SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DCT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 2ktq PROTEIN (LARGE
FRAGMENT OF DNA
POLYMERASE I)
(Thermus
aquaticus) 		4 / 5 TYR A 671
LEU A 622
THR A 571
ARG A 728
 DCT  A 113 (-4.7A)
None
None
None
 1.31A 1i2wA-2ktqA:
undetectable		 1i2wA-2ktqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 2ktq PROTEIN (LARGE
FRAGMENT OF DNA
POLYMERASE I)
(Thermus
aquaticus) 		4 / 7 ASP A 610
ASP A 785
GLN A 582
GLU A 786
 MG  A 901 (-4.3A)
DCT  A 113 ( 2.4A)
None
None
 1.26A 3s3oA-2ktqA:
undetectable		 3s3oA-2ktqA:
21.61