SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CXY'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	1wvg	CDP-GLUCOSE 4,6-DEHYDRATASE (Salmonella enterica)	3 / 3	LYS A 136 ASP A 203 ASN A 197	CXY A 401 (-2.8A) None CXY A 401 (-2.9A)	1.18A	2bm9A-1wvgA: 4.8	2bm9A-1wvgA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_A_SAMA400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	1wvg	CDP-GLUCOSE 4,6-DEHYDRATASE (Salmonella enterica)	3 / 3	ASN A 197 ARG A 232 ASP A 157	CXY A 401 (-2.9A) CXY A 401 (-3.5A) None	0.87A	2qe6A-1wvgA: undetectable	2qe6A-1wvgA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_B_SAMB400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	1wvg	CDP-GLUCOSE 4,6-DEHYDRATASE (Salmonella enterica)	3 / 3	ASN A 197 ARG A 232 ASP A 157	CXY A 401 (-2.9A) CXY A 401 (-3.5A) None	0.92A	2qe6B-1wvgA: undetectable	2qe6B-1wvgA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_2 (CYTOCHROME P450 3A4)	1wvg	CDP-GLUCOSE 4,6-DEHYDRATASE (Salmonella enterica)	3 / 3	ARG A 208 ARG A 232 ARG A 96	APR A 400 ( 2.6A) CXY A 401 (-3.5A) None	0.96A	5vcgA-1wvgA: undetectable	5vcgA-1wvgA: 22.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BM9_A_SAMA301_1","CEPHALOSPORIN HYDROXYLASE CMCI","1wvg","CDP-GLUCOSE 4,6-DEHYDRATASE","Salmonella enterica",3,"LYS A 136;ASP A 203;ASN A 197","CXY A 401 (-2.8A);None;CXY A 401 (-2.9A)","1.18A","2bm9A-1wvgA:4.8",null],["2QE6_A_SAMA400_1","UNCHARACTERIZED PROTEIN TFU_2867","1wvg","CDP-GLUCOSE 4,6-DEHYDRATASE","Salmonella enterica",3,"ASN A 197;ARG A 232;ASP A 157","CXY A 401 (-2.9A);CXY A 401 (-3.5A);None","0.87A","2qe6A-1wvgA:undetectable","2bm9A-1wvgA:17.84"],["2QE6_B_SAMB400_1","UNCHARACTERIZED PROTEIN TFU_2867","1wvg","CDP-GLUCOSE 4,6-DEHYDRATASE","Salmonella enterica",3,"ASN A 197;ARG A 232;ASP A 157","CXY A 401 (-2.9A);CXY A 401 (-3.5A);None","0.92A","2qe6B-1wvgA:undetectable","2qe6A-1wvgA:21.74"],["5VCG_A_08YA602_2","CYTOCHROME P450 3A4","1wvg","CDP-GLUCOSE 4,6-DEHYDRATASE","Salmonella enterica",3,"ARG A 208;ARG A 232;ARG A  96","APR A 400 ( 2.6A);CXY A 401 (-3.5A);None","0.96A","5vcgA-1wvgA:undetectable","2qe6B-1wvgA:21.74"]]