SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CVV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 6b73 SOLUBLE CYTOCHROME
B562, KAPPA-TYPE
OPIOID RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 12 TYR A 320
ALA A 104
GLY A  76
THR A 111
ASN A 326
 CVV  A2001 (-3.8A)
None
None
CVV  A2001 ( 4.3A)
None
 1.13A 2okcA-6b73A:
undetectable		 2okcA-6b73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 6b73 SOLUBLE CYTOCHROME
B562, KAPPA-TYPE
OPIOID RECEPTOR
(Escherichia
coli;
Homo
sapiens) 		5 / 11 PHE A 283
HIS A 291
PHE A 235
MET A 142
GLY A 319
 None
CVV  A2001 ( 4.5A)
None
CVV  A2001 (-3.6A)
CVV  A2001 (-3.7A)
 1.36A 4qa0B-6b73A:
undetectable		 4qa0B-6b73A:
13.71