SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'D3M'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 3gb4 DDMC
(Stenotrophomonas
maltophilia) 		4 / 7 ASP A 294
HIS A 165
LEU A 155
ASN A 230
 CO  A 502 (-1.9A)
CO  A 502 (-3.3A)
None
D3M  A 601 (-2.8A)
 1.00A 3avpA-3gb4A:
undetectable		 3avpA-3gb4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3gb4 DDMC
(Stenotrophomonas
maltophilia) 		4 / 7 LEU A 158
ILE A 331
TRP A 222
MET A 228
 D3M  A 601 ( 4.0A)
None
None
None
 1.43A 5ljcA-3gb4A:
1.9		 5ljcA-3gb4A:
17.51