SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CTT'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C8L_A_CFFA940_1 (PROTEIN (GLYCOGEN PHOSPHORYLASE))	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.07A	1c8lA-5h4rA: undetectable	1c8lA-5h4rA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GFZ_A_CFFA940_1 (GLYCOGEN PHOSPHORYLASE)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.09A	1gfzA-5h4rA: undetectable	1gfzA-5h4rA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	5 / 10	GLU A 440 TYR A 131 GLN A 29 TYR A 315 GLY A 386	CTT A1001 (-2.7A) None CTT A1001 (-3.0A) CTT A1001 (-4.2A) None	1.50A	1httA-4qljA: undetectable	1httA-4qljA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5Q_A_CFFA863_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.08A	1l5qA-5h4rA: undetectable	1l5qA-5h4rA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5Q_B_CFFB1863_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.09A	1l5qB-5h4rA: undetectable	1l5qB-5h4rA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7X_A_CFFA863_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.06A	1l7xA-5h4rA: undetectable	1l7xA-5h4rA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L7X_B_CFFB1863_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.11A	1l7xB-5h4rA: undetectable	1l7xB-5h4rA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK2_A_ACAA91_1 (TISSUE-TYPE PLASMINOGEN ACTIVATOR)	4hu0	CELLULASE (uncultured bacterium)	4 / 8	ASP A 331 ASP A 333 TRP A 334 HIS A 111	None None CTT A 401 ( 3.8A) CTT A 401 (-3.7A)	1.20A	1pk2A-4hu0A: undetectable	1pk2A-4hu0A: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_SAMB293_0 (GLYCINE N-METHYLTRANSFERASE)	4a05	CELLOBIOHYDROLASE FAMILY 6 (Chaetomium thermophilum)	5 / 12	TYR A 348 ASP A 431 ASN A 333 HIS A 297 ILE A 342	None None None CTT A 503 (-4.1A) None	1.34A	1xvaB-4a05A: undetectable	1xvaB-4a05A: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B25_B_SAMB602_0 (HYPOTHETICAL PROTEIN)	2e0p	ENDOGLUCANASE (Ruminiclostridiu m thermocellum)	5 / 12	THR A 390 GLY A 45 VAL A 279 ASP A 278 ILE A 227	None CTT A 800 ( 3.7A) None None None	1.10A	2b25B-2e0pA: undetectable	2b25B-2e0pA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_B_SAMB1500_0 (ASPARTOKINASE)	4hu0	CELLULASE (uncultured bacterium)	4 / 7	SER A 79 ASP A 331 TRP A 334 GLU A 289	None None CTT A 401 ( 3.8A) CTT A 401 (-2.9A)	1.05A	2cdqB-4hu0A: undetectable	2cdqB-4hu0A: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_A_NBVA1503_1 (GLUCOSYLCERAMIDASE)	2e0p	ENDOGLUCANASE (Ruminiclostridiu m thermocellum)	6 / 12	ASN A 185 GLU A 186 HIS A 283 TYR A 285 GLU A 359 TRP A 392	CTT A 800 (-3.2A) CTT A 800 ( 2.9A) CTT A 800 ( 4.9A) CTT A 800 (-4.0A) CTT A 800 (-2.6A) CTT A 800 ( 3.9A)	0.76A	2v3dA-2e0pA: 13.5	2v3dA-2e0pA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_A_NBVA1503_1 (GLUCOSYLCERAMIDASE)	4hu0	CELLULASE (uncultured bacterium)	6 / 12	ASN A 192 GLU A 193 HIS A 258 TYR A 260 GLU A 289 TRP A 328	CTT A 401 (-2.8A) CTT A 401 (-2.8A) None CTT A 401 (-4.3A) CTT A 401 (-2.9A) CTT A 401 (-3.8A)	0.64A	2v3dA-4hu0A: 6.8	2v3dA-4hu0A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_B_NBVB1504_1 (GLUCOSYLCERAMIDASE)	2e0p	ENDOGLUCANASE (Ruminiclostridiu m thermocellum)	5 / 11	ASN A 185 GLU A 186 TYR A 285 GLU A 359 TRP A 392	CTT A 800 (-3.2A) CTT A 800 ( 2.9A) CTT A 800 (-4.0A) CTT A 800 (-2.6A) CTT A 800 ( 3.9A)	0.86A	2v3dB-2e0pA: 13.0	2v3dB-2e0pA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3D_B_NBVB1504_1 (GLUCOSYLCERAMIDASE)	4hu0	CELLULASE (uncultured bacterium)	5 / 11	ASN A 192 GLU A 193 TYR A 260 GLU A 289 TRP A 328	CTT A 401 (-2.8A) CTT A 401 (-2.8A) CTT A 401 (-4.3A) CTT A 401 (-2.9A) CTT A 401 (-3.8A)	0.72A	2v3dB-4hu0A: 3.2	2v3dB-4hu0A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AF0_A_PAUA314_0 (PANTOTHENATE KINASE)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	4 / 8	VAL A 241 GLY A 386 TYR A 315 HIS A 130	None None CTT A1001 (-4.2A) CTT A1001 (-4.1A)	0.98A	3af0A-4qljA: undetectable	3af0A-4qljA: 18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BCR_A_AZZA940_1 (GLYCOGEN PHOSPHORYLASE, MUSCLE FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 5	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.10A	3bcrA-5h4rA: undetectable	3bcrA-5h4rA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD1_A_CFFA903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.11A	3dd1A-5h4rA: undetectable	3dd1A-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DD1_B_CFFB903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.06A	3dd1B-5h4rA: undetectable	3dd1B-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDS_A_CFFA904_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.09A	3ddsA-5h4rA: undetectable	3ddsA-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDS_B_CFFB903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.07A	3ddsB-5h4rA: undetectable	3ddsB-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDW_A_CFFA903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.08A	3ddwA-5h4rA: undetectable	3ddwA-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDW_B_CFFB903_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 6	ASN A 362 PHE A 372 ALA A 364 GLY A 369	CTT A 401 (-4.0A) CTT A 401 ( 4.5A) None None	1.08A	3ddwB-5h4rA: undetectable	3ddwB-5h4rA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E23_A_SAMA221_1 (UNCHARACTERIZED PROTEIN RPA2492)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	3 / 3	TYR A 468 ASP A 403 HIS A 462	CTT A1002 (-3.8A) None None	0.92A	3e23A-4qljA: undetectable	3e23A-4qljA: 17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_A_EAAA212_1 (GLUTATHIONE S-TRANSFERASE P1-1)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	4 / 7	VAL A 24 TYR A 315 THR A 316 GLY A 386	None CTT A1001 (-4.2A) None None	0.94A	3gssA-4qljA: undetectable	3gssA-4qljA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P1-1)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	4 / 7	VAL A 24 TYR A 315 THR A 316 GLY A 386	None CTT A1001 (-4.2A) None None	1.00A	3gssB-4qljA: undetectable	3gssB-4qljA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGG_A_CHDA211_0 (CMER)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	4 / 7	CYH A 357 PHE A 307 PHE A 327 TYR A 274	None None None CTT A 401 ( 3.6A)	1.40A	3hggA-5h4rA: 0.8	3hggA-5h4rA: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3008_1 (TRANSCRIPTIONAL REGULATOR TCAR)	4hu0	CELLULASE (uncultured bacterium)	4 / 7	GLU A 289 VAL A 326 VAL A 256 ARG A 107	CTT A 401 (-2.9A) None None None	1.07A	3kp6B-4hu0A: undetectable	3kp6B-4hu0A: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PO7_A_ZONA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4hu0	CELLULASE (uncultured bacterium)	4 / 8	TYR A 292 LEU A 338 PHE A 354 TYR A 260	None None None CTT A 401 (-4.3A)	1.33A	3po7A-4hu0A: undetectable	3po7A-4hu0A: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_C_SUEC1201_1 (NS3 PROTEASE, NS4A PROTEIN)	4hu0	CELLULASE (uncultured bacterium)	5 / 11	GLN A 157 PHE A 197 GLY A 149 ALA A 237 ALA A 232	CTT A 401 (-3.1A) CTT A 401 (-4.8A) None None None	1.19A	3sufC-4hu0A: undetectable	3sufC-4hu0A: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_D_ACTD502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2e0p	ENDOGLUCANASE (Ruminiclostridiu m thermocellum)	3 / 3	GLY A 44 THR A 108 ASN A 185	GOL A 601 (-3.9A) None CTT A 800 (-3.2A)	0.72A	3v4tD-2e0pA: 0.3	3v4tD-2e0pA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5h4r	BETA-1,3-1,4-GLUCANA SE (Caldicellulosiru ptor sp. F32)	5 / 12	ARG A 98 GLU A 184 TYR A 274 ASN A 187 HIS A 141	None None CTT A 401 ( 3.6A) CTT A 401 (-2.7A) CTT A 401 (-3.9A)	1.49A	3w2tB-5h4rA: undetectable	3w2tB-5h4rA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3U_A_NCAA1359_0 (NADH:FLAVIN OXIDOREDUCTASE/NADH OXIDASE)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	4 / 7	TRP A 337 ASN A 245 TYR A 247 TYR A 333	None CTT A1001 (-3.6A) None None	1.49A	4a3uA-4qljA: 13.4	4a3uA-4qljA: 22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_A_715A801_2 (DIPEPTIDYL PEPTIDASE 4)	4hu0	CELLULASE (uncultured bacterium)	3 / 3	PHE A 318 TYR A 260 TYR A 310	None CTT A 401 (-4.3A) None	0.87A	4ffwA-4hu0A: undetectable	4ffwA-4hu0A: 17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LRH_B_FOLB301_1 (FOLATE RECEPTOR ALPHA)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	3 / 3	ASP A 132 TRP A 433 SER A 88	None CTT A1001 (-3.5A) None	0.99A	4lrhB-4qljA: undetectable	4lrhB-4qljA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LRH_F_FOLF301_1 (FOLATE RECEPTOR ALPHA)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	3 / 3	ASP A 132 TRP A 433 SER A 88	None CTT A1001 (-3.5A) None	1.06A	4lrhF-4qljA: undetectable	4lrhF-4qljA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6S_A_DAHA304_1 (TYROSINASE)	4hu0	CELLULASE (uncultured bacterium)	4 / 5	ASN A 192 HIS A 146 GLU A 189 THR A 288	CTT A 401 (-2.8A) CTT A 401 (-3.7A) None None	1.42A	4p6sA-4hu0A: undetectable	4p6sA-4hu0A: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4qlj	BETA-GLUCOSIDASE 7 (Oryza sativa)	3 / 3	ASN A 175 PHE A 431 TYR A 85	CTT A1001 (-3.1A) None None	0.67A	4u15A-4qljA: undetectable	4u15A-4qljA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	5gly	GLYCOSIDE HYDROLASE FAMILY 45 PROTEIN (Thielavia terrestris)	5 / 12	GLY A 129 GLY A 149 ALA A 75 THR A 110 ALA A 124	CTR A 302 (-3.5A) CTR A 302 (-3.7A) CTT A 301 (-3.5A) None None	1.15A	4uckB-5glyA: undetectable	4uckB-5glyA: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE5_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	4a05	CELLOBIOHYDROLASE FAMILY 6 (Chaetomium thermophilum)	5 / 12	GLU A 250 ASP A 294 LEU A 330 ALA A 310 ASP A 206	None None None None CTT A 503 (-3.1A)	1.08A	4xe5A-4a05A: undetectable	4xe5A-4a05A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7P_A_SAMA501_1 (OXAC)	4hu0	CELLULASE (uncultured bacterium)	4 / 5	HIS A 146 ASP A 80 ASP A 85 ARG A 107	CTT A 401 (-3.7A) None None None	1.32A	5w7pA-4hu0A: 0.4	5w7pA-4hu0A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W7P_A_SAMA501_1 (OXAC)	4hu0	CELLULASE (uncultured bacterium)	4 / 5	TYR A 123 HIS A 146 ASP A 80 ASP A 85	None CTT A 401 (-3.7A) None None	1.33A	5w7pA-4hu0A: 0.4	5w7pA-4hu0A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIO_A_HFGA801_1 (PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE))	4hu0	CELLULASE (uncultured bacterium)	3 / 3	THR A 288 GLU A 189 HIS A 146	None None CTT A 401 (-3.7A)	0.89A	5xioA-4hu0A: undetectable	5xioA-4hu0A: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_B_HFGB1002_1 (PROLYL-TRNA SYNTHETASE (PRORS))	4hu0	CELLULASE (uncultured bacterium)	3 / 3	THR A 288 GLU A 189 HIS A 146	None None CTT A 401 (-3.7A)	0.83A	5xiqB-4hu0A: undetectable	5xiqB-4hu0A: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_D_HFGD1002_1 (PROLYL-TRNA SYNTHETASE (PRORS))	4hu0	CELLULASE (uncultured bacterium)	3 / 3	THR A 288 GLU A 189 HIS A 146	None None CTT A 401 (-3.7A)	0.85A	5xiqD-4hu0A: undetectable	5xiqD-4hu0A: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C71_B_NCTB501_1 (AMINE OXIDASE)	2e0p	ENDOGLUCANASE (Ruminiclostridiu m thermocellum)	4 / 8	TRP A 392 LEU A 72 TYR A 71 THR A 48	CTT A 800 ( 3.9A) None CTT A 800 (-3.7A) None	1.10A	6c71B-2e0pA: undetectable	6c71B-2e0pA: 15.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C8L_A_CFFA940_1","PROTEIN (GLYCOGEN PHOSPHORYLASE)","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.07A","1c8lA-5h4rA:undetectable",null],["1GFZ_A_CFFA940_1","GLYCOGEN PHOSPHORYLASE","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.09A","1gfzA-5h4rA:undetectable","1c8lA-5h4rA:18.94"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",5,"GLU A 440;TYR A 131;GLN A  29;TYR A 315;GLY A 386","CTT A1001 (-2.7A);None;CTT A1001 (-3.0A);CTT A1001 (-4.2A);None","1.50A","1httA-4qljA:undetectable","1gfzA-5h4rA:18.94"],["1L5Q_A_CFFA863_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.08A","1l5qA-5h4rA:undetectable","1httA-4qljA:23.40"],["1L5Q_B_CFFB1863_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.09A","1l5qB-5h4rA:undetectable","1l5qA-5h4rA:18.75"],["1L7X_A_CFFA863_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.06A","1l7xA-5h4rA:undetectable","1l5qB-5h4rA:18.75"],["1L7X_B_CFFB1863_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.11A","1l7xB-5h4rA:undetectable","1l7xA-5h4rA:18.75"],["1PK2_A_ACAA91_1","TISSUE-TYPE PLASMINOGEN ACTIVATOR","4hu0","CELLULASE","uncultured bacterium",4,"ASP A 331;ASP A 333;TRP A 334;HIS A 111","None;None;CTT A 401 ( 3.8A);CTT A 401 (-3.7A)","1.20A","1pk2A-4hu0A:undetectable","1l7xB-5h4rA:18.75"],["1XVA_B_SAMB293_0","GLYCINE N-METHYLTRANSFERASE","4a05","CELLOBIOHYDROLASE FAMILY 6","Chaetomium thermophilum",5,"TYR A 348;ASP A 431;ASN A 333;HIS A 297;ILE A 342","None;None;None;CTT A 503 (-4.1A);None","1.34A","1xvaB-4a05A:undetectable","1pk2A-4hu0A:12.46"],["2B25_B_SAMB602_0","HYPOTHETICAL PROTEIN","2e0p","ENDOGLUCANASE","Ruminiclostridium thermocellum",5,"THR A 390;GLY A  45;VAL A 279;ASP A 278;ILE A 227","None;CTT A 800 ( 3.7A);None;None;None","1.10A","2b25B-2e0pA:undetectable","1xvaB-4a05A:23.04"],["2CDQ_B_SAMB1500_0","ASPARTOKINASE","4hu0","CELLULASE","uncultured bacterium",4,"SER A  79;ASP A 331;TRP A 334;GLU A 289","None;None;CTT A 401 ( 3.8A);CTT A 401 (-2.9A)","1.05A","2cdqB-4hu0A:undetectable","2b25B-2e0pA:21.62"],["2V3D_A_NBVA1503_1","GLUCOSYLCERAMIDASE","2e0p","ENDOGLUCANASE","Ruminiclostridium thermocellum",6,"ASN A 185;GLU A 186;HIS A 283;TYR A 285;GLU A 359;TRP A 392","CTT A 800 (-3.2A);CTT A 800 ( 2.9A);CTT A 800 ( 4.9A);CTT A 800 (-4.0A);CTT A 800 (-2.6A);CTT A 800 ( 3.9A)","0.76A","2v3dA-2e0pA:13.5","2cdqB-4hu0A:19.85"],["2V3D_A_NBVA1503_1","GLUCOSYLCERAMIDASE","4hu0","CELLULASE","uncultured bacterium",6,"ASN A 192;GLU A 193;HIS A 258;TYR A 260;GLU A 289;TRP A 328","CTT A 401 (-2.8A);CTT A 401 (-2.8A);None;CTT A 401 (-4.3A);CTT A 401 (-2.9A);CTT A 401 (-3.8A)","0.64A","2v3dA-4hu0A:6.8","2v3dA-2e0pA:22.64"],["2V3D_B_NBVB1504_1","GLUCOSYLCERAMIDASE","2e0p","ENDOGLUCANASE","Ruminiclostridium thermocellum",5,"ASN A 185;GLU A 186;TYR A 285;GLU A 359;TRP A 392","CTT A 800 (-3.2A);CTT A 800 ( 2.9A);CTT A 800 (-4.0A);CTT A 800 (-2.6A);CTT A 800 ( 3.9A)","0.86A","2v3dB-2e0pA:13.0","2v3dA-4hu0A:21.14"],["2V3D_B_NBVB1504_1","GLUCOSYLCERAMIDASE","4hu0","CELLULASE","uncultured bacterium",5,"ASN A 192;GLU A 193;TYR A 260;GLU A 289;TRP A 328","CTT A 401 (-2.8A);CTT A 401 (-2.8A);CTT A 401 (-4.3A);CTT A 401 (-2.9A);CTT A 401 (-3.8A)","0.72A","2v3dB-4hu0A:3.2","2v3dB-2e0pA:22.64"],["3AF0_A_PAUA314_0","PANTOTHENATE KINASE","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",4,"VAL A 241;GLY A 386;TYR A 315;HIS A 130","None;None;CTT A1001 (-4.2A);CTT A1001 (-4.1A)","0.98A","3af0A-4qljA:undetectable","2v3dB-4hu0A:21.14"],["3BCR_A_AZZA940_1","GLYCOGEN PHOSPHORYLASE, MUSCLE FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.10A","3bcrA-5h4rA:undetectable","3af0A-4qljA:18.05"],["3DD1_A_CFFA903_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.11A","3dd1A-5h4rA:undetectable","3bcrA-5h4rA:18.94"],["3DD1_B_CFFB903_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.06A","3dd1B-5h4rA:undetectable","3dd1A-5h4rA:18.56"],["3DDS_A_CFFA904_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.09A","3ddsA-5h4rA:undetectable","3dd1B-5h4rA:18.56"],["3DDS_B_CFFB903_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.07A","3ddsB-5h4rA:undetectable","3ddsA-5h4rA:18.56"],["3DDW_A_CFFA903_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.08A","3ddwA-5h4rA:undetectable","3ddsB-5h4rA:18.56"],["3DDW_B_CFFB903_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"ASN A 362;PHE A 372;ALA A 364;GLY A 369","CTT A 401 (-4.0A);CTT A 401 ( 4.5A);None;None","1.08A","3ddwB-5h4rA:undetectable","3ddwA-5h4rA:18.56"],["3E23_A_SAMA221_1","UNCHARACTERIZED PROTEIN RPA2492","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",3,"TYR A 468;ASP A 403;HIS A 462","CTT A1002 (-3.8A);None;None","0.92A","3e23A-4qljA:undetectable","3ddwB-5h4rA:18.56"],["3GSS_A_EAAA212_1","GLUTATHIONE S-TRANSFERASE P1-1","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",4,"VAL A  24;TYR A 315;THR A 316;GLY A 386","None;CTT A1001 (-4.2A);None;None","0.94A","3gssA-4qljA:undetectable","3e23A-4qljA:17.08"],["3GSS_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P1-1","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",4,"VAL A  24;TYR A 315;THR A 316;GLY A 386","None;CTT A1001 (-4.2A);None;None","1.00A","3gssB-4qljA:undetectable","3gssA-4qljA:17.05"],["3HGG_A_CHDA211_0","CMER","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",4,"CYH A 357;PHE A 307;PHE A 327;TYR A 274","None;None;None;CTT A 401 ( 3.6A)","1.40A","3hggA-5h4rA:0.8","3gssB-4qljA:17.05"],["3KP6_B_SALB3008_1","TRANSCRIPTIONAL REGULATOR TCAR","4hu0","CELLULASE","uncultured bacterium",4,"GLU A 289;VAL A 326;VAL A 256;ARG A 107","CTT A 401 (-2.9A);None;None;None","1.07A","3kp6B-4hu0A:undetectable","3hggA-5h4rA:22.84"],["3PO7_A_ZONA601_1","AMINE OXIDASE [FLAVIN-CONTAINING] B","4hu0","CELLULASE","uncultured bacterium",4,"TYR A 292;LEU A 338;PHE A 354;TYR A 260","None;None;None;CTT A 401 (-4.3A)","1.33A","3po7A-4hu0A:undetectable","3kp6B-4hu0A:16.62"],["3SUF_C_SUEC1201_1","NS3 PROTEASE, NS4A PROTEIN","4hu0","CELLULASE","uncultured bacterium",5,"GLN A 157;PHE A 197;GLY A 149;ALA A 237;ALA A 232","CTT A 401 (-3.1A);CTT A 401 (-4.8A);None;None;None","1.19A","3sufC-4hu0A:undetectable","3po7A-4hu0A:21.48"],["3V4T_D_ACTD502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2e0p","ENDOGLUCANASE","Ruminiclostridium thermocellum",3,"GLY A  44;THR A 108;ASN A 185","GOL A 601 (-3.9A);None;CTT A 800 (-3.2A)","0.72A","3v4tD-2e0pA:0.3","3sufC-4hu0A:20.47"],["3W2T_B_LF7B801_1","DIPEPTIDYL PEPTIDASE 4","5h4r","BETA-1,3-1,4-GLUCANASE","Caldicellulosiruptor sp. F32",5,"ARG A  98;GLU A 184;TYR A 274;ASN A 187;HIS A 141","None;None;CTT A 401 ( 3.6A);CTT A 401 (-2.7A);CTT A 401 (-3.9A)","1.49A","3w2tB-5h4rA:undetectable","3v4tD-2e0pA:23.44"],["4A3U_A_NCAA1359_0","NADH:FLAVIN OXIDOREDUCTASE\/NADH OXIDASE","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",4,"TRP A 337;ASN A 245;TYR A 247;TYR A 333","None;CTT A1001 (-3.6A);None;None","1.49A","4a3uA-4qljA:13.4","3w2tB-5h4rA:20.45"],["4FFW_A_715A801_2","DIPEPTIDYL PEPTIDASE 4","4hu0","CELLULASE","uncultured bacterium",3,"PHE A 318;TYR A 260;TYR A 310","None;CTT A 401 (-4.3A);None","0.87A","4ffwA-4hu0A:undetectable","4a3uA-4qljA:22.49"],["4LRH_B_FOLB301_1","FOLATE RECEPTOR ALPHA","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",3,"ASP A 132;TRP A 433;SER A  88","None;CTT A1001 (-3.5A);None","0.99A","4lrhB-4qljA:undetectable","4ffwA-4hu0A:17.76"],["4LRH_F_FOLF301_1","FOLATE RECEPTOR ALPHA","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",3,"ASP A 132;TRP A 433;SER A  88","None;CTT A1001 (-3.5A);None","1.06A","4lrhF-4qljA:undetectable","4lrhB-4qljA:16.43"],["4P6S_A_DAHA304_1","TYROSINASE","4hu0","CELLULASE","uncultured bacterium",4,"ASN A 192;HIS A 146;GLU A 189;THR A 288","CTT A 401 (-2.8A);CTT A 401 (-3.7A);None;None","1.42A","4p6sA-4hu0A:undetectable","4lrhF-4qljA:16.43"],["4U15_A_0HKA2001_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","4qlj","BETA-GLUCOSIDASE 7","Oryza sativa",3,"ASN A 175;PHE A 431;TYR A  85","CTT A1001 (-3.1A);None;None","0.67A","4u15A-4qljA:undetectable","4p6sA-4hu0A:20.47"],["4UCK_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","5gly","GLYCOSIDE HYDROLASE FAMILY 45 PROTEIN","Thielavia terrestris",5,"GLY A 129;GLY A 149;ALA A  75;THR A 110;ALA A 124","CTR A 302 (-3.5A);CTR A 302 (-3.7A);CTT A 301 (-3.5A);None;None","1.15A","4uckB-5glyA:undetectable","4u15A-4qljA:21.56"],["4XE5_A_OBNA1104_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","4a05","CELLOBIOHYDROLASE FAMILY 6","Chaetomium thermophilum",5,"GLU A 250;ASP A 294;LEU A 330;ALA A 310;ASP A 206","None;None;None;None;CTT A 503 (-3.1A)","1.08A","4xe5A-4a05A:undetectable","4uckB-5glyA:17.66"],["5W7P_A_SAMA501_1","OXAC","4hu0","CELLULASE","uncultured bacterium",4,"HIS A 146;ASP A  80;ASP A  85;ARG A 107","CTT A 401 (-3.7A);None;None;None","1.32A","5w7pA-4hu0A:0.4","4xe5A-4a05A:16.67"],["5W7P_A_SAMA501_1","OXAC","4hu0","CELLULASE","uncultured bacterium",4,"TYR A 123;HIS A 146;ASP A  80;ASP A  85","None;CTT A 401 (-3.7A);None;None","1.33A","5w7pA-4hu0A:0.4","5w7pA-4hu0A:23.13"],["5XIO_A_HFGA801_1","PROLINE-TRNA SYNTHETASE CLASS II AARS (YBAK RNA BINDING DOMAIN PLUS TRNA SYNTHETASE)","4hu0","CELLULASE","uncultured bacterium",3,"THR A 288;GLU A 189;HIS A 146","None;None;CTT A 401 (-3.7A)","0.89A","5xioA-4hu0A:undetectable","5w7pA-4hu0A:23.13"],["5XIQ_B_HFGB1002_1","PROLYL-TRNA SYNTHETASE (PRORS)","4hu0","CELLULASE","uncultured bacterium",3,"THR A 288;GLU A 189;HIS A 146","None;None;CTT A 401 (-3.7A)","0.83A","5xiqB-4hu0A:undetectable","5xioA-4hu0A:20.80"],["5XIQ_D_HFGD1002_1","PROLYL-TRNA SYNTHETASE (PRORS)","4hu0","CELLULASE","uncultured bacterium",3,"THR A 288;GLU A 189;HIS A 146","None;None;CTT A 401 (-3.7A)","0.85A","5xiqD-4hu0A:undetectable","5xiqB-4hu0A:20.50"],["6C71_B_NCTB501_1","AMINE OXIDASE","2e0p","ENDOGLUCANASE","Ruminiclostridium thermocellum",4,"TRP A 392;LEU A  72;TYR A  71;THR A  48","CTT A 800 ( 3.9A);None;CTT A 800 (-3.7A);None","1.10A","6c71B-2e0pA:undetectable","5xiqD-4hu0A:20.50"]]