SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DD9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC552_1 (GLUTAMATE DEHYDROGENASE)	5kym	1-ACYL-SN-GLYCEROL-3 -PHOSPHATE ACYLTRANSFERASE (Thermotoga maritima)	3 / 3	TYR A 117 TYR A 44 GLY A 25	DD9 A 304 (-3.4A) None DD9 A 304 ( 3.9A)	0.75A	3eteB-5kymA: undetectable 3eteD-5kymA: undetectable 3eteF-5kymA: undetectable	3eteB-5kymA: 20.16 3eteD-5kymA: 20.16 3eteF-5kymA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_2 (GENOME POLYPROTEIN)	5kym	1-ACYL-SN-GLYCEROL-3 -PHOSPHATE ACYLTRANSFERASE (Thermotoga maritima)	3 / 3	PHE A 13 TYR A 20 LEU A 8	None DD9 A 304 ( 4.7A) None	0.71A	3keeB-5kymA: undetectable	3keeB-5kymA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_B_SUEB1201_2 (NS3 PROTEASE, NS4A PROTEIN)	5kym	1-ACYL-SN-GLYCEROL-3 -PHOSPHATE ACYLTRANSFERASE (Thermotoga maritima)	3 / 3	PHE A 13 TYR A 20 LEU A 8	None DD9 A 304 ( 4.7A) None	0.67A	3sueB-5kymA: undetectable	3sueB-5kymA: 21.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ETE_C_H3PC552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","5kym","1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE","Thermotoga maritima",3,"TYR A 117;TYR A  44;GLY A  25","DD9 A 304 (-3.4A);None;DD9 A 304 ( 3.9A)","0.75A","3eteB-5kymA:undetectable;3eteD-5kymA:undetectable;3eteF-5kymA:undetectable",null],["3KEE_B_30BB500_2","GENOME POLYPROTEIN","5kym","1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE","Thermotoga maritima",3,"PHE A  13;TYR A  20;LEU A   8","None;DD9 A 304 ( 4.7A);None","0.71A","3keeB-5kymA:undetectable","3eteB-5kymA:20.16;3eteD-5kymA:20.16;3eteF-5kymA:20.16"],["3SUE_B_SUEB1201_2","NS3 PROTEASE, NS4A PROTEIN","5kym","1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE","Thermotoga maritima",3,"PHE A  13;TYR A  20;LEU A   8","None;DD9 A 304 ( 4.7A);None","0.67A","3sueB-5kymA:undetectable","3keeB-5kymA:20.24"]]