SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'DAL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 8 GLY A 293
SER A 267
PHE A  51
HIS A  55
 DAL  A2472 ( 4.5A)
None
ALA  A2473 ( 4.6A)
None
 0.88A 1ax9A-3q4dA:
2.2		 1ax9A-3q4dA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 12 ILE A 221
LEU A 198
PHE A 245
ILE A 216
THR A 488
 None
DAL  A 701 ( 4.1A)
None
None
None
 1.07A 1cd2A-3dhvA:
undetectable		 1cd2A-3dhvA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2yzm D-ALANINE--D-ALANINE
LIGASE
(Thermus
thermophilus) 		3 / 3 VAL A  36
ALA A   7
HIS A  82
 None
None
DAL  A 401 (-4.5A)
 0.73A 1q23H-2yzmA:
undetectable		 1q23H-2yzmA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Desulfovibrio
alaskensis) 		5 / 12 PRO A 221
GLY A 157
ILE A 160
VAL A 154
ASN A 219
 CL  A 401 (-3.8A)
CL  A 401 ( 3.8A)
DAL  A 402 (-4.9A)
None
DAL  A 403 (-2.9A)
 1.14A 1sg9A-4nguA:
undetectable		 1sg9A-4nguA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Desulfovibrio
alaskensis) 		5 / 12 GLY A 216
TYR A 190
ILE A 200
ARG A 180
VAL A 205
 None
None
None
DAL  A 403 (-3.0A)
None
 1.35A 1tmxB-4nguA:
undetectable		 1tmxB-4nguA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 2yzm D-ALANINE--D-ALANINE
LIGASE
(Thermus
thermophilus) 		4 / 4 GLY A   8
SER A  17
ILE A 286
HIS A  82
 None
None
None
DAL  A 401 (-4.5A)
 1.03A 1yajJ-2yzmA:
2.1		 1yajJ-2yzmA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 4 GLY A 293
SER A 267
ILE A  54
HIS A  55
 DAL  A2472 ( 4.5A)
None
None
None
 1.01A 1yajJ-3q4dA:
undetectable		 1yajJ-3q4dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Chromohalobacter
salexigens) 		5 / 12 ASN A 216
GLN A 239
SER A 182
LEU A 186
THR A 202
 DAL  A 403 (-3.0A)
None
None
None
None
 1.45A 2aa5A-4n8gA:
undetectable		 2aa5A-4n8gA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Chromohalobacter
salexigens) 		5 / 12 ASN A 216
GLN A 239
SER A 182
LEU A 186
THR A 202
 DAL  A 403 (-3.0A)
None
None
None
None
 1.45A 2aa5B-4n8gA:
undetectable		 2aa5B-4n8gA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		3 / 3 LEU A 198
MET A 201
MET A  64
 DAL  A 701 ( 4.1A)
None
None
 0.99A 2vavF-3dhvA:
undetectable		 2vavF-3dhvA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		4 / 7 PHE A 180
LEU A 198
ALA A 302
ALA A 176
 None
DAL  A 701 ( 4.1A)
None
None
 0.84A 2vcvG-3dhvA:
1.8		 2vcvG-3dhvA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		4 / 7 LEU A 198
GLY A 270
GLY A 295
THR A 297
 DAL  A 701 ( 4.1A)
DAL  A 701 ( 3.1A)
AMP  A 711 ( 4.7A)
AMP  A 711 (-3.9A)
 0.62A 2wd9A-3dhvA:
37.8		 2wd9A-3dhvA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		4 / 8 LEU A 198
GLY A 270
GLY A 295
THR A 297
 DAL  A 701 ( 4.1A)
DAL  A 701 ( 3.1A)
AMP  A 711 ( 4.7A)
AMP  A 711 (-3.9A)
 0.61A 2wd9B-3dhvA:
37.2		 2wd9B-3dhvA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 10 THR A 152
LEU A 198
GLY A 270
GLY A 295
THR A 297
 None
DAL  A 701 ( 4.1A)
DAL  A 701 ( 3.1A)
AMP  A 711 ( 4.7A)
AMP  A 711 (-3.9A)
 0.63A 2wd9C-3dhvA:
37.2		 2wd9C-3dhvA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Desulfovibrio
alaskensis) 		4 / 8 GLN A 246
GLN A 242
ILE A 160
SER A  99
 DAL  A 402 (-4.0A)
None
DAL  A 402 (-4.9A)
DAL  A 402 (-4.5A)
 1.10A 2xz5B-4nguA:
undetectable
2xz5E-4nguA:
undetectable		 2xz5B-4nguA:
20.44
2xz5E-4nguA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Desulfovibrio
alaskensis) 		3 / 3 VAL A 154
ASN A  40
TRP A 202
 None
DAL  A 403 (-4.2A)
DAL  A 403 (-4.1A)
 1.10A 2y00B-4nguA:
undetectable		 2y00B-4nguA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 9 THR A  53
ILE A  54
GLY A  24
PHE A  19
ILE A  21
 None
None
None
DAL  A2472 (-4.8A)
ALA  A2473 ( 4.8A)
 1.41A 2y7wA-3q4dA:
undetectable		 2y7wA-3q4dA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Chromohalobacter
salexigens) 		4 / 8 ILE A 106
SER A 241
ASP A 180
SER A  95
 None
DAL  A 402 (-2.8A)
None
DAL  A 403 ( 4.7A)
 1.03A 2zw9B-4n8gA:
undetectable		 2zw9B-4n8gA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 127
ASP A 196
SER A  19
PRO A  21
ILE A  76
 DAL  A 302 (-3.5A)
None
None
None
DAL  A 302 (-4.9A)
 1.19A 3clbB-4f3sA:
undetectable		 3clbB-4f3sA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		4 / 5 PRO A  80
THR A 488
GLY A 491
LYS A 492
 None
None
None
DAL  A 701 ( 3.2A)
 0.94A 3elzB-3dhvA:
undetectable		 3elzB-3dhvA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A  78
ASP A 196
THR A  79
ILE A  86
ILE A  76
 None
None
None
None
DAL  A 302 (-4.9A)
 0.99A 3kpdC-4f3sA:
undetectable		 3kpdC-4f3sA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Chromohalobacter
salexigens) 		5 / 12 GLY A 311
LEU A 156
THR A 234
ILE A 165
PHE A 307
 None
DAL  A 402 ( 4.7A)
None
None
None
 1.30A 3mneA-4n8gA:
undetectable		 3mneA-4n8gA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4n8g TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Chromohalobacter
salexigens) 		5 / 12 GLY A 311
LEU A 156
THR A 234
ILE A 165
PHE A 307
 None
DAL  A 402 ( 4.7A)
None
None
None
 1.30A 3mnpA-4n8gA:
undetectable		 3mnpA-4n8gA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3tcs RACEMASE, PUTATIVE
(Roseobacter
denitrificans) 		5 / 12 GLN A 256
GLN A 236
ASP A 183
SER A 118
MET A 119
 None
None
MG  A 368 ( 2.7A)
None
DAL  A 370 (-3.5A)
 1.27A 3t7sA-3tcsA:
undetectable		 3t7sA-3tcsA:
20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 7 PHE A 196
ASP A 197
GLY A 270
THR A 297
LYS A 492
 DAL  A 701 (-4.7A)
DAL  A 701 ( 2.7A)
DAL  A 701 ( 3.1A)
AMP  A 711 (-3.9A)
DAL  A 701 ( 3.2A)
 0.85A 3vnsA-3dhvA:
45.5		 3vnsA-3dhvA:
31.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 5 PHE A  51
PHE A  19
ILE A  21
THR A 135
 ALA  A2473 ( 4.6A)
DAL  A2472 (-4.8A)
ALA  A2473 ( 4.8A)
DAL  A2472 (-3.6A)
 0.68A 4ejjC-3q4dA:
undetectable		 4ejjC-3q4dA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3tcs RACEMASE, PUTATIVE
(Roseobacter
denitrificans) 		4 / 5 HIS A 207
VAL A 231
GLU A 209
LYS A 145
 None
None
MG  A 368 ( 2.8A)
DAL  A 370 (-2.9A)
 1.34A 4p6vB-3tcsA:
undetectable
4p6vE-3tcsA:
undetectable		 4p6vB-3tcsA:
23.28
4p6vE-3tcsA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1xof BBAHETT1
() 		4 / 6 GLU A 113
PHE B 212
ARG B 217
TYR A 101
 DAL  A 109 ( 4.1A)
None
None
DBZ  B 220 ( 3.6A)
 1.26A 4uciA-1xofA:
undetectable		 4uciA-1xofA:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1xof BBAHETT1
() 		4 / 7 GLU A 113
PHE B 212
ARG B 217
TYR A 101
 DAL  A 109 ( 4.1A)
None
None
DBZ  B 220 ( 3.6A)
 1.25A 4uciB-1xofA:
undetectable		 4uciB-1xofA:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3tcs RACEMASE, PUTATIVE
(Roseobacter
denitrificans) 		4 / 7 GLU A 209
PHE A 205
LYS A 145
HIS A 207
 MG  A 368 ( 2.8A)
None
DAL  A 370 (-2.9A)
None
 1.28A 4uciB-3tcsA:
undetectable		 4uciB-3tcsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 7 PHE A 196
ASP A 197
GLY A 270
THR A 297
LYS A 492
 DAL  A 701 (-4.7A)
DAL  A 701 ( 2.7A)
DAL  A 701 ( 3.1A)
AMP  A 711 (-3.9A)
DAL  A 701 ( 3.2A)
 0.65A 4zxiA-3dhvA:
43.9		 4zxiA-3dhvA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5nri D-ALANINE--D-ALANINE
LIGASE
(Burkholderia
pseudomallei) 		5 / 6 TYR A 215
ARG A 260
GLY A 281
SER A 286
LEU A 287
 None
DAL  A 402 (-4.1A)
DAL  A 402 (-4.3A)
DAL  A 402 (-3.6A)
DAL  A 402 (-3.8A)
 0.72A 5bphA-5nriA:
39.8		 5bphA-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 5nri D-ALANINE--D-ALANINE
LIGASE
(Burkholderia
pseudomallei) 		4 / 7 TYR A 215
LYS A 220
TYR A 221
ARG A 260
 None
AMP  A 401 ( 4.2A)
None
DAL  A 402 (-4.1A)
 0.96A 5bphB-5nriA:
39.9		 5bphB-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5nri D-ALANINE--D-ALANINE
LIGASE
(Burkholderia
pseudomallei) 		4 / 4 TYR A 215
GLY A 281
SER A 286
LEU A 287
 None
DAL  A 402 (-4.3A)
DAL  A 402 (-3.6A)
DAL  A 402 (-3.8A)
 0.76A 5bphC-5nriA:
39.9		 5bphC-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2yzm D-ALANINE--D-ALANINE
LIGASE
(Thermus
thermophilus) 		5 / 12 ILE A 286
HIS A  82
GLY A  86
GLU A 199
ALA A 109
 None
DAL  A 401 (-4.5A)
None
None
None
 1.21A 5ih0A-2yzmA:
undetectable		 5ih0A-2yzmA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.37A 5iqbA-3q4dA:
undetectable		 5iqbA-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.48A 5iqbD-3q4dA:
undetectable		 5iqbD-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 11 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.37A 5iqeA-3q4dA:
0.0		 5iqeA-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 2yzm D-ALANINE--D-ALANINE
LIGASE
(Thermus
thermophilus) 		4 / 5 LYS A 153
GLU A 282
GLY A 158
SER A 160
 None
None
DAL  A 401 ( 4.2A)
None
 0.94A 5jhdJ-2yzmA:
undetectable		 5jhdJ-2yzmA:
23.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 7 PHE A 196
ASP A 197
GLY A 270
GLY A 295
LYS A 492
 DAL  A 701 (-4.7A)
DAL  A 701 ( 2.7A)
DAL  A 701 ( 3.1A)
AMP  A 711 ( 4.7A)
DAL  A 701 ( 3.2A)
 0.77A 5n9xA-3dhvA:
46.4		 5n9xA-3dhvA:
31.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		3 / 3 ASP A 241
ASN A 263
ASP A 318
 MG  A1602 ( 3.0A)
MG  A1602 ( 4.7A)
DAL  A2472 ( 2.4A)
 0.83A 5vopB-3q4dA:
6.4		 5vopB-3q4dA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE
(Bacillus
cereus) 		5 / 12 GLY A 270
THR A 242
PRO A 243
THR A 304
LEU A 392
 DAL  A 701 ( 3.1A)
None
None
None
None
 1.17A 5ybbA-3dhvA:
undetectable		 5ybbA-3dhvA:
23.77