SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CUK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.98A 1azmA-3sbqA:
undetectable		 1azmA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.99A 1bzmA-3sbqA:
undetectable		 1bzmA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 6 HIS A 130
HIS A 178
HIS A 326
HIS A 382
HIS A 433
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.1A)
CUK  A 702 ( 3.3A)
CUK  A 702 (-3.1A)
 1.33A 1fweC-3sbqA:
undetectable		 1fweC-3sbqA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 GLU A 492
HIS A 494
HIS A  78
 None
CUK  A 702 (-3.3A)
None
 0.43A 1oe2A-3sbqA:
8.2		 1oe2A-3sbqA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 2y69N-3sbqA:
undetectable		 2y69N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.78A 2zxwN-3sbqA:
undetectable		 2zxwN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.74A 3abmN-3sbqA:
undetectable		 3abmN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.75A 3ag1N-3sbqA:
undetectable		 3ag1N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3ag4N-3sbqA:
undetectable		 3ag4N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3asnA-3sbqA:
undetectable		 3asnA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 3asnN-3sbqA:
undetectable		 3asnN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 3asoA-3sbqA:
undetectable		 3asoA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 3asoN-3sbqA:
undetectable		 3asoN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 HIS A 129
HIS A 494
ASP A 127
HIS A  78
 CUK  A 702 (-3.5A)
CUK  A 702 (-3.3A)
None
None
 1.02A 3c0zA-3sbqA:
undetectable		 3c0zA-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 6 HIS A 129
HIS A 494
ASP A 127
HIS A  78
 CUK  A 702 (-3.5A)
CUK  A 702 (-3.3A)
None
None
 1.04A 3c0zC-3sbqA:
undetectable		 3c0zC-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 5 ASN A 324
ASN A 241
HIS A 382
ALA A 340
 CA  A 703 (-3.0A)
CL  A 704 (-3.7A)
CUK  A 702 ( 3.3A)
None
 1.49A 3frqA-3sbqA:
undetectable		 3frqA-3sbqA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 130
HIS A 178
HIS A 129
HIS A 326
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
CUK  A 702 (-3.1A)
 0.94A 3w6hA-3sbqA:
undetectable		 3w6hA-3sbqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 12 VAL A 155
ILE A 222
ILE A 497
GLU A 440
HIS A 178
 None
None
None
None
CUK  A 702 (-3.1A)
 1.19A 4a97B-3sbqA:
undetectable
4a97C-3sbqA:
undetectable		 4a97B-3sbqA:
19.40
4a97C-3sbqA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.87A 4p6sA-3sbqA:
undetectable		 4p6sA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 4p6sB-3sbqA:
undetectable		 4p6sB-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 ALA A 193
HIS A 130
ASN A 148
THR A 242
 None
CUK  A 702 (-3.2A)
None
None
 1.20A 5db5A-3sbqA:
undetectable
5db5B-3sbqA:
undetectable		 5db5A-3sbqA:
21.34
5db5B-3sbqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.88A 5i3aA-3sbqA:
undetectable		 5i3aA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.89A 5i3aB-3sbqA:
undetectable		 5i3aB-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.86A 5i3bA-3sbqA:
undetectable		 5i3bA-3sbqA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 5m8rA-3sbqA:
undetectable		 5m8rA-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.94A 5m8rB-3sbqA:
undetectable		 5m8rB-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.93A 5m8rC-3sbqA:
undetectable		 5m8rC-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 8 HIS A 494
HIS A 130
ASN A 148
HIS A 178
 CUK  A 702 (-3.3A)
CUK  A 702 (-3.2A)
None
CUK  A 702 (-3.1A)
 0.92A 5m8rD-3sbqA:
undetectable		 5m8rD-3sbqA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 ASP A 240
HIS A 178
HIS A 130
HIS A 326
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
 1.42A 5ncdD-3sbqA:
undetectable		 5ncdD-3sbqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.69A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.78A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.76A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 0.96A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.25A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 433
HIS A 494
HIS A 129
 CUK  A 702 (-3.1A)
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.53A 5oexA-3sbqA:
25.2		 5oexA-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.64A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.71A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 1.07A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.28A 5oexB-3sbqA:
7.3		 5oexB-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.67A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.67A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.75A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC602_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.28A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 1.04A 5oexC-3sbqA:
8.9		 5oexC-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
ASP A 127
HIS A 129
 None
None
CUK  A 702 (-3.5A)
 0.70A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 178
ASP A 240
HIS A 326
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.68A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A 326
ASP A 240
HIS A 178
 CUK  A 702 (-3.1A)
None
CUK  A 702 (-3.1A)
 0.76A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 LYS A 150
HIS A 178
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.5A)
 0.97A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD604_0
(THIOCYANATE
DEHYDROGENASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		4 / 4 LYS A 150
HIS A 178
HIS A 130
HIS A 129
 None
CUK  A 702 (-3.1A)
CUK  A 702 (-3.2A)
CUK  A 702 (-3.5A)
 1.23A 5oexD-3sbqA:
7.2		 5oexD-3sbqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 5x1fA-3sbqA:
undetectable		 5x1fA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 5xdqA-3sbqA:
undetectable		 5xdqA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.76A 5xdqN-3sbqA:
undetectable		 5xdqN-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		5 / 11 HIS A 130
HIS A 178
HIS A 326
HIS A 382
HIS A 494
 CUK  A 702 (-3.2A)
CUK  A 702 (-3.1A)
CUK  A 702 (-3.1A)
CUK  A 702 ( 3.3A)
CUK  A 702 (-3.3A)
 1.14A 5z0mA-3sbqA:
undetectable
5z0mB-3sbqA:
undetectable		 5z0mA-3sbqA:
8.46
5z0mB-3sbqA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.73A 5z86A-3sbqA:
undetectable		 5z86A-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.77A 5z86N-3sbqA:
undetectable		 5z86N-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.72A 6nmpA-3sbqA:
undetectable		 6nmpA-3sbqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3sbq NITROUS-OXIDE
REDUCTASE
(Pseudomonas
stutzeri) 		3 / 3 HIS A  78
HIS A 494
HIS A 129
 None
CUK  A 702 (-3.3A)
CUK  A 702 (-3.5A)
 0.72A 6nmpN-3sbqA:
undetectable		 6nmpN-3sbqA:
21.05