SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CYZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 12 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.35A 1lbcA-3h6tA:
44.1
1lbcC-3h6tA:
43.4		 1lbcA-3h6tA:
100.00
1lbcC-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
 0.88A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-2.9A)
 0.96A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.72A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.96A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.93A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		9 / 9 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
ASP A 248
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
None
CYZ  A 265 ( 4.4A)
 0.46A 1lbcB-3h6tA:
43.6		 1lbcB-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
 0.85A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.70A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.30A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.19A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.94A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.64A 1lbcB-5weoA:
24.9		 1lbcB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 12 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.37A 1lbcA-3h6tA:
44.1
1lbcC-3h6tA:
43.4		 1lbcA-3h6tA:
100.00
1lbcC-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.66A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.20A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.16A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.65A 1lbcA-5weoA:
25.1
1lbcC-5weoA:
25.0		 1lbcA-5weoA:
34.03
1lbcC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.69A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.99A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.97A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.68A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.66A 3h6tB-5weoA:
25.2		 3h6tB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.67A 3h6tB-5weoA:
25.2		 3h6tB-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
 0.68A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.94A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.91A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.63A 3h6tA-5weoA:
25.6
3h6tC-5weoA:
25.4		 3h6tA-5weoA:
34.03
3h6tC-5weoA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 ILE A  92
PRO A 105
SER A 108
SER A 217
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
None
 0.64A 3ijxB-3h6tA:
42.8
3ijxD-3h6tA:
42.7		 3ijxB-3h6tA:
100.00
3ijxD-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
None
 0.55A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.90A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.94A 3ijxB-5weoA:
25.2
3ijxD-5weoA:
25.2		 3ijxB-5weoA:
66.93
3ijxD-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 5 LYS A 104
PRO A 105
LEU A 239
SER A 242
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
 0.59A 3ijxH-3h6tA:
42.6		 3ijxH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 5 LYS A 104
PRO A 105
SER A 108
LEU A 239
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
 0.83A 3ijxH-3h6tA:
42.6		 3ijxH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.92A 3ijxH-5weoA:
24.8		 3ijxH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		6 / 10 ILE A  92
PRO A 105
SER A 108
SER A 217
LYS A 218
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
None
None
 0.34A 3ik6B-3h6tA:
43.4
3ik6E-3h6tA:
43.5		 3ik6B-3h6tA:
100.00
3ik6E-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.60A 3ik6B-5weoA:
25.3
3ik6E-5weoA:
25.2		 3ik6B-5weoA:
66.93
3ik6E-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		6 / 10 ILE A  92
PRO A 105
SER A 108
SER A 217
LYS A 218
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
None
None
 0.61A 3ik6B-3h6tA:
43.4
3ik6E-3h6tA:
43.5		 3ik6B-3h6tA:
100.00
3ik6E-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.69A 3ik6B-5weoA:
25.3
3ik6E-5weoA:
25.2		 3ik6B-5weoA:
66.93
3ik6E-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 4 LYS A 493
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.92A 3ik6H-5weoA:
25.0		 3ik6H-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 12 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.57A 3iltB-3h6tA:
37.5
3iltE-3h6tA:
37.0		 3iltB-3h6tA:
100.00
3iltE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 12 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.96A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 12 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 1.02A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.97A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.81A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 10 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.57A 3iltB-3h6tA:
37.5
3iltE-3h6tA:
37.0		 3iltB-3h6tA:
100.00
3iltE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.05A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 1.05A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.98A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.78A 3iltB-5weoA:
21.4
3iltE-5weoA:
21.3		 3iltB-5weoA:
66.93
3iltE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		3 / 3 ILE A  92
SER A 108
SER A 217
 None
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
 0.42A 3iltH-3h6tA:
36.8		 3iltH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		3 / 3 ILE A 481
SER A 497
SER A 729
 None
CYZ  A1302 (-3.2A)
None
 0.39A 3iltH-5weoA:
21.0		 3iltH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 LYS A 104
PRO A 105
SER A 108
LEU A 239
SER A 242
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
 0.65A 3iluB-3h6tA:
43.8
3iluE-3h6tA:
43.3		 3iluB-3h6tA:
100.00
3iluE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 ILE A 481
PRO A 494
SER A 497
SER A 729
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
None
 0.59A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.89A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		6 / 11 ILE A  92
PRO A 105
SER A 108
SER A 217
LYS A 218
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
None
None
 0.57A 3iluB-3h6tA:
43.8
3iluE-3h6tA:
43.3		 3iluB-3h6tA:
100.00
3iluE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 11 ILE A 481
PRO A 494
SER A 497
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
GLU  A1301 ( 3.7A)
None
 0.68A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 11 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.93A 3iluB-5weoA:
25.3
3iluE-5weoA:
25.2		 3iluB-5weoA:
66.93
3iluE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 5 LYS A 104
PRO A 105
LEU A 239
SER A 242
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
 0.35A 3iluH-3h6tA:
43.1		 3iluH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 5 LYS A 104
PRO A 105
SER A 108
LEU A 239
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
 0.79A 3iluH-3h6tA:
43.1		 3iluH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 LYS A 493
PRO A 494
SER A 497
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
 0.97A 3iluH-5weoA:
25.0		 3iluH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		6 / 10 TYR A  35
PRO A 105
MET A 107
SER A 108
SER A 242
LEU A 247
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
 0.32A 3lsfB-3h6tA:
43.6
3lsfE-3h6tA:
43.0		 3lsfB-3h6tA:
100.00
3lsfE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 TYR A 424
PRO A 494
MET A 496
SER A 497
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.79A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 TYR A 424
PRO A 494
MET A 496
SER A 754
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
 0.93A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		6 / 10 PRO A 105
MET A 107
SER A 108
SER A 242
LEU A 247
LYS A 251
 CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.30A 3lsfB-3h6tA:
43.6
3lsfE-3h6tA:
43.0		 3lsfB-3h6tA:
100.00
3lsfE-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 497
LEU A 759
ASP A 760
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.77A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 497
LEU A 759
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 0.97A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 10 PRO A 494
MET A 496
SER A 754
LEU A 759
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.03A 3lsfB-5weoA:
25.2
3lsfE-5weoA:
25.1		 3lsfB-5weoA:
66.93
3lsfE-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 8 TYR A  35
MET A 107
SER A 108
ASP A 248
LYS A 251
 None
None
CYZ  A 265 (-2.8A)
None
CYZ  A 265 ( 4.4A)
 0.86A 3lsfH-3h6tA:
42.7		 3lsfH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		7 / 8 TYR A  35
PRO A 105
MET A 107
SER A 108
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.31A 3lsfH-3h6tA:
42.7		 3lsfH-3h6tA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 497
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-3.8A)
 0.68A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 497
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 (-2.9A)
 1.05A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 754
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
 0.83A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
MET A 496
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 1.02A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
CYZ  A1302 (-3.8A)
 0.83A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 497
LYS A 763
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
CYZ  A1302 (-2.9A)
 1.02A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 754
ASP A 760
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
 0.98A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 8 TYR A 424
PRO A 494
MET A 496
SER A 754
LYS A 763
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-2.9A)
 1.08A 3lsfH-5weoA:
24.6		 3lsfH-5weoA:
66.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 7 TYR A  35
MET A 107
LEU A 247
ASP A 248
LYS A 251
 None
None
CYZ  A 265 (-4.3A)
None
CYZ  A 265 ( 4.4A)
 0.96A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.56A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-2.9A)
 1.22A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 8 ILE A  92
PRO A 105
SER A 108
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
None
 0.38A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 8 ILE A  92
PRO A 105
SER A 217
GLY A 219
 None
CYZ  A 265 (-3.9A)
GOL  A 270 ( 3.0A)
None
 0.74A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 7 TYR A  35
MET A 107
ASP A 248
LYS A 251
 None
None
None
CYZ  A 265 ( 4.4A)
 1.08A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 7 TYR A  35
MET A 107
LEU A 247
LYS A 251
 None
None
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.49A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.50A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 7 TYR A 424
MET A 496
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-2.9A)
 1.20A 3lslA-5weoA:
25.4
3lslD-5weoA:
25.3		 3lslA-5weoA:
66.67
3lslD-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 8 ILE A  92
PRO A 105
SER A 108
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
None
 0.27A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 8 ILE A  92
PRO A 105
SER A 217
GLY A 219
 None
CYZ  A 265 (-3.9A)
GOL  A 270 ( 3.0A)
None
 0.68A 3lslA-3h6tA:
42.6
3lslD-3h6tA:
42.7		 3lslA-3h6tA:
99.61
3lslD-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 6 TYR A  35
MET A 107
ASP A 248
LYS A 251
 None
None
None
CYZ  A 265 ( 4.4A)
 1.03A 3lslG-3h6tA:
42.1		 3lslG-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		4 / 6 TYR A  35
MET A 107
LEU A 247
LYS A 251
 None
None
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.45A 3lslG-3h6tA:
42.1		 3lslG-3h6tA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		4 / 6 TYR A 424
MET A 496
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 (-3.8A)
 0.57A 3lslG-5weoA:
24.8		 3lslG-5weoA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 9 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.26A 3tkdA-3h6tA:
44.2		 3tkdA-3h6tA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
 0.67A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.91A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 5 ILE A  92
PRO A 105
SER A 217
LYS A 218
GLY A 219
 None
CYZ  A 265 (-3.9A)
GOL  A 270 ( 3.0A)
None
None
 0.18A 3tkdB-3h6tA:
42.7		 3tkdB-3h6tA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
None
GLU  A1301 ( 3.7A)
None
 0.61A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 5 ILE A  92
PRO A 105
SER A 217
LYS A 218
GLY A 219
 None
CYZ  A 265 (-3.9A)
GOL  A 270 ( 3.0A)
None
None
 0.17A 3tkdA-3h6tA:
44.2		 3tkdA-3h6tA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 5 ILE A 481
PRO A 494
SER A 729
LYS A 730
GLY A 731
 None
CYZ  A1302 (-4.5A)
None
GLU  A1301 ( 3.7A)
None
 0.59A 3tkdA-5weoA:
25.4		 3tkdA-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		8 / 9 LYS A 104
PRO A 105
MET A 107
SER A 108
LEU A 239
SER A 242
LEU A 247
LYS A 251
 None
CYZ  A 265 (-3.9A)
None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-2.9A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.36A 3tkdB-3h6tA:
42.7		 3tkdB-3h6tA:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
LEU A 751
SER A 754
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-2.9A)
 0.91A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
 0.73A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 LYS A 493
MET A 496
SER A 497
LEU A 751
LEU A 759
LYS A 763
 None
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-2.9A)
 0.90A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
LEU A 751
SER A 754
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
None
CYZ  A1302 ( 4.1A)
 0.90A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		5 / 9 LYS A 493
PRO A 494
MET A 496
SER A 497
LEU A 751
 None
CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
 0.66A 3tkdB-5weoA:
24.5		 3tkdB-5weoA:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 ILE A  92
PRO A 105
SER A 108
SER A 217
GLY A 219
 None
CYZ  A 265 (-3.9A)
CYZ  A 265 (-2.8A)
GOL  A 270 ( 3.0A)
None
 0.54A 5weoA-3h6tA:
8.2
5weoD-3h6tA:
7.2		 5weoA-3h6tA:
34.03
5weoD-3h6tA:
34.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.35A 6dlzA-5weoA:
56.2
6dlzD-5weoA:
56.0		 6dlzA-5weoA:
100.00
6dlzD-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.45A 6dlzB-5weoA:
55.9
6dlzC-5weoA:
56.1		 6dlzB-5weoA:
100.00
6dlzC-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.28A 6dlzB-5weoA:
55.9
6dlzC-5weoA:
56.1		 6dlzB-5weoA:
100.00
6dlzC-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.42A 6dlzA-5weoA:
56.2
6dlzD-5weoA:
56.0		 6dlzA-5weoA:
100.00
6dlzD-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.32A 6dm0A-5weoA:
45.4
6dm0D-5weoA:
56.0		 6dm0A-5weoA:
100.00
6dm0D-5weoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 MET A 107
SER A 108
LEU A 239
LEU A 247
LYS A 251
 None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.76A 6dm0B-3h6tA:
35.3
6dm0C-3h6tA:
21.2		 6dm0B-3h6tA:
15.44
6dm0C-3h6tA:
15.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 10 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.49A 6dm0B-5weoA:
55.9
6dm0C-5weoA:
45.3		 6dm0B-5weoA:
100.00
6dm0C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.32A 6dm0B-5weoA:
56.0
6dm0C-5weoA:
45.3		 6dm0B-5weoA:
100.00
6dm0C-5weoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 9 MET A 107
SER A 108
LEU A 239
LEU A 247
LYS A 251
 None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.77A 6dm0A-3h6tA:
21.2
6dm0D-3h6tA:
1.4		 6dm0A-3h6tA:
15.44
6dm0D-3h6tA:
15.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM0_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		6 / 9 MET A 496
SER A 497
LEU A 751
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.47A 6dm0A-5weoA:
45.4
6dm0D-5weoA:
56.0		 6dm0A-5weoA:
100.00
6dm0D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.34A 6dm1A-5weoA:
56.1
6dm1D-5weoA:
55.9		 6dm1A-5weoA:
100.00
6dm1D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.44A 6dm1B-5weoA:
55.9
6dm1C-5weoA:
56.1		 6dm1B-5weoA:
100.00
6dm1C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.28A 6dm1B-5weoA:
55.9
6dm1C-5weoA:
56.1		 6dm1B-5weoA:
100.00
6dm1C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		8 / 11 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.43A 6dm1A-5weoA:
56.1
6dm1D-5weoA:
55.9		 6dm1A-5weoA:
100.00
6dm1D-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.31A 6dm2A-5weoA:
56.2
6dm2D-5weoA:
56.1		 6dm2A-5weoA:
100.00
6dm2D-5weoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 MET A 107
SER A 108
LEU A 239
LEU A 247
LYS A 251
 None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.76A 6dm2B-3h6tA:
35.6
6dm2C-3h6tA:
29.1		 6dm2B-3h6tA:
15.44
6dm2C-3h6tA:
15.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.47A 6dm2B-5weoA:
56.1
6dm2C-5weoA:
56.2		 6dm2B-5weoA:
100.00
6dm2C-5weoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 9 PRO A 494
MET A 496
SER A 497
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ  A1302 (-4.5A)
CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.24A 6dm2B-5weoA:
56.1
6dm2C-5weoA:
56.2		 6dm2B-5weoA:
100.00
6dm2C-5weoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h6t GLUTAMATE RECEPTOR 2
(Rattus
norvegicus) 		5 / 10 MET A 107
SER A 108
LEU A 239
LEU A 247
LYS A 251
 None
CYZ  A 265 (-2.8A)
CYZ  A 265 (-4.7A)
CYZ  A 265 (-4.3A)
CYZ  A 265 ( 4.4A)
 0.76A 6dm2A-3h6tA:
29.1
6dm2D-3h6tA:
35.9		 6dm2A-3h6tA:
15.44
6dm2D-3h6tA:
15.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA
(Mus
musculus;
Rattus
norvegicus) 		7 / 10 MET A 496
SER A 497
LEU A 751
SER A 754
LEU A 759
ASP A 760
LYS A 763
 CYZ  A1302 (-4.3A)
CYZ  A1302 (-3.2A)
None
CYZ  A1302 ( 4.1A)
None
CYZ  A1302 (-3.8A)
CYZ  A1302 (-2.9A)
 0.43A 6dm2A-5weoA:
56.2
6dm2D-5weoA:
56.1		 6dm2A-5weoA:
100.00
6dm2D-5weoA:
100.00