SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CV7'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
LEU A 848
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.59A 1a28A-4udbA:
36.0		 1a28A-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.52A 1a28A-4udbA:
36.0		 1a28A-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 848
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.64A 1a28B-4udbA:
35.4		 1a28B-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.53A 1a28B-4udbA:
35.4		 1a28B-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
MET A 852
 CV7  A1987 ( 4.5A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.6A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
 1.41A 1a28B-4udbA:
35.4		 1a28B-4udbA:
54.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.47A 1errB-4udbA:
23.9		 1errB-4udbA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 769
LEU A 772
ALA A 773
LEU A 810
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.45A 1g50A-4udbA:
27.1		 1g50A-4udbA:
28.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.7A)
 0.77A 1gs4A-4udbA:
34.0		 1gs4A-4udbA:
52.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 10 LEU A 769
LEU A 772
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.37A 1gwrA-4udbA:
27.9		 1gwrA-4udbA:
26.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
THR A 945
PHE A 956
LEU A 960
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
None
 0.44A 1m2zA-4udbA:
34.6		 1m2zA-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
LEU A 960
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
None
 0.68A 1m2zA-4udbA:
34.6		 1m2zA-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
CYH A 942
THR A 945
PHE A 956
LEU A 960
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
None
 1.10A 1m2zA-4udbA:
34.6		 1m2zA-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 942
THR A 945
PHE A 956
LEU A 960
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
None
 0.39A 1m2zD-4udbA:
34.3		 1m2zD-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.74A 1m2zD-4udbA:
34.3		 1m2zD-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
LEU A 960
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
None
 1.22A 1m2zD-4udbA:
34.3		 1m2zD-4udbA:
52.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
GLN A 776
LEU A 814
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.61A 1nhzA-4udbA:
28.7		 1nhzA-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
THR A 945
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
 0.82A 1p93A-4udbA:
33.4		 1p93A-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.61A 1p93B-4udbA:
33.6		 1p93B-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.05A 1p93B-4udbA:
33.6		 1p93B-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.79A 1p93C-4udbA:
33.4		 1p93C-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 852
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.76A 1p93D-4udbA:
33.3		 1p93D-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.05A 1p93D-4udbA:
33.3		 1p93D-4udbA:
51.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.36A 1pcgA-4udbA:
27.0		 1pcgA-4udbA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.39A 1pcgB-4udbA:
27.2		 1pcgB-4udbA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ALA A 773
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.48A 1qknA-4udbA:
24.7		 1qknA-4udbA:
29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.26A 1qktA-4udbA:
24.3		 1qktA-4udbA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ALA A 773
MET A 807
LEU A 810
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.59A 1s9pA-4udbA:
25.5		 1s9pA-4udbA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 772
ALA A 773
MET A 807
LEU A 810
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.66A 1s9pB-4udbA:
26.1		 1s9pB-4udbA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
LEU A 769
LEU A 772
ALA A 773
MET A 807
LEU A 810
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.58A 1s9pC-4udbA:
25.9		 1s9pC-4udbA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ALA A 773
MET A 807
LEU A 810
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.58A 1s9pD-4udbA:
27.5		 1s9pD-4udbA:
25.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
MET A 807
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 0.76A 1sqnA-4udbA:
35.8		 1sqnA-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
MET A 852
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
 0.49A 1sqnA-4udbA:
35.8		 1sqnA-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
MET A 852
 CV7  A1987 ( 4.5A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.6A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
 1.29A 1sqnA-4udbA:
35.8		 1sqnA-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
GLN A 776
MET A 807
LEU A 848
LEU A 938
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.4A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.71A 1sqnB-4udbA:
35.1		 1sqnB-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
MET A 852
LEU A 938
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.55A 1sqnB-4udbA:
35.1		 1sqnB-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
MET A 852
LEU A 827
 CV7  A1987 ( 4.5A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.6A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
None
 1.27A 1sqnB-4udbA:
35.1		 1sqnB-4udbA:
52.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 PHE A 829
LEU A 938
PHE A 835
MET A 840
 CV7  A1987 (-4.9A)
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 3.7A)
 1.36A 1wrkB-4udbA:
undetectable		 1wrkB-4udbA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 PHE A 829
LEU A 938
PHE A 835
MET A 840
 CV7  A1987 (-4.9A)
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 3.7A)
 1.23A 1wrlC-4udbA:
undetectable		 1wrlC-4udbA:
16.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.37A 1ya3A-4udbA:
37.2		 1ya3A-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 4 LEU A 769
LEU A 810
SER A 811
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 (-4.0A)
None
CV7  A1987 ( 3.9A)
 0.41A 1ya3A-4udbA:
37.2		 1ya3A-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
SER A 811
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.57A 1ya3B-4udbA:
36.8		 1ya3B-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 1.23A 1ya3B-4udbA:
36.8		 1ya3B-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		3 / 3 LEU A 769
LEU A 810
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 3.7A)
 0.23A 1ya3B-4udbA:
36.8		 1ya3B-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.44A 1ya3C-4udbA:
36.3		 1ya3C-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
None
 0.67A 1z95A-4udbA:
33.4		 1z95A-4udbA:
48.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 10 LEU A 766
ASN A 770
GLN A 776
LEU A 814
ARG A 817
LEU A 848
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.72A 1zucA-4udbA:
36.0		 1zucA-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 10 LEU A 766
ASN A 770
LEU A 827
LEU A 848
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.4A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.28A 1zucA-4udbA:
36.0		 1zucA-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 848
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.64A 1zucB-4udbA:
35.0		 1zucB-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 848
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.4A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.30A 1zucB-4udbA:
35.0		 1zucB-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.57A 1zucB-4udbA:
35.0		 1zucB-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 827
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.17A 1zucB-4udbA:
35.0		 1zucB-4udbA:
54.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.37A 2aa5A-4udbA:
36.6		 2aa5A-4udbA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.33A 2aa5B-4udbA:
36.5		 2aa5B-4udbA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 1.25A 2aa5B-4udbA:
36.5		 2aa5B-4udbA:
90.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
THR A 945
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.26A 2aa6A-4udbA:
36.7		 2aa6A-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.29A 2aa6B-4udbA:
36.6		 2aa6B-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
LEU A 827
MET A 852
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 1.40A 2aa6B-4udbA:
36.6		 2aa6B-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 852
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.35A 2ab2A-4udbA:
36.6		 2ab2A-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 6 LEU A 769
LEU A 772
LEU A 810
LEU A 814
CYH A 849
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.9A)
 0.58A 2ab2A-4udbA:
36.6		 2ab2A-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
PHE A 829
MET A 852
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.36A 2ab2B-4udbA:
36.4		 2ab2B-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 5 LEU A 769
LEU A 772
LEU A 810
LEU A 814
CYH A 849
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 4.2A)
 0.64A 2ab2B-4udbA:
36.4		 2ab2B-4udbA:
91.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
LEU A 772
TRP A 806
MET A 807
ARG A 817
LEU A 938
 CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
 0.68A 2am9A-4udbA:
34.0		 2am9A-4udbA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
LEU A 938
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
 0.93A 2am9A-4udbA:
34.0		 2am9A-4udbA:
49.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.46A 2j7xA-4udbA:
27.5		 2j7xA-4udbA:
29.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.52A 2jfaA-4udbA:
24.8		 2jfaA-4udbA:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.55A 2jfaB-4udbA:
23.8		 2jfaB-4udbA:
26.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.46A 2oaxA-4udbA:
36.3		 2oaxA-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.15A 2oaxA-4udbA:
36.3		 2oaxA-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
ALA A 773
TRP A 806
LEU A 810
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
 0.28A 2oaxA-4udbA:
36.3		 2oaxA-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.41A 2oaxB-4udbA:
35.7		 2oaxB-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.18A 2oaxB-4udbA:
35.7		 2oaxB-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
LEU A 938
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.44A 2oaxC-4udbA:
35.8		 2oaxC-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.18A 2oaxC-4udbA:
35.8		 2oaxC-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
LEU A 938
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.7A)
 0.42A 2oaxD-4udbA:
36.8		 2oaxD-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.7A)
 1.29A 2oaxD-4udbA:
36.8		 2oaxD-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
LEU A 810
CYH A 942
THR A 945
 CV7  A1987 (-4.1A)
CV7  A1987 (-4.0A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.47A 2oaxD-4udbA:
36.8		 2oaxD-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.7A)
 0.48A 2oaxE-4udbA:
35.9		 2oaxE-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
CYH A 942
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.7A)
 1.23A 2oaxE-4udbA:
35.9		 2oaxE-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		12 / 12 ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.50A 2oaxF-4udbA:
36.0		 2oaxF-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
LEU A 827
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.16A 2oaxF-4udbA:
36.0		 2oaxF-4udbA:
91.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
ARG A 817
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.7A)
 0.74A 2oz7A-4udbA:
33.0		 2oz7A-4udbA:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 LEU A 766
TRP A 806
MET A 807
LEU A 938
 CV7  A1987 (-3.6A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 3.9A)
 1.35A 2oz7A-4udbA:
33.0		 2oz7A-4udbA:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 6 TRP A 806
MET A 807
MET A 852
LEU A 938
 None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 1.25A 2oz7A-4udbA:
33.0		 2oz7A-4udbA:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.67A 2q7iA-4udbA:
33.9		 2q7iA-4udbA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.73A 2q7jA-4udbA:
34.0		 2q7jA-4udbA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
 0.70A 2q7kA-4udbA:
33.8		 2q7kA-4udbA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.69A 2q7lA-4udbA:
33.9		 2q7lA-4udbA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.47A 2qxsA-4udbA:
24.3		 2qxsA-4udbA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.49A 2qxsB-4udbA:
24.2		 2qxsB-4udbA:
26.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.0A)
 0.50A 2w8yA-4udbA:
35.2		 2w8yA-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
TRP A 806
MET A 807
ARG A 817
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 0.79A 2w8yA-4udbA:
35.2		 2w8yA-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
ASN A 770
MET A 807
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 0.83A 2w8yB-4udbA:
35.7		 2w8yB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
 0.52A 2w8yB-4udbA:
35.7		 2w8yB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
MET A 852
 CV7  A1987 ( 4.5A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.6A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
 1.27A 2w8yB-4udbA:
35.7		 2w8yB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.70A 2yhdA-4udbA:
33.9		 2yhdA-4udbA:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
LEU A 772
MET A 807
ARG A 817
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.7A)
 0.74A 2yloA-4udbA:
33.8		 2yloA-4udbA:
49.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 11 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
LEU A 938
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
 0.72A 2ylpA-4udbA:
34.0		 2ylpA-4udbA:
49.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 11 LEU A 766
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.70A 2ylqA-4udbA:
34.0		 2ylqA-4udbA:
49.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
CYH A 849
LEU A 938
CYH A 942
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.62A 3cldA-4udbA:
34.4		 3cldA-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.43A 3cldA-4udbA:
34.4		 3cldA-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.23A 3cldA-4udbA:
34.4		 3cldA-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
LEU A 938
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
 0.71A 3cldB-4udbA:
34.5		 3cldB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.47A 3cldB-4udbA:
34.5		 3cldB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.95A 3cldB-4udbA:
34.5		 3cldB-4udbA:
52.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
ASN A 770
MET A 807
ARG A 817
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 0.82A 3d90A-4udbA:
35.5		 3d90A-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
 0.59A 3d90A-4udbA:
35.5		 3d90A-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
LEU A 769
LEU A 766
LEU A 814
MET A 852
 CV7  A1987 ( 4.5A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.6A)
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
 1.27A 3d90A-4udbA:
35.5		 3d90A-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 0.69A 3d90B-4udbA:
34.8		 3d90B-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
 0.69A 3d90B-4udbA:
34.8		 3d90B-4udbA:
52.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 827
LEU A 848
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.0A)
 1.47A 3d90B-4udbA:
34.8		 3d90B-4udbA:
52.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.32A 3erdA-4udbA:
27.6		 3erdA-4udbA:
27.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
VAL A 954
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
None
 0.63A 3gn8A-4udbA:
35.5		 3gn8A-4udbA:
57.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
THR A 945
VAL A 954
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
None
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.7A)
 1.15A 3gn8B-4udbA:
35.4		 3gn8B-4udbA:
57.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
CYH A 942
THR A 945
VAL A 954
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.7A)
 0.61A 3gn8B-4udbA:
35.4		 3gn8B-4udbA:
57.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
GLN A 776
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.82A 3h52A-4udbA:
24.9		 3h52A-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
GLN A 776
MET A 807
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.74A 3h52A-4udbA:
24.9		 3h52A-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 772
TRP A 806
MET A 807
MET A 959
LEU A 960
 CV7  A1987 ( 4.5A)
None
CV7  A1987 ( 3.9A)
None
None
 1.41A 3h52B-4udbA:
27.5		 3h52B-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
LEU A 814
ARG A 817
CYH A 849
MET A 852
 CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
 0.79A 3h52B-4udbA:
27.5		 3h52B-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 GLY A 774
GLN A 776
LEU A 814
ARG A 817
MET A 852
CYH A 942
ILE A 963
 None
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.0A)
None
 0.89A 3h52B-4udbA:
27.5		 3h52B-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 814
ARG A 817
CYH A 849
MET A 852
ILE A 964
 CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
None
 0.94A 3h52B-4udbA:
27.5		 3h52B-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
PHE A 829
MET A 852
 CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
 0.62A 3h52C-4udbA:
25.5		 3h52C-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
GLN A 776
TRP A 806
PHE A 829
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
 1.00A 3h52C-4udbA:
25.5		 3h52C-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
 CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.81A 3h52D-4udbA:
26.9		 3h52D-4udbA:
55.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.68A 3h52D-4udbA:
26.9		 3h52D-4udbA:
55.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.48A 3hm1A-4udbA:
28.2		 3hm1A-4udbA:
27.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
LEU A 938
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.26A 3mneA-4udbA:
34.4		 3mneA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
LEU A 938
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
 0.70A 3mneA-4udbA:
34.4		 3mneA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.27A 3mneA-4udbA:
34.4		 3mneA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.29A 3mnoA-4udbA:
34.9		 3mnoA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
MET A 807
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.11A 3mnoA-4udbA:
34.9		 3mnoA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.90A 3mnoA-4udbA:
34.9		 3mnoA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.33A 3mnpA-4udbA:
35.1		 3mnpA-4udbA:
53.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
MET A 807
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.12A 3mnpA-4udbA:
35.1		 3mnpA-4udbA:
53.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
MET A 807
ARG A 817
MET A 852
LEU A 938
 CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.96A 3mnpA-4udbA:
35.1		 3mnpA-4udbA:
53.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
LEU A 772
MET A 807
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.38A 3ollA-4udbA:
27.3		 3ollA-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
ALA A 773
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.47A 3olsA-4udbA:
28.1		 3olsA-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ALA A 773
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.47A 3olsB-4udbA:
27.4		 3olsB-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.36A 3q95A-4udbA:
28.0		 3q95A-4udbA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
ALA A 773
LEU A 810
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.33A 3q95B-4udbA:
27.0		 3q95B-4udbA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.29A 3uudA-4udbA:
28.0		 3uudA-4udbA:
27.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		11 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
LEU A 814
ARG A 817
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.32A 3vhuA-4udbA:
37.4		 3vhuA-4udbA:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 766
ASN A 770
LEU A 827
LEU A 938
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.19A 3vhuA-4udbA:
37.4		 3vhuA-4udbA:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU A 769
LEU A 772
LEU A 810
SER A 811
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-4.0A)
None
 0.18A 3vhuA-4udbA:
37.4		 3vhuA-4udbA:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
MET A 807
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.73A 3zqtA-4udbA:
34.0		 3zqtA-4udbA:
49.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 766
LEU A 772
GLN A 776
MET A 807
ARG A 817
 CV7  A1987 (-3.6A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.88A 3zqtA-4udbA:
34.0		 3zqtA-4udbA:
49.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
CYH A 942
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
 0.42A 4fn9A-4udbA:
35.7		 4fn9A-4udbA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
 0.46A 4fn9B-4udbA:
36.0		 4fn9B-4udbA:
68.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.75A 4hlwA-4udbA:
33.7		 4hlwA-4udbA:
49.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.44A 4j24A-4udbA:
28.1		 4j24A-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
MET A 807
LEU A 810
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.7A)
 0.47A 4j24B-4udbA:
27.9		 4j24B-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.45A 4j24C-4udbA:
28.0		 4j24C-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
MET A 807
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.37A 4j24D-4udbA:
27.7		 4j24D-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.51A 4j26A-4udbA:
27.5		 4j26A-4udbA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.51A 4j26B-4udbA:
27.7		 4j26B-4udbA:
27.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 9 LEU A 766
LEU A 848
PHE A 941
TYR A 944
THR A 945
LEU A 952
 CV7  A1987 (-3.6A)
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.6A)
None
CV7  A1987 (-3.1A)
None
 0.51A 4ltwA-4udbA:
36.1		 4ltwA-4udbA:
65.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
LEU A 769
ASN A 770
LEU A 772
ALA A 773
GLN A 776
MET A 807
ARG A 817
LEU A 938
CYH A 942
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.40A 4ltwA-4udbA:
36.1		 4ltwA-4udbA:
65.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 8 TRP A 806
MET A 852
PHE A 941
THR A 945
VAL A 954
PHE A 956
 None
CV7  A1987 ( 3.7A)
CV7  A1987 (-4.6A)
CV7  A1987 (-3.1A)
None
CV7  A1987 ( 4.7A)
 0.48A 4ltwA-4udbA:
36.1		 4ltwA-4udbA:
65.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 7 ASN A 770
LEU A 938
ILE A 963
ILE A 964
 CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
None
None
 0.60A 4ojbA-4udbA:
33.3		 4ojbA-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
None
 0.82A 4ok1A-4udbA:
33.2		 4ok1A-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 8 LEU A 766
ASN A 770
LEU A 938
ILE A 963
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
None
 0.64A 4ok1A-4udbA:
33.2		 4ok1A-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		4 / 8 LEU A 766
MET A 852
LEU A 938
ILE A 963
 CV7  A1987 (-3.6A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
None
 0.89A 4ok1A-4udbA:
33.2		 4ok1A-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
None
 0.81A 4okbA-4udbA:
33.1		 4okbA-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
MET A 852
ILE A 964
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
None
 0.82A 4oktA-4udbA:
33.1		 4oktA-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
GLN A 776
MET A 807
ARG A 817
ILE A 964
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
None
 0.69A 4okwA-4udbA:
33.2		 4okwA-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 769
LEU A 772
GLN A 776
MET A 807
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
 0.66A 4olmA-4udbA:
33.0		 4olmA-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.47A 4p6xA-4udbA:
34.4		 4p6xA-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 11 ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
 0.39A 4p6xC-4udbA:
34.9		 4p6xC-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.38A 4p6xE-4udbA:
34.3		 4p6xE-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 852
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
 0.66A 4p6xG-4udbA:
34.7		 4p6xG-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.36A 4p6xG-4udbA:
34.7		 4p6xG-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.09A 4p6xG-4udbA:
34.7		 4p6xG-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.34A 4p6xI-4udbA:
34.5		 4p6xI-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.67A 4p6xI-4udbA:
34.5		 4p6xI-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.72A 4p6xK-4udbA:
34.8		 4p6xK-4udbA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.12A 4p6xK-4udbA:
34.8		 4p6xK-4udbA:
54.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
LEU A 772
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.28A 4pxmA-4udbA:
27.8		 4pxmA-4udbA:
27.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		10 / 12 LEU A 766
ASN A 770
ALA A 773
GLN A 776
MET A 807
ARG A 817
MET A 852
LEU A 938
CYH A 942
PHE A 956
 CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.7A)
 0.26A 4udaA-4udbA:
38.5		 4udaA-4udbA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 6 LEU A 765
LEU A 848
PHE A 941
THR A 945
VAL A 954
 None
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.6A)
CV7  A1987 (-3.1A)
None
 0.95A 4udaA-4udbA:
38.5		 4udaA-4udbA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 6 LEU A 769
TRP A 806
LEU A 848
PHE A 941
THR A 945
VAL A 954
 CV7  A1987 (-4.1A)
None
CV7  A1987 ( 4.4A)
CV7  A1987 (-4.6A)
CV7  A1987 (-3.1A)
None
 0.32A 4udaA-4udbA:
38.5		 4udaA-4udbA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 ASN A 770
GLY A 774
GLN A 776
TRP A 806
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.28A 4udcA-4udbA:
35.2		 4udcA-4udbA:
51.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 769
ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
THR A 945
PHE A 956
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.64A 4udcA-4udbA:
35.2		 4udcA-4udbA:
51.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.58A 4xi3B-4udbA:
24.7		 4xi3B-4udbA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 772
ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.61A 4xi3C-4udbA:
24.4		 4xi3C-4udbA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA A 773
TRP A 806
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-3.5A)
None
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.62A 4xi3D-4udbA:
24.2		 4xi3D-4udbA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 12 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
LEU A 960
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
None
 0.57A 4zn7A-4udbA:
27.6		 4zn7A-4udbA:
27.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6O_A_4YHA501_1
(BH2163 PROTEIN)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 9 ASN A 770
MET A 845
MET A 840
PHE A 835
GLN A 842
 CV7  A1987 (-3.1A)
CV7  A1987 (-4.6A)
CV7  A1987 ( 3.7A)
None
None
 1.34A 5c6oA-4udbA:
2.1		 5c6oA-4udbA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.26A 5dxeB-4udbA:
27.9		 5dxeB-4udbA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 772
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.27A 5dxgB-4udbA:
27.9		 5dxgB-4udbA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.39A 5gtrA-4udbA:
26.7		 5gtrA-4udbA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 769
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.37A 5hyrA-4udbA:
27.9		 5hyrA-4udbA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 11 LEU A 772
ALA A 773
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.29A 5hyrB-4udbA:
27.4		 5hyrB-4udbA:
27.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ALA A 773
TRP A 806
MET A 807
SER A 811
LEU A 814
MET A 852
LEU A 938
 CV7  A1987 (-3.5A)
None
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
 0.72A 5mwyA-4udbA:
37.6		 5mwyA-4udbA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		9 / 12 LEU A 766
LEU A 769
ASN A 770
ALA A 773
TRP A 806
MET A 807
SER A 811
LEU A 814
LEU A 938
 CV7  A1987 (-3.6A)
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.5A)
None
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 4.0A)
CV7  A1987 ( 3.9A)
 0.33A 5mwyA-4udbA:
37.6		 5mwyA-4udbA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		6 / 6 GLN A 776
ARG A 817
PHE A 829
CYH A 942
THR A 945
PHE A 956
 CV7  A1987 (-3.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 (-4.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.26A 5mwyA-4udbA:
37.6		 5mwyA-4udbA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
CYH A 849
MET A 852
THR A 945
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
 0.55A 5nfpA-4udbA:
35.3		 5nfpA-4udbA:
51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 ASN A 770
GLN A 776
MET A 807
ARG A 817
MET A 852
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 0.57A 5nfpA-4udbA:
35.3		 5nfpA-4udbA:
51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
 CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
 1.32A 5nfpA-4udbA:
35.3		 5nfpA-4udbA:
51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 GLN A 776
ARG A 817
MET A 840
CYH A 849
MET A 852
 CV7  A1987 (-3.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
 0.91A 5nfpA-4udbA:
35.3		 5nfpA-4udbA:
51.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
ALA A 773
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.42A 5toaA-4udbA:
25.9		 5toaA-4udbA:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 772
MET A 807
LEU A 810
LEU A 814
ARG A 817
 CV7  A1987 ( 4.5A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
 0.47A 5toaB-4udbA:
25.5		 5toaB-4udbA:
27.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLN A 776
LEU A 814
ARG A 817
CYH A 849
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
 0.72A 5uc1A-4udbA:
22.4		 5uc1A-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLY A 774
GLN A 776
LEU A 814
ARG A 817
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
None
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
 0.71A 5uc1A-4udbA:
22.4		 5uc1A-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 772
GLN A 776
TRP A 806
LEU A 814
ARG A 817
CYH A 849
MET A 852
 CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
 0.68A 5uc1A-4udbA:
22.4		 5uc1A-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 772
GLY A 774
GLN A 776
TRP A 806
LEU A 814
ARG A 817
MET A 852
 CV7  A1987 ( 4.5A)
None
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
 0.87A 5uc1A-4udbA:
22.4		 5uc1A-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
ASN A 770
LEU A 772
GLY A 774
GLN A 776
LEU A 814
ARG A 817
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
None
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
 0.77A 5uc1B-4udbA:
22.5		 5uc1B-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		7 / 12 LEU A 769
LEU A 772
GLN A 776
LEU A 814
ARG A 817
CYH A 849
MET A 852
 CV7  A1987 (-4.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 4.2A)
CV7  A1987 ( 3.7A)
 0.73A 5uc1B-4udbA:
22.5		 5uc1B-4udbA:
47.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 ASN A 770
GLN A 776
TRP A 806
ARG A 817
PHE A 829
MET A 852
LEU A 938
CYH A 942
 CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.72A 5uc3A-4udbA:
29.7		 5uc3A-4udbA:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens) 		8 / 12 LEU A 769
GLN A 776
TRP A 806
ARG A 817
PHE A 829
MET A 852
LEU A 938
CYH A 942
 CV7  A1987 (-4.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 (-3.7A)
CV7  A1987 (-4.9A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
CV7  A1987 (-4.0A)
 0.58A 5uc3B-4udbA:
29.3		 5uc3B-4udbA:
48.94