SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CZA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
 None
None
CZA  A1002 (-4.1A)
None
None
 1.33A 3ko0A-5mpmA:
undetectable
3ko0B-5mpmA:
undetectable
3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
1.0		 3ko0A-5mpmA:
24.47
3ko0B-5mpmA:
24.47
3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
 None
CZA  A1002 (-4.1A)
None
None
None
 1.38A 3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
0.9
3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable		 3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
 None
None
CZA  A1002 (-4.1A)
None
None
 1.34A 3ko0C-5mpmA:
undetectable
3ko0D-5mpmA:
1.0
3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable		 3ko0C-5mpmA:
24.47
3ko0D-5mpmA:
24.47
3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
 None
CZA  A1002 (-4.1A)
None
None
None
 1.33A 3ko0E-5mpmA:
undetectable
3ko0F-5mpmA:
undetectable
3ko0G-5mpmA:
undetectable
3ko0H-5mpmA:
undetectable		 3ko0E-5mpmA:
24.47
3ko0F-5mpmA:
24.47
3ko0G-5mpmA:
24.47
3ko0H-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 12 GLU A 309
LEU A  65
ILE A  94
ASP A 799
SER A 766
 None
CZA  A1002 (-4.1A)
None
None
None
 1.34A 3ko0G-5mpmA:
undetectable
3ko0H-5mpmA:
undetectable
3ko0I-5mpmA:
undetectable
3ko0J-5mpmA:
undetectable		 3ko0G-5mpmA:
24.47
3ko0H-5mpmA:
24.47
3ko0I-5mpmA:
24.47
3ko0J-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 ASP A 799
SER A 766
GLU A 309
LEU A  65
ILE A  94
 None
None
None
CZA  A1002 (-4.1A)
None
 1.38A 3ko0K-5mpmA:
undetectable
3ko0L-5mpmA:
0.9
3ko0M-5mpmA:
undetectable
3ko0N-5mpmA:
undetectable		 3ko0K-5mpmA:
24.47
3ko0L-5mpmA:
24.47
3ko0M-5mpmA:
24.47
3ko0N-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 LEU A  65
ILE A  94
GLU A 309
ASP A 799
SER A 766
 CZA  A1002 (-4.1A)
None
None
None
None
 1.34A 3ko0O-5mpmA:
1.1
3ko0P-5mpmA:
undetectable
3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable		 3ko0O-5mpmA:
24.47
3ko0P-5mpmA:
24.47
3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 10 ASP A 799
SER A 766
LEU A  65
ILE A  94
GLU A 309
 None
None
CZA  A1002 (-4.1A)
None
None
 1.34A 3ko0O-5mpmA:
1.0
3ko0P-5mpmA:
undetectable
3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable		 3ko0O-5mpmA:
24.47
3ko0P-5mpmA:
24.47
3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2
(Sus
scrofa) 		5 / 11 ASP A 799
SER A 766
GLU A 309
LEU A  65
ILE A  94
 None
None
None
CZA  A1002 (-4.1A)
None
 1.33A 3ko0Q-5mpmA:
undetectable
3ko0R-5mpmA:
undetectable
3ko0S-5mpmA:
undetectable
3ko0T-5mpmA:
undetectable		 3ko0Q-5mpmA:
24.47
3ko0R-5mpmA:
24.47
3ko0S-5mpmA:
24.47
3ko0T-5mpmA:
24.47