SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CXM'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZZ_A_SAMA635_0 (ACLACINOMYCIN-10-HYD ROXYLASE)	3m6x	RRNA METHYLASE (Thermus thermophilus)	5 / 12	GLY A 184 GLY A 291 LEU A 25 PRO A 284 PHE A 186	None None None None CXM A 1 ( 4.9A)	1.12A	1qzzA-3m6xA: 12.1	1qzzA-3m6xA: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_2 (ESTROGEN-RELATED RECEPTOR GAMMA)	1nkz	LIGHT-HARVESTING PROTEIN B-800/850, ALPHA CHAIN LIGHT-HARVESTING PROTEIN B-800/850, BETA CHAIN (Rhodoblastus acidophilus)	3 / 3	LEU A 19 HIS B 12 ILE A 6	None CXM A 1 ( 4.0A) BCL A 307 ( 4.1A)	0.62A	1s9pB-1nkzA: undetectable	1s9pB-1nkzA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDS_A_SAMA5635_0 (PROTEIN RDMB)	3m6x	RRNA METHYLASE (Thermus thermophilus)	5 / 12	GLY A 184 GLY A 291 LEU A 25 PRO A 284 PHE A 186	None None None None CXM A 1 ( 4.9A)	1.12A	1xdsA-3m6xA: 10.5	1xdsA-3m6xA: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDS_B_SAMB9635_0 (PROTEIN RDMB)	3m6x	RRNA METHYLASE (Thermus thermophilus)	5 / 12	GLY A 184 GLY A 291 LEU A 25 PRO A 284 PHE A 186	None None None None CXM A 1 ( 4.9A)	1.14A	1xdsB-3m6xA: 10.8	1xdsB-3m6xA: 24.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QZZ_A_SAMA635_0","ACLACINOMYCIN-10-HYDROXYLASE","3m6x","RRNA METHYLASE","Thermus thermophilus",5,"GLY A 184;GLY A 291;LEU A  25;PRO A 284;PHE A 186","None;None;None;None;CXM A   1 ( 4.9A)","1.12A","1qzzA-3m6xA:12.1",null],["1S9P_B_DESB459_2","ESTROGEN-RELATED RECEPTOR GAMMA","1nkz","LIGHT-HARVESTING PROTEIN B-800\/850, ALPHA CHAIN;LIGHT-HARVESTING PROTEIN B-800\/850, BETA CHAIN","Rhodoblastus acidophilus",3,"LEU A  19;HIS B  12;ILE A   6","None;CXM A   1 ( 4.0A);BCL A 307 ( 4.1A)","0.62A","1s9pB-1nkzA:undetectable","1qzzA-3m6xA:24.12"],["1XDS_A_SAMA5635_0","PROTEIN RDMB","3m6x","RRNA METHYLASE","Thermus thermophilus",5,"GLY A 184;GLY A 291;LEU A  25;PRO A 284;PHE A 186","None;None;None;None;CXM A   1 ( 4.9A)","1.12A","1xdsA-3m6xA:10.5","1s9pB-1nkzA:13.22"],["1XDS_B_SAMB9635_0","PROTEIN RDMB","3m6x","RRNA METHYLASE","Thermus thermophilus",5,"GLY A 184;GLY A 291;LEU A  25;PRO A 284;PHE A 186","None;None;None;None;CXM A   1 ( 4.9A)","1.14A","1xdsB-3m6xA:10.8","1xdsA-3m6xA:24.12"]]