SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CYC'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HSH_A_MK1A401_2 (HIV-II PROTEASE)	4xxk	PHYCOBILIPROTEIN APCE (Nostoc sp. PCC 7120)	5 / 9	ALA A 204 GLY A 198 ILE A 192 ILE A 79 ILE A 75	None None CYC A 301 (-4.3A) None None	0.95A	1hshB-4xxkA: undetectable	1hshB-4xxkA: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IWH_A_PEMA501_1 (HEMOGLOBIN ALPHA CHAIN)	5b13	PHYCOERYTHRIN ALPHA SUBUNIT (Palmaria palmata)	4 / 6	ALA A 50 LYS A 53 ASP A 57 ALA A 58	CYC A 201 ( 4.0A) None None None	0.36A	1iwhA-5b13A: 8.8	1iwhA-5b13A: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_1 (ALPHA-AMYLASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	ALA B 121 VAL B 124 GLY B 123 ALA B 83 ILE B 56	None CYC B 175 ( 4.7A) None CYC B 175 (-3.4A) None	1.23A	1kxhA-1liaB: undetectable	1kxhA-1liaB: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7F_A_BCZA801_1 (NEURAMINIDASE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	3 / 3	ARG A 373 ARG A 85 ARG A 383	CYC A1422 ( 4.3A) None None	1.08A	1l7fA-4bwiA: undetectable	1l7fA-4bwiA: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7H_A_BCZA801_1 (NEURAMINIDASE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	3 / 3	ARG A 373 ARG A 85 ARG A 383	CYC A1422 ( 4.3A) None None	1.08A	1l7hA-4bwiA: undetectable	1l7hA-4bwiA: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_A_FUAA702_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	4h0m	C-PHYCOCYANIN ALPHA CHAIN C-PHYCOCYANIN BETA CHAIN (Synechococcus elongatus)	5 / 12	THR B 40 TYR B 163 PHE A 31 LEU B 30 ALA B 102	CYC B 202 ( 4.7A) None None None None	1.34A	1q23A-4h0mB: undetectable 1q23B-4h0mB: undetectable	1q23A-4h0mB: 24.68 1q23B-4h0mB: 24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_B_FK5B401_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	5 / 10	TYR A 133 ASP A 79 ARG A 383 VAL A 139 ILE A 156	CYC A1422 (-4.1A) CYC A1422 (-4.0A) None None CYC A1422 ( 4.7A)	1.47A	1q6iB-4bwiA: undetectable	1q6iB-4bwiA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T3R_A_017A1200_1 (PROTEASE RETROPEPSIN)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 10	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	0.92A	1t3rA-1liaB: undetectable	1t3rA-1liaB: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T7I_A_017A200_1 (POL POLYPROTEIN)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 10	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	0.99A	1t7iA-1liaB: undetectable	1t7iA-1liaB: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB6_0 (GRAMICIDIN A)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	ALA A 622 VAL A 639 TRP A 643	CYC A 800 ( 4.6A) None None	0.91A	1tkqB-6bhnA: undetectable	1tkqB-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_D_IMND476_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	3jbb	ALLOPHYCOCYANIN BETA CHAIN (Halomicronema hongdechloris)	5 / 12	THR B 126 ILE B 156 TYR B 116 ILE B 123 LEU B 112	CYC B 201 (-4.2A) None CYC B 201 (-4.9A) SO4 B 203 (-4.2A) CYC B 201 ( 4.4A)	1.04A	1z9hD-3jbbB: undetectable	1z9hD-3jbbB: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_D_IMND476_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	4f0u	ALLOPHYCOCYANIN, BETA SUBUNIT (Synechococcus elongatus)	5 / 12	THR B 129 ILE B 169 TYR B 119 ILE B 126 LEU B 115	CYC B 201 (-4.2A) None None None CYC B 201 ( 4.9A)	1.01A	1z9hD-4f0uB: undetectable	1z9hD-4f0uB: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_D_IMND476_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	5tjf	ALLOPHYCOCYANIN BETA SUBUNIT (Gracilaria chilensis)	5 / 12	THR B 126 ILE B 156 TYR B 116 ILE B 123 LEU B 112	CYC B 201 (-2.8A) None CYC B 201 ( 4.1A) PEG B 203 (-3.1A) CYC B 201 (-4.4A)	1.01A	1z9hD-5tjfB: undetectable	1z9hD-5tjfB: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ACL_E_REAE504_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2vjt	ALLOPHYCOCYANIN BETA SUBUNIT (Gloeobacter violaceus)	5 / 11	ILE B 52 ALA B 55 ALA B 56 LEU B 60 ALA B 132	None None None CYC B1081 (-4.7A) None	1.11A	2aclE-2vjtB: 3.2	2aclE-2vjtB: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	4n6s	C-PHYCOCYANIN BETA SUBUNIT (Thermosynechococ cus vulcanus)	3 / 3	SER B 46 ASP B 39 CYH B 155	None CYC B 202 (-3.0A) CYC B 202 (-1.8A)	1.12A	2br4E-4n6sB: undetectable	2br4E-4n6sB: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	5b13	PHYCOERYTHRIN BETA SUBUNIT (Palmaria palmata)	3 / 3	SER G 46 ASP G 39 CYH G 158	None CYC G 202 (-3.2A) CYC G 202 (-1.7A)	1.09A	2br4E-5b13G: undetectable	2br4E-5b13G: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FKE_A_FK5A108_1 (FK506 BINDING PROTEIN)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	5 / 11	TYR A 133 ASP A 79 ARG A 383 VAL A 139 ILE A 156	CYC A1422 (-4.1A) CYC A1422 (-4.0A) None None CYC A1422 ( 4.7A)	1.40A	2fkeA-4bwiA: undetectable	2fkeA-4bwiA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	5 / 12	TYR A 668 LEU A 714 ASP A 657 HIS A 659 ALA A 699	CYC A 800 (-3.9A) None CYC A 800 (-2.1A) CYC A 800 (-3.6A) None	1.12A	2g72A-6bhnA: undetectable	2g72A-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_A_STIA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4f0u	ALLOPHYCOCYANIN ALPHA CHAIN ALLOPHYCOCYANIN, BETA SUBUNIT (Synechococcus elongatus)	4 / 6	LEU B 24 VAL A 52 ILE A 44 ARG A 86	None None None CYC A 201 (-3.0A)	0.92A	2hyyA-4f0uB: undetectable	2hyyA-4f0uB: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_A_STIA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	4h0m	C-PHYCOCYANIN ALPHA CHAIN C-PHYCOCYANIN BETA CHAIN (Synechococcus elongatus)	4 / 6	LEU A 24 VAL B 52 ILE B 44 ARG B 84	CYC B 202 ( 4.6A) None None CYC B 201 (-2.8A)	1.02A	2hyyA-4h0mA: undetectable	2hyyA-4h0mA: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OCU_A_TYLA3001_1 (LACTOTRANSFERRIN)	2bv8	C-PHYCOCYANIN BETA SUBUNIT (Gracilaria chilensis)	3 / 3	LEU B 113 TYR B 117 GLY B 121	CYC B1174 (-4.1A) None MEN B 72 ( 4.7A)	0.63A	2ocuA-2bv8B: undetectable	2ocuA-2bv8B: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OCU_A_TYLA3001_1 (LACTOTRANSFERRIN)	2uun	C-PHYCOCYANIN (Leptolyngbya sp.)	3 / 3	LEU B 113 TYR B 117 GLY B 121	CYC B 184 (-3.9A) None None	0.60A	2ocuA-2uunB: undetectable	2ocuA-2uunB: 19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBL_A_CAMA517_0 (CYTOCHROME P450-CAM)	4h0m	C-PHYCOCYANIN BETA CHAIN (Synechococcus elongatus)	4 / 7	LEU B 90 VAL B 93 THR B 94 VAL B 142	None None None CYC B 202 (-4.2A)	0.93A	2qblA-4h0mB: undetectable	2qblA-4h0mB: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UXO_B_TACB1211_1 (HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR)	2c7l	PHYCOERYTHROCYANIN ALPHA CHAIN PHYCOERYTHROCYANIN BETA CHAIN (Mastigocladus laminosus)	5 / 11	LEU B 38 LEU B 160 VAL B 97 LEU A 24 ILE B 51	CYC B1174 (-3.6A) None None CYC B1174 (-4.7A) None	1.11A	2uxoB-2c7lB: 0.0	2uxoB-2c7lB: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VL2_A_BEZA1162_0 (PEROXIREDOXIN-5)	2c7l	PHYCOERYTHROCYANIN BETA CHAIN (Mastigocladus laminosus)	5 / 10	THR B 122 PRO B 123 GLY B 124 LEU B 86 GLY B 130	CYC B1173 (-3.5A) None None CYC B1173 (-4.1A) None	1.08A	2vl2A-2c7lB: undetectable 2vl2C-2c7lB: undetectable	2vl2A-2c7lB: 22.06 2vl2C-2c7lB: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YS6_A_GLYA431_0 (PHOSPHORIBOSYLGLYCIN AMIDE SYNTHETASE)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 8	ASP A 207 TYR A 176 GLY A 184 PRO A 204	CYC A1521 (-3.9A) None None None	0.93A	2ys6A-2veaA: undetectable	2ys6A-2veaA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YS6_A_GLYA431_0 (PHOSPHORIBOSYLGLYCIN AMIDE SYNTHETASE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	4 / 8	ASP A 79 TYR A 47 GLY A 55 PRO A 76	CYC A1422 (-4.0A) CYC A1422 (-4.2A) None None	1.04A	2ys6A-4bwiA: undetectable	2ys6A-4bwiA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A7E_A_SAMA216_1 (CATECHOL O-METHYLTRANSFERASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	4 / 6	GLY B 153 ILE B 151 GLU B 152 ASP B 154	CYC B 176 (-3.7A) CYC B 176 (-3.8A) None None	0.96A	3a7eA-1liaB: undetectable	3a7eA-1liaB: 25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1100_1 (SERUM ALBUMIN)	2uun	C-PHYCOCYANIN (Leptolyngbya sp.)	4 / 4	LEU B 105 ARG B 114 LEU B 113 ALA B 169	None None CYC B 184 (-3.9A) None	1.20A	3b9mA-2uunB: 2.4	3b9mA-2uunB: 14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC552_1 (GLUTAMATE DEHYDROGENASE)	1all	ALLOPHYCOCYANIN (Arthrospira platensis)	3 / 3	TYR A 91 TYR A 168 GLY A 111	CYC A 175 (-4.2A) None CYC A 175 ( 3.9A)	0.69A	3eteB-1allA: undetectable 3eteD-1allA: undetectable 3eteF-1allA: undetectable	3eteB-1allA: 16.48 3eteD-1allA: 16.48 3eteF-1allA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC552_1 (GLUTAMATE DEHYDROGENASE)	2vjt	ALLOPHYCOCYANIN ALPHA SUBUNIT (Gloeobacter violaceus)	3 / 3	TYR A 88 TYR A 155 GLY A 108	CYC A1081 (-4.1A) None CYC A1081 ( 4.0A)	0.73A	3eteB-2vjtA: undetectable 3eteD-2vjtA: undetectable 3eteF-2vjtA: undetectable	3eteB-2vjtA: 14.62 3eteD-2vjtA: 14.62 3eteF-2vjtA: 14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IHZ_A_FK5A501_1 (70 KDA PEPTIDYLPROLYL ISOMERASE, PUTATIVE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	5 / 10	TYR A 133 ASP A 79 ARG A 383 VAL A 139 ILE A 156	CYC A1422 (-4.1A) CYC A1422 (-4.0A) None None CYC A1422 ( 4.7A)	1.40A	3ihzA-4bwiA: undetectable	3ihzA-4bwiA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_B_EAAB213_1 (GLUTATHIONE S-TRANSFERASE P)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	4 / 7	TYR A 116 VAL A 112 VAL A 156 GLY A 108	None None None CYC A 201 ( 3.8A)	1.13A	3kmoB-4rmpA: undetectable	3kmoB-4rmpA: 26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXI_A_CAMA423_0 (CYTOCHROME P450)	3mwn	PHYCOERYTHRIN (Phormidium tenue)	5 / 10	THR A1134 LEU A1159 LEU A1156 VAL A1052 VAL A1051	None None None None CYC A3002 ( 4.5A)	1.25A	3lxiA-3mwnA: undetectable	3lxiA-3mwnA: 13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZV_A_017A200_1 (HIV-1 PROTEASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 10	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	0.96A	3lzvA-1liaB: undetectable	3lzvA-1liaB: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_1 (HIV-1 PROTEASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 11	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	0.97A	3spkA-1liaB: undetectable	3spkA-1liaB: 15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_B_TPVB100_2 (HIV-1 PROTEASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	1.01A	3spkB-1liaB: undetectable	3spkB-1liaB: 15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U5K_D_08JD4_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	2vml	PHYCOCYANIN ALPHA CHAIN PHYCOCYANIN BETA CHAIN (Gloeobacter violaceus)	4 / 8	VAL B 41 LEU A 24 LEU B 38 ILE A 5	None CYC B1153 (-4.1A) CYC B1153 (-3.8A) None	0.86A	3u5kD-2vmlB: undetectable	3u5kD-2vmlB: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U7S_A_017A202_1 (POL POLYPROTEIN)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 9	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	1.12A	3u7sA-1liaB: undetectable	3u7sA-1liaB: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	5 / 12	ILE A 208 ALA A 212 ALA A 256 LEU A 264 ILE A 224	CYC A1521 (-4.0A) CYC A1521 ( 3.8A) CYC A1521 (-3.9A) None None	0.70A	3uvvA-2veaA: undetectable	3uvvA-2veaA: 20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9K_B_CAMB424_0 (CYTOCHROME P450)	3mwn	PHYCOERYTHRIN (Phormidium tenue)	5 / 9	THR A1134 LEU A1159 LEU A1156 VAL A1052 VAL A1051	None None None None CYC A3002 ( 4.5A)	1.26A	4c9kB-3mwnA: undetectable	4c9kB-3mwnA: 13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_A_CAMA423_0 (CYTOCHROME P450)	3mwn	PHYCOERYTHRIN (Phormidium tenue)	5 / 9	THR A1134 LEU A1159 LEU A1156 VAL A1052 VAL A1051	None None None None CYC A3002 ( 4.5A)	1.26A	4c9pA-3mwnA: undetectable	4c9pA-3mwnA: 15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	1eyx	R-PHYCOERYTHRIN (Gracilaria chilensis)	4 / 7	LEU A 44 GLY A 149 TYR A 152 SER A 153	CYC A 168 (-4.2A) None CYC A 168 (-4.3A) None	0.63A	4cp3A-1eyxA: 0.0 4cp3B-1eyxA: undetectable	4cp3A-1eyxA: 21.82 4cp3B-1eyxA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF3_A_SAMA301_1 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	5m85	SENSORY TRANSDUCTION HISTIDINE KINASE (Synechocystis sp. PCC 6803)	3 / 3	TYR A 509 THR A 543 GLU A 513	NA A 703 ( 4.3A) CYC A 701 ( 4.0A) None	0.81A	4df3A-5m85A: undetectable	4df3A-5m85A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF3_B_SAMB301_1 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	5m85	SENSORY TRANSDUCTION HISTIDINE KINASE (Synechocystis sp. PCC 6803)	3 / 3	TYR A 509 THR A 543 GLU A 513	NA A 703 ( 4.3A) CYC A 701 ( 4.0A) None	0.77A	4df3B-5m85A: undetectable	4df3B-5m85A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5tjf	ALLOPHYCOCYANIN ALPHA SUBUNIT (Gracilaria chilensis)	4 / 8	GLN A 161 ILE A 123 GLY A 129 GLU A 128	None None CYC A 201 ( 4.6A) None	0.96A	4fgjA-5tjfA: undetectable 4fgjB-5tjfA: undetectable	4fgjA-5tjfA: 20.85 4fgjB-5tjfA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_B_CLQB303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	5 / 11	HIS A 130 PHE A 49 GLY A 89 MET A 148 GLU A 87	CYC A1422 (-3.5A) None GLU A1427 (-3.2A) None None	1.26A	4fglA-4bwiA: undetectable 4fglB-4bwiA: undetectable	4fglA-4bwiA: 20.59 4fglB-4bwiA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	PHE A 133 TYR A 119 SER A 126 CYH A 84 ILE A 88	None None None CYC A 175 (-1.8A) None	1.09A	4krhA-1liaA: undetectable	4krhA-1liaA: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	PHE A 133 TYR A 119 SER A 126 CYH A 84 ILE A 88	None None None CYC A 175 (-1.8A) None	1.15A	4krhB-1liaA: undetectable	4krhB-1liaA: 17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L7I_B_SAMB501_0 (S-ADENOSYLMETHIONINE SYNTHASE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	4 / 8	ASN A 90 ARG A 92 LEU A 153 ILE A 80	GLU A1427 (-3.2A) None GLU A1427 ( 4.9A) CYC A1422 (-4.0A)	1.09A	4l7iA-4bwiA: undetectable	4l7iA-4bwiA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LAJ_B_ACAB512_1 (HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN)	5m85	SENSORY TRANSDUCTION HISTIDINE KINASE (Synechocystis sp. PCC 6803)	4 / 6	ARG A 508 GLY A 507 PRO A 545 HIS A 576	CYC A 701 ( 3.7A) None None None	0.81A	4lajA-5m85A: undetectable 4lajB-5m85A: undetectable	4lajA-5m85A: 10.34 4lajB-5m85A: 10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M93_B_ACTB303_0 (S25-26 FAB (IGG1K) HEAVY CHAIN S25-26 FAB (IGG1K) LIGHT CHAIN)	5b13	PHYCOERYTHRIN BETA SUBUNIT (Palmaria palmata)	4 / 5	GLY G 144 SER G 143 ALA G 140 PHE G 43	CYC G 202 ( 3.9A) None PUB G 203 ( 3.9A) None	1.06A	4m93B-5b13G: undetectable 4m93C-5b13G: undetectable	4m93B-5b13G: 21.00 4m93C-5b13G: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	5m85	SENSORY TRANSDUCTION HISTIDINE KINASE (Synechocystis sp. PCC 6803)	4 / 6	GLU A 451 THR A 448 GLN A 581 THR A 543	None None None CYC A 701 ( 4.0A)	1.24A	4pfjB-5m85A: undetectable	4pfjB-5m85A: 10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1X_A_017A101_1 (ASPARTYL PROTEASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 11	LEU B 122 ALA B 83 ILE B 56 GLY B 88 ILE B 90	CYC B 175 ( 4.5A) CYC B 175 (-3.4A) None CYC B 175 ( 4.9A) CYC B 175 (-3.7A)	0.91A	4q1xA-1liaB: undetectable	4q1xA-1liaB: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_0 (RETINOL-BINDING PROTEIN 2)	4f0u	ALLOPHYCOCYANIN, BETA SUBUNIT (Synechococcus elongatus)	5 / 12	ALA B 98 THR B 129 VAL B 130 LEU B 115 LEU B 112	None CYC B 201 (-4.2A) None CYC B 201 ( 4.9A) None	1.16A	4qzuC-4f0uB: undetectable	4qzuC-4f0uB: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	GLU A 637 ALA A 636 PHE A 634	None None CYC A 800 (-3.9A)	0.64A	4v1fA-6bhnA: undetectable	4v1fA-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	GLU A 637 ALA A 636 PHE A 634	None None CYC A 800 (-3.9A)	0.62A	4v1fC-6bhnA: undetectable	4v1fC-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	5tjf	ALLOPHYCOCYANIN ALPHA SUBUNIT (Gracilaria chilensis)	4 / 4	TYR A 116 THR A 121 GLY A 125 LEU A 85	CYC A 201 (-4.6A) CYC A 201 (-3.7A) CYC A 201 (-3.0A) CYC A 201 ( 3.6A)	1.25A	4w5nA-5tjfA: undetectable	4w5nA-5tjfA: 12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_2 (ESTROGEN RECEPTOR)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 5	LEU A 286 GLU A 306 LEU A 215 HIS A 260	CYC A1521 ( 4.9A) None None CYC A1521 (-3.4A)	1.12A	4xi3B-2veaA: undetectable	4xi3B-2veaA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_B_IMNB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2vjt	ALLOPHYCOCYANIN BETA SUBUNIT (Gloeobacter violaceus)	5 / 11	GLY B 138 ALA B 55 MET B 85 LEU B 89 MET B 96	None None CYC B1081 ( 4.0A) None None	1.14A	4xumB-2vjtB: undetectable	4xumB-2vjtB: 17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 7	ARG A 472 ARG A 172 TYR A 203 TYR A 263	None None CYC A1521 (-3.9A) CYC A1521 (-3.9A)	1.46A	5a06A-2veaA: undetectable	5a06A-2veaA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_C_SORC1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 7	ARG A 472 ARG A 172 TYR A 203 TYR A 263	None None CYC A1521 (-3.9A) CYC A1521 (-3.9A)	1.48A	5a06C-2veaA: undetectable	5a06C-2veaA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_A_ACTA1923_0 (BETA-XYLOSIDASE)	3jbb	ALLOPHYCOCYANIN BETA CHAIN (Halomicronema hongdechloris)	3 / 3	ASP B 84 ARG B 83 TYR B 87	CYC B 201 (-2.7A) None CYC B 201 (-4.2A)	1.03A	5a7mA-3jbbB: undetectable	5a7mA-3jbbB: 11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A7M_B_ACTB1924_0 (BETA-XYLOSIDASE)	3jbb	ALLOPHYCOCYANIN BETA CHAIN (Halomicronema hongdechloris)	3 / 3	ASP B 84 ARG B 83 TYR B 87	CYC B 201 (-2.7A) None CYC B 201 (-4.2A)	1.03A	5a7mB-3jbbB: undetectable	5a7mB-3jbbB: 11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_R_BEZR801_1 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 8	SER A 272 ALA A 271 LEU A 264 LEU A 261	CYC A1521 ( 3.7A) None None None	1.05A	5dzkd-2veaA: undetectable 5dzkr-2veaA: undetectable	5dzkd-2veaA: 18.41 5dzkr-2veaA: 3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_B_010B607_0 (HNL ISOENZYME 5)	4rmp	ALLOPHYCOCYANIN (Phormidium rubidum)	5 / 10	ALA A 129 ALA A 125 VAL A 65 LEU A 82 VAL A 66	CYC A 201 ( 3.7A) CYC A 201 (-3.4A) CYC A 201 (-4.1A) None None	1.44A	5eb5B-4rmpA: undetectable	5eb5B-4rmpA: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESJ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3w2z	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Nostoc sp. PCC 7120)	4 / 8	TYR A 59 ILE A 137 GLY A 101 THR A 98	CYC A 201 (-4.0A) CYC A 201 (-4.7A) None None	0.93A	5esjA-3w2zA: undetectable	5esjA-3w2zA: 14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HS1_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3w2z	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Nostoc sp. PCC 7120)	4 / 8	TYR A 59 ILE A 137 GLY A 101 THR A 98	CYC A 201 (-4.0A) CYC A 201 (-4.7A) None None	0.88A	5hs1A-3w2zA: undetectable	5hs1A-3w2zA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JI0_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	5tou	PHYCOCYANIN BETA-1 SUBUNIT (Pseudanabaena sp. lw0831)	5 / 11	ILE D 131 LEU D 90 ALA D 55 CYH D 109 LEU D 105	None None None CYC D 202 ( 3.9A) None	1.24A	5ji0A-5touD: undetectable	5ji0A-5touD: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOX_A_RFPA502_2 (PENTACHLOROPHENOL 4-MONOOXYGENASE)	3w2z	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Nostoc sp. PCC 7120)	3 / 3	VAL A 23 ARG A 102 PRO A 139	None CYC A 201 (-3.7A) None	0.86A	5koxA-3w2zA: undetectable	5koxA-3w2zA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	ASN B 63 CYH B 75 ARG B 80 CYH B 84 LEU B 66	None CYC B 175 (-3.5A) CYC B 175 (-3.9A) CYC B 175 (-1.8A) CYC B 175 ( 4.8A)	1.42A	5lsuA-1liaB: undetectable	5lsuA-1liaB: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	5 / 12	GLY B 123 ASN B 63 CYH B 75 CYH B 84 LEU B 66	None None CYC B 175 (-3.5A) CYC B 175 (-1.8A) CYC B 175 ( 4.8A)	1.27A	5lsuA-1liaB: undetectable	5lsuA-1liaB: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	4lms	CRYPTOPHYTE PHYCOCYANIN (BETA CHAIN) (Chroomonas sp.)	5 / 12	ASN B 63 CYH B 73 ARG B 78 CYH B 82 LEU B 66	None CYC B 203 (-3.6A) None CYC B 203 (-1.8A) CYC B 203 ( 4.8A)	1.34A	5lsuA-4lmsB: undetectable	5lsuA-4lmsB: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	4lms	CRYPTOPHYTE PHYCOCYANIN (BETA CHAIN) (Chroomonas sp.)	5 / 12	GLY B 121 ASN B 63 CYH B 73 CYH B 82 LEU B 66	MEN B 72 ( 4.6A) None CYC B 203 (-3.6A) CYC B 203 (-1.8A) CYC B 203 ( 4.8A)	1.34A	5lsuA-4lmsB: undetectable	5lsuA-4lmsB: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZJ_A_TEPA2401_1 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	3mwn	PHYCOERYTHRIN (Phormidium tenue)	4 / 8	LEU A1138 MET A1144 LEU A1044 ILE A1093	CYC A3002 (-4.0A) None CYC A3002 (-3.9A) None	0.98A	5mzjA-3mwnA: undetectable	5mzjA-3mwnA: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMW_B_RBFB201_1 (GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE)	1lia	R-PHYCOERYTHRIN (Polysiphonia urceolata)	4 / 7	VAL A 52 ARG A 93 TYR B 18 LEU A 107	None CYC A 175 ( 4.9A) None None	1.01A	5umwB-1liaA: undetectable 5umwE-1liaA: undetectable	5umwB-1liaA: 18.90 5umwE-1liaA: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	3mwn	PHYCOERYTHRIN (Phormidium tenue)	4 / 5	VAL A1051 LEU A1156 CYH A1153 ASP A1143	CYC A3002 ( 4.5A) None None CYC A3002 ( 3.8A)	1.29A	5vcvA-3mwnA: undetectable	5vcvA-3mwnA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7J_A_TESA502_0 (CYTOCHROME P450)	2vml	PHYCOCYANIN ALPHA CHAIN (Gloeobacter violaceus)	4 / 7	LEU A 19 LEU A 24 ALA A 26 ALA A 27	None CYC B1153 (-4.1A) None None	0.75A	6a7jA-2vmlA: undetectable	6a7jA-2vmlA: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D8P_B_ACTB804_0 (UNCHARACTERIZED PROTEIN)	2vea	PHYTOCHROME-LIKE PROTEIN CPH1 (Synechocystis sp. PCC 6803)	4 / 4	HIS A 260 VAL A 227 LEU A 264 ALA A 256	CYC A1521 (-3.4A) None None CYC A1521 (-3.9A)	1.29A	6d8pB-2veaA: undetectable	6d8pB-2veaA: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_1 (-)	4po5	ALLOPHYCOCYANIN SUBUNIT ALPHA-B (Synechocystis sp. PCC 6803)	5 / 10	THR A 106 GLY A 108 LEU A 109 SER A 2 VAL A 130	None CYC A 201 ( 4.4A) None None None	1.25A	6gnfC-4po5A: undetectable	6gnfC-4po5A: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6JMJ_A_ASCA201_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	4f0u	ALLOPHYCOCYANIN, BETA SUBUNIT (Synechococcus elongatus)	4 / 5	GLY B 127 THR B 129 SER B 171 SER B 170	None CYC B 201 (-4.2A) None None	1.12A	6jmjA-4f0uB: undetectable	6jmjA-4f0uB: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_D_FK5D201_1 (PEPTIDYLPROLYL ISOMERASE)	4bwi	PHYTOCHROME-LIKE PROTEIN CPH2 (Synechocystis sp.)	5 / 10	TYR A 133 ASP A 79 ARG A 383 VAL A 139 ILE A 156	CYC A1422 (-4.1A) CYC A1422 (-4.0A) None None CYC A1422 ( 4.7A)	1.45A	6mkeD-4bwiA: undetectable	6mkeD-4bwiA: 15.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HSH_A_MK1A401_2","HIV-II PROTEASE;HIV-II PROTEASE","4xxk","PHYCOBILIPROTEIN APCE","Nostoc sp. PCC 7120",5,"ALA A 204;GLY A 198;ILE A 192;ILE A  79;ILE A  75","None;None;CYC A 301 (-4.3A);None;None","0.95A","1hshB-4xxkA:undetectable",null],["1IWH_A_PEMA501_1","HEMOGLOBIN ALPHA CHAIN","5b13","PHYCOERYTHRIN ALPHA SUBUNIT","Palmaria palmata",4,"ALA A  50;LYS A  53;ASP A  57;ALA A  58","CYC A 201 ( 4.0A);None;None;None","0.36A","1iwhA-5b13A:8.8","1hshB-4xxkA:22.44"],["1KXH_A_ACRA598_1","ALPHA-AMYLASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"ALA B 121;VAL B 124;GLY B 123;ALA B  83;ILE B  56","None;CYC B 175 ( 4.7A);None;CYC B 175 (-3.4A);None","1.23A","1kxhA-1liaB:undetectable","1iwhA-5b13A:20.36"],["1L7F_A_BCZA801_1","NEURAMINIDASE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",3,"ARG A 373;ARG A  85;ARG A 383","CYC A1422 ( 4.3A);None;None","1.08A","1l7fA-4bwiA:undetectable","1kxhA-1liaB:18.53"],["1L7H_A_BCZA801_1","NEURAMINIDASE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",3,"ARG A 373;ARG A  85;ARG A 383","CYC A1422 ( 4.3A);None;None","1.08A","1l7hA-4bwiA:undetectable","1l7fA-4bwiA:22.44"],["1Q23_A_FUAA702_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","4h0m","C-PHYCOCYANIN ALPHA CHAIN;C-PHYCOCYANIN BETA CHAIN","Synechococcus elongatus",5,"THR B  40;TYR B 163;PHE A  31;LEU B  30;ALA B 102","CYC B 202 ( 4.7A);None;None;None;None","1.34A","1q23A-4h0mB:undetectable;1q23B-4h0mB:undetectable","1l7hA-4bwiA:22.44"],["1Q6I_B_FK5B401_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",5,"TYR A 133;ASP A  79;ARG A 383;VAL A 139;ILE A 156","CYC A1422 (-4.1A);CYC A1422 (-4.0A);None;None;CYC A1422 ( 4.7A)","1.47A","1q6iB-4bwiA:undetectable","1q23A-4h0mB:24.68;1q23B-4h0mB:24.68"],["1T3R_A_017A1200_1","PROTEASE RETROPEPSIN","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","0.92A","1t3rA-1liaB:undetectable","1q6iB-4bwiA:21.32"],["1T7I_A_017A200_1","POL POLYPROTEIN","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","0.99A","1t7iA-1liaB:undetectable","1t3rA-1liaB:16.67"],["1TKQ_B_DVAB6_0","GRAMICIDIN A","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"ALA A 622;VAL A 639;TRP A 643","CYC A 800 ( 4.6A);None;None","0.91A","1tkqB-6bhnA:undetectable","1t7iA-1liaB:14.12"],["1Z9H_D_IMND476_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","3jbb","ALLOPHYCOCYANIN BETA CHAIN","Halomicronema hongdechloris",5,"THR B 126;ILE B 156;TYR B 116;ILE B 123;LEU B 112","CYC B 201 (-4.2A);None;CYC B 201 (-4.9A);SO4 B 203 (-4.2A);CYC B 201 ( 4.4A)","1.04A","1z9hD-3jbbB:undetectable","1tkqB-6bhnA:undetectable"],["1Z9H_D_IMND476_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","4f0u","ALLOPHYCOCYANIN, BETA SUBUNIT","Synechococcus elongatus",5,"THR B 129;ILE B 169;TYR B 119;ILE B 126;LEU B 115","CYC B 201 (-4.2A);None;None;None;CYC B 201 ( 4.9A)","1.01A","1z9hD-4f0uB:undetectable","1z9hD-3jbbB:20.21"],["1Z9H_D_IMND476_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","5tjf","ALLOPHYCOCYANIN BETA SUBUNIT","Gracilaria chilensis",5,"THR B 126;ILE B 156;TYR B 116;ILE B 123;LEU B 112","CYC B 201 (-2.8A);None;CYC B 201 ( 4.1A);PEG B 203 (-3.1A);CYC B 201 (-4.4A)","1.01A","1z9hD-5tjfB:undetectable","1z9hD-4f0uB:20.00"],["2ACL_E_REAE504_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2vjt","ALLOPHYCOCYANIN BETA SUBUNIT","Gloeobacter violaceus",5,"ILE B  52;ALA B  55;ALA B  56;LEU B  60;ALA B 132","None;None;None;CYC B1081 (-4.7A);None","1.11A","2aclE-2vjtB:3.2","1z9hD-5tjfB:18.97"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","4n6s","C-PHYCOCYANIN BETA SUBUNIT","Thermosynechococcus vulcanus",3,"SER B  46;ASP B  39;CYH B 155","None;CYC B 202 (-3.0A);CYC B 202 (-1.8A)","1.12A","2br4E-4n6sB:undetectable","2aclE-2vjtB:24.20"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","5b13","PHYCOERYTHRIN BETA SUBUNIT","Palmaria palmata",3,"SER G  46;ASP G  39;CYH G 158","None;CYC G 202 (-3.2A);CYC G 202 (-1.7A)","1.09A","2br4E-5b13G:undetectable","2br4E-4n6sB:21.72"],["2FKE_A_FK5A108_1","FK506 BINDING PROTEIN","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",5,"TYR A 133;ASP A  79;ARG A 383;VAL A 139;ILE A 156","CYC A1422 (-4.1A);CYC A1422 (-4.0A);None;None;CYC A1422 ( 4.7A)","1.40A","2fkeA-4bwiA:undetectable","2br4E-5b13G:21.22"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",5,"TYR A 668;LEU A 714;ASP A 657;HIS A 659;ALA A 699","CYC A 800 (-3.9A);None;CYC A 800 (-2.1A);CYC A 800 (-3.6A);None","1.12A","2g72A-6bhnA:undetectable","2fkeA-4bwiA:14.29"],["2HYY_A_STIA600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4f0u","ALLOPHYCOCYANIN ALPHA CHAIN;ALLOPHYCOCYANIN, BETA SUBUNIT","Synechococcus elongatus",4,"LEU B  24;VAL A  52;ILE A  44;ARG A  86","None;None;None;CYC A 201 (-3.0A)","0.92A","2hyyA-4f0uB:undetectable","2g72A-6bhnA:undetectable"],["2HYY_A_STIA600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","4h0m","C-PHYCOCYANIN ALPHA CHAIN;C-PHYCOCYANIN BETA CHAIN","Synechococcus elongatus",4,"LEU A  24;VAL B  52;ILE B  44;ARG B  84","CYC B 202 ( 4.6A);None;None;CYC B 201 (-2.8A)","1.02A","2hyyA-4h0mA:undetectable","2hyyA-4f0uB:20.64"],["2OCU_A_TYLA3001_1","LACTOTRANSFERRIN","2bv8","C-PHYCOCYANIN BETA SUBUNIT","Gracilaria chilensis",3,"LEU B 113;TYR B 117;GLY B 121","CYC B1174 (-4.1A);None;MEN B  72 ( 4.7A)","0.63A","2ocuA-2bv8B:undetectable","2hyyA-4h0mA:16.42"],["2OCU_A_TYLA3001_1","LACTOTRANSFERRIN","2uun","C-PHYCOCYANIN","Leptolyngbya sp.",3,"LEU B 113;TYR B 117;GLY B 121","CYC B 184 (-3.9A);None;None","0.60A","2ocuA-2uunB:undetectable","2ocuA-2bv8B:21.05"],["2QBL_A_CAMA517_0","CYTOCHROME P450-CAM","4h0m","C-PHYCOCYANIN BETA CHAIN","Synechococcus elongatus",4,"LEU B  90;VAL B  93;THR B  94;VAL B 142","None;None;None;CYC B 202 (-4.2A)","0.93A","2qblA-4h0mB:undetectable","2ocuA-2uunB:19.36"],["2UXO_B_TACB1211_1","HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR","2c7l","PHYCOERYTHROCYANIN ALPHA CHAIN;PHYCOERYTHROCYANIN BETA CHAIN","Mastigocladus laminosus",5,"LEU B  38;LEU B 160;VAL B  97;LEU A  24;ILE B  51","CYC B1174 (-3.6A);None;None;CYC B1174 (-4.7A);None","1.11A","2uxoB-2c7lB:0.0","2qblA-4h0mB:17.27"],["2VL2_A_BEZA1162_0","PEROXIREDOXIN-5","2c7l","PHYCOERYTHROCYANIN BETA CHAIN","Mastigocladus laminosus",5,"THR B 122;PRO B 123;GLY B 124;LEU B  86;GLY B 130","CYC B1173 (-3.5A);None;None;CYC B1173 (-4.1A);None","1.08A","2vl2A-2c7lB:undetectable;2vl2C-2c7lB:undetectable","2uxoB-2c7lB:21.43"],["2YS6_A_GLYA431_0","PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"ASP A 207;TYR A 176;GLY A 184;PRO A 204","CYC A1521 (-3.9A);None;None;None","0.93A","2ys6A-2veaA:undetectable","2vl2A-2c7lB:22.06;2vl2C-2c7lB:22.06"],["2YS6_A_GLYA431_0","PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",4,"ASP A  79;TYR A  47;GLY A  55;PRO A  76","CYC A1422 (-4.0A);CYC A1422 (-4.2A);None;None","1.04A","2ys6A-4bwiA:undetectable","2ys6A-2veaA:23.26"],["3A7E_A_SAMA216_1","CATECHOL O-METHYLTRANSFERASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",4,"GLY B 153;ILE B 151;GLU B 152;ASP B 154","CYC B 176 (-3.7A);CYC B 176 (-3.8A);None;None","0.96A","3a7eA-1liaB:undetectable","2ys6A-4bwiA:21.53"],["3B9M_A_SALA1100_1","SERUM ALBUMIN","2uun","C-PHYCOCYANIN","Leptolyngbya sp.",4,"LEU B 105;ARG B 114;LEU B 113;ALA B 169","None;None;CYC B 184 (-3.9A);None","1.20A","3b9mA-2uunB:2.4","3a7eA-1liaB:25.35"],["3ETE_C_H3PC552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","1all","ALLOPHYCOCYANIN","Arthrospira platensis",3,"TYR A  91;TYR A 168;GLY A 111","CYC A 175 (-4.2A);None;CYC A 175 ( 3.9A)","0.69A","3eteB-1allA:undetectable;3eteD-1allA:undetectable;3eteF-1allA:undetectable","3b9mA-2uunB:14.97"],["3ETE_C_H3PC552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","2vjt","ALLOPHYCOCYANIN ALPHA SUBUNIT","Gloeobacter violaceus",3,"TYR A  88;TYR A 155;GLY A 108","CYC A1081 (-4.1A);None;CYC A1081 ( 4.0A)","0.73A","3eteB-2vjtA:undetectable;3eteD-2vjtA:undetectable;3eteF-2vjtA:undetectable","3eteB-1allA:16.48;3eteD-1allA:16.48;3eteF-1allA:16.48"],["3IHZ_A_FK5A501_1","70 KDA PEPTIDYLPROLYL ISOMERASE, PUTATIVE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",5,"TYR A 133;ASP A  79;ARG A 383;VAL A 139;ILE A 156","CYC A1422 (-4.1A);CYC A1422 (-4.0A);None;None;CYC A1422 ( 4.7A)","1.40A","3ihzA-4bwiA:undetectable","3eteB-2vjtA:14.62;3eteD-2vjtA:14.62;3eteF-2vjtA:14.62"],["3KMO_B_EAAB213_1","GLUTATHIONE S-TRANSFERASE P","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",4,"TYR A 116;VAL A 112;VAL A 156;GLY A 108","None;None;None;CYC A 201 ( 3.8A)","1.13A","3kmoB-4rmpA:undetectable","3ihzA-4bwiA:15.84"],["3LXI_A_CAMA423_0","CYTOCHROME P450","3mwn","PHYCOERYTHRIN","Phormidium tenue",5,"THR A1134;LEU A1159;LEU A1156;VAL A1052;VAL A1051","None;None;None;None;CYC A3002 ( 4.5A)","1.25A","3lxiA-3mwnA:undetectable","3kmoB-4rmpA:26.51"],["3LZV_A_017A200_1","HIV-1 PROTEASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","0.96A","3lzvA-1liaB:undetectable","3lxiA-3mwnA:13.48"],["3SPK_A_TPVA100_1","HIV-1 PROTEASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","0.97A","3spkA-1liaB:undetectable","3lzvA-1liaB:17.13"],["3SPK_B_TPVB100_2","HIV-1 PROTEASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","1.01A","3spkB-1liaB:undetectable","3spkA-1liaB:15.56"],["3U5K_D_08JD4_1","BROMODOMAIN-CONTAINING PROTEIN 4","2vml","PHYCOCYANIN ALPHA CHAIN;PHYCOCYANIN BETA CHAIN","Gloeobacter violaceus",4,"VAL B  41;LEU A  24;LEU B  38;ILE A   5","None;CYC B1153 (-4.1A);CYC B1153 (-3.8A);None","0.86A","3u5kD-2vmlB:undetectable","3spkB-1liaB:15.56"],["3U7S_A_017A202_1","POL POLYPROTEIN","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","1.12A","3u7sA-1liaB:undetectable","3u5kD-2vmlB:17.51"],["3UVV_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",5,"ILE A 208;ALA A 212;ALA A 256;LEU A 264;ILE A 224","CYC A1521 (-4.0A);CYC A1521 ( 3.8A);CYC A1521 (-3.9A);None;None","0.70A","3uvvA-2veaA:undetectable","3u7sA-1liaB:20.33"],["4C9K_B_CAMB424_0","CYTOCHROME P450","3mwn","PHYCOERYTHRIN","Phormidium tenue",5,"THR A1134;LEU A1159;LEU A1156;VAL A1052;VAL A1051","None;None;None;None;CYC A3002 ( 4.5A)","1.26A","4c9kB-3mwnA:undetectable","3uvvA-2veaA:20.76"],["4C9P_A_CAMA423_0","CYTOCHROME P450","3mwn","PHYCOERYTHRIN","Phormidium tenue",5,"THR A1134;LEU A1159;LEU A1156;VAL A1052;VAL A1051","None;None;None;None;CYC A3002 ( 4.5A)","1.26A","4c9pA-3mwnA:undetectable","4c9kB-3mwnA:13.48"],["4CP3_B_RBTB1129_1","B-CELL LYMPHOMA 6 PROTEIN;B-CELL LYMPHOMA 6 PROTEIN","1eyx","R-PHYCOERYTHRIN","Gracilaria chilensis",4,"LEU A  44;GLY A 149;TYR A 152;SER A 153","CYC A 168 (-4.2A);None;CYC A 168 (-4.3A);None","0.63A","4cp3A-1eyxA:0.0;4cp3B-1eyxA:undetectable","4c9pA-3mwnA:15.43"],["4DF3_A_SAMA301_1","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","5m85","SENSORY TRANSDUCTION HISTIDINE KINASE","Synechocystis sp. PCC 6803",3,"TYR A 509;THR A 543;GLU A 513"," NA A 703 ( 4.3A);CYC A 701 ( 4.0A);None","0.81A","4df3A-5m85A:undetectable","4cp3A-1eyxA:21.82;4cp3B-1eyxA:21.82"],["4DF3_B_SAMB301_1","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","5m85","SENSORY TRANSDUCTION HISTIDINE KINASE","Synechocystis sp. PCC 6803",3,"TYR A 509;THR A 543;GLU A 513"," NA A 703 ( 4.3A);CYC A 701 ( 4.0A);None","0.77A","4df3B-5m85A:undetectable","4df3A-5m85A:undetectable"],["4FGJ_A_1PQA304_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","5tjf","ALLOPHYCOCYANIN ALPHA SUBUNIT","Gracilaria chilensis",4,"GLN A 161;ILE A 123;GLY A 129;GLU A 128","None;None;CYC A 201 ( 4.6A);None","0.96A","4fgjA-5tjfA:undetectable;4fgjB-5tjfA:undetectable","4df3B-5m85A:undetectable"],["4FGL_B_CLQB303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",5,"HIS A 130;PHE A  49;GLY A  89;MET A 148;GLU A  87","CYC A1422 (-3.5A);None;GLU A1427 (-3.2A);None;None","1.26A","4fglA-4bwiA:undetectable;4fglB-4bwiA:undetectable","4fgjA-5tjfA:20.85;4fgjB-5tjfA:20.85"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"PHE A 133;TYR A 119;SER A 126;CYH A  84;ILE A  88","None;None;None;CYC A 175 (-1.8A);None","1.09A","4krhA-1liaA:undetectable","4fglA-4bwiA:20.59;4fglB-4bwiA:20.59"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"PHE A 133;TYR A 119;SER A 126;CYH A  84;ILE A  88","None;None;None;CYC A 175 (-1.8A);None","1.15A","4krhB-1liaA:undetectable","4krhA-1liaA:17.69"],["4L7I_B_SAMB501_0","S-ADENOSYLMETHIONINE SYNTHASE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",4,"ASN A  90;ARG A  92;LEU A 153;ILE A  80","GLU A1427 (-3.2A);None;GLU A1427 ( 4.9A);CYC A1422 (-4.0A)","1.09A","4l7iA-4bwiA:undetectable","4krhB-1liaA:17.69"],["4LAJ_B_ACAB512_1","HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN;HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN","5m85","SENSORY TRANSDUCTION HISTIDINE KINASE","Synechocystis sp. PCC 6803",4,"ARG A 508;GLY A 507;PRO A 545;HIS A 576","CYC A 701 ( 3.7A);None;None;None","0.81A","4lajA-5m85A:undetectable;4lajB-5m85A:undetectable","4l7iA-4bwiA:22.34"],["4M93_B_ACTB303_0","S25-26 FAB (IGG1K) HEAVY CHAIN;S25-26 FAB (IGG1K) LIGHT CHAIN","5b13","PHYCOERYTHRIN BETA SUBUNIT","Palmaria palmata",4,"GLY G 144;SER G 143;ALA G 140;PHE G  43","CYC G 202 ( 3.9A);None;PUB G 203 ( 3.9A);None","1.06A","4m93B-5b13G:undetectable;4m93C-5b13G:undetectable","4lajA-5m85A:10.34;4lajB-5m85A:10.34"],["4PFJ_B_ADNB502_2","ADENOSYLHOMOCYSTEINASE","5m85","SENSORY TRANSDUCTION HISTIDINE KINASE","Synechocystis sp. PCC 6803",4,"GLU A 451;THR A 448;GLN A 581;THR A 543","None;None;None;CYC A 701 ( 4.0A)","1.24A","4pfjB-5m85A:undetectable","4m93B-5b13G:21.00;4m93C-5b13G:20.70"],["4Q1X_A_017A101_1","ASPARTYL PROTEASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"LEU B 122;ALA B  83;ILE B  56;GLY B  88;ILE B  90","CYC B 175 ( 4.5A);CYC B 175 (-3.4A);None;CYC B 175 ( 4.9A);CYC B 175 (-3.7A)","0.91A","4q1xA-1liaB:undetectable","4pfjB-5m85A:10.72"],["4QZU_C_RTLC201_0","RETINOL-BINDING PROTEIN 2","4f0u","ALLOPHYCOCYANIN, BETA SUBUNIT","Synechococcus elongatus",5,"ALA B  98;THR B 129;VAL B 130;LEU B 115;LEU B 112","None;CYC B 201 (-4.2A);None;CYC B 201 ( 4.9A);None","1.16A","4qzuC-4f0uB:undetectable","4q1xA-1liaB:16.67"],["4V1F_A_BQ1A1087_0","F0F1 ATP SYNTHASE SUBUNIT C","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"GLU A 637;ALA A 636;PHE A 634","None;None;CYC A 800 (-3.9A)","0.64A","4v1fA-6bhnA:undetectable","4qzuC-4f0uB:18.06"],["4V1F_C_BQ1C1087_0","F0F1 ATP SYNTHASE SUBUNIT C","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"GLU A 637;ALA A 636;PHE A 634","None;None;CYC A 800 (-3.9A)","0.62A","4v1fC-6bhnA:undetectable","4v1fA-6bhnA:undetectable"],["4W5N_A_IPHA903_0","PROTEIN ARGONAUTE-2","5tjf","ALLOPHYCOCYANIN ALPHA SUBUNIT","Gracilaria chilensis",4,"TYR A 116;THR A 121;GLY A 125;LEU A  85","CYC A 201 (-4.6A);CYC A 201 (-3.7A);CYC A 201 (-3.0A);CYC A 201 ( 3.6A)","1.25A","4w5nA-5tjfA:undetectable","4v1fC-6bhnA:undetectable"],["4XI3_B_29SB601_2","ESTROGEN RECEPTOR","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"LEU A 286;GLU A 306;LEU A 215;HIS A 260","CYC A1521 ( 4.9A);None;None;CYC A1521 (-3.4A)","1.12A","4xi3B-2veaA:undetectable","4w5nA-5tjfA:12.38"],["4XUM_B_IMNB501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","2vjt","ALLOPHYCOCYANIN BETA SUBUNIT","Gloeobacter violaceus",5,"GLY B 138;ALA B  55;MET B  85;LEU B  89;MET B  96","None;None;CYC B1081 ( 4.0A);None;None","1.14A","4xumB-2vjtB:undetectable","4xi3B-2veaA:18.63"],["5A06_A_SORA1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"ARG A 472;ARG A 172;TYR A 203;TYR A 263","None;None;CYC A1521 (-3.9A);CYC A1521 (-3.9A)","1.46A","5a06A-2veaA:undetectable","4xumB-2vjtB:17.31"],["5A06_C_SORC1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"ARG A 472;ARG A 172;TYR A 203;TYR A 263","None;None;CYC A1521 (-3.9A);CYC A1521 (-3.9A)","1.48A","5a06C-2veaA:undetectable","5a06A-2veaA:21.61"],["5A7M_A_ACTA1923_0","BETA-XYLOSIDASE","3jbb","ALLOPHYCOCYANIN BETA CHAIN","Halomicronema hongdechloris",3,"ASP B  84;ARG B  83;TYR B  87","CYC B 201 (-2.7A);None;CYC B 201 (-4.2A)","1.03A","5a7mA-3jbbB:undetectable","5a06C-2veaA:21.61"],["5A7M_B_ACTB1924_0","BETA-XYLOSIDASE","3jbb","ALLOPHYCOCYANIN BETA CHAIN","Halomicronema hongdechloris",3,"ASP B  84;ARG B  83;TYR B  87","CYC B 201 (-2.7A);None;CYC B 201 (-4.2A)","1.03A","5a7mB-3jbbB:undetectable","5a7mA-3jbbB:11.59"],["5DZK_R_BEZR801_1","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"SER A 272;ALA A 271;LEU A 264;LEU A 261","CYC A1521 ( 3.7A);None;None;None","1.05A","5dzkd-2veaA:undetectable;5dzkr-2veaA:undetectable","5a7mB-3jbbB:11.59"],["5EB5_B_010B607_0","HNL ISOENZYME 5","4rmp","ALLOPHYCOCYANIN","Phormidium rubidum",5,"ALA A 129;ALA A 125;VAL A  65;LEU A  82;VAL A  66","CYC A 201 ( 3.7A);CYC A 201 (-3.4A);CYC A 201 (-4.1A);None;None","1.44A","5eb5B-4rmpA:undetectable","5dzkd-2veaA:18.41;5dzkr-2veaA:3.28"],["5ESJ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3w2z","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Nostoc sp. PCC 7120",4,"TYR A  59;ILE A 137;GLY A 101;THR A  98","CYC A 201 (-4.0A);CYC A 201 (-4.7A);None;None","0.93A","5esjA-3w2zA:undetectable","5eb5B-4rmpA:14.31"],["5HS1_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3w2z","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Nostoc sp. PCC 7120",4,"TYR A  59;ILE A 137;GLY A 101;THR A  98","CYC A 201 (-4.0A);CYC A 201 (-4.7A);None;None","0.88A","5hs1A-3w2zA:undetectable","5esjA-3w2zA:14.07"],["5JI0_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","5tou","PHYCOCYANIN BETA-1 SUBUNIT","Pseudanabaena sp. lw0831",5,"ILE D 131;LEU D  90;ALA D  55;CYH D 109;LEU D 105","None;None;None;CYC D 202 ( 3.9A);None","1.24A","5ji0A-5touD:undetectable","5hs1A-3w2zA:14.34"],["5KOX_A_RFPA502_2","PENTACHLOROPHENOL 4-MONOOXYGENASE","3w2z","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Nostoc sp. PCC 7120",3,"VAL A  23;ARG A 102;PRO A 139","None;CYC A 201 (-3.7A);None","0.86A","5koxA-3w2zA:undetectable","5ji0A-5touD:21.22"],["5LSU_A_SAMA1304_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"ASN B  63;CYH B  75;ARG B  80;CYH B  84;LEU B  66","None;CYC B 175 (-3.5A);CYC B 175 (-3.9A);CYC B 175 (-1.8A);CYC B 175 ( 4.8A)","1.42A","5lsuA-1liaB:undetectable","5koxA-3w2zA:19.44"],["5LSU_A_SAMA1304_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",5,"GLY B 123;ASN B  63;CYH B  75;CYH B  84;LEU B  66","None;None;CYC B 175 (-3.5A);CYC B 175 (-1.8A);CYC B 175 ( 4.8A)","1.27A","5lsuA-1liaB:undetectable","5lsuA-1liaB:21.01"],["5LSU_A_SAMA1304_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","4lms","CRYPTOPHYTE PHYCOCYANIN (BETA CHAIN)","Chroomonas sp.",5,"ASN B  63;CYH B  73;ARG B  78;CYH B  82;LEU B  66","None;CYC B 203 (-3.6A);None;CYC B 203 (-1.8A);CYC B 203 ( 4.8A)","1.34A","5lsuA-4lmsB:undetectable","5lsuA-1liaB:21.01"],["5LSU_A_SAMA1304_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","4lms","CRYPTOPHYTE PHYCOCYANIN (BETA CHAIN)","Chroomonas sp.",5,"GLY B 121;ASN B  63;CYH B  73;CYH B  82;LEU B  66","MEN B  72 ( 4.6A);None;CYC B 203 (-3.6A);CYC B 203 (-1.8A);CYC B 203 ( 4.8A)","1.34A","5lsuA-4lmsB:undetectable","5lsuA-4lmsB:20.45"],["5MZJ_A_TEPA2401_1","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","3mwn","PHYCOERYTHRIN","Phormidium tenue",4,"LEU A1138;MET A1144;LEU A1044;ILE A1093","CYC A3002 (-4.0A);None;CYC A3002 (-3.9A);None","0.98A","5mzjA-3mwnA:undetectable","5lsuA-4lmsB:20.45"],["5UMW_B_RBFB201_1","GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE;GLYOXALASE\/BLEOMYCIN RESISANCE PROTEIN\/DIOXYGENASE","1lia","R-PHYCOERYTHRIN","Polysiphonia urceolata",4,"VAL A  52;ARG A  93;TYR B  18;LEU A 107","None;CYC A 175 ( 4.9A);None;None","1.01A","5umwB-1liaA:undetectable;5umwE-1liaA:undetectable","5mzjA-3mwnA:15.57"],["5VCV_A_1N1A404_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","3mwn","PHYCOERYTHRIN","Phormidium tenue",4,"VAL A1051;LEU A1156;CYH A1153;ASP A1143","CYC A3002 ( 4.5A);None;None;CYC A3002 ( 3.8A)","1.29A","5vcvA-3mwnA:undetectable","5umwB-1liaA:18.90;5umwE-1liaA:18.90"],["6A7J_A_TESA502_0","CYTOCHROME P450","2vml","PHYCOCYANIN ALPHA CHAIN","Gloeobacter violaceus",4,"LEU A  19;LEU A  24;ALA A  26;ALA A  27","None;CYC B1153 (-4.1A);None;None","0.75A","6a7jA-2vmlA:undetectable","5vcvA-3mwnA:21.32"],["6D8P_B_ACTB804_0","UNCHARACTERIZED PROTEIN","2vea","PHYTOCHROME-LIKE PROTEIN CPH1","Synechocystis sp. PCC 6803",4,"HIS A 260;VAL A 227;LEU A 264;ALA A 256","CYC A1521 (-3.4A);None;None;CYC A1521 (-3.9A)","1.29A","6d8pB-2veaA:undetectable","6a7jA-2vmlA:21.02"],["6GNF_C_QPSC602_1","-","4po5","ALLOPHYCOCYANIN SUBUNIT ALPHA-B","Synechocystis sp. PCC 6803",5,"THR A 106;GLY A 108;LEU A 109;SER A   2;VAL A 130","None;CYC A 201 ( 4.4A);None;None;None","1.25A","6gnfC-4po5A:undetectable","6d8pB-2veaA:22.02"],["6JMJ_A_ASCA201_0","PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE","4f0u","ALLOPHYCOCYANIN, BETA SUBUNIT","Synechococcus elongatus",4,"GLY B 127;THR B 129;SER B 171;SER B 170","None;CYC B 201 (-4.2A);None;None","1.12A","6jmjA-4f0uB:undetectable","6gnfC-4po5A:13.79"],["6MKE_D_FK5D201_1","PEPTIDYLPROLYL ISOMERASE","4bwi","PHYTOCHROME-LIKE PROTEIN CPH2","Synechocystis sp.",5,"TYR A 133;ASP A  79;ARG A 383;VAL A 139;ILE A 156","CYC A1422 (-4.1A);CYC A1422 (-4.0A);None;None;CYC A1422 ( 4.7A)","1.45A","6mkeD-4bwiA:undetectable","6jmjA-4f0uB:24.46"]]