 1gtnT-2w4iA:
14.79
1gtnU-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.05A 1gtnT-3outA:
undetectable
1gtnU-3outA:
undetectable		 1gtnT-3outA:
12.83
1gtnU-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.07A 1gtnT-5hj7A:
undetectable
1gtnU-5hj7A:
undetectable		 1gtnT-5hj7A:
16.27
1gtnU-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.06A 1gtnT-5ijwA:
undetectable
1gtnU-5ijwA:
undetectable		 1gtnT-5ijwA:
14.49
1gtnU-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.08A 1gtnT-5w16A:
undetectable
1gtnU-5w16A:
undetectable		 1gtnT-5w16A:
undetectable
1gtnU-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 GLY A 187
THR A 189
ALA A  80
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
None
None
DGL  A 278 (-3.6A)
 0.95A 1gtnL-2dwuA:
undetectable
1gtnV-2dwuA:
undetectable		 1gtnL-2dwuA:
16.50
1gtnV-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 7 ASP A 237
SER A 257
TRP A 228
ALA A 229
 DGL  A 502 ( 3.7A)
DGL  A 502 (-2.8A)
ALA  A 501 ( 3.7A)
ALA  A 501 ( 3.8A)
 1.00A 1gxsA-3h41A:
undetectable
1gxsB-3h41A:
undetectable		 1gxsA-3h41A:
20.00
1gxsB-3h41A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 8 GLU A  62
THR A  89
TYR A  92
ILE A  66
 None
DGL  A 301 (-4.0A)
None
None
 1.13A 1qvtA-5xniA:
undetectable		 1qvtA-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 1qzfA-5xniA:
undetectable		 1qzfA-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 1qzfB-5xniA:
undetectable		 1qzfB-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 1qzfC-5xniA:
undetectable		 1qzfC-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 1qzfD-5xniA:
undetectable		 1qzfD-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 1qzfE-5xniA:
undetectable		 1qzfE-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 12 GLY A 117
THR A 186
VAL A 149
GLU A 153
PRO A  44
 None
DGL  A1301 (-3.1A)
None
None
None
 1.25A 1sg9A-1zuwA:
2.3		 1sg9A-1zuwA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 GLY A 117
THR A 186
VAL A 149
GLU A 153
PRO A  45
 None
DGL  A 501 (-3.0A)
None
None
None
 1.22A 1sg9A-2gzmA:
4.0		 1sg9A-2gzmA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 12 GLY A 115
THR A 185
VAL A 147
GLU A 151
PRO A  43
 None
DGL  A1267 (-2.8A)
None
None
None
 1.20A 1sg9A-2jfqA:
3.6		 1sg9A-2jfqA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.06A 1utdE-1zuwA:
undetectable
1utdF-1zuwA:
undetectable		 1utdE-1zuwA:
13.97
1utdF-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.06A 1utdE-2dwuA:
undetectable
1utdF-2dwuA:
undetectable		 1utdE-2dwuA:
16.50
1utdF-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.06A 1utdE-2gzmA:
undetectable
1utdF-2gzmA:
undetectable		 1utdE-2gzmA:
13.75
1utdF-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.06A 1utdE-2jfqA:
undetectable
1utdF-2jfqA:
undetectable		 1utdE-2jfqA:
16.22
1utdF-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.07A 1utdE-2vvtA:
undetectable
1utdF-2vvtA:
undetectable		 1utdE-2vvtA:
12.76
1utdF-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.07A 1utdE-2w4iA:
undetectable
1utdF-2w4iA:
undetectable		 1utdE-2w4iA:
14.79
1utdF-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.05A 1utdE-3outA:
undetectable
1utdF-3outA:
undetectable		 1utdE-3outA:
12.83
1utdF-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.09A 1utdE-5hj7A:
undetectable
1utdF-5hj7A:
undetectable		 1utdE-5hj7A:
16.27
1utdF-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.09A 1utdE-5ijwA:
undetectable
1utdF-5ijwA:
undetectable		 1utdE-5ijwA:
14.49
1utdF-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.12A 1utdE-5w16A:
undetectable
1utdF-5w16A:
undetectable		 1utdE-5w16A:
undetectable
1utdF-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.06A 1utdH-1zuwA:
undetectable
1utdI-1zuwA:
undetectable		 1utdH-1zuwA:
13.97
1utdI-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 ALA A  80
THR A 124
THR A 121
GLY A 187
THR A 189
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 0.95A 1utdH-2dwuA:
undetectable
1utdI-2dwuA:
undetectable		 1utdH-2dwuA:
16.50
1utdI-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.05A 1utdH-2dwuA:
undetectable
1utdI-2dwuA:
undetectable		 1utdH-2dwuA:
16.50
1utdI-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 0.97A 1utdH-2gzmA:
undetectable
1utdI-2gzmA:
undetectable		 1utdH-2gzmA:
13.75
1utdI-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.06A 1utdH-2gzmA:
undetectable
1utdI-2gzmA:
undetectable		 1utdH-2gzmA:
13.75
1utdI-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 ALA A  75
THR A 119
THR A 116
GLY A 183
THR A 185
 None
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 0.96A 1utdH-2jfqA:
undetectable
1utdI-2jfqA:
undetectable		 1utdH-2jfqA:
16.22
1utdI-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.05A 1utdH-2jfqA:
undetectable
1utdI-2jfqA:
undetectable		 1utdH-2jfqA:
16.22
1utdI-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.96A 1utdH-2vvtA:
undetectable
1utdI-2vvtA:
undetectable		 1utdH-2vvtA:
12.76
1utdI-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.07A 1utdH-2vvtA:
undetectable
1utdI-2vvtA:
undetectable		 1utdH-2vvtA:
12.76
1utdI-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.07A 1utdH-2w4iA:
undetectable
1utdI-2w4iA:
undetectable		 1utdH-2w4iA:
14.79
1utdI-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.05A 1utdH-3outA:
undetectable
1utdI-3outA:
undetectable		 1utdH-3outA:
12.83
1utdI-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.09A 1utdH-5hj7A:
undetectable
1utdI-5hj7A:
undetectable		 1utdH-5hj7A:
16.27
1utdI-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.08A 1utdH-5ijwA:
undetectable
1utdI-5ijwA:
undetectable		 1utdH-5ijwA:
14.49
1utdI-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.11A 1utdH-5w16A:
undetectable
1utdI-5w16A:
undetectable		 1utdH-5w16A:
undetectable
1utdI-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 ALA A  80
THR A 124
THR A 121
GLY A 187
THR A 189
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 0.96A 1utdL-2dwuA:
undetectable
1utdM-2dwuA:
undetectable		 1utdL-2dwuA:
16.50
1utdM-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 0.99A 1utdL-2gzmA:
undetectable
1utdM-2gzmA:
undetectable		 1utdL-2gzmA:
13.75
1utdM-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 12 ALA A  75
THR A 119
THR A 116
GLY A 183
THR A 185
 None
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 0.98A 1utdL-2jfqA:
undetectable
1utdM-2jfqA:
undetectable		 1utdL-2jfqA:
16.22
1utdM-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 12 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.98A 1utdL-2vvtA:
undetectable
1utdM-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdM-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.03A 1utdO-2dwuA:
undetectable
1utdP-2dwuA:
undetectable		 1utdO-2dwuA:
16.50
1utdP-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 ALA A  80
THR A 124
THR A 121
GLY A 187
THR A 189
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 0.94A 1utdP-2dwuA:
undetectable
1utdQ-2dwuA:
undetectable		 1utdP-2dwuA:
16.50
1utdQ-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 0.97A 1utdP-2gzmA:
undetectable
1utdQ-2gzmA:
undetectable		 1utdP-2gzmA:
13.75
1utdQ-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 ALA A  75
THR A 119
THR A 116
GLY A 183
THR A 185
 None
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 0.96A 1utdP-2jfqA:
undetectable
1utdQ-2jfqA:
undetectable		 1utdP-2jfqA:
16.22
1utdQ-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 ALA A  77
THR A 121
THR A 118
GLY A 184
THR A 186
 None
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 0.96A 1utdP-2vvtA:
undetectable
1utdQ-2vvtA:
undetectable		 1utdP-2vvtA:
12.76
1utdQ-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
 1.03A 1utdS-1zuwA:
undetectable
1utdT-1zuwA:
undetectable		 1utdS-1zuwA:
13.97
1utdT-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 ALA A  80
THR A 124
THR A 121
GLY A 187
THR A 189
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 0.94A 1utdS-2dwuA:
undetectable
1utdT-2dwuA:
undetectable		 1utdS-2dwuA:
16.50
1utdT-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 190
THR A 124
THR A 121
GLY A 187
THR A 189
 DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
None
DGL  A 278 (-3.0A)
 1.02A 1utdS-2dwuA:
undetectable
1utdT-2dwuA:
undetectable		 1utdS-2dwuA:
16.50
1utdT-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
None
DGL  A 501 (-3.0A)
 1.03A 1utdS-2gzmA:
undetectable
1utdT-2gzmA:
undetectable		 1utdS-2gzmA:
13.75
1utdT-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 HIS A 186
THR A 119
THR A 116
GLY A 183
THR A 185
 DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
None
DGL  A1267 (-2.8A)
 1.03A 1utdS-2jfqA:
undetectable
1utdT-2jfqA:
undetectable		 1utdS-2jfqA:
16.22
1utdT-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
 I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
None
DGL  A1270 (-3.0A)
 1.04A 1utdS-2vvtA:
undetectable
1utdT-2vvtA:
undetectable		 1utdS-2vvtA:
12.76
1utdT-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 HIS A 183
THR A 119
THR A 116
GLY A 180
THR A 182
 DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
None
DGL  A1256 (-3.1A)
 1.04A 1utdS-2w4iA:
undetectable
1utdT-2w4iA:
undetectable		 1utdS-2w4iA:
14.79
1utdT-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 HIS A 185
THR A 119
THR A 116
GLY A 182
THR A 184
 DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
None
DGL  A 266 (-3.3A)
 1.03A 1utdS-3outA:
undetectable
1utdT-3outA:
undetectable		 1utdS-3outA:
12.83
1utdT-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A 187
THR A 122
THR A 119
GLY A 184
THR A 186
 DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
None
DGL  A 301 (-2.9A)
 1.06A 1utdS-5hj7A:
undetectable
1utdT-5hj7A:
undetectable		 1utdS-5hj7A:
16.27
1utdT-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.06A 1utdS-5ijwA:
undetectable
1utdT-5ijwA:
undetectable		 1utdS-5ijwA:
14.49
1utdT-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 HIS A 178
THR A 119
THR A 116
GLY A 175
THR A 177
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-2.9A)
 1.08A 1utdS-5w16A:
undetectable
1utdT-5w16A:
undetectable		 1utdS-5w16A:
undetectable
1utdT-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.05A 1utdL-1zuwA:
undetectable
1utdV-1zuwA:
undetectable		 1utdL-1zuwA:
13.97
1utdV-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A 187
THR A 189
ALA A  80
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
None
None
DGL  A 278 (-3.6A)
 0.97A 1utdL-2dwuA:
undetectable
1utdV-2dwuA:
undetectable		 1utdL-2dwuA:
16.50
1utdV-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.04A 1utdL-2dwuA:
undetectable
1utdV-2dwuA:
undetectable		 1utdL-2dwuA:
16.50
1utdV-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
None
None
DGL  A 501 (-3.6A)
 0.99A 1utdL-2gzmA:
undetectable
1utdV-2gzmA:
undetectable		 1utdL-2gzmA:
13.75
1utdV-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.05A 1utdL-2gzmA:
undetectable
1utdV-2gzmA:
undetectable		 1utdL-2gzmA:
13.75
1utdV-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 GLY A 183
THR A 185
ALA A  75
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
None
None
DGL  A1267 (-3.7A)
 0.98A 1utdL-2jfqA:
undetectable
1utdV-2jfqA:
undetectable		 1utdL-2jfqA:
16.22
1utdV-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.05A 1utdL-2jfqA:
undetectable
1utdV-2jfqA:
undetectable		 1utdL-2jfqA:
16.22
1utdV-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 GLY A 184
THR A 186
ALA A  77
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
None
None
DGL  A1270 (-3.6A)
 0.98A 1utdL-2vvtA:
undetectable
1utdV-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdV-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.06A 1utdL-2vvtA:
undetectable
1utdV-2vvtA:
undetectable		 1utdL-2vvtA:
12.76
1utdV-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 11 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.07A 1utdL-2w4iA:
undetectable
1utdV-2w4iA:
undetectable		 1utdL-2w4iA:
14.79
1utdV-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 11 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.06A 1utdL-3outA:
undetectable
1utdV-3outA:
undetectable		 1utdL-3outA:
12.83
1utdV-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.08A 1utdL-5hj7A:
undetectable
1utdV-5hj7A:
undetectable		 1utdL-5hj7A:
16.27
1utdV-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.08A 1utdL-5ijwA:
undetectable
1utdV-5ijwA:
undetectable		 1utdL-5ijwA:
14.49
1utdV-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 11 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.10A 1utdL-5w16A:
undetectable
1utdV-5w16A:
undetectable		 1utdL-5w16A:
undetectable
1utdV-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.15A 2oipA-5xniA:
undetectable		 2oipA-5xniA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.17A 2oipD-5xniA:
undetectable		 2oipD-5xniA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ijl MUCONATE
CYCLOISOMERASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A 327
SER A  90
ALA A 139
LEU A 299
ALA A 333
 DGL  A 385 ( 3.6A)
None
None
None
None
 1.29A 2wscB-3ijlA:
undetectable		 2wscB-3ijlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ijl MUCONATE
CYCLOISOMERASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A 327
SER A  90
ALA A 139
LEU A 299
ALA A 333
 DGL  A 385 ( 3.6A)
None
None
None
None
 1.29A 2wseB-3ijlA:
undetectable		 2wseB-3ijlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ijl MUCONATE
CYCLOISOMERASE
(Bacteroides
thetaiotaomicron) 		5 / 9 MET A 327
SER A  90
ALA A 139
LEU A 299
ALA A 333
 DGL  A 385 ( 3.6A)
None
None
None
None
 1.29A 2wsfB-3ijlA:
undetectable		 2wsfB-3ijlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 12 ILE A 181
SER A 177
GLY A 140
TYR A 125
ASN A  73
 None
None
None
None
DGL  A1267 (-4.3A)
 1.14A 2zw9A-2jfqA:
undetectable		 2zw9A-2jfqA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		4 / 8 VAL A  37
LEU A  13
TYR A  30
HIS A 182
 DGL  A 260 ( 4.8A)
None
None
DGL  A 260 (-4.3A)
 1.04A 3af0A-3uhoA:
undetectable		 3af0A-3uhoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		4 / 8 VAL A  42
LEU A  18
TYR A  35
HIS A 178
 NO3  A 302 (-4.9A)
None
None
DGL  A 301 ( 3.9A)
 1.00A 3af0A-5w16A:
undetectable		 3af0A-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A  18
GLY A  16
ASP A  14
ALA A  76
ALA A 152
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 ( 4.4A)
 1.10A 3g88A-2dwuA:
undetectable		 3g88A-2dwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A  18
GLY A  16
ASP A  14
ALA A  76
ALA A 152
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 ( 4.4A)
 1.09A 3g88B-2dwuA:
undetectable		 3g88B-2dwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 12 GLY A  18
GLY A  16
ASP A  14
ALA A  76
ALA A 152
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 ( 4.4A)
 1.08A 3g89A-2dwuA:
undetectable		 3g89A-2dwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 11 GLY A  18
GLY A  16
ASP A  14
ALA A  76
ALA A 152
 None
None
DGL  A 278 (-3.6A)
None
DGL  A 278 ( 4.4A)
 1.08A 3g89B-2dwuA:
undetectable		 3g89B-2dwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.15A 3hj3B-5xniA:
undetectable		 3hj3B-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.12A 3hj3D-5xniA:
undetectable		 3hj3D-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 250
HIS A 187
SER A  77
ARG A 154
PRO A  46
 None
DGL  A 301 ( 4.4A)
DGL  A 301 (-2.7A)
None
None
 1.28A 3j6pB-5hj7A:
undetectable		 3j6pB-5hj7A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		4 / 8 ASN A  75
THR A  78
LEU A  82
ALA A 126
 DGL  A 501 (-4.0A)
None
None
None
 0.96A 3kp6A-2gzmA:
undetectable		 3kp6A-2gzmA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 9 ASN A  75
THR A  78
ALA A  79
LEU A  82
ALA A 126
 DGL  A 501 (-4.0A)
None
None
None
None
 1.11A 3kp6B-2gzmA:
undetectable		 3kp6B-2gzmA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 9 ASN A  73
THR A  76
ALA A  77
LEU A  80
ALA A 124
 DGL  A1267 (-4.3A)
None
None
None
None
 1.22A 3kp6B-2jfqA:
undetectable		 3kp6B-2jfqA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ijl MUCONATE
CYCLOISOMERASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A 327
SER A  90
ALA A 139
LEU A 299
ALA A 333
 DGL  A 385 ( 3.6A)
None
None
None
None
 1.32A 3lw5B-3ijlA:
undetectable		 3lw5B-3ijlA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 12 GLY A 180
ASN A  71
ALA A 188
LEU A 112
LEU A 207
 None
DGL  A1256 (-4.0A)
None
None
None
 1.07A 3p2kC-2w4iA:
undetectable		 3p2kC-2w4iA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 9 THR A 242
ASN A  41
GLY A  39
ASP A  14
LEU A  65
 None
None
None
DGL  A 278 (-3.6A)
None
 1.41A 3sfuB-2dwuA:
undetectable		 3sfuB-2dwuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 VAL A  96
ASN A  75
ALA A  77
THR A  54
ILE A   9
 None
DGL  A1301 (-4.1A)
None
None
None
 1.37A 3t3qD-1zuwA:
undetectable		 3t3qD-1zuwA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 12 ILE A  93
ASN A  71
TYR A 125
SER A 210
LEU A  19
 None
DGL  A1256 (-4.0A)
None
None
None
 1.15A 4a84A-2w4iA:
undetectable		 4a84A-2w4iA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 ILE A  93
ASN A  71
TYR A 125
SER A 203
LEU A  19
 None
DGL  A 260 (-4.1A)
None
None
None
 1.11A 4a84A-3uhoA:
undetectable		 4a84A-3uhoA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 12 THR A 182
PHE A  25
VAL A   5
ALA A  22
VAL A 215
 DGL  A1256 (-3.1A)
None
None
None
None
 1.14A 4df3A-2w4iA:
3.3		 4df3A-2w4iA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 THR A 181
PHE A  25
VAL A   5
ALA A  22
VAL A 208
 DGL  A 260 (-3.0A)
None
None
None
None
 1.15A 4df3A-3uhoA:
undetectable		 4df3A-3uhoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 12 THR A 182
PHE A  25
VAL A   5
ALA A  22
VAL A 215
 DGL  A1256 (-3.1A)
None
None
None
None
 1.10A 4df3B-2w4iA:
2.0		 4df3B-2w4iA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 THR A 181
PHE A  25
VAL A   5
ALA A  22
VAL A 208
 DGL  A 260 (-3.0A)
None
None
None
None
 1.12A 4df3B-3uhoA:
2.5		 4df3B-3uhoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		4 / 8 SER A 143
CYH A  70
THR A  72
GLY A 180
 None
DGL  A1256 (-3.1A)
DGL  A1256 (-3.8A)
None
 0.78A 4fo4A-2w4iA:
undetectable		 4fo4A-2w4iA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		4 / 8 SER A 143
CYH A  70
THR A  72
GLY A 180
 None
DGL  A1256 (-3.1A)
DGL  A1256 (-3.8A)
None
 0.77A 4fo4B-2w4iA:
undetectable		 4fo4B-2w4iA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 11 ILE A 207
LEU A  66
ASP A   7
GLY A  12
ALA A  73
 None
None
DGL  A 260 (-3.3A)
None
None
 1.11A 4fogD-3uhoA:
undetectable		 4fogD-3uhoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 12 SER A  12
CYH A  74
PRO A  42
ALA A 118
GLY A 144
 DGL  A 266 (-2.8A)
DGL  A 266 ( 3.7A)
DGL  A 266 (-4.5A)
None
None
 0.96A 4j7xA-3outA:
undetectable		 4j7xA-3outA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 12 SER A  12
CYH A  74
PRO A  42
ALA A 118
GLY A 144
 DGL  A 266 (-2.8A)
DGL  A 266 ( 3.7A)
DGL  A 266 (-4.5A)
None
None
 0.98A 4j7xB-3outA:
undetectable		 4j7xB-3outA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.11A 4ky8A-5xniA:
undetectable		 4ky8A-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.13A 4ky8B-5xniA:
undetectable		 4ky8B-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.14A 4ky8D-5xniA:
undetectable		 4ky8D-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.10A 4ky8E-5xniA:
undetectable		 4ky8E-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		3 / 3 ASP A  14
VAL A  62
ASN A  41
 DGL  A 278 (-3.6A)
None
None
 0.54A 4lmnA-2dwuA:
undetectable		 4lmnA-2dwuA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		3 / 3 HIS A 178
TRP A 149
SER A  13
 DGL  A 301 ( 3.9A)
None
DGL  A 301 (-2.6A)
 1.17A 4lrhD-5w16A:
undetectable		 4lrhD-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		4 / 5 ASN A  76
GLY A 175
ASP A 150
ASP A 197
 DGL  A 301 (-4.3A)
None
None
None
 1.13A 4n48B-5w16A:
undetectable		 4n48B-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 5 GLY A  15
ASP A  11
GLU A  22
VAL A 216
 I24  A1269 ( 3.8A)
DGL  A1270 (-3.4A)
None
None
 0.95A 4nkvD-2vvtA:
undetectable		 4nkvD-2vvtA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A  14
ASP A  12
GLU A 243
VAL A  68
 None
DGL  A 301 (-3.3A)
None
None
 1.17A 4nkvD-5ijwA:
undetectable		 4nkvD-5ijwA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_A_MTXA604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.16A 4q0dA-5xniA:
undetectable		 4q0dA-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_B_MTXB604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.15A 4q0dB-5xniA:
undetectable		 4q0dB-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_E_MTXE604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 12 LEU A 182
LEU A 126
SER A 195
ILE A 175
LEU A 166
 None
None
DGL  A 301 (-2.8A)
None
None
 1.16A 4q0dE-5xniA:
undetectable		 4q0dE-5xniA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.48A 4qvlV-1zuwA:
undetectable
4qvlb-1zuwA:
undetectable		 4qvlV-1zuwA:
21.83
4qvlb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.39A 4qvlV-2jfqA:
undetectable
4qvlb-2jfqA:
undetectable		 4qvlV-2jfqA:
19.42
4qvlb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.47A 4qvlH-1zuwA:
undetectable
4qvlN-1zuwA:
undetectable		 4qvlH-1zuwA:
21.83
4qvlN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.50A 4qvlH-2jfqA:
undetectable
4qvlN-2jfqA:
undetectable		 4qvlH-2jfqA:
19.42
4qvlN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.38A 4qvlH-2jfqA:
undetectable
4qvlN-2jfqA:
undetectable		 4qvlH-2jfqA:
19.42
4qvlN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.45A 4qvmV-1zuwA:
undetectable
4qvmb-1zuwA:
undetectable		 4qvmV-1zuwA:
21.83
4qvmb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qvmV-2jfqA:
undetectable
4qvmb-2jfqA:
undetectable		 4qvmV-2jfqA:
19.42
4qvmb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.37A 4qvmV-2jfqA:
undetectable
4qvmb-2jfqA:
undetectable		 4qvmV-2jfqA:
19.42
4qvmb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.44A 4qvmH-1zuwA:
undetectable
4qvmN-1zuwA:
undetectable		 4qvmH-1zuwA:
21.83
4qvmN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.47A 4qvmH-2jfqA:
undetectable
4qvmN-2jfqA:
undetectable		 4qvmH-2jfqA:
19.42
4qvmN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.36A 4qvmH-2jfqA:
undetectable
4qvmN-2jfqA:
undetectable		 4qvmH-2jfqA:
19.42
4qvmN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.47A 4qvpV-1zuwA:
undetectable
4qvpb-1zuwA:
undetectable		 4qvpV-1zuwA:
21.83
4qvpb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.49A 4qvpV-2jfqA:
undetectable
4qvpb-2jfqA:
undetectable		 4qvpV-2jfqA:
19.42
4qvpb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.46A 4qvpH-1zuwA:
undetectable
4qvpN-1zuwA:
undetectable		 4qvpH-1zuwA:
21.83
4qvpN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qvpH-2jfqA:
undetectable
4qvpN-2jfqA:
undetectable		 4qvpH-2jfqA:
19.42
4qvpN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.46A 4qvqV-1zuwA:
undetectable
4qvqb-1zuwA:
undetectable		 4qvqV-1zuwA:
21.83
4qvqb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qvqV-2jfqA:
undetectable
4qvqb-2jfqA:
undetectable		 4qvqV-2jfqA:
19.42
4qvqb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.45A 4qvqH-1zuwA:
undetectable
4qvqN-1zuwA:
undetectable		 4qvqH-1zuwA:
21.83
4qvqN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qvqH-2jfqA:
undetectable
4qvqN-2jfqA:
undetectable		 4qvqH-2jfqA:
19.42
4qvqN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.44A 4qvwV-1zuwA:
undetectable
4qvwb-1zuwA:
undetectable		 4qvwV-1zuwA:
21.83
4qvwb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.47A 4qvwV-2jfqA:
undetectable
4qvwb-2jfqA:
undetectable		 4qvwV-2jfqA:
19.42
4qvwb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.36A 4qvwV-2jfqA:
undetectable
4qvwb-2jfqA:
undetectable		 4qvwV-2jfqA:
19.42
4qvwb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.44A 4qvwH-1zuwA:
undetectable
4qvwN-1zuwA:
undetectable		 4qvwH-1zuwA:
21.83
4qvwN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.36A 4qvwH-2jfqA:
undetectable
4qvwN-2jfqA:
undetectable		 4qvwH-2jfqA:
19.42
4qvwN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.39A 4qw0V-2jfqA:
undetectable
4qw0b-2jfqA:
undetectable		 4qw0V-2jfqA:
19.42
4qw0b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.39A 4qw0H-2jfqA:
undetectable
4qw0N-2jfqA:
undetectable		 4qw0H-2jfqA:
19.42
4qw0N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.47A 4qw1V-1zuwA:
undetectable
4qw1b-1zuwA:
undetectable		 4qw1V-1zuwA:
21.83
4qw1b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.49A 4qw1V-2jfqA:
undetectable
4qw1b-2jfqA:
undetectable		 4qw1V-2jfqA:
19.42
4qw1b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.39A 4qw1V-2jfqA:
undetectable
4qw1b-2jfqA:
undetectable		 4qw1V-2jfqA:
19.42
4qw1b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.45A 4qw1H-1zuwA:
undetectable
4qw1N-1zuwA:
undetectable		 4qw1H-1zuwA:
21.83
4qw1N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qw1H-2jfqA:
undetectable
4qw1N-2jfqA:
undetectable		 4qw1H-2jfqA:
19.42
4qw1N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.38A 4qw1H-2jfqA:
undetectable
4qw1N-2jfqA:
undetectable		 4qw1H-2jfqA:
19.42
4qw1N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.46A 4qw3V-1zuwA:
undetectable
4qw3b-1zuwA:
undetectable		 4qw3V-1zuwA:
21.83
4qw3b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qw3V-2jfqA:
undetectable
4qw3b-2jfqA:
undetectable		 4qw3V-2jfqA:
19.42
4qw3b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.38A 4qw3V-2jfqA:
undetectable
4qw3b-2jfqA:
undetectable		 4qw3V-2jfqA:
19.42
4qw3b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.45A 4qw3H-1zuwA:
undetectable
4qw3N-1zuwA:
undetectable		 4qw3H-1zuwA:
21.83
4qw3N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.48A 4qw3H-2jfqA:
undetectable
4qw3N-2jfqA:
undetectable		 4qw3H-2jfqA:
19.42
4qw3N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.37A 4qw3H-2jfqA:
undetectable
4qw3N-2jfqA:
undetectable		 4qw3H-2jfqA:
19.42
4qw3N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.49A 4qwuV-1zuwA:
undetectable
4qwub-1zuwA:
undetectable		 4qwuV-1zuwA:
21.83
4qwub-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.49A 4qwuH-1zuwA:
undetectable
4qwuN-1zuwA:
undetectable		 4qwuH-1zuwA:
21.83
4qwuN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.46A 5bxnV-2jfqA:
undetectable
5bxnb-2jfqA:
undetectable		 5bxnV-2jfqA:
19.74
5bxnb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.45A 5bxnH-2jfqA:
undetectable
5bxnN-2jfqA:
undetectable		 5bxnH-2jfqA:
19.74
5bxnN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.45A 5cz7H-1zuwA:
undetectable
5cz7N-1zuwA:
undetectable		 5cz7H-1zuwA:
21.83
5cz7N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  13
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.47A 5cz7H-2jfqA:
undetectable
5cz7N-2jfqA:
undetectable		 5cz7H-2jfqA:
19.42
5cz7N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.47A 5d0xV-1zuwA:
undetectable
5d0xb-1zuwA:
undetectable		 5d0xV-1zuwA:
21.83
5d0xb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.38A 5d0xV-2jfqA:
undetectable
5d0xb-2jfqA:
undetectable		 5d0xV-2jfqA:
19.42
5d0xb-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.46A 5d0xH-1zuwA:
undetectable
5d0xN-1zuwA:
undetectable		 5d0xH-1zuwA:
21.83
5d0xN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.38A 5d0xH-2jfqA:
undetectable
5d0xN-2jfqA:
undetectable		 5d0xH-2jfqA:
19.42
5d0xN-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5eevA-1zuwA:
undetectable
5eevB-1zuwA:
undetectable		 5eevA-1zuwA:
13.97
5eevB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5eevA-2dwuA:
undetectable
5eevB-2dwuA:
undetectable		 5eevA-2dwuA:
16.50
5eevB-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5eevA-2gzmA:
undetectable
5eevB-2gzmA:
undetectable		 5eevA-2gzmA:
13.75
5eevB-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5eevA-2jfqA:
undetectable
5eevB-2jfqA:
undetectable		 5eevA-2jfqA:
16.22
5eevB-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eevA-2vvtA:
undetectable
5eevB-2vvtA:
undetectable		 5eevA-2vvtA:
12.76
5eevB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5eevA-2w4iA:
undetectable
5eevB-2w4iA:
undetectable		 5eevA-2w4iA:
14.79
5eevB-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5eevA-3outA:
undetectable
5eevB-3outA:
undetectable		 5eevA-3outA:
12.83
5eevB-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5eevA-5hj7A:
undetectable
5eevB-5hj7A:
undetectable		 5eevA-5hj7A:
16.27
5eevB-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eevA-5ijwA:
undetectable
5eevB-5ijwA:
undetectable		 5eevA-5ijwA:
14.49
5eevB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5eevA-5w16A:
undetectable
5eevB-5w16A:
undetectable		 5eevA-5w16A:
undetectable
5eevB-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5eewA-1zuwA:
undetectable
5eewB-1zuwA:
undetectable		 5eewA-1zuwA:
13.97
5eewB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5eewA-2dwuA:
undetectable
5eewB-2dwuA:
undetectable		 5eewA-2dwuA:
16.50
5eewB-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5eewA-2gzmA:
undetectable
5eewB-2gzmA:
undetectable		 5eewA-2gzmA:
13.75
5eewB-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5eewA-2jfqA:
undetectable
5eewB-2jfqA:
undetectable		 5eewA-2jfqA:
16.22
5eewB-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eewA-2vvtA:
undetectable
5eewB-2vvtA:
undetectable		 5eewA-2vvtA:
12.76
5eewB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5eewA-2w4iA:
undetectable
5eewB-2w4iA:
undetectable		 5eewA-2w4iA:
14.79
5eewB-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.09A 5eewA-3outA:
undetectable
5eewB-3outA:
undetectable		 5eewA-3outA:
12.83
5eewB-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5eewA-5hj7A:
undetectable
5eewB-5hj7A:
undetectable		 5eewA-5hj7A:
16.27
5eewB-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eewA-5ijwA:
undetectable
5eewB-5ijwA:
undetectable		 5eewA-5ijwA:
14.49
5eewB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5eewA-5w16A:
undetectable
5eewB-5w16A:
undetectable		 5eewA-5w16A:
undetectable
5eewB-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5eexA-1zuwA:
undetectable
5eexB-1zuwA:
undetectable		 5eexA-1zuwA:
13.97
5eexB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5eexA-2dwuA:
undetectable
5eexB-2dwuA:
undetectable		 5eexA-2dwuA:
16.50
5eexB-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5eexA-2gzmA:
undetectable
5eexB-2gzmA:
undetectable		 5eexA-2gzmA:
13.75
5eexB-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5eexA-2jfqA:
undetectable
5eexB-2jfqA:
undetectable		 5eexA-2jfqA:
16.22
5eexB-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eexA-2vvtA:
undetectable
5eexB-2vvtA:
undetectable		 5eexA-2vvtA:
12.76
5eexB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5eexA-2w4iA:
undetectable
5eexB-2w4iA:
undetectable		 5eexA-2w4iA:
14.79
5eexB-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.09A 5eexA-3outA:
undetectable
5eexB-3outA:
undetectable		 5eexA-3outA:
12.83
5eexB-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5eexA-5hj7A:
undetectable
5eexB-5hj7A:
undetectable		 5eexA-5hj7A:
16.27
5eexB-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eexA-5ijwA:
undetectable
5eexB-5ijwA:
undetectable		 5eexA-5ijwA:
14.49
5eexB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5eexA-5w16A:
undetectable
5eexB-5w16A:
undetectable		 5eexA-5w16A:
undetectable
5eexB-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5eeyA-1zuwA:
undetectable
5eeyB-1zuwA:
undetectable		 5eeyA-1zuwA:
13.97
5eeyB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5eeyA-2dwuA:
undetectable
5eeyB-2dwuA:
undetectable		 5eeyA-2dwuA:
16.50
5eeyB-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5eeyA-2gzmA:
undetectable
5eeyB-2gzmA:
undetectable		 5eeyA-2gzmA:
13.75
5eeyB-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5eeyA-2jfqA:
undetectable
5eeyB-2jfqA:
undetectable		 5eeyA-2jfqA:
16.22
5eeyB-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eeyA-2vvtA:
undetectable
5eeyB-2vvtA:
undetectable		 5eeyA-2vvtA:
12.76
5eeyB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5eeyA-2w4iA:
undetectable
5eeyB-2w4iA:
undetectable		 5eeyA-2w4iA:
14.79
5eeyB-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5eeyA-3outA:
undetectable
5eeyB-3outA:
undetectable		 5eeyA-3outA:
12.83
5eeyB-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5eeyA-5hj7A:
undetectable
5eeyB-5hj7A:
undetectable		 5eeyA-5hj7A:
16.27
5eeyB-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eeyA-5ijwA:
undetectable
5eeyB-5ijwA:
undetectable		 5eeyA-5ijwA:
14.49
5eeyB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5eeyA-5w16A:
undetectable
5eeyB-5w16A:
undetectable		 5eeyA-5w16A:
undetectable
5eeyB-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5eezA-1zuwA:
undetectable
5eezB-1zuwA:
undetectable		 5eezA-1zuwA:
13.97
5eezB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5eezA-2dwuA:
undetectable
5eezB-2dwuA:
undetectable		 5eezA-2dwuA:
16.50
5eezB-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5eezA-2gzmA:
undetectable
5eezB-2gzmA:
undetectable		 5eezA-2gzmA:
13.75
5eezB-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5eezA-2jfqA:
undetectable
5eezB-2jfqA:
undetectable		 5eezA-2jfqA:
16.22
5eezB-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5eezA-2vvtA:
undetectable
5eezB-2vvtA:
undetectable		 5eezA-2vvtA:
12.76
5eezB-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5eezA-2w4iA:
undetectable
5eezB-2w4iA:
undetectable		 5eezA-2w4iA:
14.79
5eezB-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5eezA-3outA:
undetectable
5eezB-3outA:
undetectable		 5eezA-3outA:
12.83
5eezB-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5eezA-5hj7A:
undetectable
5eezB-5hj7A:
undetectable		 5eezA-5hj7A:
16.27
5eezB-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eezA-5ijwA:
undetectable
5eezB-5ijwA:
undetectable		 5eezA-5ijwA:
14.49
5eezB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5eezA-5w16A:
undetectable
5eezB-5w16A:
undetectable		 5eezA-5w16A:
undetectable
5eezB-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5ef0A-1zuwA:
undetectable
5ef0B-1zuwA:
undetectable		 5ef0A-1zuwA:
13.97
5ef0B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5ef0A-2dwuA:
undetectable
5ef0B-2dwuA:
undetectable		 5ef0A-2dwuA:
16.50
5ef0B-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.10A 5ef0A-2gzmA:
undetectable
5ef0B-2gzmA:
undetectable		 5ef0A-2gzmA:
13.75
5ef0B-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5ef0A-2jfqA:
undetectable
5ef0B-2jfqA:
undetectable		 5ef0A-2jfqA:
16.22
5ef0B-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef0A-2vvtA:
undetectable
5ef0B-2vvtA:
undetectable		 5ef0A-2vvtA:
12.76
5ef0B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5ef0A-2w4iA:
undetectable
5ef0B-2w4iA:
undetectable		 5ef0A-2w4iA:
14.79
5ef0B-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5ef0A-3outA:
undetectable
5ef0B-3outA:
undetectable		 5ef0A-3outA:
12.83
5ef0B-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5ef0A-5hj7A:
undetectable
5ef0B-5hj7A:
undetectable		 5ef0A-5hj7A:
16.27
5ef0B-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef0A-5ijwA:
undetectable
5ef0B-5ijwA:
undetectable		 5ef0A-5ijwA:
14.49
5ef0B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5ef0A-5w16A:
undetectable
5ef0B-5w16A:
undetectable		 5ef0A-5w16A:
undetectable
5ef0B-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5ef1A-1zuwA:
undetectable
5ef1B-1zuwA:
undetectable		 5ef1A-1zuwA:
13.97
5ef1B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5ef1A-2dwuA:
undetectable
5ef1B-2dwuA:
undetectable		 5ef1A-2dwuA:
16.50
5ef1B-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.09A 5ef1A-2gzmA:
undetectable
5ef1B-2gzmA:
undetectable		 5ef1A-2gzmA:
13.75
5ef1B-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5ef1A-2jfqA:
undetectable
5ef1B-2jfqA:
undetectable		 5ef1A-2jfqA:
16.22
5ef1B-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef1A-2vvtA:
undetectable
5ef1B-2vvtA:
undetectable		 5ef1A-2vvtA:
12.76
5ef1B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5ef1A-2w4iA:
undetectable
5ef1B-2w4iA:
undetectable		 5ef1A-2w4iA:
14.79
5ef1B-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5ef1A-3outA:
undetectable
5ef1B-3outA:
undetectable		 5ef1A-3outA:
12.83
5ef1B-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5ef1A-5hj7A:
undetectable
5ef1B-5hj7A:
undetectable		 5ef1A-5hj7A:
16.27
5ef1B-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef1A-5ijwA:
undetectable
5ef1B-5ijwA:
undetectable		 5ef1A-5ijwA:
14.49
5ef1B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5ef1A-5w16A:
undetectable
5ef1B-5w16A:
undetectable		 5ef1A-5w16A:
undetectable
5ef1B-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.09A 5ef2A-1zuwA:
undetectable
5ef2B-1zuwA:
undetectable		 5ef2A-1zuwA:
13.97
5ef2B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5ef2A-2dwuA:
undetectable
5ef2B-2dwuA:
undetectable		 5ef2A-2dwuA:
16.50
5ef2B-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.09A 5ef2A-2gzmA:
undetectable
5ef2B-2gzmA:
undetectable		 5ef2A-2gzmA:
13.75
5ef2B-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5ef2A-2jfqA:
undetectable
5ef2B-2jfqA:
undetectable		 5ef2A-2jfqA:
16.22
5ef2B-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef2A-2vvtA:
undetectable
5ef2B-2vvtA:
undetectable		 5ef2A-2vvtA:
12.76
5ef2B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.10A 5ef2A-2w4iA:
undetectable
5ef2B-2w4iA:
undetectable		 5ef2A-2w4iA:
14.79
5ef2B-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5ef2A-3outA:
undetectable
5ef2B-3outA:
undetectable		 5ef2A-3outA:
12.83
5ef2B-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5ef2A-5hj7A:
undetectable
5ef2B-5hj7A:
undetectable		 5ef2A-5hj7A:
16.27
5ef2B-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef2A-5ijwA:
undetectable
5ef2B-5ijwA:
undetectable		 5ef2A-5ijwA:
14.49
5ef2B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5ef2A-5w16A:
undetectable
5ef2B-5w16A:
undetectable		 5ef2A-5w16A:
undetectable
5ef2B-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
 1.10A 5ef3A-1zuwA:
undetectable
5ef3B-1zuwA:
undetectable		 5ef3A-1zuwA:
13.97
5ef3B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 187
THR A 189
HIS A 190
THR A 124
THR A 121
 None
DGL  A 278 (-3.0A)
DGL  A 278 ( 4.5A)
None
DGL  A 278 (-3.6A)
 1.09A 5ef3A-2dwuA:
undetectable
5ef3B-2dwuA:
undetectable		 5ef3A-2dwuA:
16.50
5ef3B-2dwuA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2gzm GLUTAMATE RACEMASE
(Bacillus
anthracis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A 501 (-3.0A)
DGL  A 501 (-4.4A)
None
DGL  A 501 (-3.6A)
 1.09A 5ef3A-2gzmA:
undetectable
5ef3B-2gzmA:
undetectable		 5ef3A-2gzmA:
13.75
5ef3B-2gzmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 10 GLY A 183
THR A 185
HIS A 186
THR A 119
THR A 116
 None
DGL  A1267 (-2.8A)
DGL  A1267 (-4.4A)
None
DGL  A1267 (-3.7A)
 1.09A 5ef3A-2jfqA:
undetectable
5ef3B-2jfqA:
undetectable		 5ef3A-2jfqA:
16.22
5ef3B-2jfqA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
 None
DGL  A1270 (-3.0A)
I24  A1269 (-3.9A)
None
DGL  A1270 (-3.6A)
 1.10A 5ef3A-2vvtA:
undetectable
5ef3B-2vvtA:
undetectable		 5ef3A-2vvtA:
12.76
5ef3B-2vvtA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 10 GLY A 180
THR A 182
HIS A 183
THR A 119
THR A 116
 None
DGL  A1256 (-3.1A)
DGL  A1256 ( 4.5A)
None
DGL  A1256 (-3.5A)
 1.11A 5ef3A-2w4iA:
undetectable
5ef3B-2w4iA:
undetectable		 5ef3A-2w4iA:
14.79
5ef3B-2w4iA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 10 GLY A 182
THR A 184
HIS A 185
THR A 119
THR A 116
 None
DGL  A 266 (-3.3A)
DGL  A 266 ( 4.8A)
None
DGL  A 266 ( 3.8A)
 1.08A 5ef3A-3outA:
undetectable
5ef3B-3outA:
undetectable		 5ef3A-3outA:
12.83
5ef3B-3outA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 122
THR A 119
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 4.4A)
None
DGL  A 301 (-3.6A)
 1.13A 5ef3A-5hj7A:
undetectable
5ef3B-5hj7A:
undetectable		 5ef3A-5hj7A:
16.27
5ef3B-5hj7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef3A-5ijwA:
undetectable
5ef3B-5ijwA:
undetectable		 5ef3A-5ijwA:
14.49
5ef3B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		5 / 10 GLY A 175
THR A 177
HIS A 178
THR A 119
THR A 116
 None
DGL  A 301 (-2.9A)
DGL  A 301 ( 3.9A)
None
DGL  A 301 (-3.5A)
 1.15A 5ef3A-5w16A:
undetectable
5ef3B-5w16A:
undetectable		 5ef3A-5w16A:
undetectable
5ef3B-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 2w4i GLUTAMATE RACEMASE
(Helicobacter
pylori) 		5 / 12 ILE A 214
LEU A  66
ASP A   7
GLY A  12
ALA A  73
 None
None
DGL  A1256 (-3.5A)
None
None
 1.07A 5j7wD-2w4iA:
undetectable		 5j7wD-2w4iA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		4 / 7 TYR A 130
THR A 124
THR A  79
LEU A 184
 None
None
DGL  A 278 (-3.7A)
None
 1.11A 5jq7B-2dwuA:
undetectable		 5jq7B-2dwuA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		4 / 7 TYR A 125
THR A 119
THR A  74
LEU A 112
 None
None
DGL  A1267 (-3.7A)
None
 1.03A 5jq7B-2jfqA:
undetectable		 5jq7B-2jfqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 2vvt GLUTAMATE RACEMASE
(Enterococcus
faecalis) 		4 / 7 TYR A 127
THR A 121
THR A  76
LEU A 181
 None
None
DGL  A1270 (-3.8A)
None
 1.13A 5jq7B-2vvtA:
undetectable		 5jq7B-2vvtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 8 THR A 196
SER A 107
MET A  14
ALA A  90
 DGL  A 301 (-3.2A)
None
None
None
 1.05A 5l5fY-5xniA:
undetectable
5l5fZ-5xniA:
undetectable		 5l5fY-5xniA:
14.76
5l5fZ-5xniA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.48A 5l66V-1zuwA:
undetectable
5l66b-1zuwA:
undetectable		 5l66V-1zuwA:
21.83
5l66b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.40A 5l66V-2jfqA:
undetectable
5l66b-2jfqA:
undetectable		 5l66V-2jfqA:
19.42
5l66b-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis) 		5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
 None
DGL  A1301 (-3.7A)
None
None
None
 1.47A 5l66H-1zuwA:
undetectable
5l66N-1zuwA:
undetectable		 5l66H-1zuwA:
21.83
5l66N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2jfq GLUTAMATE RACEMASE
(Staphylococcus
aureus) 		5 / 11 SER A 207
THR A  74
THR A  76
GLY A  14
THR A  16
 None
DGL  A1267 (-3.7A)
None
None
None
 1.39A 5l66H-2jfqA:
undetectable
5l66N-2jfqA:
undetectable		 5l66H-2jfqA:
19.42
5l66N-2jfqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5hj7 GLUTAMATE RACEMASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 250
HIS A 187
SER A  77
ARG A 154
PRO A  46
 None
DGL  A 301 ( 4.4A)
DGL  A 301 (-2.7A)
None
None
 1.20A 5nd2B-5hj7A:
2.2		 5nd2B-5hj7A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		5 / 7 PHE A 137
HIS A  91
ILE A  85
SER A 128
THR A 131
 None
None
None
DGL  A 301 ( 4.0A)
None
 1.15A 5vkqA-5xniA:
undetectable
5vkqD-5xniA:
undetectable		 5vkqA-5xniA:
undetectable
5vkqD-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 7 SER A 128
THR A 131
HIS A  91
ILE A  85
 DGL  A 301 ( 4.0A)
None
None
None
 1.15A 5vkqA-5xniA:
undetectable
5vkqB-5xniA:
undetectable		 5vkqA-5xniA:
undetectable
5vkqB-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 7 SER A 128
THR A 131
PHE A 137
HIS A  91
 DGL  A 301 ( 4.0A)
None
None
None
 0.98A 5vkqA-5xniA:
undetectable
5vkqB-5xniA:
undetectable		 5vkqA-5xniA:
undetectable
5vkqB-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 8 SER A 128
THR A 131
HIS A  91
ILE A  85
 DGL  A 301 ( 4.0A)
None
None
None
 1.13A 5vkqB-5xniA:
undetectable
5vkqC-5xniA:
undetectable		 5vkqB-5xniA:
undetectable
5vkqC-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 8 SER A 128
THR A 131
PHE A 137
HIS A  91
 DGL  A 301 ( 4.0A)
None
None
None
 0.97A 5vkqB-5xniA:
undetectable
5vkqC-5xniA:
undetectable		 5vkqB-5xniA:
undetectable
5vkqC-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 7 SER A 128
THR A 131
HIS A  91
ILE A  85
 DGL  A 301 ( 4.0A)
None
None
None
 1.13A 5vkqC-5xniA:
undetectable
5vkqD-5xniA:
undetectable		 5vkqC-5xniA:
undetectable
5vkqD-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5xni MCYF
(Microcystis
aeruginosa) 		4 / 7 SER A 128
THR A 131
PHE A 137
HIS A  91
 DGL  A 301 ( 4.0A)
None
None
None
 0.97A 5vkqC-5xniA:
undetectable
5vkqD-5xniA:
undetectable		 5vkqC-5xniA:
undetectable
5vkqD-5xniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3out GLUTAMATE RACEMASE
(Francisella
tularensis) 		5 / 12 GLY A  13
GLY A  36
VAL A  20
GLY A  16
GLY A  15
 DGL  A 266 (-4.6A)
None
None
None
None
 0.88A 5zhmB-3outA:
4.3		 5zhmB-3outA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		3 / 3 VAL A  42
TYR A  44
GLU A 145
 NO3  A 302 (-4.9A)
DGL  A 301 (-4.9A)
NO3  A 302 ( 4.0A)
 0.87A 5zmqD-5w16A:
undetectable
5zmqE-5w16A:
undetectable		 5zmqD-5w16A:
undetectable
5zmqE-5w16A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 2dwu GLUTAMATE RACEMASE
(Bacillus
anthracis) 		6 / 12 ILE A 251
SER A 247
GLY A 243
THR A 241
GLY A  39
ASP A  14
 None
None
None
None
None
DGL  A 278 (-3.6A)
 1.47A 6b6fA-2dwuA:
undetectable		 6b6fA-2dwuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3ijl MUCONATE
CYCLOISOMERASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A  94
ASP A 276
GLU A 277
ALA A  64
 DGL  A 385 (-4.5A)
MG  A 386 (-3.1A)
MG  A 386 ( 3.9A)
None
 1.19A 6djzB-3ijlA:
undetectable		 6djzB-3ijlA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5w16 GLUTAMATE RACEMASE
(Thermus
thermophilus) 		4 / 5 GLY A 115
THR A 116
SER A  79
SER A  80
 None
DGL  A 301 (-3.5A)
None
None
 1.15A 6jmjA-5w16A:
2.9		 6jmjA-5w16A:
undetectable