SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DBI'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		4 / 8 CYH A  59
TYR A 117
LEU A  57
MET A 130
 None
DBI  A 139 (-2.7A)
None
None
 1.23A 1uw6A-1id8A:
undetectable
1uw6B-1id8A:
undetectable		 1uw6A-1id8A:
21.53
1uw6B-1id8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		4 / 8 CYH A  59
TYR A 117
LEU A  57
MET A 130
 None
DBI  A 139 (-2.7A)
None
None
 1.25A 1uw6D-1id8A:
undetectable
1uw6E-1id8A:
undetectable		 1uw6D-1id8A:
21.53
1uw6E-1id8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		4 / 8 CYH A  59
TYR A 117
LEU A  57
MET A 130
 None
DBI  A 139 (-2.7A)
None
None
 1.22A 1uw6G-1id8A:
undetectable
1uw6H-1id8A:
undetectable		 1uw6G-1id8A:
21.53
1uw6H-1id8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		4 / 8 CYH A  59
TYR A 117
LEU A  57
MET A 130
 None
DBI  A 139 (-2.7A)
None
None
 1.21A 1uw6P-1id8A:
undetectable
1uw6Q-1id8A:
undetectable		 1uw6P-1id8A:
21.53
1uw6Q-1id8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		4 / 8 GLY A  92
ASP A 114
ARG A  75
TRP A 101
 DBI  A 139 ( 3.5A)
None
None
None
 0.83A 5gqbA-1id8A:
undetectable		 5gqbA-1id8A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1id8 METHYLASPARTATE
MUTASE S CHAIN
(Clostridium
tetanomorphum) 		5 / 12 LEU A  23
GLY A  91
GLY A  92
VAL A 116
LEU A  57
 DBI  A 139 (-4.3A)
DBI  A 139 (-2.7A)
DBI  A 139 ( 3.5A)
None
None
 1.20A 5uc1A-1id8A:
undetectable		 5uc1A-1id8A:
14.60